메뉴 건너뛰기




Volumn 278, Issue 6 SUPPL. 1, 2000, Pages

Human Caco-2 motility redistributes FAK and paxillin and activates p38 MAPK in a matrix-dependent manner

Author keywords

Epithelium; Focal adhesion kinase; Intestine; Migration; Mitogen activated protein kinase; Restitution; Signal transduction

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; FOCAL ADHESION KINASE; MATRIX PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PAXILLIN; SYNAPTOPHYSIN;

EID: 0033947162     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.2000.278.6.g952     Document Type: Article
Times cited : (62)

References (54)
  • 1
    • 0033000286 scopus 로고    scopus 로고
    • Integrin and cytoskeletal regulation of growth factor signaling to the MAP kinase pathway
    • Aplin AE and Juliano RL. Integrin and cytoskeletal regulation of growth factor signaling to the MAP kinase pathway. J Cell Sci 112: 695-706, 1999.
    • (1999) J Cell Sci , vol.112 , pp. 695-706
    • Aplin, A.E.1    Juliano, R.L.2
  • 2
    • 0031955649 scopus 로고    scopus 로고
    • Role of integrins in enterocyte migration
    • Basson MD. Role of integrins in enterocyte migration. Clin Exp Pharmacol Physiol 25: 280-285, 1998.
    • (1998) Clin Exp Pharmacol Physiol , vol.25 , pp. 280-285
    • Basson, M.D.1
  • 3
    • 0029781237 scopus 로고    scopus 로고
    • Amplitude-dependent modulation of brush border enzymes and proliferation by cyclic strain in human intestinal Caco-2 monolayers
    • Basson MD, Li GD, Hong F, Han O, and Sumpio BE. Amplitude-dependent modulation of brush border enzymes and proliferation by cyclic strain in human intestinal Caco-2 monolayers. J Cell Physiol 168: 476-488, 1996.
    • (1996) J Cell Physiol , vol.168 , pp. 476-488
    • Basson, M.D.1    Li, G.D.2    Hong, F.3    Han, O.4    Sumpio, B.E.5
  • 4
    • 0026629491 scopus 로고
    • Human enterocyte (Caco-2) migration is modulated in vitro by extracellular matrix composition and epidermal growth factor
    • Basson MD, Modlin IM, and Madri JA. Human enterocyte (Caco-2) migration is modulated in vitro by extracellular matrix composition and epidermal growth factor. J Clin Invest 90: 15-23, 1992.
    • (1992) J Clin Invest , vol.90 , pp. 15-23
    • Basson, M.D.1    Modlin, I.M.2    Madri, J.A.3
  • 5
    • 0029899741 scopus 로고    scopus 로고
    • Regulation of human (Caco-2) intestinal epithelial differentiation by extracellular matrix proteins
    • Basson MD, Turowski G, and Emenaker NJ. Regulation of human (Caco-2) intestinal epithelial differentiation by extracellular matrix proteins. Exp Cell Res 225: 301-305, 1996.
    • (1996) Exp Cell Res , vol.225 , pp. 301-305
    • Basson, M.D.1    Turowski, G.2    Emenaker, N.J.3
  • 6
    • 0032488827 scopus 로고    scopus 로고
    • Cell density modulates protein-tyrosine phosphorylation
    • Batt D and Roberts T. Cell density modulates protein-tyrosine phosphorylation. J Biol Chem 273: 23408-23414, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 23408-23414
    • Batt, D.1    Roberts, T.2
  • 8
    • 0026445719 scopus 로고
    • Tyrosine phosphorylation of paxillin and p125 FAK accompanies cell adhesion to extracellular matrix: A role in cytoskeletal assembly
    • Burridge K, Turner CE, and Romer LH. Tyrosine phosphorylation of paxillin and p125 FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly. J Cell Biol 119: 893-903, 1992.
    • (1992) J Cell Biol , vol.119 , pp. 893-903
    • Burridge, K.1    Turner, C.E.2    Romer, L.H.3
  • 9
    • 0028926263 scopus 로고
    • Parallel signal processing among mammalian MAPKs
    • Cano E and Mahadevan LC. Parallel signal processing among mammalian MAPKs. Trends Biochem Sci 20: 117-122, 1995.
    • (1995) Trends Biochem Sci , vol.20 , pp. 117-122
    • Cano, E.1    Mahadevan, L.C.2
  • 10
    • 0028987936 scopus 로고
    • Integrins and signal transduction pathways: The road taken
    • Clark EA and Brugge JS. Integrins and signal transduction pathways: the road taken. Science 268: 233-239, 1995.
    • (1995) Science , vol.268 , pp. 233-239
    • Clark, E.A.1    Brugge, J.S.2
  • 12
    • 0031575908 scopus 로고    scopus 로고
    • ERK and p38 MAP kinase pathways are mediators of intestinal epithelial wound-induced signal transduction
    • Dieckgraefe BK, Weems DM, Santoro SA, and Alpers DH. ERK and p38 MAP kinase pathways are mediators of intestinal epithelial wound-induced signal transduction. Biochem Biophys Res Commun 233: 389-394, 1997.
    • (1997) Biochem Biophys Res Commun , vol.233 , pp. 389-394
    • Dieckgraefe, B.K.1    Weems, D.M.2    Santoro, S.A.3    Alpers, D.H.4
  • 13
    • 0026020583 scopus 로고
    • Receptor functions for the integrin VLA-3: Fibronectin, collagen, and laminin binding are differentially influenced by Arg-Gly-Asp peptide and by divalent cations
    • Elices MM, Urry LA, and Hemler MH. Receptor functions for the integrin VLA-3: fibronectin, collagen, and laminin binding are differentially influenced by Arg-Gly-Asp peptide and by divalent cations. J Cell Biol 112: 169-181, 1991.
    • (1991) J Cell Biol , vol.112 , pp. 169-181
    • Elices, M.M.1    Urry, L.A.2    Hemler, M.H.3
  • 14
    • 0028018234 scopus 로고
    • Potential role for focal adhesion kinase in migrating and proliferating keratinocytes near epithelial wounds and in culture
    • Gates RE, King LK Jr, Hanks SK, and Nanney LB. Potential role for focal adhesion kinase in migrating and proliferating keratinocytes near epithelial wounds and in culture. Cell Growth Differ 5: 891-899, 1994.
    • (1994) Cell Growth Differ , vol.5 , pp. 891-899
    • Gates, R.E.1    King Jr., L.K.2    Hanks, S.K.3    Nanney, L.B.4
  • 15
    • 0029741102 scopus 로고    scopus 로고
    • Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation
    • Gilmore AP and Romer LH. Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation. Mol Biol Cell 7: 1209-1224, 1996.
    • (1996) Mol Biol Cell , vol.7 , pp. 1209-1224
    • Gilmore, A.P.1    Romer, L.H.2
  • 16
    • 0031921299 scopus 로고    scopus 로고
    • Rapid mitogen-activated protein kinase activation by transforming growth factor alpha in the wounded rat intestinal epithelial cells
    • Goke M, Kanai M, Lynch-Devaney K, and Podolsky DK. Rapid mitogen-activated protein kinase activation by transforming growth factor alpha in the wounded rat intestinal epithelial cells. Gastroenterology 114: 697-705, 1998.
    • (1998) Gastroenterology , vol.114 , pp. 697-705
    • Goke, M.1    Kanai, M.2    Lynch-Devaney, K.3    Podolsky, D.K.4
  • 17
    • 0031706278 scopus 로고    scopus 로고
    • Strain induces Caco-2 intestinal epithelial proliferation and differentiation via PKC and tyrosine kinase signals
    • Han O, Li GD, Sumpio BE, and Basson MD. Strain induces Caco-2 intestinal epithelial proliferation and differentiation via PKC and tyrosine kinase signals. Am J Physiol Gastrointest Liver Physiol 275: G534-G541, 1998.
    • (1998) Am J Physiol Gastrointest Liver Physiol , vol.275
    • Han, O.1    Li, G.D.2    Sumpio, B.E.3    Basson, M.D.4
  • 18
    • 0008490902 scopus 로고    scopus 로고
    • Biological roles of the non-integrin elastin/laminin receptor
    • Hinek A. Biological roles of the non-integrin elastin/laminin receptor. Biol Chem 377: 471-480, 1996.
    • (1996) Biol Chem , vol.377 , pp. 471-480
    • Hinek, A.1
  • 19
    • 0026244776 scopus 로고
    • Caco-2 cells cultured in a serum free medium as a model for the study of enterocytic differentiation in vitro
    • Jumarie C and Malo C. Caco-2 cells cultured in a serum free medium as a model for the study of enterocytic differentiation in vitro. J Cell Physiol 149: 24-33, 1992.
    • (1992) J Cell Physiol , vol.149 , pp. 24-33
    • Jumarie, C.1    Malo, C.2
  • 20
    • 0033522510 scopus 로고    scopus 로고
    • Src family kinases are required for integrin but not PDGFR signal transduction
    • Klinghoffer RA, Sachsenmaier C, Cooper JA, and Soriano P. Src family kinases are required for integrin but not PDGFR signal transduction. EMBO J 18: 2459-2471, 1999.
    • (1999) EMBO J , vol.18 , pp. 2459-2471
    • Klinghoffer, R.A.1    Sachsenmaier, C.2    Cooper, J.A.3    Soriano, P.4
  • 21
    • 0029912152 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor-1 stimulate dephosphorylation of paxillin in parallel with focal adhesion kinase
    • Konstantopoulos N and Clark S. Insulin and insulin-like growth factor-1 stimulate dephosphorylation of paxillin in parallel with focal adhesion kinase. Biochem J 314: 387-390, 1996.
    • (1996) Biochem J , vol.314 , pp. 387-390
    • Konstantopoulos, N.1    Clark, S.2
  • 22
    • 0025979573 scopus 로고
    • Expression of VLA-α2, VLA-α6, and VLA-β1 chains in normal mucosa and adenomas of the colon and in colon carcinomas and liver metastases
    • Koretz K, Schlag P, Boumsell L, and Moller P. Expression of VLA-α2, VLA-α6, and VLA-β1 chains in normal mucosa and adenomas of the colon and in colon carcinomas and liver metastases. Am J Pathol 138: 741-750, 1991.
    • (1991) Am J Pathol , vol.138 , pp. 741-750
    • Koretz, K.1    Schlag, P.2    Boumsell, L.3    Moller, P.4
  • 24
    • 0031050651 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of paxillin and focal adhesion kinase during insulin-like growth factor-I-stimulated lamelipodial advance
    • Leventhal PS, Shelden EA, Kim B, and Feldman EL. Tyrosine phosphorylation of paxillin and focal adhesion kinase during insulin-like growth factor-I-stimulated lamelipodial advance. J Biol Chem 272: 5214-5218, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 5214-5218
    • Leventhal, P.S.1    Shelden, E.A.2    Kim, B.3    Feldman, E.L.4
  • 25
    • 0031740326 scopus 로고    scopus 로고
    • Enterocytic differentiation of the human Caco-2 cell line correlates with alterations in integrin signaling
    • Levy P, Robin H, Kornprobst M, Capeau J, and Cherqui G. Enterocytic differentiation of the human Caco-2 cell line correlates with alterations in integrin signaling. J Cell Physiol 177: 618-627, 1998.
    • (1998) J Cell Physiol , vol.177 , pp. 618-627
    • Levy, P.1    Robin, H.2    Kornprobst, M.3    Capeau, J.4    Cherqui, G.5
  • 26
    • 0030874021 scopus 로고    scopus 로고
    • Integrin-mediated activation of MAP kinase is independent of FAK: Evidence for dual integrin signaling pathways in fibroblasts
    • Lin TH, Aplin AE, Shen Y, Chen Q, Schaller M, Romer L, Aukhil I, and Juliano RL. Integrin-mediated activation of MAP kinase is independent of FAK: evidence for dual integrin signaling pathways in fibroblasts. J Cell Biol 136: 1385-1395, 1997.
    • (1997) J Cell Biol , vol.136 , pp. 1385-1395
    • Lin, T.H.1    Aplin, A.E.2    Shen, Y.3    Chen, Q.4    Schaller, M.5    Romer, L.6    Aukhil, I.7    Juliano, R.L.8
  • 27
    • 0032056569 scopus 로고    scopus 로고
    • Perspective article: Collagen expression by novel cell populations in the dermal wound environment
    • Lindblad WJ. Perspective article: collagen expression by novel cell populations in the dermal wound environment. Wound Repair Regen 6: 186-193, 1998.
    • (1998) Wound Repair Regen , vol.6 , pp. 186-193
    • Lindblad, W.J.1
  • 28
    • 0344505251 scopus 로고    scopus 로고
    • Human Caco-2 intestinal epithelia motility is associated with tyrosine kinase and cytoskeletal focal adhesion kinase signals
    • Liu Y-W, Sanders MA, and Basson MD. Human Caco-2 intestinal epithelia motility is associated with tyrosine kinase and cytoskeletal focal adhesion kinase signals. J Surg Res 77: 112-118, 1998.
    • (1998) J Surg Res , vol.77 , pp. 112-118
    • Liu, Y.-W.1    Sanders, M.A.2    Basson, M.D.3
  • 29
    • 0032600225 scopus 로고    scopus 로고
    • Loss of matrix-dependent cytoskeletal tyrosine kinase signals may regulate intestinal epithelial differentiation during mucosal healing
    • Liu Y-W, Sanders MA, and Basson MD. Loss of matrix-dependent cytoskeletal tyrosine kinase signals may regulate intestinal epithelial differentiation during mucosal healing. J Gastrointest Surg 3: 82-94, 1999.
    • (1999) J Gastrointest Surg , vol.3 , pp. 82-94
    • Liu, Y.-W.1    Sanders, M.A.2    Basson, M.D.3
  • 30
    • 0345561541 scopus 로고    scopus 로고
    • The 67 kDa laminin receptor as a prognostic factor in human cancer
    • Menard S, Tagliabue E, and Colnaghi MI. The 67 kDa laminin receptor as a prognostic factor in human cancer. Breast Cancer Res Treat 52: 137-145, 1998.
    • (1998) Breast Cancer Res Treat , vol.52 , pp. 137-145
    • Menard, S.1    Tagliabue, E.2    Colnaghi, M.I.3
  • 31
    • 0033002997 scopus 로고    scopus 로고
    • Induced focal adhesion (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- And activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2
    • Owen JD, Ruest PJ, Fry DW, and Hanks SK. Induced focal adhesion (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2. Mol Cell Biol 19: 4806-4818, 1999.
    • (1999) Mol Cell Biol , vol.19 , pp. 4806-4818
    • Owen, J.D.1    Ruest, P.J.2    Fry, D.W.3    Hanks, S.K.4
  • 32
    • 0031898865 scopus 로고    scopus 로고
    • Induction of mitogen-activated protein kinase signal transduction pathway during gastric ulcer healing in rats
    • Pai R, Ohta M, Itani RM, Sarfeh IJ, and Tarnawski A. Induction of mitogen-activated protein kinase signal transduction pathway during gastric ulcer healing in rats. Gastroenterology 114: 706-713, 1998.
    • (1998) Gastroenterology , vol.114 , pp. 706-713
    • Pai, R.1    Ohta, M.2    Itani, R.M.3    Sarfeh, I.J.4    Tarnawski, A.5
  • 33
    • 0031880834 scopus 로고    scopus 로고
    • Interleukin-6 production in human intestinal epithelial cells increases in association with the heat shock response
    • Parikh AA, Moon MR, Kane CD, Salzman AL, Fischer JE, and Hasselgren PO. Interleukin-6 production in human intestinal epithelial cells increases in association with the heat shock response. J Surg Res 77: 40-44, 1998.
    • (1998) J Surg Res , vol.77 , pp. 40-44
    • Parikh, A.A.1    Moon, M.R.2    Kane, C.D.3    Salzman, A.L.4    Fischer, J.E.5    Hasselgren, P.O.6
  • 34
    • 0031852687 scopus 로고    scopus 로고
    • Differential effects of mucosal pH on human (Caco-2) intestinal epithelial cell motility, proliferation, and differentiation
    • Perdikis DA, Davies R, Zhuravkov A, Brenner B, Etter L, and Basson MD. Differential effects of mucosal pH on human (Caco-2) intestinal epithelial cell motility, proliferation, and differentiation. Dig Dis Sci 43: 1537-1546, 1998.
    • (1998) Dig Dis Sci , vol.43 , pp. 1537-1546
    • Perdikis, D.A.1    Davies, R.2    Zhuravkov, A.3    Brenner, B.4    Etter, L.5    Basson, M.D.6
  • 35
    • 0028940917 scopus 로고
    • Cell density-dependent regulation of PLC gamma 1 tyrosine phosphorylation and catalytic activity in an intestinal cell line (IEC-6)
    • Polk DB, McCollum GW, and Carpenter G. Cell density-dependent regulation of PLC gamma 1 tyrosine phosphorylation and catalytic activity in an intestinal cell line (IEC-6). J Cell Physiol 162: 427-433, 1995.
    • (1995) J Cell Physiol , vol.162 , pp. 427-433
    • Polk, D.B.1    McCollum, G.W.2    Carpenter, G.3
  • 36
    • 0028218727 scopus 로고
    • Differential detergent fractionation of isolated hepatocytes: Biochemical, immunochemical and two-dimensional gel electrophoresis characterization of cytoskeletal and noncytoskeletal compartments
    • Ramsby ML, Makowski GS, and Khairallah EA. Differential detergent fractionation of isolated hepatocytes: biochemical, immunochemical and two-dimensional gel electrophoresis characterization of cytoskeletal and noncytoskeletal compartments. Electrophoresis 15: 265-277, 1994.
    • (1994) Electrophoresis , vol.15 , pp. 265-277
    • Ramsby, M.L.1    Makowski, G.S.2    Khairallah, E.A.3
  • 37
    • 0033113378 scopus 로고    scopus 로고
    • Raf-1 causes growth suppression and alteration of neuroendocrine markers in DMS53 human small-cell lung cancer cells
    • Ravi RK, Thiagalingam A, Weber E, McMahon M, Nelkin BD, and Mabry M. Raf-1 causes growth suppression and alteration of neuroendocrine markers in DMS53 human small-cell lung cancer cells. Am J Respir Cell Mol Biol 20: 543-549, 1999.
    • (1999) Am J Respir Cell Mol Biol , vol.20 , pp. 543-549
    • Ravi, R.K.1    Thiagalingam, A.2    Weber, E.3    McMahon, M.4    Nelkin, B.D.5    Mabry, M.6
  • 38
    • 0030694182 scopus 로고    scopus 로고
    • Inhibition of cell spreading by expression of C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: A role for paxillin tyrosine phosphorylation
    • Richardson A, Malik RK, Hildebrand JD, and Parson JT. Inhibition of cell spreading by expression of C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation. Mol Biol Cell 17: 6906-6914, 1997.
    • (1997) Mol Biol Cell , vol.17 , pp. 6906-6914
    • Richardson, A.1    Malik, R.K.2    Hildebrand, J.D.3    Parson, J.T.4
  • 39
    • 0028331263 scopus 로고
    • Tyrosine kinase activity, cytoskeleton organization, and motility in human vascular endothelial cells
    • Romer LH, Mclean N, Turner CE, and Burridge K. Tyrosine kinase activity, cytoskeleton organization, and motility in human vascular endothelial cells. Mol Biol Cell 5: 349-361, 1994.
    • (1994) Mol Biol Cell , vol.5 , pp. 349-361
    • Romer, L.H.1    Mclean, N.2    Turner, C.E.3    Burridge, K.4
  • 40
    • 4243376636 scopus 로고    scopus 로고
    • Wound matrix protein may regulate mucosal biology during restitution via P42 and P44 MAPK
    • Sanders MA and Basson MD. Wound matrix protein may regulate mucosal biology during restitution via P42 and P44 MAPK (Abstract). Gastroenterology 116: G1311, 1999.
    • (1999) Gastroenterology , vol.116
    • Sanders, M.A.1    Basson, M.D.2
  • 41
    • 0013635496 scopus 로고    scopus 로고
    • β1 integrin receptor binding may stimulate Caco-2 cell proliferation and differentiation via intracellular tyrosine phosphorylation and paxillin translocation
    • Sanders MA, Liu Y-W, and Basson MD. β1 integrin receptor binding may stimulate Caco-2 cell proliferation and differentiation via intracellular tyrosine phosphorylation and paxillin translocation. Surg Forum 48: 235-237, 1997.
    • (1997) Surg Forum , vol.48 , pp. 235-237
    • Sanders, M.A.1    Liu, Y.-W.2    Basson, M.D.3
  • 43
    • 0028609382 scopus 로고
    • Integrin-mediated signal transduction linked to ras pathway by Grb2 binding to focal adhesion kinase
    • Schlaepfer DD, Hanks SK, Hunter TT, and van der Geer P. Integrin-mediated signal transduction linked to ras pathway by Grb2 binding to focal adhesion kinase. Nature 372: 786-791, 1994.
    • (1994) Nature , vol.372 , pp. 786-791
    • Schlaepfer, D.D.1    Hanks, S.K.2    Hunter, T.T.3    Van Der Geer, P.4
  • 45
    • 0032820782 scopus 로고    scopus 로고
    • Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration
    • Seig DJ, Hauck CR, and Schlaepfer DD. Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration. J Cell Sci 112: 2677-2691, 1999.
    • (1999) J Cell Sci , vol.112 , pp. 2677-2691
    • Seig, D.J.1    Hauck, C.R.2    Schlaepfer, D.D.3
  • 46
    • 0033597343 scopus 로고    scopus 로고
    • Adhesion of cultured bovine aortic endothelial cells to laminin-1 mediated by dystroglycan
    • Shimizu H, Hosokawa H, Ninomiya H, Miner JH, and Masaki T. Adhesion of cultured bovine aortic endothelial cells to laminin-1 mediated by dystroglycan. J Biol Chem 274: 11995-12000, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 11995-12000
    • Shimizu, H.1    Hosokawa, H.2    Ninomiya, H.3    Miner, J.H.4    Masaki, T.5
  • 47
    • 0030793616 scopus 로고    scopus 로고
    • Effect of hypoxic hypoxia on transmural gut and subcutaneous tissue oxygen tension
    • Suski MD, Zabel D, Levin V, Scheuenstuhl H, and Hunt TK. Effect of hypoxic hypoxia on transmural gut and subcutaneous tissue oxygen tension. Adv Exp Med Biol 411: 319-322, 1997.
    • (1997) Adv Exp Med Biol , vol.411 , pp. 319-322
    • Suski, M.D.1    Zabel, D.2    Levin, V.3    Scheuenstuhl, H.4    Hunt, T.K.5
  • 48
    • 0028980418 scopus 로고
    • Direct association of pp125FAK with paxillin, the focal adhesion-targeting mechanism of pp125FAK
    • Tachibana K, Sato T, Avirro ND, and Morimoto C. Direct association of pp125FAK with paxillin, the focal adhesion-targeting mechanism of pp125FAK. J Exp Med 182: 1089-2000, 1995.
    • (1995) J Exp Med , vol.182 , pp. 1089-2000
    • Tachibana, K.1    Sato, T.2    Avirro, N.D.3    Morimoto, C.4
  • 49
    • 0032895264 scopus 로고    scopus 로고
    • Mechanosensitive tyrosine phosphorylation of paxillin and focal adhesion kinase in tracheal smooth muscle
    • Tang D, Mehta D, and Gunst SJ. Mechanosensitive tyrosine phosphorylation of paxillin and focal adhesion kinase in tracheal smooth muscle. Am J Physiol Cell Physiol 276: C250-C258, 1999.
    • (1999) Am J Physiol Cell Physiol , vol.276
    • Tang, D.1    Mehta, D.2    Gunst, S.J.3
  • 50
    • 0006762316 scopus 로고
    • Paxillin: A new vinculin-binding protein present in focal adhesion
    • Turner CE, Glenney JR, and Burridge K. Paxillin: a new vinculin-binding protein present in focal adhesion. J Cell Biol 108: 2401-2408, 1990.
    • (1990) J Cell Biol , vol.108 , pp. 2401-2408
    • Turner, C.E.1    Glenney, J.R.2    Burridge, K.3
  • 51
    • 0027968054 scopus 로고
    • Glutamine modulates phenotype and stimulates proliferation in human colon cancer cell lines
    • Turowski GA, Rashid Z, Hong F, Madri JA, and Basson MD. Glutamine modulates phenotype and stimulates proliferation in human colon cancer cell lines. Cancer Res 54: 5974-5980, 1994.
    • (1994) Cancer Res , vol.54 , pp. 5974-5980
    • Turowski, G.A.1    Rashid, Z.2    Hong, F.3    Madri, J.A.4    Basson, M.D.5
  • 52
    • 0028186644 scopus 로고
    • The bicinchoninic acid (BCA) assay for protein quantitation
    • Walker JM. The bicinchoninic acid (BCA) assay for protein quantitation. Methods Mol Biol 32: 5-8, 1994.
    • (1994) Methods Mol Biol , vol.32 , pp. 5-8
    • Walker, J.M.1
  • 53
    • 0029992274 scopus 로고    scopus 로고
    • Epithelial-matrix interaction: Laminin downregulates enterocyte EGF receptor and IGF-I receptor expression
    • Wolpert SI, Wong MD, Wang JY, and Bass BL. Epithelial-matrix interaction: laminin downregulates enterocyte EGF receptor and IGF-I receptor expression. J Surg Res 63: 345-348, 1996.
    • (1996) J Surg Res , vol.63 , pp. 345-348
    • Wolpert, S.I.1    Wong, M.D.2    Wang, J.Y.3    Bass, B.L.4
  • 54
    • 0028904784 scopus 로고
    • Integrin-dependent activation of MAP kinase: A link to shape-dependent cell proliferation. Mol Biol
    • Zhu X and Assoian RK. Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation. Mol Biol Cell 6: 273-282, 1995.
    • (1995) Cell , vol.6 , pp. 273-282
    • Zhu, X.1    Assoian, R.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.