Pseudoexons and regulatory elements in the genomic sequence of the β-chemokine, alternative macrophage activation-associated CC-chemokine (AMAC)-1

Cytokine

Volumn 12, Issue 2, 2000, Pages 120-126

  Politz, Oliver ^a   Kodelja, Vitam ^a   Guillot, Pierre ^a   Orfanos, Constantin E ^a   Goerdt, Sergij ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CHEMOKINE; INTERLEUKIN 4; STAT1 PROTEIN; STAT6 PROTEIN;

ARTICLE; BINDING SITE; EXON; GENE ISOLATION; GENE SEQUENCE; GENOME; HUMAN; INTRON; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; TRANSCRIPTION REGULATION;

EID: 0033933071     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.1999.0538     Document Type: Article

References (40)

1. Stein M, Keshav S, Gordon S. Interleukin-4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J Exp Med. 176:1992;287-292.
2. Hogger P, Dreier J, Droste A, Buck F, Sorg C. Identification of the integral membrane protein RM3/1 on human monocytes as a glucocorticoid-inducible member of the scavenger receptor cysteine-rich family (CD163). J Immunol. 161:1998;1883-1890.
3. Goerdt S, Walsh LJ, Murphy GF, Pober JS. Identification of a novel high molecular weight protein preferentially expressed by sinusoidal endothelial cells in normal human tissues. J Cell Biol. 113:1991;1425-1437.
4. Goerdt S, Bhardwaj R, Sorg C. Inducible expression of MS-1 high-molecular-weight protein by endothelial cells of continuous origin and by dendritic cells/macrophages in vivo and in vitro. Am J Pathol. 142:1993;1409-1422.
5. Djemadji-Oudjiel N, Goerdt S, Kodelja V, Schmuth M, Orfanos CE. Immunohistochemical identification of type II alternatively activated dendritic macrophages (RM 3/1+3, MS-1+/-, 25F9-) in psoriatic dermis. Arch Dermatol Res. 288:1996;757-764.
6. Kodelja V, Müller C, Tenorio S, Schebesch C, Orfanos CE, Goerdt S. Differences in angiogenic potential of classically vs. alternatively activated macrophages. Immunobiology. 197:1997;478-493.
7. Schebesch C, Kodelja V, Müller C, Hakiy N, Bisson S, Orfanos CE, Goerdt S. Alternatively activated macrophages actively inhibit proliferation of peripheral blood lymphocytes and CD4+ T cells in vitro. Immunology. 92:1997;478-486.
8. Goerdt S, Orfanos CE. Other functions, other genes: alternative activation of antigen presenting cells. Immunity. 10:1999;137-142.
9. Kodelja V, Müller C, Politz O, Hakiy N, Orfanos CE, Goerdtt S. Alternative macrophage activation-associated CC-chemokine-1, a novel structural homologue of macrophage inflammatory protein-1 alpha with a Th2-associated expression pattern. J Immunol. 160:1998;1411-1418.
10. Adema GJ, Hartgers F, Verstraten R, de Vries E, Marland G, Menon S, Foster J, Xu Y, Nooyen P, McClanahan T, Bacon KB, Figdor CG. A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells. Nature. 387:1997;713-717.
11. Hieshima K, Imai T, Baba M, Shoudai K, Ishizuka K, Nakagawa T, Tsuruta J, Takeya M, Sakaki Y, Takatsuki K, Miura R, Opdenakker G, Van Damme J, Yoshie O, Nomiyama H. A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1 alpha/LD78 alpha and chemotactic for T lymphocytes, but not for monocytes. J Immunol. 159:1997;1140-1149.
12. Kodelja V, Kraft S, Politz O, Hakiy N, Treudler R, Orfanos CE, Bieber T, Goerdt S. Langerhans cells do not express alternative macrophage activation-associated CC chemokine (AMAC)-1. Res Immunology. 149:1998;633-637.
13. Altschul S, Gish W, Miller W, Myers E, Lipman D. Basic local alignment search tool. J Mol Biol. 215:1990;403-410.
14. Solovyev VV, Salamov AA, Lawrence CB. Predicting internal exons by oligonucleotide composition and discriminant analysis of spliceable open reading frames. Nucleic Acids Res. 22:1994;5156-5163.
15. Naruse K, Ueno M, Satoh T, Nomiyama H, Tei H, Takeda M, Ledbetter DH, Coillie EV, Opdenakker G, Gunge N, Sakaki Y, Iio M, Miura R. A YAC contig of the human CC chemokine genes clustered on chromosome 17q11.2. Genomics. 34:1996;236-240.
16. Valentine CR. The association of nonsense codons with exon skipping. Mutat Res. 411:1998;87-117.
17. Lou H, Helfman DM, Gagel RF, Berget SM. Polypyrimidine Tract-Binding Protein Positively Regulates Inclusion of an Alternative 3′-Terminal Exon. Mol Cell Biol. 19:1999;78-85.
18. Coy JF, Dubel S, Kioschis P, Thomas K, Micklem G, Delius H, Poustka A. Molecular cloning of tissue-specific transcripts of a transketolase-related gene: implications for the evolution of new vertebrate genes. Genomics. 32:1996;309-316.
19. Fenghao X, Saxon A, Nguyen A, Ke Z, Diaz-Sanchez D, Nel A. Interleukin 4 activates a signal transducer and activator of transcription (Stat) protein which interacts with an interferon-gamma activation site-like sequence upstream of the I epsilon exon in a human B cell line. Evidence for the involvement of Janus kinase 3 and interleukin-4 Stat. J Clin Invest. 96:1995;907-914.
20. Horvai AE, Xu L, Korzus E, Brard G, Kalafus D, Mullen TM, Rose DW, Rosenfeld MG, Glass CK. Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300. Proc Natl Acad Sci U S A. 94:1997;1074-1079.
21. Kaplan MH, Schindler U, Smiley ST, Grusby MJ. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity. 4:1996;313-319.
22. Mikita T, Campbell D, Wu P, Williamson K, Schindler U. Requirements for interleukin-4-induced gene expression and functional characterization of Stat6. Mol Cell Biol. 16:1996;5811-5820.
23. Dickensheets HL, Donnelly RP. IFN-gamma and IL-10 inhibit induction of IL-1 receptor type I and type II gene expression by IL-4 and IL-13 in human monocytes. J Immunol. 159:1997;6226-6233.
24. Sharma B, Iozzo RV. Transcriptional silencing of perlecan gene expression by interferon-gamma. J Biol Chem. 273:1998;4642-4646.
25. Albrecht B, Peiritsch S, Woisetschlager M. A bifunctional control element in the human IgE germline promoter involved in repression and IL-4 activation. Int Immunol. 6:1994;1143-1151.
26. Curiel RE, Lahesmaa R, Subleski J, Cippitelli M, Kirken RA, Young HA, Ghosh P. Identification of a Stat-6-responsive element in the promoter of the human interleukin-4 gene. Eur J Immunol. 27:1997;1982-1987.
27. Heydeck D, Thomas L, Schnurr K, Trebus F, Thierfelder WE, Ihle JN, Kuhn H. Interleukin-4 and -13 induce upregulation of the murine macrophage 12/15-lipoxygenase activity: evidence for the involvement of transcription factor STAT6. Blood. 92:1998;2503-2510.
28. Kotanides H, Reich NC. Interleukin-4-induced STAT6 recognizes and activates a target site in the promoter of the interleukin-4 receptor gene. J Biol Chem. 271:1996;25555-25561.
29. Minty A, Asselin S, Bensussan A, Shire D, Vita N, Vyakarnam A, Wijdenes J, Ferrara P, Caput D. The related cytokines interleukin-13 and interleukin-4 are distinguished by differential production and differential effects on T lymphocytes. Eur Cytokine Netw. 8:1997;203-213.
30. Ohmori Y, Smith MF Jr., Hamilton TA. IL-4-induced expression of the IL-1 receptor antagonist gene is mediated by STAT6. J Immunol. 157:1996;2058-2065.
31. Seidel HM, Milocco LH, Lamb P, Darnell JE Jr., Stein RB, Rosen J. Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity. Proc Natl Acad Sci U S A. 92:1995;3041-3045.
32. Kohler I, Rieber EP. Allergy-associated I epsilon and Ec epsilon receptor II (CD23b) genes activated via binding of an interleukin-4-induced transcription factor to a novel responsive element. Eur J Immunol. 23:1993;3066-3071.
33. Ihle JN. STATs: signal transducers and activators of transcription. Cell. 84:1996;331-334.
34. Darnell JE Jr. Studies of IFN-induced transcriptional activation uncover the Jak-Stat pathway. J Interferon Cytokine Res. 18:1998;549-554.
35. Darnell JE Jr., Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science. 264:1994;1415-1421.
36. Wang IM, Blanco JC, Tsai SY, Tsai MJ, Ozato K. Interferon regulatory factors and TFIIB cooperatively regulate interferon-responsive promoter activity in vivo and in vitro. Mol Cell Biol. 16:1996;6313-6324.
37. Iciek LA, Delphin SA, Stavnezer J. CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction. J Immunol. 158:1997;4769-4779.
38. Kaplan MH, Daniel C, Schindler U, Grusby MJ. Stat proteins control lymphocyte proliferation by regulating p27Kip1 expression. Mol Cell Biol. 18:1998;1996-2003.
39. Mikita T, Kurama M, Schindler U. Synergistic activation of the germline epsilon promoter mediated by Stat6 and C/EBP beta. J Immunol. 161:1998;1822-1828.
40. Shen CH, Stavnezer J. Interaction of stat6 and NF-kappaB: direct association and synergistic activation of interleukin-4-induced transcription. Mol Cell Biol. 18:1998;3395-3404.