Preconditioning with cortical spreading depression decreases intraischemic cerebral glutamate levels and down-regulates excitatory amino acid transporters EAAT1 and EAAT2 from rat cerebral cortex plasma membranes

Journal of Neurochemistry

Volumn 75, Issue 2, 2000, Pages 812-818

  Douen, Andre G ^a   Akiyama, Katsunori ^b   Hogan, Matthew J ^a   Wang, Fuhu ^a   Dong, Li ^a   Chow, Ava K ^a   Hakim, Antoine ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

^b TOKAI UNIVERSITY   (Japan)

Author keywords

Cerebral ischemia; Cortical spreading depression; Glutamate; Glutamate transporters; Neuroprotection; Preconditioning

Indexed keywords

EXCITATORY AMINO ACID; GLUTAMATE TRANSPORTER; NEUROTRANSMITTER;

AMINO ACID BRAIN LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; BRAIN MEMBRANE; CONDITIONING; CONTROLLED STUDY; DOWN REGULATION; GLIA CELL; MALE; NEUROPROTECTION; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT; SPREADING CORTICAL DEPRESSION;

AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CARRIER PROTEINS; CELL MEMBRANE; CEREBRAL ARTERIES; CEREBRAL CORTEX; EXCITATORY AMINO ACID TRANSPORTER 1; EXCITATORY AMINO ACID TRANSPORTER 2; EXCITATORY AMINO ACID TRANSPORTER 3; EXTRACELLULAR SPACE; FRONTAL LOBE; FUNCTIONAL LATERALITY; GLUTAMATE PLASMA MEMBRANE TRANSPORT PROTEINS; GLUTAMIC ACID; ISCHEMIC ATTACK, TRANSIENT; ISCHEMIC PRECONDITIONING; MALE; NEURONS; OCCIPITAL LOBE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROTRANSMITTER; SPREADING CORTICAL DEPRESSION; SYMPORTERS;

ANIMALIA;

EID: 0033929508     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0750812.x     Document Type: Article

References (34)

1. Chen J., Graham S. H., Zhu R. L., and Simon R. P. (1996) Stress proteins and tolerance to focal cerebral ischemia. J. Cereb. Blood Flow Metab. 16, 566-577.
2. Choi D. W. (1988) Glutamate neurotoxicity and diseases of the nervous system. Neuron 1, 623-634.
3. Douen A. G., Kacem R., and Jones M. N. (1988) Direct interaction of phenylarsine oxide with hexose transporters in isolated rat adipocytes. Biochim. Biophys. Acta 994, 445-450.
4. Douen A. G., Ramlal T., Rastogi S., Bilan P. J., Cartee G., Vranic M., Holloszy J. O., and Klip A. (1990) Exercise induces recruitment of the "insulin responsive glucose transporter." Evidence for distinct intracellular insulin- and exercise-recruitable transporter pools in skeletal muscles. J. Biol. Chem. 265, 13427-13430.
5. Dube G. R. and Marshall K. C. (1997) Modulation of excitatory synaptic transmission in locus coeruleus by multiple presynaptic metabotropic glutamate receptors. Neuroscience 80, 511-521.
6. Farrar J. K. (1987) Hydrogen clearance technique, in Cerebral Blood Flow - Physiologic and Clinical Aspects (Wood J. H., ed), pp. 275-287. McGraw-Hill, New York.
7. Ginsberg S. D., Martin L. J., and Rothstein J. D. (1995) Regional deafferentiation down-regulates subtypes of glutamate transporter proteins. J. Neurochem. 65, 2800-2803.
8. Glazier S., O'Rourke D. M., Graham D. I., and Welsh F. A. (1994) Induction of ischemic tolerance following brief focal ischemia in rat brain. J. Cereb. Blood Flow Metab. 14, 545-553.
9. Herdegen T., Sandkuhler J., Gass P., Kiessling M., Bravo R., and Zimmermann M. (1993) JUN, FOS, KROX and CREB transcription factor proteins in the rat cortex: basal expression and induction by spreading depression and epileptic seizures. J. Comp. Neurol. 333, 271-288.
10. Herrera D. G. and Robertson H. A. (1990) Application of potassium chloride to the brain surface induces the c-fos proto-oncogene: reversal by MK-801. Brain Res. 510, 166-170.
11. Kato H., Liu Y., Araki T., and Kogure K. (1991) Temporal profile of the effects of pretreatment with brief cerebral ischemia on the neuronal damage following secondary ischemic insult in the gerbil: cumulative damage and protective effects. Brain Res. 553, 238-242.
12. Kawahara N., Ruetzler C. A., and Klatzo I. (1995) Protective effect of spreading depression. Neurol. Res. 17, 9-16.
13. Kokaia Z., Gido G., Ringstedt G., Bengzon J., Kokaia M., Siesjö B. K., Persson H., and Lindvall O. (1993) Rapid increase of BDNF mRNA levels in cortical neurons following spreading depression: regulation by glutamatergic mechanisms independent of seizure activity. Mol. Brain Res. 19, 277-286.
14. Kraig R. P., Dong L., Thisted R., and Jaeger C. B. (1991) Spreading depression increases immunohistochemical staining of glial fibrillary acidic protein. J. Neurosci. 11, 2187-2198.
15. +-dependent glutamate transport. J. Neurosci. 19, RC16, 1-9.
16. Maki R., Robinson M. B., and Dichter M. A. (1994) The glutamate uptake inhibitor L-trans-pyrrolidine-2,4-dicarboxylate depresses excitatory synaptic transmission via a presynaptic mechanism in cultured hippocampal neurons. J. Neurosci. 14, 6754-6762.
17. Marette A., Burdette E., Douen A. G., Vranic M., and Klip A. (1992) Insulin induces the translocation of GLUT-4 glucose transporters from a unique intracellular organelle to transverse tubules in rat skeletal muscles. Diabetes 41, 1562-1569.
18. Matsushima K., Hogan M. J., and Hakim A. M. (1996a) Cortical spreading depression protects against subsequent focal cerebral ischemia in rats. J. Cereb. Blood Flow Metab. 16, 221-236.
19. Matsushima K., Schmidt-Kastner R., and Hakim A. M. (1996b Spreading depression may protect from subsequent ischemic damage by increasing expression of neurotrophic factors. Brain Res. 807, 47-60.
20. Matsushima K., Schmidt-Kastner R., Hogan M. J., and Hakim A. M. (1998) Cortical spreading depression activates trophic factor expression in neurons and astrocytes and protects against subsequent focal brain ischemia. Brain Res. 807, 47-60.
21. Nicholls D. and Attwell D. (1990) The release and uptake of excitatory amino acids. Trends Pharmacol. Sci. 11, 462-468.
22. Osuga H. and Hakim A. M. (1994) Relevance of interstitial glutamate to selective vulnerability in focal cerebral ischemia. J. Cereb. Blood Flow Metab. 14, 343-347.
23. Osuga H. and Hakim A. M. (1996) Relationship between extracellular glutamate concentration and voltage-sensitive calcium channel function in focal cerebral ischemia in the rat. J. Cereb. Blood Flow Metab. 16, 629-636.
24. 3H]nimodipine into brain during cortical spreading depression. J. Cereb. Blood Flow Metab. 17, 586-590.
25. Raghavendra Rao V. L., Baskaya M. K., Doǧan A., Rothstein J. D., and Dempsey R. J. (1998) Traumatic brain injury down-regulates glial glutamate transporter (GLT-1 and GLAST) proteins in rat brain. J. Neurochem. 70, 2020-2027.
26. Robinson S. E. (1999) Inhibition of ischemia-induced glutamate release in rat striatum by dihydrokainate and anion channel blocker. Stroke 30, 440.
27. Rothstein J. D. (1996) Excitotoxic hypothesis. Neurology 47 (Suppl.), S19-S26.
28. Rothstein J. D., Dykes-Hoberg M., Pardo C. A., Bristol L. A., Jin L., Kuncl R. W., Kanai Y., Hediger M. A., Wang Y., Schielke J. P., and Welty D. F. (1996) Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron 16, 675-686.
29. 3H]-D-aspartate from primary astrocyte cultures in response to raised external potassium. J. Neurosci. 16, 7803-7811.
30. Seki Y., Feustel P. J., Keller R. W., Tranmer B. I., and Kimelberg H. K. (1999) Inhibition of ischemia-induced glutamate release in rat striatum by dihydrokainate and anion channel blocker. Stroke 30, 433-440.
31. Siesjö B. K. (1994) Calcium-mediated processes in neurodegeneration. Ann. NY Acad. Sci. 747, 140-161.
32. Szatkowski M. and Attwell D. (1994) Triggering an execution of neuronal death in brain ischemia: two phases of glutamate release by different mechanisms. Trends Neurosci. 17, 359-365.
33. Taga K., Patel P. M., Drummond J. C., Cole D. J., and Kelly P. J. (1997) Transient neuronal depolarization induces tolerance to subsequent forebrain ischemia in rats. Anesthesiology 87, 918-925.
34. Zea Longa E. Z., Weinstein P. R., Carlson S., and Cummins R. (1989) Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20, 84-91.