Leukocyte CD11b expression is not essential for the development of atherosclerosis in mice

Journal of Lipid Research

Volumn 41, Issue 7, 2000, Pages 1060-1066

  Kubo, Nobuhiko ^a   Boisvert, William A ^a   Ballantyne, Christie M ^b   Curtiss, Linda K ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Adhesion molecules; Fluorescenceactivated cell sorting; In vivo animal models; Inflammation; Transgenic knockout

Indexed keywords

BETA2 INTEGRIN; CD11B ANTIGEN; INTEGRIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; ATHEROSCLEROSIS; BONE MARROW TRANSPLANTATION; CELL ADHESION; DISEASE ASSOCIATION; IMMUNOHISTOCHEMISTRY; LIPID DIET; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, CD18; AORTA; AORTIC VALVE; ARTERIOSCLEROSIS; BONE MARROW TRANSPLANTATION; HYPERCHOLESTEROLEMIA; LEUKOCYTES; MACROPHAGE-1 ANTIGEN; MACROPHAGES; MALE; MICE; MICE, MUTANT STRAINS; RADIATION CHIMERA; RECEPTORS, LDL;

EID: 0033942168     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Carlos, T. M., and J. Harlan. 1990. Membrane proteins involved in phagocyte adherence to endothelium. Immunol. Rev. 114: 5-28.
2. Mazzone, A., and G. Ricevuti. 1995. Leukocyte CD11/CD18 integrins: biological and clinical relevance. Haematologica. 80: 161-175.
3. Larson, R. S., and T. A. Springer. 1990. Structure and function of leukocyte integrins. Immunol. Rev. 114: 181-217.
4. van der Vieren, M., H. Le Trong, C. L. Wood., P. F. Moore, T. St. John, D. E. Staunton, and W. M. Gallatin. 1995. A novel leukointegrin, alpha d beta 2, hinds preferentially to ICAM-3. Immunity. 3: 683-690.
5. Springer, T. A., G. Galfré, D. S. Secher, and G. Milstein. 1979. Mac-1: a macrophage differentiation antigen identified by monoclonal antibody. Eur. J. Immunol 9: 301-306.
6. Beller, D. I., T. A. Springer, and R. D. Schreiber. 1982. Anti-Mac-1 selectively inhibits the mouse and human type three complement receptor. J. Exp. Med. 156: 1000-1009.
7. Mcfarland, H. I., S. R. Nahill, J. W. Maciaszek, and R. M. Welsh. 1992. CD11b(Mac-1): a marker for CD8+ cytotoxic T cell activation and memory in virus infection. J. Immunol. 149: 1326-1333.
8. Ault, K. A., and T. A. Springer. 1981. Cross reaction of a rat-anti-mouse phagocyte-specific monoclonal antibody (anti-Mac-1) with human monocytes and natural killer cells. J. Immunol. 126: 359-364.
9. Carlos, T. M., A. Dobrina, R. Ross, and J. M. Harlan. 1990. Multiple receptors on human monocytes are involved in adhesion to cultured human endothelial cells. J. Leukocyte Biol. 48: 451-456.
10. Beekhuizen, H., A. J. Corsèl-Van Tilburg, and R. Van Furth. 1990. Characterization of monocyte adherence to human macrovascular and microvascular endothelial cells. J. Immunol. 145: 510-518.
11. Hakkert, B. C., T. W. Kuijpers, J. F. M. Leeuwenberg, J. A. Van Mourik, and D. Roos. 1991. Neutrophil and monocyte adherence to and migration across monolayers of cytokine-activated endothelial cells: the contribution of CD18, ELAM-1, and VLA-4. Blood. 78: 2721-2726.
12. Watanabe, T., S. Hamaoka, and T. Shimokawa. 1996. Inflammatory and immunological nature of atherosclerosis. Int. J. Cardiol. 54 (Suppl.):S51-S60.
13. Stemme, S., B. Faber, J. Holm, O. Wiklund, J. L. Witztum, and G. K. Hansson. 1995. T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein. Proc. Natl. Acad. Sci. USA. 92: 3893-3897.
14. Seko, Y., O. Sato, A, Takagi, Y. Tada, H. Matsuo, H. Yagita, K. Okumura, and Y. Yazaki. 1997. Perforin-secreting killer cell infiltration in the aortic tissue of patients with atherosclerotic aortic aneurysm. Jpn. Cirr. J. 61: 965-970.
15. Gerrity, R. G. 1981. The role of monocyte in atherogenesis. I. Transition of blood-borne monocytes into foam cells in fatty lesions. Am. J. Pathol 103: 181-190.
16. Bauriedel, G., S. Schluckebier, R. Hutter, U. Welsch, R. Kandolf, B. Lüderitz, and M. F. Prescott. 1998. Apoptosis in restenosis versus stable-angina atherosclerosis. Implication for the pathogenesis of restenosis. Arterioscler. Thromb. Vasc. Biol. 18: 1132-1139.
17. Rosen, H., G. Milton, and S. Gordon. 1989. Antibody to the murine type 3 complement receptor inhibits T lymphocyte-dependent recruitment of myelomonocytic cells in vivo. J. Exp. Med. 169: 535-548.
18. Mecrshaert, J., and M. B. Furie. 1994. Monocytes use either CD11b/CD18 or VLA-4 to migrate across human endothelium in vitro. J. Immunol. 152: 1915-1926.
19. Crockett-Torabi, E. Selectins and mechanisms of signal transduction. 1998. J. Leukocyte Biol. 63: 1-14.
20. Johnson, R. C., S. M. Chapman, Z. M. Dong, J. M. Ordovas, T. N. Mayadas, J. Herz, R. O. Hynes, E. J. Schaefer, and D. D. Wagner. 1997. Absence of P-selectin delays fatty streak formation in mice. J. Clin. Invest. 99: 1037-1043.
21. Dong, Z. M., S. M. Chapman, A. A. Brown, P. S. Frenette, R. O. Hynes, and D. D. Wagner. 1998. The combined role of P- and E-selectins in atherosclerosis. J. Clin. Invest. 102: 145-152.
22. Gijbels, M. J. J., M. van der Cammen, L. J. W. van der Laan, J. J. Emeis, L. M. Havckes, M. H. Hofker, and G. Kraal. 1999. Progression and regression of atherosclerosis in APOE3-Leiden transgenic mice: an immunohistochemical study. Atherosclerosis. 143: 15-25.
23. Lu, H., C. W. Smith, J. Perrard, D. Bullard, L. Tang, S. B. Shappell, M. L. Entman, A. L. Beaudet, and C. M. Ballantyne. LFA-1 is sufficient in mediating neutrophil emigration in Mac-1 deficient mice. J. Clin. Invest. 99: 1340-1350.
24. Ishibashi, S., J. L. Goldstein, M. S. Brown, J. Herz, and D. K. Burns. 1994. Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice. J. Clin. Invest. 93: 1885-1893.
25. Boisvert, W. A., J. Spangenberg, and Linda K. Curtiss. 1997. Role of leukocyte-specific LDL receptors on plasma lipoprotein cholesterol and atherosclerosis in mice. Arterioscler. Thromb. Vasc. Biol. 17: 340-347.
26. Boisvert, W. A., J. Spangenberg, and Linda K. Curtiss. 1995. Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantation. J. Clin. Invest. 96: 1118-1124.
27. Boisvert, W. A., R. Santiago, L. K. Curtiss, and R. A. Terkeltaub. 1998. A leukocyte homologue of IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesion of LDI. receptor-deficient mice. J. Clin. Invest. 101: 353-363.
28. Paigen, B., P. A. Morrow, D. Holmes, D. Mitchell, and R. A. Williams. 1987. Quantitative assessment of atherosclerotic lesions in mice. Atherosclerosis. 68: 231-240.
29. Tangirala, R. K., E. M. Rubin, and W. Palinski, 1995. Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesion between sexes in LDI. receptor-deficient and apolipoprotein E-deficient mice. J. Lipid Res. 36: 2320-2328.
30. Springer, T. A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradim. Cell 76: 301-314.
31. Nageh, M. F., E. T. Sandberg, K. R. Marotti, A. H. Lin, E. R Melchior, D. C. Bullard, and A. L. Beaudet. 1997. Deficiency of inflammatory cell adhesion molecules protects against atherosclerosis in mice, Arteroscler. Thromb. Vasc. Biol. 17: 1517-1520.
32. -/- mice reveals a role for ahemokines in the initiation of atherosclerosis. Nature. 394: 894-897.