Alternative splicing of human NrCAM in neural and nonneural tissues

Molecular and Cellular Neurosciences

Volumn 10, Issue 5-6, 1998, Pages 287-295

  Wang, Bo ^a   Williams, Hawys ^c   Du, Jian Sheng ^c   Terrett, Jonathan ^b   Kenwrick, Sue ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c NONE

Author keywords

7q, gene expression; Neural cell adhesion molecule; NrCAM

Indexed keywords

NERVE CELL ADHESION MOLECULE;

ADRENAL GLAND; ADULT; ALTERNATIVE RNA SPLICING; ARTICLE; BRAIN; CHROMOSOME 7Q; FETUS; GENE EXPRESSION; HUMAN; HUMAN TISSUE; NERVOUS TISSUE; NUCLEOTIDE SEQUENCE; PANCREAS; PLACENTA; PRIORITY JOURNAL; TISSUE DISTRIBUTION;

EID: 13144255754     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.1997.0658     Document Type: Article

References (32)

1. Achille, A., Biasi, M. O., Zamboni, G., Bogina, G., Magalini, A. R., Pederzoli, P., Perucho, M., and Scarpa, A. (1996). Chromosome 7q allelic losses in pancreatic carcinoma. Cancer Res. 56(16): 3808-3813.
2. Brummendorf, T., and Rathjen, F. G. (1993). Axonal glycoproteins with immunoglobulin- and fibronectin type III-related domains in vertebrates: Structural features, binding activities and signal transduction. J. Neurochem. 61:1207-1209.
3. Brummendorf, T., and Rathjen, F. G. (1996). Structure/function relationships of axon-associated adhesion receptors of the immunoglobulin superfamily. Curr. Opin. Neurol. 6:584-593.
4. Cho, K. R., and Fearon, E. R. (1995). DCC: Linking tumour suppressor genes and altered cell surface interaction in cancer. Eur. J. Cancer 31: 1055-1060.
5. Davis, J. K., and Bennett, V. (1994). Ankyrin binding activity shared by the neurofascin/L1/NrCam family of nervous system cell adhesion molecules. J. Biol. Chem. 269: 27163-27166.
6. Fink, J. M., Hirsch, B. A., Zheng, C., Dietz, G., Hatten, M. E., and Ross, M. E. (1997). Genomics. Genomics 40(1): 202-205.
7. Fransen, E., Vits, L., van Camp, G., and Willems, P. (1996). The clinical spectrum of mutations in L1, a neuronal cell adhesion molecule. Am. J. Med. Genet 64: 73-77.
8. Carver, T. D., Ren, Q., Tuvia, S., and Bennett, V. (1997). Tyrosine phosphorylation at a site highly conserved in the L1 family of cell adhesion molecules abolishes ankyrin binding and increases lateral mobility of neurofascin. J. Cell Biol. 137(3): 703-714.
9. GilNagel, A., Dubovsky J., Wilcox, K. J., Stewart, J. M., Anderson, V. E., Leppik, I. E., Orr, H. T., Johnson, E. W., Weber, J. L., and Rich, S. S. (1996). Familial cerebral cavernous angioma: A gene localized to a 15-cm interval on chromosome 7q. Ann. Neurol. 39(6): 807-810.
10. Grumet, M. (1991). Cell adhesion molecules and their subgroups in the nervous system. Current Op. Neurobiol. 1:370-376.
11. Grumet, M., Mauro, V., Burgoon, M. P., Edelman, G. M., and Cunningham, B. A. (1991). Structure of a new nervous system glycoprotein, NrCAM, and its relationship to subgroups of neural cell adhesion molecules. J. Cell Biol. 113(6): 1399-1412.
12. Jouet, M., Rosenthal, A., and Kenwrick, S. (1995). Exon 2 of the gene for neural cell adhesion molecule L1 is alternatively spliced in B cells. Mol. Brain Res. 30:378-380.
13. Kayyem, J. E, Roman, J. M., de la Rosa, E. J., Schwarz, U., and Dreyer, W. J. (1992). Bravo/NrCAM is closely related to the cell adhesion molecules L1 and NgCAM and has a similar heterodimer structure. J. Cell Biol. 118(5): 1259-1270.
14. Kenwrick, S., Jouet, M., and Donnai, D. (1996). X-linked hydrocephalus and MASA syndrome. J. Med. Genet. 33: 59-65.
15. Kerr, J., Leary, J. A., Hurst, T., Shih, Y.-C., Antalis, T. M., Friedlander, M., Crawford, E., Khoo, S. K., Ward, B., and Chenevix-Trench, G. (1996). Allelic loss an chromosome 7q in ovarian adenocarcinomas: Two critical regions and a rearrangement of the PLANH1 locus. Oncogene 13: 1815-1818.
16. Lane, R. B., Chen, X.-N., Yamakawa, K., Vielmetter, J., Korenberg, J. R., and Dreyer, W. J. (1996). Characterisation of a highly conserved human homolog to the chicken neural cell surface protein Bravo/NrCAM that maps to chromosome band 7q31. Genomics 35: 456-465.
17. Lin, J. C., Scherer, S. W., Tougas, L., Traverso, G., Tsui, L.-C., Andrulis, I. L., Jothy, S., and Park, M. (1996). Detailed deletion mapping with a refined physical map of 7q31 localizes a putative tumor suppressor gene for breast cancer in the region of MET. Oncogene 13: 2001-2008.
18. Mauro, V. P., Krushel, L. A., Cunningham, B. A., and Edelman, G. M. (1992). Homophilic and heterophilic binding activities of NrCAM, a nervous system cell adhesion molecule. J. Cell Biol. 119(1): 191-202.
19. Morales, G., Hubert, M., Brummendorf, T., Treubert, U., Tarnok, A., Schwarz, U., and Rathjen, F. G. (1993). Induction of axonal growth by heterophilic interaction between the cell surface recognition proteins F11 and NrCAM/Bravo. Neuron 11: 1113-1122.
20. Moscoso, L. M., and Sanes, J. R. (1995). Expression of four immunoglobulin superfamily adhesion molecules (L1, NrCAM/Bravo, neurofascin/ABGP, and NCAM) in the developing mouse spinal cord. J. Comp. Neurol. 352: 321-334.
21. Nybroe, O., Linnemann, D., and Bock, E. (1988). NCAM biosynthesis in brain. Neurochem. Int. 12: 251-262.
22. Pandya, A., Blanton, S. H., Landa, B., Javaheri, R., Melvin, E., Nance, W. E., and Markello, T. (1996). Linkage studies in a large kindred with hereditary pancreatitis confirms mapping of the gene to a 16-cM region on 7q. Genomics 38: 227-230.
23. Reid, R. A., and Hemperley, J. J. (1992). Variants of human L1 cell adhesion molecule arise through alternate splicing of RNA. J. Mol. Neurosci. 3: 127-135.
24. SolinasToldo, S., Wallrapp, C., MullerPillasch, E, Bentz, M., Gress, T., and Lichter, P. (1996). Mapping of chromosomal imbalances in pancreatic carcinoma by comparative genomic hybridization. Cancer Res. 56(16): 3803-3907.
25. Stoeckli, E., and Landmesser, L. T. (1995). Axonin-1, NrCAM and NgCAM play different roles in the in vivo guidance of chick commissural neurons. Neuron 14:1165-1179.
26. Suter, D. M., Pollerberg, G. E., Buchstaller, A., Giger, R. J., Dreyer, W. J., and Sonderegger, P. (1995). Binding between the neural cell adhesion molecules axonin-1 and NrCAM/Bravo is involved in neuronglia interaction. J. Cell Biol. 131(4): 1067-1081.
27. Tsui, I-C., Donis-keller, H., and Grzeschik, K.-H. (1995). Report of the second international workshop on human chromosome 7 mapping 1994. Cytogenet. Cell Genet. 71:2-21.
28. Volkmer, H., Hassel, B., Wolff, J. M., Frank, R., and Rathjen, F. G. (1992). Structure of the axonal surface recognition molecule neurofascin and its relationship to a neural subgroup of the immunoglobulin superfamily. J. Cell Biol. 118:149-161.
29. Volkmer, H., Leuschner, R., Zacharias, U., and Rathjen, F. G. (1996). Neurofascin induces neuntes by heterophilic interactions with axonal NrCAM while NrCAM requires F11 on the axonal surface to extend neurites. J. Cell Biol. 135(4): 1059-1069.
30. Walsh, F. S., and Doherty P. (1991). Structure and function of the gene for neural cell adhesion molecule. Semin. Neurosci. 3: 271-284.
31. Weber, R. G., Sabel, M., Reifenberger, J., Sommer, C., Oberstrab, J., Reifenberger, G., Kiessling, M., and Cremer, T. (1996). Characterization of genomic alterations associated with glioma progression by comparative genomic hybridization. Oncogene 13: 983-994.
32. Wong, E. V., Schaefer, A. W., Landreth, G., and Lemmon, V. (1996). Casein kinase II phosphorylates the neural cell adhesion molecule L1. J. Neurochem. 66(2): 779-786.