Requirement for phosphatidylinositol 3′-kinase activity in platelet-derived growth factor-stimulated tyrosine phosphorylation of p125 focal adhesion kinase and paxillin

Journal of Biological Chemistry

Volumn 271, Issue 13, 1996, Pages 7829-7834

  Rankin, Sara ^a   Hooshmand Rad, Roya ^b   Claesson Welsh, Lena ^b   Rozengurt, Enrique ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b LUDWIG INSTITUTE FOR CANCER RESEARCH   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

SUIDAE; ANIMALIA; SUS SCROFA;

2 MORPHOLINO 8 PHENYLCHROMONE; BOMBESIN; ENDOTHELIN; PAXILLIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE P 125; PROTEIN TYROSINE KINASE; RAPAMYCIN; RECOMBINANT PLATELET DERIVED GROWTH FACTOR; UNCLASSIFIED DRUG; WORTMANNIN;

ANIMAL CELL; AORTA; ARTICLE; ENDOTHELIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SWINE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3 CELLS; ANDROSTADIENES; ANIMALS; BOMBESIN; CELL ADHESION MOLECULES; CYTOSKELETAL PROTEINS; ENDOTHELINS; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; KINETICS; MICE; MUTAGENESIS, SITE-DIRECTED; PAXILLIN; PHOSPHOPROTEINS; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PHOSPHOTYROSINE; PLATELET-DERIVED GROWTH FACTOR; POINT MUTATION; PROTEIN-TYROSINE KINASES; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TYROSINE;

EID: 0029947181     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.13.7829     Document Type: Article

References (67)

1. Ross, R., Raines, E. W., and Bowen-Pope, D. F. (1986) Cell 46, 155-169
2. Heldin, C.-H. (1992) EMBO J. 11, 4251-4259
3. Claesson-Welsh, L. (1994) J. Biol. Chem. 269, 32023-32026
4. Kelly, J. D., Halderman, B. A., Grant, F. J., Murray, M. J., Seifert, R. A., Bowen-Pope, D. F., Cooper, J. A., and Kazlauskas, A. (1991) J. Biol. Chem. 266, 8987-8992
5. Kumjian, D. A., Wahl, M. I., Rhee, S. G., and Daniel, T. O. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 8232-8236
6. Meisenhelder, J., Sah, P. G., Rhee, S. G., and Hunter, T. (1989) Cell 57, 1109-1122
7. Wahl, M. I., Olashaw, N. E., Nishibe, S., Rhee, S. G., Pledger, W. J., and Carpenter, G. (1989) Mol. Cell. Biol. 9, 2934-2943
8. Morrison, D. K., Kaplan, D. R., Rhee, S. G., and Williams, L. T. (1990) Mol. Cell. Biol. 10, 2359-2366
9. Feng, G. S., Hui, C. C., and Pawson, T. (1993) Science 259, 1607-1611
10. Kazlauskas, A., Ellis, C., Pawson, T., and Copper, J. A. (1990) Science 247, 1578-1581
11. Kaplan, D. R., Morrison, D. K., Wong, G., McCormick, F., and Williams, L. T. (1990) Cell 61, 125-133
12. Kaplan, D. R., Whitman, M., Schaffhausen, B., Pallas, D. C., White, M., Cantley, L., and Roberts, T. M. (1987) Cell 50, 1021-1029
13. Kazlauskas, A., and Cooper, J. A. (1989) Cell 58, 1121-1133
14. Lowenstein, E. J., Daly, R. J., Batzer, A. G., Li, W., Margolis, B., Lammers, R., Ullrich, A., Skolnik, E. Y., Bar-Sagi, D., and Schlessinger, J. (1992) Cell 70, 431-442
15. Kypta, R. M., Goldberg, Y., Ulug, E. T., and Courtneidge, S. A. (1990) Cell 62, 481-492
16. Anderson, D., Koch, C. A., Grey, L., Ellis, C., Moran, M. F., and Pawson, T. (1990) Science 250, 979-982
17. Koch, C. A., Andersen, D., Moran, M. F., Ellis, C., and Pawson, T. (1991) Science 252, 668-674
18. Rankin, S., and Rozengurt, E. (1994) J. Biol. Chem. 269, 704-710
19. Chen, H.-C., and Guan, J.-L. (1994) J. Biol. Chem. 269, 31229-31233
20. Hanks, S. K., Calalb, M. B., Harper, M. C., and Patel, S. K. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 8487-8491
21. Schaller, M. D., Borgman, C. A., Cobb, B. S., Vines, R. R., Reynolds, A. B., and Parsons, J. T. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 5192-5196
22. Cobb, B. S., Schaller, M. D., Leu, T.-H., and Parsons, J. T. (1994) Mol. Cell. Biol. 14, 147-155
23. Schlaepfer, D. D., Hanks, S., Hunter, T., and van der Geer, P. (1994) Nature 372, 786-791
24. Hildebrand, J. D., Schaller, M. D., and Parsons, J. T. (1995) Mol. Biol. Cell 6, 637-647
25. Turner, C. E., and Miller, J. T. (1994) J. Cell Sci. 107, 1583-1591
26. Turner, C. E., Glenney, J. R., Jr., and Burridge, K. (1990) J. Cell Biol. 111, 1059-1068
27. Downes, C. P., and Carter, A. N. (1991) Cell Signal 3, 501-503
28. Stephens, L. R., Jackson, T. R., and Hawkins, P. T. (1993) Biochim. Biophys. Acta 1179, 27-75
29. Auger, K. R., Serunian, L. A., Soltoff, S. P., Libby, P., and Cantley, L. (1989) Cell 57, 167-175
30. Stephens, L. R., Hughes, K. T., and Irvine, R. F. (1991) Nature 351, 33-39
31. Hawkins, P. T., Jackson, T. R., and Stephens, L. R. (1992) Nature 358, 157-159
32. Chung, J., Grammer, T. C., Lemon, K. P., Kazlauskas, A., and Blenis, J. (1994) Nature 370, 71-74
33. Weng, Q.-P., Andrabi, K., Klippel, A., Kozlowski, M. T., Williams, L. T., and Avruch, J. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 5744-5748
34. Weng, Q.-P., Andrabi, K., Kozlowski, M. T., Grove, J. R., and Avruch, J. (1995) Mol. Cell. Biol. 15, 2333-2340
35. Monfar, M., Lemon, K. P., Grammer, T. C., Cheatham, L., Chung, J., Vlahos, C. J., and Blenis, J. (1995) Mol. Cell. Biol. 15, 326-337
36. Ming, X.-F., Burgering, B. M. T., Wennström, S., Claesson-Welsh, L., Heldin, C.-H., Bos, J. L., Kozma, S. C., and Thomas, G. (1994) Nature 371, 426-429
37. Wennström, S., Siegbahn, A., Yokote, K., Arvidisson, A.-K., Heldin, C.-H., Mori, S., and Claesson-Walsh, L. (1994) Oncogene 9, 651-660
38. Wennström, S., Hawkins, P., Cooke, F., Hara, K., Yonezawa, K., Kasuga, M., Jackson, T., Claesson-Welsh, L., and Stephens, L. (1994) Curr. Biol. 4, 385-393
39. Wymanin, M., and Arcaro, A. (1994) Biochem. J. 298, 517-520
40. Todaro, G. J., and Green, H. (1963) J. Cell Biol. 17, 299-313
41. Dicker, P., and Rozengurt, E. (1980) Nature 287, 607-612
42. Mori, S., Ronnstrand, L., Yokote, K., Engstrom, A., Courtneidge, S. A., Claesson-Welsh, L., and Heldin, C.-H. (1993) EMBO J. 12, 2257-2264
43. Claesson-Welsh, L., Eriksson, A., Moren, A., Severinsson, L., Ek, B., Ostman, A., Betsholtz, C., and Heldin, C.-H. (1988) Mol. Cell. Biol. 8, 3476-3486
44. Zachary, I., Sinnett-Smith, J., and Rozengurt, E. (1992) J. Biol. Chem. 267, 19031-19034
45. Zachary, I., Gil, J., Lehmann, W., Sinnett-Smith, J., and Rozengurt, E. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 4577-4581
46. Ferrari, S., Bannwarth, W., Morley, S. J., Totty, N. F., and Thomas, G. (1990) Proc. Natl. Acad. Sci. U. S. A. 89, 7282-7285
47. Chung, J., Kuo, C. J., Crabtree, G. R., and Blenis, J. (1992) Cell 69, 1227-1236
48. Whitman, M., Kaplan, D. R., Schaffhausen, B., Cantley, L., and Roberts, T. M. (1985) Nature 315, 239-242
49. Yano, H., Nakanishi, S., Kimura, K., Hanai, N., Saitoh, Y., Fukui, Y., Nonomura, Y., and Matsuda, Y. (1993) J. Biol. Chem. 268, 25846-25856
50. Okada, T., Sakuma, L., Fukui, Y., Hazeki, O., and Ui, M. (1994) J. Biol. Chem. 269, 3563-3567
51. Powis, G., Bonjouklian, R., Berggren, M. M., Gallegos, A., Abraham, R., Ashendel, C., Zalkow, L., Matter, W. F., Dodge, J., Grindey, G., and Vlahos, C. J. (1994) Cancer Res. 54, 2419-2423
52. Kapeller, R., and Cantley, L. C. (1994) BioEssays 16, 565-576
53. Rozengurt, E. (1992) Curr. Opin. Cell Biol. 4, 161-165
54. Jackson, T. R., Stephens, L. R., and Hawkins, P. T. (1992) J. Biol. Chem. 267, 16627-16636
55. Nobes, C. D., Hawkins, P., Stephens, L., and Hall, A. (1995) J. Cell Sci. 108, 225-233
56. Sinnett-Smith, J., Zachary, I., Valverde, A. M., and Rozengurt, E. (1993) J. Biol. Chem. 268, 14261-14268
57. Rankin, S., Morii, N., Narumiya, S., and Rozengurt, E. (1994) FEBS Lett. 354, 315-319
58. Vlahos, C. J., Matter, W. F., Hui, K. Y., and Brown, R. F. (1994) J. Biol Chem. 269, 5241-5248
59. Hawkins, P. T., Eguinoa, A., Qui, R.-G., Stokoe, D., Cooke, F. T., Walters, R., Wennström, S., Claesson-Welsh, L., Evans, T., Symons, M., and Stephens, L. (1995) Curr. Biol. 5, 393-403
60. Zachary, I., Sinnett-Smith, J., Turner, C. E., and Rozengurt, E. (1993) J. Biol. Chem. 268, 22060-22065
61. Rozengurt, E. (1995) Cancer Surveys 24, 81-96
62. Ferrari, S., and Thomas, G. (1994) Crit. Rev. Biochem. Mol. Biol. 29, 385-413
63. Tolias, K. F., Cantley, L. C., and Carpenter, C. L. (1995) J. Biol. Chem. 270, 17656-17659
64. Ridley, A. J., and Hall, A. (1992) Cell 70, 389-399
65. Llic, D., Furuta, Y., Kanazawa, S., Takeda, N., Sobue, K., Nakatsuji, N., Nomura, S., Fujimoto, J., Okada, M., Yamamoto, T., and Aizawa, S. (1995) Nature 377, 539-544
66. Sjolander, A., Yamamoto, K., Huber, B. E., and Lapetina, E. G. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 7908-7912
67. Rodriguez-Viciana, P., Warne, P. H., Dhand, R., Vanhaesebroeke, B., Gout, I., Fry, M. J., Waterfield, M. D., and Downward, J. (1994) Nature 370, 527-532