Role of leukocyte-specific LDL receptors on plasma lipoprotein cholesterol and atherosclerosis in mice

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 17, Issue 2, 1997, Pages 340-347

  Boisvert, William A ^a   Spangenberg, Jörg ^a   Curtiss, Linda K ^a,b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b Department of Vascular Biology ^*  (United States)

Author keywords

atherogenic diet; bone marrow transplantation; gene transfer; immunohistochemistry; mouse model

Indexed keywords

HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; BONE MARROW TRANSPLANTATION; CHOLESTEROL METABOLISM; CONTROLLED STUDY; HISTOPATHOLOGY; LIPOPROTEIN BLOOD LEVEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; TISSUE DISTRIBUTION;

EID: 0031025261     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.17.2.340     Document Type: Article

References (26)

1. Goldslein JL, Hobbs HH, Brown MS. Familial hypercholesterolemia. In: Scriver CR, Beaudet AL, Sly WS, Valle D, eds. The Metabolic and Molecular Basis of Inherited Diseases. New York, NY: McGraw-Hill Inc; 1995:1981-2030.
2. Ishibashi S, Brown MS, Goldstein JL, Gerard RD, Hammer RE, Herz J. Hyper-cholesterolemia in LDL receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J Clin Invest. 1993;92:883-893.
3. Ishibashi S, Goldstein JL, Brown MS, Herz J, Burns DK. Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice. J Clin Invest. 1994;93:1885-1893.
4. Higuchi K, Kitagawa K, Kogishi K, Takeda T. Developmental and age-related changes in apoprotein B mRNA editing in mice. J Lipid Res. 1992;33:1753-1764.
5. Boisvert WA, Spangenberg J, Curtiss LK. Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantation. J Clin Invest. 1995;96:1118-1124.
6. Linton ME, Atkinson JB, Sergio F. Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation. Science. 1995;267:1034-1037.
7. Fogelman AM, Schecter I, Seager J, Hokom M, Child JS, Edwards PA. Malondialdehyde alterations of low density lipoproteins leads to cholesterol ester accumulation in human monocyte-macrophages. Proc Natl Acad Sci USA. 1980;77:5466-5470.
8. Traber MG, Kayden HJ. Low density lipoprotein receptor activity in human monocyte-derived macrophages and its relation to atheromatous lesions. Proc Natl Acad Sci USA. 1980;77:5466-5470.
9. Fogelman AM, Haberland ME, Seager J, Hokom M, Edwards PA. Factors regulating the activities of the low density lipoprotein receptor and the scavenger receptor on human monocyte-macrophages. J Lipid Res. 1981;22:1131-1141.
10. Via DP, Plant AL, Craig IF, Gotto AM Jr, Smith LC. Metabolism of normal and modified low-density lipoproteins by macrophage cell lines of murine and human origin. Biochim Biophys Acta. 1985;833:417-428.
11. Tabas I, Weiland DA, Tall AR. Unmodified low density lipoprotein causes cholesteryl ester accumulation in J774 macrophages. Proc Natl Acad Sci USA. 1985;82:416-420.
12. Cuthbert JA, East CA, Bilheimer DW, Lipsky PE. Detection of familial hypercholesterolemia by assaying functional low-density-lipoprotein receptors on lymphocytes. N Engl J Med. 1986;314:879-883.
13. Goldstein JL, Brown MS. The low density lipoprotein pathway and its relation to atherosclerosis. Annu Rev Biochem. 1977;46:897-930.
14. Curtiss LK, Edgington TS. Identification of a lymphocyte surface receptor for low density lipoprotein inhibitor, an immunoregulatory species of normal human serum low density lipoprotein. J Clin Invest. 1978;61:1298-1308.
15. Cuthbert JA, Russell DW, Lipsky PE. Regulation of low density lipoprotein receptor gene expression in human lymphocytes. J Biol Chem. 1989;264:1298-1304.
16. Cuthbert JA, Lipsky PE. Provision of cholesterol to lymphocytes by high density and low density lipoproteins: requirement for low density lipoprotein receptors. J Biol Chem. 1987;262:7808-7818.
17. Ellsworth JL, Kraemer FB, Cooper AD. Transport of β-very low density lipoproteins and chylomicron remnants by macrophages is mediated by the low density lipoprotein receptor pathway. J Biol Chem. 1987;262:2316-2325.
18. Banka CL, Black AS, Dyer CA, Curtiss LK. THP-1 cells form foam cells in response to coculture with lipoproteins but not platelets. J Lipid Res. 1991;32:35-43.
19. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 1993;362:801-809.
20. Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. Beyond cholesterol: modifications of low density lipoprotein that increases its atherogenicity. N Engl J Med. 1989;320:915-924.
21. Hansson GK, Holm J, Jonasson L. Detection of activated T lymphocytes in the human atherosclerotic plaque. Am J Pathol. 1989;135:169-175.
22. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 1987;162:156-159.
23. Brown MS, Goldstein JL. Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. Annu Rev Biochem. 1983;52:223-261.
24. Tabas I, Weiland DA, Tall AR. Inhibition of acyl coenzyme A:cholesterol acyl transferase in J774 macrophages enhances down-regulation of the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl-coenzyme A reductase and prevents low density lipoprotein-induced accumulation. J Biol Chem. 1986;261:3147-3155.
25. Schlechter I, Fogelman AM, Haberland ME, Seager J, Hokom M, Edwards PA. The metabolism of native and malondialdehyde-altered low density lipoproteins by human monocyte-macrophages. J Lipid Res. 1981;22:63-71.
26. Smith EB. Plasma macromolecules in interstitial fluid from normal and atherosclerotic human sera. Monogr Atheroscler. 1986;14:179-183.