Immunohistochemical identification of type II alternatively activated dendritic macrophages (RM 3/1+++, MS-1(±), 25F9-) in psoriatic dermis

Archives of Dermatological Research

Volumn 288, Issue 12, 1996, Pages 757-764

  Djemadji Oudjiel, Noel ^a,b   Goerdt, Sergij ^b   Kodelja, Vitam ^b   Schmuth, Matthias ^b   Orfanos, Constantin E ^b  

^a Hôpital Central de N'Djamena   (Chad)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Alternatively activated macrophages; Mononuclear phagocytes; MS 1 high molecular weight protein; Psoriasis; RM 3 1 antigen

Indexed keywords

GAMMA INTERFERON; GLUCOCORTICOID; INTERLEUKIN 4; MONOCLONAL ANTIBODY;

ARTICLE; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; DENDRITIC CELL; DERMIS; EPIDERMIS; HELPER CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; LYMPHOCYTE CLONE; MACROPHAGE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PSORIASIS; SKIN ALLERGY; T LYMPHOCYTE;

EID: 0029993831     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02505293     Document Type: Article

References (67)

1. Baker BS, Bokth S, Powles A, Garioch JJ, Lewis H, Valdimarsson H, Fry L (1993) Group A streptococcal antigen-specific T-lymphocytes in guttate psoriatic lesions. Br J Dermatol 128 : 493-499
2. Barna M, Snijdewint FGM, Heijden FL van der, Bos JD, Kapsenherg ML (1994) Characterization of lesional psoriatic skin T lymphocyte clones. Acta Derm Venerol Suppl (Stockh) 186 : 9-11
3. Beissert S, Hosoi J, Grabbe S, Asahina A, Granstein RD (1995) IL-10 inhibits tumor antigen presentation by epidermal antigen-presenting cells. J Immunol 154 : 1280-1286
4. Boehncke WH, Küenzlen C, Zollner TM, Mielke V, Sterry W (1994) Predominant usage of distinct T-cell receptor Vβ regions by epidermotropic T cells in psoriasis. Exp Dermatol 3 : 161-163
5. Caux C, Dezutter-Dambuyant C, Schmitt D, Banchereau J (1992) GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells. Nature 360 : 258-261
6. Caux C, Massacrier C, Vanbervliet B, Barthelemy C, Liu Y-J, Banchereau J (1994) Interleukin 10 inhibits T cell alloreaction induced by human dendritic cells. Int Immunol 6 : 1177-1185
7. Cowan HB, Vick S, Conary JT, Shepherd VL (1992) Dexamethasone upregulates mannose receptor activity by increasing mRNA levels. Arch Biochem Biophys 296 : 314-320
8. Dunham DM, Arkins S, Edwards CK, Dantzer R, Kelley KW (1990) Role of interferon-γ in counteracting the suppressive effects of transforming growth factor-β2 and glucocorticoids on the production of tumor necrosis factor-α. J Leukoc Biol 48 : 473-481
9. Elder JT, Nair RP, Guo S-W, Henseler T, Christophers E (1994) The genetics of psoriasis. Arch Dermatol 130 : 216-224
10. Enk AH, Angeloni VL, Udey MC, Katz SI (1993) Inhibition of Langerhans cell antigen-presenting function by IL-10. A role for IL-10 in induction of tolerance. J Immunol 151 : 2390-2398
11. Gillitzer R, Wolff K, Tong D, Müller C, Yoshimura T, Hartmann AA, Stingl G, Berger R (1993) MCP-1 mRNA expression in basal keratinocytes of psoriatic lesions. J Invest Dermatol 101 : 127-131
12. Goerdt S, Steckel F, Schulze-Osthoff K, Hagemeier H-H, Macher E, Sorg C (1989) Characterization and differential expression of an endothelial cell-specific surface antigen in continuous and sinusoidal endothelia, in skin vascular lesions and in vitro. Exp Cell Biol 57 : 185-192
13. Goerdt S, Walsh LJ, Murphy GF, Pober JS (1991) Identification of a novel high molecular weight protein antigen preferentially expressed by sinusoidal endothelial cells in normal human tissues. J Cell Biol 113 : 1425-1437
14. Goerdt S, Bhardwaj R, Sorg C (1993) Inducible expression of MS-1 high molecular weight protein by endothelial cells of continuous origin and by dendritic cells/macrophages in vivo and in vitro. Am J Pathol 142 : 1409-1422
15. Griffiths CEM (1994) Cutaneous leukocyte trafficking and psoriasis. Arch Dermatol 130 : 494-499
16. Hart PH, Ahern MJ, Jones CA, Jones KL, Smith MD, Finlay-Jones JJ (1993) Synovial fluid macrophages and blood monocytes differ in their response to IL-4. J Immunol 151 : 3370-3380
17. Heng MCY, Kloss SG, Kuehn CS, Chase DG (1986) Significance and pathogenesis of basal keratinocyte herniations in psoriasis. J Invest Dermatol 87 : 362-366
18. Heng MCY, Allen SG, Haberfelde G, Song MK (1991) Electron microscopic and immunocytochemical studies of the sequence of events in psoriatic plaque formation following tape stripping. Br J Dermatol 125 : 548-556
19. Kodelja V, Goerdt S (1994) Dissection of macrophage differentiation pathways in cutaneous macrophage disorders and in vitro. Exp Dermatol 3 : 257-268
20. Kristensen M, Deleuran B, Eedy DJ, Feldman M, Breathnach SM, Brennan FM (1992) Distribution of interleukin 1 receptor antagonist protein (IRAP), interleukin 1 receptor, and interleukin 1α in normal and psoriatic skin. Decreased expression of IRAP in psoriatic lesional epidermis. Br J Dermatol 127 : 305-311
21. Lewis HM, Baker BS, Bokth S, Powles AV, Garioch JJ, Valdimarsson H, Fry L (1993) Restricted T-cell receptor Vβ gene usage in the skin of patients with guttate and chronic plaque psoriasis. Br J Dermatol 129 : 514-520
22. Liew FY, Li Y, Severn A. Millott S, Schmidt J, Salter M, Moncada S (1991) A possible novel pathway of regulation by murine T helper type-2 (Th2) cells of a Th1 cell activity via the modulation of the induction of nitric oxide synthase on macrophages. Eur J Immunol 21 : 2489-2494
23. Manetti R, Parronchi P, Giudizi MG, Piccini MP, Maggi E, Trinchieri G, Romagnani S (1993) Natural killer cell stimulatory factor (interleukin-12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells. J Exp Med 177 : 1199-1204
24. Marianayagam L, Poulter LW (1991) Corticosteroid can alter antigen expression on alveolar macrophages. Clin Exp Immunol 85 : 531-535
25. McKenzie ANJ, Culpepper JA, Waal Malefyt R de, Briere F, Punnonen J, Aversa G, Sato A, Dang W, Cocks BG, Menon S, Vries JE de, Banchereau J, Zurawski G (1993) Interleukin-13, a T-cell-derived cytokine that regulates human monocyte and B-cell function. Proc Natl Acad Sci USA 90 : 3735-3739
26. Minty A, Chalon P, Derocq JM, Dumont X, Guilemot J-C, Kaghad M, Labit C, Leplatois P, Liauzun P, Miloux B, Minty C, Casellas P, Loison G, Lupker J, Shire D, Ferrara P, Caput D (1993) Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. Nature 362 : 248-250
27. Montaner LJ, Doyle AG, Collin M, Herbein G, Illei P, James W, Minty A, Caput D, Ferrara P, Gordon S (1993) Interleukin-13 inhibits human immunodeficiency virus type 1 production in primary blood-derived human macrophages in vitro. J Exp Med 178 : 743-747
28. Nestle FO, Turka LA, Nickoloff BJ (1994) Characterization of dermal dendritic cells in psoriasis. Autostimulation of T lymphcytes and induction of TH1 type cytokines. J Clin Invest 94 : 202-209
29. Oord van den JJ, Wolf-Peeters C de (1994) Epithelium-lining macrophages in psoriasis. Br J Dermatol 130 : 589-594
30. Paukkonen K, Naukkarinen A, Horsmanheimo M (1992) The development of manifest psoriatic lesions is linked with the invasion of CD8+ T cells and CD11c+ macrophages into the epidermis. Arch Dermatol Res 284 : 375-379
31. Pigatto PD, Pigatto LB, Bigardi A, Altomare G, Finzi AF (1990) Factors secreted by untreated psoriatic monocytes enhance neutrophil function. J Invest Dermatol 94 : 372-376
32. Prens EP, Benne K, Joost T van, Benner R (1991) The autologous mixed epidermal cell T lymphocyte reaction is elevated in psoriasis: a crucial role for epidermal HLA-DR+/CD1a- antigen-presenting cells. J Invest Dermatol 96 : 880-887
33. Prinz JC, Gross B, Vollmer S, Trommler P, Strobel I, Meurer M, Plewig G (1994) T cell clones from psoriasis skin lesions can promote kereatinocyte proliferation in vitro via secreted products. Eur J Immunol 24 : 593-598
34. Punnonen J, Aversa G, Cocks BG, McKenzie ANJ, Menon S, Zurawski G, Waal Malefyt R de, Vries JE de (1993) Interleukin-13 induces interleukin-4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc Natl Acad Sci USA 90 : 3730-3734
35. Rein G, Abraham A, Raychadauri SP, Weltman H (1994) Monocyte adhesion to fibronectin in psoriasis. Int J Dermatol 33 : 374-379
36. Rieger-Wettengl G, Castellucci M, Schulze H-J (1994) Subepidermal macrophages - a diagnostic marker for psoriasis versus psoriasiform dermatitis (abstract). Arch Dermatol Res 286 : 207
37. Sallusto F, Cella M, Danieli C, Lanzavecchia A (1995) Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J Exp Med 182 : 389-400
38. Santiago-Schwarz F, Belilos E, Diamond B, Carsons SE (1992) TNF in combination with GM-CSF enhances the differentiation of neonatal cord blood stem cells into dendritic cells and macrophages. J Leukoc Biol 52 : 274-281
39. Schlaak JF, Buslau M, Jochum W, Hermann E, Girndt M, Gallati H, Meyer zum Büschenfelde K-H, Fleischer B (1994) T cells involved in psoriasis vulgaris belong to the Th1 subset. J Invest Dermatol 102 : 145-149
40. Schmitt-Egenolf M, Boehncke W-H, Ständer M, Eiermann TH, Sterry W (1993) Oligonucleotide typing reveals association of type I psoriasis with the HLA-DRB1*0701/2, -DQ1*0201, -DQB1*0303 extended haplotype. J Invest Dermatol 100 : 749-752
41. Schopf RE, Dobmeyer J, Dobmeyer T, Morsches B (1993) Soluble CD14 monocyte antigen in suction blister fluid and serum of patients with psoriasis. Dermatology 186 : 45-49
42. Schubert C, Christophers E (1985) Mast cells and macrophages in early relapsing psoriasis. Arch Dermatol Res 277 : 352-358
43. Scott P (1993) IL-12: initiation cytokine for cell-mediated immunity. Science 260 : 496-497
44. Spiteri MA, Poulter LW (1991) Characterization of immune inducer and suppressor macrophages from the normal human lung. Clin Exp Immunol 83 : 157-162
45. Spiteri MA, Clarke SW, Poulter LW (1988) Phenotypic and functional changes in alveolar macrophages contribute to the pathogenesis of pulmonary sarcoidosis. Clin Exp Immunol 74 : 359-364
46. Stein M, Keshav S, Harris N, Gordon S (1992) Interleukin-4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J Exp Med 176 : 287-292
47. Sterry W, Boehnke W-H (1993) Phenotypic heterogeneity of the dermal monocyte/macrophage system. In: Nickoloff BJ (ed) Dermal immune system. CRC Press, Boca Raton, pp 67-89
48. Stingl G, Bergstresser PR (1995) Dendritic cells: a major story unfolds. Immunol Today 16 : 330-333
49. Strange P, Cooper KD, Hansen ER, Fisher G, Larsen JK, Fox D, Krag C, Voorhees JJ, Baadsgaard O (1993) T-lymphocyte clones initiated from lesional psoriatic skin release growth factors that induce keratinoyte proliferation. J Invest Dermatol 101 : 695-700
50. Tanaka M, Lee K, Yodoi J, Saito H, Iwai Y, Kim K-M, Morita M, Mayumi M, Mikawa H (1989) Regulation of FcεRII (CD23) expression on a human eosinophilic cell line EoL3 and a human monocytic cell line U937. Cell Immunol 122 : 96-107
51. Tomfohrde J, Silverman A, Barnes R, Fernandez-Vina MA, Young M, Lory D, Morris L, Wuepper KD, Stastny P, Menter A, Bowcock A (1994) Gene for familial psoriasis susceptibility mapped to the distal end of human chromosome 17q. Science 264 : 1141-1145
52. Uyemura K, Yamamura M, Fivenson DF, Modlin RL, Nickoloff BJ (1993) The cytokine network in lesional and lesion-free psoriatic skin is characterized by a T-helper type 1 cell-mediated response. J Invest Dermatol 101 : 701-705
53. Villanueva POF, Harris TS, Ricklan DE, Stadecker MJ (1994) Macrophages from schistosomal egg granulomas induce unresponsiveness in specific cloned Th-1 lymphocytes in vitro and down-regulate schistosomal granulomatous disease in vivo. J Immunol 152 : 1847-1855
54. Villanueva POF, Reiser H, Stadecker MJ (1994) Regulation of T helper cell responses in experimental murine schistosomiasis by IL-10. J Immunol 153 : 5190-5199
55. Vollmer S, Menssen A, Trommler P, Schendel D, Prinz JC (1994) T lymphocytes derived from skin lesions of patients with psoriasis vulgaris express a novel cytokine pattern that is distinct from that of T helper type 1 and T helper type 2 cells. Eur J Immunol 24 : 2377-2382
56. Waal Malefyt R de, Haanen J, Spits H, Roncarolo M-G, Velde A te, Figdor C, Johnson K, Kastelein R, Yssel H, Vries JE de (1991) Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J Exp Med 174 : 915-924
57. Walsh LJ, Goerdt S, Pober JS, Sueki H, Murphy GF (1991) MS-1 sinusoidal endothelial antigen is expressed by factor XIIIa+, HLA-DR+ dermal perivascular dendritic cells. Lab Invest 65 : 732-741
58. Weber-Matthiesen K, Sterry W (1990) Organisation of the monocyte/macrophage system of normal human skin. J Invest Dermatol 95 : 83-89
59. Wiseman DM, Polverini PJ, Kamp DW, Leibovich SJ (1988) Transforming growth factor-β is chemotactic for human monocytes and induces their expression of angiogenic activity. Biochem Biophys Res Commun 157 : 793-800
60. Wölfer L-U, Djemadji-Oudjiel N, Hiletework M, Tebbe B, Husak R, Goerdt S, Orfanos CE (1996) HIV-assoziierte Psoriasis. Klinische und histologische Beobachtungen an 36 Patienten. Hautzartz (in press)
61. Wölfer L-U, Goerdt S, Schröder K, Zouboulis CC, Orfanos E (1996) Interferon-γ-induzierte Psoriasis. Hautarzt 47 : 124-128
62. Zlotnik A, Moore KW (1992) Interleukin 10. Cytokine 3 : 366-371
63. Zurawski SM, Vega F Jr, Huyghe B, Zurawski G (1993) Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction. EMBO J 12 : 2663-2670
64. Zwadlo G, Bröcker EB, Bassewitz D-B von, Feige U, Sorg C (1985) A monoclonal antibody to a differentiation antigen present on mature human macrophages and absent from monocytes. J Immunol 134 : 1487-1492
65. Zwadlo G, Voegeli R, Schulze-Osthoff K, Sorg C (1987) A monoclonal antibody to a novel differentiation antigen on human macrophages associated with the down-regulatory phase of the inflammatory process. Exp Cell Biol 55 : 295-304
66. Zwadlo-Klarwasser G, Bent S, Haubeck H-D, Sorg C, Schmutzler W (1990) Glucocorticoid-induced appearance of the macrophage subtype RM 3/1 in peripheral blood in man. Int Arch Allergy Appl Immunol 91 : 175-180
67. Zwadlo-Klarwasser G, Bent S, Schmutzler W (1991) Comparison of dermal and systemic application of glucocorticoids on the RM 3/1+ macrophages in human blood. Int Arch Allergy Appl Immunol 94 : 278-279