Polymerization of 2'-fluoro- and 2'-O-methyl-dNTPs by human DNA polymerase α, polymerase γ, and primase

Biochemical Pharmacology

Volumn 59, Issue 9, 2000, Pages 1045-1052

  Richardson, Frank C ^a   Kuchta, Robert D ^b   Mazurkiewicz, Anna ^a   Richardson, Katherine A ^c  

^a GILEAD SCIENCES   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c Molecular Experimental Design   (United States)

Author keywords

2' fluoronucleoside triphosphate; 2' O methoxynucleoside triphosphate; DNA primase; Human; Polymerase ; Polymerase

Indexed keywords

1 (2' DEOXY 2' FLUORO ARABINOFURANOSYL) 5 IODOURACIL TRIPHOSPHATE; 2' DEOXY 2' FLUOROADENOSINE TRIPHOSPHATE; 2' DEOXY 2' FLUOROCYTIDINE TRIPHOSPHATE; 2' DEOXY 2' FLUOROGUANOSINE TRIPHOSPHATE; 2' DEOXY 2' FLUOROURIDINE TRIPHOSPHATE; 2' DEOXYURIDINE TRIPHOSPHATE; DEOXYRIBONUCLEOTIDE; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE GAMMA; DNA PRIMASE; UNCLASSIFIED DRUG; URIDINE TRIPHOSPHATE;

ARTICLE; DNA SYNTHESIS; DNA TEMPLATE; ENZYME ACTIVITY; ENZYME SPECIFICITY; IN VITRO STUDY; ISOTOPE LABELING; POLYMERIZATION; PRIORITY JOURNAL; REACTION ANALYSIS;

DEOXYCYTOSINE NUCLEOTIDES; DEOXYGUANINE NUCLEOTIDES; DEOXYRIBONUCLEOTIDES; DNA POLYMERASE I; DNA PRIMASE; DNA-DIRECTED DNA POLYMERASE; HUMANS; THYMINE NUCLEOTIDES; URIDINE TRIPHOSPHATE;

EID: 0033954635     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(99)00414-1     Document Type: Article

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