메뉴 건너뛰기




Volumn 21, Issue 7, 2000, Pages 587-590

Contribution of genetic variations in estradiol biosynthesis and metabolism enzymes to osteoporosis

Author keywords

17beta HSD; CYP19; CYP1A2; CYP3A4; Estradiol; Osteoporosis

Indexed keywords

CYTOCHROME P450 3A4; ESTRADIOL; PRASTERONE;

EID: 0033942732     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (7)

References (25)
  • 3
    • 0031792594 scopus 로고    scopus 로고
    • Multiple splicing events involved in regulation of human aromatase expression by a novel promoter 1.6
    • Shozu M, Zhao Y, Bulun SE, Simpson ER. Multiple splicing events involved in regulation of human aromatase expression by a novel promoter 1.6. Endocrinology 1998; 139: 1610-7.
    • (1998) Endocrinology , vol.139 , pp. 1610-1617
    • Shozu, M.1    Zhao, Y.2    Bulun, S.E.3    Simpson, E.R.4
  • 4
    • 0028792229 scopus 로고
    • Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens
    • Morishima A, Grumbach MM, Simpson ER, Fisher C, Qin K. Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens. J Clin Endocrinol Metab 1995; 80: 3689-98.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 3689-3698
    • Morishima, A.1    Grumbach, M.M.2    Simpson, E.R.3    Fisher, C.4    Qin, K.5
  • 5
    • 15144341064 scopus 로고    scopus 로고
    • The aromatase excess syndrome is associated with feminization of both sexes and autosomal dominant transmission of aberrant P450 aromatase gene transcription
    • Stratakis CA, Vottero A, Brodie A, Kirschner LS, DeAtkine D, Lu Q, et al. The aromatase excess syndrome is associated with feminization of both sexes and autosomal dominant transmission of aberrant P450 aromatase gene transcription. J Clin Endocrinol Metab 1998; 83: 1348-57.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1348-1357
    • Stratakis, C.A.1    Vottero, A.2    Brodie, A.3    Kirschner, L.S.4    DeAtkine, D.5    Lu, Q.6
  • 8
    • 0027225486 scopus 로고
    • Expression cloning and characterization of human 17-β-hdroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20α-hydroxysteriod dehydrogenase activity
    • Wu L, Einstein M, Geissler WM, Chan HK, Elliston KO, Andersson S. Expression cloning and characterization of human 17-β-hdroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20α-hydroxysteriod dehydrogenase activity. J Biol Chem 1993; 268: 12961-9.
    • (1993) J Biol Chem , vol.268 , pp. 12961-12969
    • Wu, L.1    Einstein, M.2    Geissler, W.M.3    Chan, H.K.4    Elliston, K.O.5    Andersson, S.6
  • 9
    • 0027930787 scopus 로고
    • Male pseudohermaphroditism cause by mutation of testicular 17-β-hdroxysteroid dehydrogenase 3
    • Geissler WM, Davis DL, Wu L, Bradshaw KD, Patel S, Mendonca BB, et al. Male pseudohermaphroditism cause by mutation of testicular 17-β-hdroxysteroid dehydrogenase 3. Nat Genet 1994; 7: 34-9.
    • (1994) Nat Genet , vol.7 , pp. 34-39
    • Geissler, W.M.1    Davis, D.L.2    Wu, L.3    Bradshaw, K.D.4    Patel, S.5    Mendonca, B.B.6
  • 10
    • 0028847134 scopus 로고
    • Molecular cloning of a novel widely expressed human 80 kDa 17-β-hdroxysteroid dehydrogenase 4
    • Adamski J, Normand T, Leenders F, Monte D, Begue A, Stehelin D, et al. Molecular cloning of a novel widely expressed human 80 kDa 17-β-hdroxysteroid dehydrogenase 4. Biochem J 1995; 322: 437-43.
    • (1995) Biochem J , vol.322 , pp. 437-443
    • Adamski, J.1    Normand, T.2    Leenders, F.3    Monte, D.4    Begue, A.5    Stehelin, D.6
  • 11
    • 0032914659 scopus 로고    scopus 로고
    • Localization of type 5 17beta-hydroxysteroid dehydrogenase, 3beta-hydroxysteroid dehydrogenase, and androgen receptor in the human prostate by in situ hybridization and immunocytochemistry
    • El-Alfy M, Luu-The V, Huang XF, Berger L, Labrie F, Pelletier G. Localization of type 5 17beta-hydroxysteroid dehydrogenase, 3beta-hydroxysteroid dehydrogenase, and androgen receptor in the human prostate by in situ hybridization and immunocytochemistry. Endocrinology 1999; 140: 1481-91.
    • (1999) Endocrinology , vol.140 , pp. 1481-1491
    • El-Alfy, M.1    Luu-The, V.2    Huang, X.F.3    Berger, L.4    Labrie, F.5    Pelletier, G.6
  • 12
    • 0027407567 scopus 로고
    • Detection of polymorphisms in the estradiol 17 beta-hydroxysteroid dehydrogenase H gene at the EDH17B2 locus on 17q11-q21
    • Normand T, Narod S, Labrie F, Simard J. Detection of polymorphisms in the estradiol 17 beta-hydroxysteroid dehydrogenase H gene at the EDH17B2 locus on 17q11-q21. Hum Mol Genet 1993; 2: 479-83.
    • (1993) Hum Mol Genet , vol.2 , pp. 479-483
    • Normand, T.1    Narod, S.2    Labrie, F.3    Simard, J.4
  • 14
    • 0032975707 scopus 로고    scopus 로고
    • Unique multifunctional HSD17B4 gene product: 17beta-hydroxysteroid dehydrogenase 4 and D-3-hydroxyacyl-coenzyme A dehydrogenase/hydratase involved in Zellweger syndrome
    • de Launoit Y, Adamski J. Unique multifunctional HSD17B4 gene product: 17beta-hydroxysteroid dehydrogenase 4 and D-3-hydroxyacyl-coenzyme A dehydrogenase/hydratase involved in Zellweger syndrome. J Mol Endocrinol 1999; 22: 227-40.
    • (1999) J Mol Endocrinol , vol.22 , pp. 227-240
    • De Launoit, Y.1    Adamski, J.2
  • 16
    • 0031193330 scopus 로고    scopus 로고
    • Cytochrome P450 metabolism of estradiol in hamster liver and kidney
    • Hammond DK, Zhu BT, Wang MY. Cytochrome P450 metabolism of estradiol in hamster liver and kidney. Toxicol Appl Pharmacol 1997; 145: 51-60.
    • (1997) Toxicol Appl Pharmacol , vol.145 , pp. 51-60
    • Hammond, D.K.1    Zhu, B.T.2    Wang, M.Y.3
  • 17
  • 18
    • 0026879487 scopus 로고
    • Determination of CYP1A2 and NAT2 Phenotypes in Human Population by Analysis of Caffeine Urinary Metabolites
    • Butler MA, Lang NP, Young JF, Caporaso NE, Vineis P, Hayes RB, et al. Determination of CYP1A2 and NAT2 Phenotypes in Human Population by Analysis of Caffeine Urinary Metabolites. Pharmacogenetics 1992; 2: 116-27.
    • (1992) Pharmacogenetics , vol.2 , pp. 116-127
    • Butler, M.A.1    Lang, N.P.2    Young, J.F.3    Caporaso, N.E.4    Vineis, P.5    Hayes, R.B.6
  • 19
    • 0033980363 scopus 로고    scopus 로고
    • Phenotypic polymorphism and gender-related difference of CYP1A2 activity in a Chinese population
    • Ouyan DS, Huang SL, Wang W, Xie HG, Xu ZH, Zhou HH. Phenotypic polymorphism and gender-related difference of CYP1A2 activity in a Chinese population. Br J Clin Pharmacol 2000; 49: 145-51.
    • (2000) Br J Clin Pharmacol , vol.49 , pp. 145-151
    • Ouyan, D.S.1    Huang, S.L.2    Wang, W.3    Xie, H.G.4    Xu, Z.H.5    Zhou, H.H.6
  • 20
    • 0032969730 scopus 로고    scopus 로고
    • Detection of a novel cytochrome P-450 1A2 polymorphism (F21L) in Chinese
    • Huang JD, Guo WC, Lai MD, Guo YL, Lambert GH. Detection of a novel cytochrome P-450 1A2 polymorphism (F21L) in Chinese. Drug Metab Dispos 1999; 27: 98-101.
    • (1999) Drug Metab Dispos , vol.27 , pp. 98-101
    • Huang, J.D.1    Guo, W.C.2    Lai, M.D.3    Guo, Y.L.4    Lambert, G.H.5
  • 21
    • 0032929010 scopus 로고    scopus 로고
    • Genetic polymorphism in the 5′-flanking region of human CYP1A2 gene: Effect on the CYP1A2 inducibility in humans
    • Nakajima M, Yokoi T, Mizutani M, Kinoshita M, Funayama M, Kamataki T. Genetic polymorphism in the 5′-flanking region of human CYP1A2 gene: effect on the CYP1A2 inducibility in humans. J Biochem (Tokyo) 1999; 125: 803-8.
    • (1999) J Biochem (Tokyo) , vol.125 , pp. 803-808
    • Nakajima, M.1    Yokoi, T.2    Mizutani, M.3    Kinoshita, M.4    Funayama, M.5    Kamataki, T.6
  • 22
    • 0032908778 scopus 로고    scopus 로고
    • Functional significance of a C→ A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine
    • Sachse C, Brockmoller J, Bauer S, Roots I. Functional significance of a C→ A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine. Br J Clin Pharmacol 1999; 47: 445-9.
    • (1999) Br J Clin Pharmacol , vol.47 , pp. 445-449
    • Sachse, C.1    Brockmoller, J.2    Bauer, S.3    Roots, I.4
  • 23
    • 0032547341 scopus 로고    scopus 로고
    • Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4
    • Rebbeck TR, Jaffe JM, Walker AH, Wein AJ, Malkowicz SB. Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4. J Natl Cancer Inst 1998; 90: 1225-9.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1225-1229
    • Rebbeck, T.R.1    Jaffe, J.M.2    Walker, A.H.3    Wein, A.J.4    Malkowicz, S.B.5
  • 24
    • 0345643389 scopus 로고    scopus 로고
    • Interindividual differences in hepatic expression of CYP3A4: Relationship to genetic polymorphism in the 5′-upstream regulatory region
    • Westlind A, Lofberg L, Tindberg N, Andersson TB, Ingelman-Sundberg M. Interindividual differences in hepatic expression of CYP3A4: relationship to genetic polymorphism in the 5′-upstream regulatory region. Biochem Biophys Res Commun 1999; 259: 201-5.
    • (1999) Biochem Biophys Res Commun , vol.259 , pp. 201-205
    • Westlind, A.1    Lofberg, L.2    Tindberg, N.3    Andersson, T.B.4    Ingelman-Sundberg, M.5
  • 25
    • 0026010929 scopus 로고
    • Cimetidine Inhibits Catechol Estrogen Metabolism in Women
    • Michnovicz JJ, Glbraith RA. Cimetidine Inhibits Catechol Estrogen Metabolism in Women. Metab Clin Exp 1991; 40: 170-4.
    • (1991) Metab Clin Exp , vol.40 , pp. 170-174
    • Michnovicz, J.J.1    Glbraith, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.