A zinc chelator inhibiting gelatinases exerts potent in vitro anti-invasive effects

European Journal of Pharmacology

Volumn 351, Issue 2, 1998, Pages 225-233

  Ferry, Gilles ^a   Boutin, Jean A ^a   Hennig, Philippe ^a   Genton, Annie ^a   Desmet, Christine ^a   Fauchère, Jean Luc ^a   Atassi, Ghanem ^a   Tucker, Gordon C ^a  

^a INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

MMP 2; MMP 9; Zinc chelation; Zymography

Indexed keywords

BATIMASTAT; CHELATING AGENT; GELATINASE; MATRIX METALLOPROTEINASE INHIBITOR; N1 [2,2 DIMETHYL 1 [(METHYLAMINO)CARBONYL]PROPYL] N4 HYDROXY 2 (2 METHYLPROPYL)BUTANEDIAMIDE; UNCLASSIFIED DRUG; UNDECADENEDIOIC ACID BIS[[2 (3H IMIDAZOL 4 YL)ETHYL]AMIDE];

ANIMAL CELL; ARTICLE; BLADDER CARCINOMA; CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME INHIBITION; FIBROBLAST; FIBROSARCOMA; HUMAN; HUMAN CELL; LEWIS CARCINOMA; NONHUMAN; PRIORITY JOURNAL;

3T3 CELLS; ANIMALS; CHELATING AGENTS; FATTY ACIDS, UNSATURATED; GELATINASES; HISTAMINE; HYDROXAMIC ACIDS; IMIDAZOLES; METALLOENDOPEPTIDASES; MICE; MICE, INBRED BALB C; NEOPLASM INVASIVENESS; PHENYLALANINE; PROTEASE INHIBITORS; THIOPHENES; TUMOR CELLS, CULTURED; ZINC;

EID: 0031838562     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00304-5     Document Type: Article

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