In silico-initiated cloning and molecular characterization of a novel human member of the L1 gene family of neural cell adhesion molecules

Human Genetics

Volumn 103, Issue 3, 1998, Pages 355-364

  Wei, Ming Hui ^a   Karavanova, Irina ^a   Ivanov, Sergey V ^a   Popescu, Nicolae C ^b   Keck, Catherine L ^b   Pack, Svetlana ^b   Eisen, Jonathan A ^c   Lerman, Michael I ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; NERVE CELL ADHESION MOLECULE;

ARTICLE; CENTRAL NERVOUS SYSTEM; DNA DETERMINATION; GENE EXPRESSION; HUMAN; IN SITU HYBRIDIZATION; MEMBRANE STRUCTURE; MENTAL DEFICIENCY; MOLECULAR CLONING; MULTIGENE FAMILY; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPINAL CORD; TUMOR CELL LINE;

AMINO ACID SEQUENCE; ANIMALS; CHROMOSOMES, HUMAN, PAIR 3; CLONING, MOLECULAR; GENETIC MARKERS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKOCYTE L1 ANTIGEN COMPLEX; MEMBRANE GLYCOPROTEINS; MENTAL RETARDATION; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEURAL CELL ADHESION MOLECULES; PHYLOGENY; RATS; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID;

MURINAE;

EID: 0031682085     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004390050829     Document Type: Article

References (37)

1. Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25:3389-3402
2. Altura RA, Maris JM, Li H, Boyett JM, Brodeur GM, Look T (1997) Novel regions of chromosomal loss in familial neuroblastoma by comparative genomic hybridization. Genes Chromosom Cancer 19:176-184
3. Asai M, Ito Y, Iguchi T, Ito J, Okada N, Oishi H (1992) Terminal deletion of the short arm of chromosome 3. Jpn J Hum Genet 37:163-168
4. Bateman A, Jouet M, MacFarlane J, Du J-S, Kenwrick S, Clothia C (1996) Outline structure of the human L1 cell adhesion molecule and the sites where mutations cause neurological disorders. EMBO J 15:6050-6059
5. Brummendorf T, Rathjen FG (1995) Cell adhesion molecules 1: immunoglobulin superfamily. Protein Profile 2:963-1108
6. Dahlin-Huppe K, Berglund EO, Ranscht B, Stallcup WB (1997) Mutational analysis of the L1 neuronal cell adhesion molecule identifies membrane-proximal amino acids of the cytoplasmic domain that are required for cytoskeletal anchorage. Mol Cell Neurosci 9:144-156
7. Dahme M, Bartsch U, Anliker B, Schachner M, Mantei N (1997) Disruption of the mouse L1 gene leads to malformations of the nervous system. Nat Genet 17:346-349
8. Davis JQ, Bennett V (1994) Ankirin binding activity shared by the neurofascin/L1/NrCAM family of nervous system cell adhesion molecules. J Biol Chem 269:27163-27166
9. Davis JQ, McLaughlin T, Bennett V (1993) Ankirin-binding proteins related to nervous system cell adhesion molecules: candidates to provide transmembrane and intercellular connections in adult brain. J Cell Biol 121:121-133
10. Deng G, Lu Y, Zlotnikov G, Thor AD, Smith HS (1996) Loss of heterozygosity in normal tissue adjacent to breast carcinomas. Science 274:2057-2059
11. Doherty P, Walsh FS (1996) CAM-FGF receptor interactions: a model for axonal growth. Mol Cell Neurosci 8:99-111
12. Dubreuil RR, MacVicar G, Dissanayake S, Liu C, Homer D, Hortsch M (1996) Neuroglian-mediated cell adhesion induces assembly on the membrane skeleton at cell contact sites. J Cell Biol 133:647-655
13. Eisen JA (1998) Phylogenomics: improving functional predictions for uncharacterized genes by evolutionary analysis. Genome Res 8:163-167
14. Fransen E, Vits L, Van Gamp G, Willems PJ (1996) CRASH syndrome: the clinical spectrum of mutations in L1, a neuronal cell adhesion molecule. Am J Med Genet 64:73-77
15. Goodman CS, Shatz CJ (1993) Developmental mechanisms that generate presize patterns of neuronal connectivity. Cell 72:77-98
16. Haas TA, Plow EF (1994) Integrin-ligand interactions: a year in review. Curr Opin Cell Biol 6:656-662
17. Holm J, Hillenbrand R, Steuber V, Bartsch U, Moos M, Lubbert H, Montag D, Schachner M (1996) Structural features of a close homologue of L1 (CHL1) in the mouse: a new member of the L1 family of neural recognition molecules. Eur J Neurosci 8:1613-1629
18. Hortsch M (1996) The L1 family of neural cell adhesion molecules: old proteins performing new tricks. Neuron 17:587-593
19. Kamiguchi H, Lemmon V (1997) Neural cell adhesion molecule L1: signaling pathways and growth cone motility. J Neurosci Res 49:1-8
20. Lerman MI, Latif F, Glenn GM, Daniel L, Brauch H, Hosoe S, Hampsch K, Delisio J, Orcutt ML, McBride OW, Grzeschik KH, Takahashi T, Minna J, Anglard P, Linehan WM, Zbar B (1991) Isolation and regional localization of a large collection (2000) of single copy DNA fragments on human chromosome 3 for mapping and cloning tumor suppressor genes. Hum Genet 86:567-577
21. Otsuka AJ, Franco R, Yang B, Shim KH, Tang LZ, Zhang YY, Boontrakulpoontawee P, Jeyaprakash A, Hedgecock E, Wheaton VI (1995) An ankirin-related gene (unc-44) is necessary for proper axonal guidance in Caenorhabditis elegans. J Cell Biol 129:1081-1092
22. Pack SD, Tanigami A, Ledbetter DH, Sato T, Fukuda MN (1997) Assignment of trophoblast/endometrial epithelium cell adhesion molecule trophinin gene TRO to human chromosome bands-Xp11.226p11.21 by in situ hybridization. Cytosenet Cell Genet 79:123-124
23. Plomin R, Craig I (1997) Human behavioral genetics of cognitive abilities and disabilities. Bioessays 19:1117-1124
24. Plomin R, McClearn GE, Smith DL, Vignetti S, Chorney MJ, Chorney K, Venditti CP, Kasarda S, Thompson LA, Detterman DK, Daniels J, Owen M, McGuffin P (1994a) DNA markers associated with high versus low IQ: the IQ quantitative trait loci (QTL) project. Behav Genet 24:107-118
25. Plomin R, Owen MJ, McGuffin P (1994b) The genetic basis of complex human behaviors. Science 264:1733-1739
26. Popescu NC, Zimonjic D, Hatch C, Bonner W (1994) Chromosomal mapping of the human histone gene H2AZ to 4q24 by fluorescence in situ hybridization. Genomics 20:333-335
27. Ranheim TS, Edelman GM, Cunningham BA (1996) Homophilic adhesion by the neural cell adhesion molecule involves multiple immunoglobulin domains. Proc Natl Acad Sci USA 93:4071-4075
28. Reichert H, Boyan G (1997) Building a brain: developmental insights in insects. Trends Neurosci 20:258-264
29. Sambrook Y, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
30. Schachner M (1997) Neural recognition molecules and synaptic plasticity. Curr Opin Cell Biol 9:627-634
31. Swofford DL (1993) Paup: a computer program for phylogenetic inference using maximum parsimony. J Gen Physiol 102:9A
32. Thompson JD, Higgins DG, Gibson TJ (1994) Clustal W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22:4673-4680
33. Vaughn DE, Bjorkman PJ (1996) The (Greek) key to structures of neural adhesion molecules, Neuron 16:261-273
34. Wahlstrom J (1990) Gene map of mental retardation. J Ment Defic Res 34:11-27
35. Wilkinson D, Green J (1990) In situ hybridization and the three-dimensional reconstruction of serial sections. In: Copp AJ, Cokroft (eds) Postimplantation mammalian embryos. Oxford University Press, London, pp 155-171
36. Wilson GN, Pooley J, Rarker J (1982) The phenotype of ring chromosome 3. J Med Genet 19:471-473
37. Zisch AH, Stallcup WB, Chong LD, Dahlin-Huppe K, Voshol J, Schachner M, Pasquale EB (1997) Tyrosine phosphorylation of L1 family adhesion molecules: implication of the Eph kinase CEK5. J Neurosci Res 47:655-665