Detection of a novel cytochrome P-450 1A2 polymorphism (F21L) in Chinese

Drug Metabolism and Disposition

Volumn 27, Issue 1, 1999, Pages 98-101

  Huang, Jin Ding ^a,c   Guo, Wei Chung ^a   Lai, Ming Derg ^a   Guo, Yueleong Leon ^a   Lambert, George H ^b  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; CYTOCHROME P450; DNA; ENDONUCLEASE; POLYCHLORINATED BIPHENYL;

ARTICLE; BREATH ANALYSIS; CHINESE; CONTROLLED STUDY; DNA SEQUENCE; EXON; GENETIC POLYMORPHISM; HUMAN; HUMAN EXPERIMENT; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM;

EID: 0032969730     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Benoit GG, Naud CF, Simard MA and Astier AL (1997) Noninterference of cytochrome P-4501A2 in the cytotoxicity of tacrine by genetically engineered V79 Chinese hamster cells for stable expression of the human or rat isoform and two human hepatocyte cell lines. Biochem Pharmacol 53:423-427.
2. Blin N and Stafford DW (1976) A general method for isolation of high molecular weight DNA from leukocytes. Nucleic Acids Res 3:2303-2308.
3. Boobis AR, Lynch AM, Murray S, de la Torre R, Solans A, Farre M, Segura J. Gooderham NJ and Davis DS (1994) CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogen is their major route of metabolism in humans. Cancer Res 54:89-94.
4. Butler MA, Lang NP, Young JF, Caporaso NE, Vineis P, Hayes RB, Teitel CH, Massaengill JP, Lawsen MF and Kadlubar FF (1992) Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites. Pharmacogenetics 2:116-127.
5. Denaro CP, Wilson M, Jacob P and Benowitz NL (1996) Validation of urine caffeine metabolic ratios with use of stable isotope-labeled caffeine clearance. Clin Pharmacol Ther 59:284-296.
6. Eaton DL, Gallagher EP, Bammler TK and Kunze KL (1995) Role of cytochrome P4501A2 in chemical carcinogenesis: implications for human variability in expression and enzyme activity. Pharmacogenetics 5:259-274.
7. Edwards RJ, Murray BP, Boobis AR and Davies DS (1989) Identification and location of α-helices in mammalian cytochromes P450. Biochemistry-28:3762-3770.
8. Fuhr U and Rost KL (1994) Simple and reliable CYP1A2 phenotyping by the paraxanthine/ caffeine ratio in plasma and in saliva. Pharmacogenetics 4:109-116.
9. Fuhr U, Rost KL, Engelhardt R, Sachs M, Liermann D, Belloc C, Beaune P, Janezic S, Grant D, Meyer UA and Staib AH (1996) Evaluation of caffeine as a test drug for CYP1A2 NAT2 and CYP2E1 phenotyping in man by in vivo versus in vitro correlations Pharmacogenetics 6:159-176.
10. Hammons GJ, Milton JD, Stepps K, Tukey RH and Kadlubar FF (1997) Metabolism of carcinogenic heterocyclic and aromatic amines by recombinant human cytochrome P450 enzymes. Carcinogenesis 18:851-854.
11. Ikeya K, Jaiswal AK, Owens RA, Jones JE, Neben DW and Kimura S (1989) Human CYP1A2: sequence, gene structure, comparison with mouse and rat orthologous gene, and differences in liver 1A2 mRNA expression. Mol Endocrinol 3:1399-1408.
12. Jaiswal AK, Nebert DW and Gonzalez FJ (1986) Human P3 450: cDNA and complete amino acid sequence. Nucleic Acid Res 14:6773-6774.
13. Johansson I, Yue QY, Dahl ML, Heim M, Sawe J, Bertilsson L, Meyer UA, Sjoqvist F and Ingelman-Sundberg M (1991) Genetic analysis of the interethnic differences between Chinese and Caucasians in the polymorphic metabolism of debrisoquine and codeine. Ear J Clin Pharmacol 40:553-556.
14. Kalow W and Tang BK (1991) Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities. Clin Pharmacol Ther 50:508-519.
15. Koyama E, Chiba K, Tani M and Ishizaki T (1996) Identification of human cytochrome P450 isoforms involved in the stereoselective metabolism of mianserin enantiomers. J Pharmacol Exp Ther 278:21-30.
16. Koyama E, Chiba K, Tani M and Ishizaki T (1997) Reappraisal of human CYP isoforms involved in imipramine N-demethylation and 2-hydroxylation: A study with microsomes obtained from putative extensive and poor metabolizers of S-mephenytoin and eleven recombinant human CYPs. J Pharmacol Exp Ther 281:1199-1210.
17. Marez D, Legrand M, Sabbagh N, Lo Guidice JM, Spire C, Lafitte JJ, Meyer UA and Broly R (1997) Polymorphism of the cytochrome P450 2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution. Pharmacogenetics 7:193-202.
18. Miners JO and Birkett DJ (1996) The use of caffeine as a metabolic probe for human drug metabolizing enzyme. Gen Pharmacol 27:245-249.
19. Nakajima M, Yokoi T, Mizutami M, Shin S, Kadlubar FF and Kamataki T (1994) Phenotyping of CYP1A2 in Japanese population by analysis of caffeine urinary metabolites: absence of mutation prescribing the phenotype in the CYP1A2 gene. Cancer Epidemiol Biomarkers Prevention 3:413-421.
20. Nakajima T, Wang RS, Elovaara E, Gonzalez FJ, Gelboin HV, Raunio H, Pelkonen O, Vainio H and Aoyama T (1997) Toluene metabolism by cDNA-expressed human hepatic cytochrome P450. Biochem Pharmacol 53:271-277.
21. Nelson DR and Strobel HW (1988) On the membrane topology of vertebrate cytochrome P-450 proteins. J Biol Chem 263:6038-6050.
22. Olesen OV and Linnet K (1997) Hydroxylation and demethylation of the tricyclic antidepressant nortriptyline by cDNA-expressed human cytochrome P-450 isozymes. Drug Metab Dispos 25:740-744.
23. Quattrochi LC, Rendurthi UR, Okino ST, Potenza C and Tukey RH (1986) Human cytochrome P-450 4 mRNA and gene: Part of a multigene family that contains Alu sequences in its mRNA. Proc Natl Acad Sci USA 83:6731-6735.
24. Raza H, King RS, Squires RB, Guengerich FP, Miller DW, Freeman JP, Lang NP and Kadlubar FF (1996) Metabolism of 2-amino-alpha-carboline-A food-borne heterocyclic amine mutagen and carcinogen by human and rodent liver microsomes and by human cytochrome P4501A2. Drug Metab Dispos 24:395-400.
25. Ring BJ, Callow J, Lindsay TJ, Gillespie T, Roskos LK, Cerimele BJ, Swanson SP, Hamman MA and Wrighron SA(1996) Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine. J Pharmacol Exp Ther 276:658-666.
26. Roh HK, Dahl ML, Johansson I, Ingelman-Sunderberg M, Cha YN and Bertilsson L (1996) Debrisoquine and S-mephenytoin hydroxylation phenotypes and genotypes in a Korean population. Pharmacogenetics 6:441-447.
27. Sanger F, Nicklens S and Coulsen AR (1977) DNA sequencing with chain termination inhibitors. Proc Natl Acad Sci USA 74:5463-5467.
28. Sharer JE and Wrighton SA (1996) Identification of the human hepatic cytochrome P450 involved in the in vitro oxidation of antipyrine. Drug Metab Dispos 24:487-494.
29. Shel MS, Mcphaul M. Fisher CW, Stallings NR and Estabrook RW (1997) Metabolism of the antiandrogenic drug (flutamide) by human CYP1A2. Drug Metab Dispos 25:1298-1303.
30. Shou MG, Korzekwa KR, Brooks EN, Krausz KW, Gonzalez FJ and Gelboin HV (1997) Role of human hepatic cytochrome P450 1A2 and 3A4 in the metabolic activation of estrone. Carcinogenesis 18:207-214.
31. Smith TJ, Guo ZY, Guengerich FP and Yang CS (1996) Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate. Carcinogenesis 17:809-813.
32. Tracy TS, Mana C, Wrighton SA, Gonzalez FJ, Korzekwa KR (1997) Involvement of multiple cytochrome P450 isoforms in naproxen O-demethylation. Eur J Clin Pharmacol 52:293-298.
33. Wang SL, Huang JD, Lai MD, Liu BH and Lai ML (1993) Molecular basis of genetic variation in debrisoquine hydroxylation in Chinese subjects: Polymorphism in RFLP and DNA sequence of CYP2D6. Clin Pharmacol Ther 53:410-418.
34. Yamazaki H, Inoue K, Mimura M, Oda Y, Guengerich FP and Shimada T (1996) 7-ethoxycou-marin O-deethylation catalyzed by cytochrome P450 1A2 and 2E1 in human liver microsomes. Biochem Pharmacol 51:313-319.
35. Zhang Z, Fasco MJ, Huang Z, Guengerich FP and Kaminsky LS (1995) Human cytochrome P4501AJ and P4501A2: R-warfarin metabolism as a probe. Drug Metab Dispos 23:1339-1345.