Pooled genotyping of microsatellite markers in parent-offspring trios

Genome Research

Volumn 10, Issue 1, 2000, Pages 105-115

  Kirov, George ^a   Williams, Nigel ^a   Sham, Pak ^b   Craddock, Nick ^c   Owen, Michael J ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MICROSATELLITE DNA;

ACCURACY; ARTICLE; CONTROLLED STUDY; DNA DETERMINATION; DNA POLYMORPHISM; ERROR; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENOTYPE; HUMAN; HUMAN CELL; MARKER GENE; PRIORITY JOURNAL; PROGENY;

BIPOLAR DISORDER; CASE-CONTROL STUDIES; CHILD; CHROMOSOMES, HUMAN, PAIR 4; DNA; FALSE NEGATIVE REACTIONS; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; MALE; MICROSATELLITE REPEATS; PARENTS; POLYMORPHISM, GENETIC; SENSITIVITY AND SPECIFICITY;

EID: 0033954077     PISSN: 10889051     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. American Psychiatric Association. 1994. Diagnostic and statistical manual of mental disorders, 4th ed. American Psychiatric Association, Washington, DC.
2. Asherson, P., R. Mant, N. Williams, A. Cardno, L. Jones, K. Murphy, D.A. Collier, S. Nanko, N. Craddock, S. Morris et al. 1998. A study of chromosome 4p markers and dopamine D5 receptor gene in schizophrenia and bipolar disorder. Mol. Psychiatry 3: 310-320.
3. Barcellos, L.F., W. Klitz, L.L. Field, R. Tobias, A.M. Bowcock, R. Wilson, M.P. Nelson, J. Nagatomi, and G. Thomson. 1997. Association mapping of disease loci, by use of a pooled DNA genomic screen. Am. J. Hum. Genet. 61: 734-747.
4. Berrettini, W. 1998. Progress and pitfalls: Bipolar molecular linkage studies. J. Affect. Disord. 50: 287-297.
5. Blackwood, D.H.R., L. He, S.W. Morris, A. McLean, C. Whitton, M. Thomson, M.T. Walker, K. Woodburn, C.M. Sharp, A.F. Wright, Y. Shibasaki, D.M. St Clair, D.J. Porteous, and W.L. Muir. 1996. A locus for bipolar affective disorder on chromosome 4p. Nat. Genet. 12: 427-430.
6. Bowcock, A.M., M.A. Chipperfield, P. Ceverha, E. Yetman, and A. Phung. 1996. Report of the DNA committee. In Human Gene Mapping 1995: A compendium (eds. A.J. Cuticchia, M.A. Chipperfield, and P.A. Foster), pp. 1454-1468. John Hopkins University Press, Baltimore, MD.
7. Camp, N.J. 1997. Genomewide transmission/disequilibrium testing - Consideration of the genotypic relative risks at disease loci. Am. J. Hum. Genet. 61: 1424-1430.
8. _. 1999. Genomewide transmission/disequilibrium testing: A correction. Am. J. Hum. Genet. 64: 1485-1487.
9. Cargill, M., D. Altshuler, J. Ireland, P. Sklar, K. Ardlie, N. Patil, C.R. Lane, E.P. Lim, N. Kalayanaraman, J. Nemesh et al. 1999. Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nat. Genet. 22: 231-238.
10. Craddock, N., V. Khodel, P. Van Eerdewegh, and T. Reich. 1995. Mathematical limits of multilocus models: The genetic transmission of Bipolar disorder. Am. J. Hum. Genet. 57: 690-702.
11. Daniels, J., P. Holmans, N. Williams, D. Turk, P. McGuffin, R. Plomin, and M.J. Owen. 1998. A simple method for analysing microsatellite allele image patterns generated from DNA pools and its application to allelic association studies. Am. J. Hum. Genet. 62: 1189-1197.
12. Fisher, P.J., D. Turic, N.M. Williams, P. McGuffin, P. Asherson, D. Ball, I. Craig, T. Eley, L. Hill, K. Chorney, M.J. Chorney et al. 1999. DNA pooling identifies QTLs on chromosome 4 for general cognitive ability in children. Hum. Mol. Genet. 8: 915-922.
13. Ginns, E.I., P. St Jean, R.A. Philibert, M. Galdzicka, P. Damschroder-Williams, B. Thiel, R.T. Long, L.J. Ingraham, H. Dalwaldi, M.A. Murray et al. 1998. A genome-wide search for chromosomal loci linked to mental health wellness in relatives at high risk for bipolar affective disorder among the Old Order Amish. Proc. Natl. Acad. Sci. 22: 15531-15536.
14. Kendler, K.S., C.J. MacLean, Y. Ma, F.A. O'Neill, D. Walsh, and R.E. Straub. 1999. Marker-to-marker linkage disequilibrium on chromosomes Sq, 6p, and 8p in Irish high-density schizophrenia pedigrees. Am. J. Med. Genet. 88: 29-33.
15. Kruglyak, L. 1999. Prospects for whole-genome linkage disequilibrium mapping of common disease genes. Nat. Genet. 22: 139-144.
16. LeDuc, C., M.J. Lichter, and P. Parry. 1995. Batched analysis of genotypes. PCR Methods Applic. 4: 331-336.
17. Lipkin, E., M.O. Mosig, A. Darvasi, E. Ezra, A. Shalom, A. Friedmann, and M. Soller. 1988. Quantitative trait locus mapping in dairy cattle by means of selective milk DNA pooling using dinucleotide microsatellite markers: Analysis of milk protein percentage. Genetics 149: 1557-1567.
18. Lipshutz, R.J., S.P.A. Fodor, T.R. Gingeras, and D.J. Lockhart. 1999. High density synthetic oligonucleotide arrays. Nat. Genet. (Suppl.) 21: 20-24.
19. McGuffin, P., M.J. Owen, M.C. O'Donovan, A. Thapar, and I.I. Gottesman. 1994. Affective disorders (chapter 6). Seminars in psychiatric genetics, pp. 110-127. Royal College of Psychaitrists, London, UK.
20. Owen, M.J. and P. McGuffin. 1993. Association and linkage: Complementary strategies for complex disorders. J. Med. Genet. 30: 638-639.
21. Pacek, P., A. Sajantila, and A.-C. Syvänen. 1993 Determination of allele frequencies at loci with length polymorphism by quantitative analysis of DNA amplified from pooled samples. PCR Methods Applic. 2: 313-317.
22. Perlin, M.W., G. Lancia, and S.-K. Ng. 1995. Toward fully automated genotyping: Genotyping microsatellite markers by deconvolution. Am. J. Hum. Genet. 57: 1199-1210.
23. Risch, N. and K. Merikangas. 1996. The future of gentic studies of complex human diseases. Science 273: 1516-1517.
24. Risch, N. and J. Teng. 1998. The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases. I. DNA pooling. Genome Res. 8: 1273-1288.
25. Sham, P.C. and D. Curtis. 1995a. Monte Carlo test for association between disease and alleles at highly polymorphic loci. Ann. Hum. Genet. 59: 97-105.
26. _. 1995b. An extended transmission disequilibrium test (TDT) for multiallele marker loci. Ann. Hum. Genet. 59: 323-336.
27. Shaw, S.H., M.M. Carrasquillo, C. Kashuk, E.G. Puffenberger, and A. Chakravarti. 1998. Allele frequency distributions in pooled DNA samples: Applications to mapping complex disease genes. Genome Res. 8: 111-123.
28. Sheffield, V.C., M.E. Pierpont, D. Nishimura, J.S. Beck, T.L. Burns, M.A. Berg, E.M. Stone, S.R. Paul, and K.M. Lauer. 1997. Identification of a complex congenital heart defect susceptibility locus by using DNA pooling and shared segment analysis. Hum. Mol. Genet. 6: 117-121.
29. Spielman, R.S. and W.J. Ewens. 1996. The TDT and other family-based tests for linkage disequilibrium and association. Am. J. Hum. Genet. 59: 983-989.
30. Terwilliger, J.D. and J. Ott. 1992. A haplotype-based "haplotype relative risk" approach to detecting allelic associations. Hum. Hered. 42: 337-346.
31. Tsuang, M.T. and S.V. Faraone. 1990. The genetics of mood disorders. John Hopkins University Press, Baltimore, MD.
32. Wang, D.G., J.B. Fan, C.J. Siao, A. Berno, P. Young, R. Sapolsky, G. Ghandour, N. Perkins, E. Winchester, J. Spencer et al. 1998. Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. Science 280: 1077-1082.
33. Wing, J.K., T. Babor, T. Brugha, J. Burke, J.E. Cooper, R. Giel, A. Jablenski, D. Regier, and N. Sartorius. 1990. Schedules for clinical assessment in neuropsychiatry. Arch. Gen. Psychiatry. 47:137-144.