Modulation of excitatory synaptic transmission in locus coeruleus by multiple presynaptic metabotropic glutamate receptors

Neuroscience

Volumn 80, Issue 2, 1997, Pages 511-521

  Dube G R ^a   Marshall, K C ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Excitatory postsynaptic potentials; L AP4; Locus coeruleus; Metabotropic glutamate receptor; Presynaptic; t ACPD

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 2 AMINO 2 METHYL 4 PHOSPHONOBUTYRIC ACID; 2 AMINO 4 PHOSPHONOBUTYRIC ACID; 3,5 DIHYDROXYPHENYLGLYCINE; 4 AMINOPYRROLIDINE 2,4 DICARBOXYLIC ACID; 4 CARBOXY 3 HYDROXYPHENYLGLYCINE; ALPHA METHYL 4 CARBOXYPHENYLGLYCINE; AMINOINDAN DICARBOXYLIC ACID; BUTYRIC ACID DERIVATIVE; DICARBOXYLIC ACID DERIVATIVE; GLUTAMIC ACID; METABOTROPIC RECEPTOR; PRESYNAPTIC RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; LOCUS CERULEUS; MALE; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTIC TRANSMISSION;

AMINOBUTYRIC ACIDS; ANIMALS; CYCLOLEUCINE; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACIDS; LOCUS COERULEUS; MALE; MEMBRANE POTENTIALS; NEUROTOXINS; NEUROTRANSMITTER AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 0030751330     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(97)00004-3     Document Type: Article

References (71)

1. Aston-Jones G., Akaoka H., Charléty P. J. and Chouvet G. (1991) Serotonin selectively attenuates glutamate-evoked activation of noradrenergic locus coeruleus neurons. J. Neurosci. 11, 760-769.
2. Aston-Jones G., Ennis M., Pieribone V. A., Nickell W. T. and Shipley M. T. (1986) The brain nucleus locus coeruleus: restricted afferent control of a broad efferent network. Science 234, 734-737.
3. Baskys A. and Malenka R. C. (1991) Agonists at metabotropic glutamate receptors presynaptically inhibit EPSCs in neonatal rat hippocampus. J. Physiol. Lond. 444, 687-701.
4. Baude A., Nusser Z., Roberts J. D. B., Mulvihill E., McIlhinney R. A. J. and Somogyi P. (1993) The metabotropic glutamate receptor (mGluR1α) is concentrated at presynaptic membrane of neuronal subpopulations as detected by immunogold reaction. Neuron 11, 771-787.
5. Burke J. P. and Hablitz J. J. (1994) Presynaptic depression of synaptic transmission mediated by activation of metabotropic glutamate receptors in rat neocortex. J. Neurosci. 14, 5120-5130.
6. Bushell T. J., Jane D. E., Tse H.-W., Watkins J. C., Davies C. H., Garthwaite J. and Collingridge G. L. (1995) Antagonism of the synaptic depressant actions of L-AP4 in the lateral perforant path by MAP4. Neuropharmacology 34, 239-241.
7. Bushell T. J., Jane D. E., Tse H. W., Watkins J. C., Garthwaite J. and Collingridge G. L. (1996) Pharmacological antagonism of the actions of group II and III mGluR agonists in the lateral perforant path of rat hippocampal slices. Br. J. Pharmac. 117, 1457-1462.
8. Calabresi P., Pisani A., Mercuri N. B. and Bernardi G. (1993) Heterogeneity of metabotropic glutamate receptors in the striatum: electrophysiological evidence. Eur. J. Neurosci. 5, 1370-1377.
9. Charléty P. J., Chergui K., Akaoka H., Saunier C. F., Buda M., Aston-Jones G. and Chouvet G. (1993) Serotonin differentially modulates responses mediated by specific excitatory amino acid receptors in the rat locus coeruleus. Eur. J. Neurosci. 5, 1024-1028.
10. Chavis P., Fagni L., Lansman J. B. and Bockaert J. (1996) Functional coupling between ryanodine receptors and L-type calcium channels in neurons. Nature 382, 719-722.
11. Chavis P., Nooney J. M., Bockaert J., Fagni L., Feltz A. and Bossu J. L. (1995) Facilitatory coupling between a glutamate metabotropic receptor and dihydropyridine-sensitive calcium channels in cultured cerebellar granule cells. J. Neurosci. 15, 135-143.
12. Cherubini E., North R. A. and Williams J. T. (1988) Synaptic potentials in rat locus coeruleus neurones. J. Physiol. Lond. 406, 431-442.
13. Cotman C. W., Flatman J. A., Ganong A. H. and Perkins M. H. (1986) Effects of excitatory amino acid antagonists on evoked and spontaneous excitatory potentials in guinea-pig hippocampus. J. Physiol. Lond. 378, 403-415.
14. Crépel F., Daniel H., Hémart N. and Jaillard D. (1991) Effects of ACPD and AP3 on parallel-fibre-mediated EPSPs of Purkinje cells in cerebellar slices in vitro. Expl Brain Res. 86, 402-406.
15. Desai M. A. and Conn P. J. (1991) Excitatory effects of ACPD receptor activation in the hippocampus are mediated by direct effects on pyramidal cells and blockade of synaptic inhibition. J. Neurophysiol. 66, 40-52.
16. Desai M. A., McBain C. J., Kauer J. A. and Conn P. J. (1994) Metabotropic glutamate receptor-induced disinhibition is mediated by reduced transmission at excitatory synapses onto interneurons and inhibitory synapses onto pyramidal cells. Neurosci. Lett. 181, 78-82.
17. East S. J. and Garthwaite J. (1992) Actions of a metabotropic glutamate receptor agonist in immature and adult rat cerebellum. Eur. J. Pharmac. 219, 395-400.
18. Ennis M. and Aston-Jones G. (1988) Activation of locus coeruleus from nucleus paragigantocellularis: a new excitatory amino acid pathway in brain. J. Neurosci. 8, 3644-3657.
19. Ennis M. and Aston-Jones G. (1989) Potent inhibitory input to locus coeruleus from the nucleus prepositus hypoglossi. Brain Res. Bull. 22, 793-803.
20. Ennis M., Aston-Jones G. and Shiekhattar R. (1992) Activation of locus coeruleus neurons by nucleus paragigantocellularis or noxious sensory stimulation is mediated by intracoerulear excitatory amino acid neurotransmission. Brain Res. 598, 185-195.
21. Gereau R. W. and Conn P. J. (1995) Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1. J. Neurosci. 15, 6879-6889.
22. Gereau R. W. and Conn P. J. (1995) Roles of specific metabotropic glutamate receptor subtypes in regulating hippocampal CA1 pyramidal cell excitability. J. Neurophysiol. 74, 122-129.
23. Glaum S. R. and Miller R. J. (1993) Activation of metabotropic glutamate receptors produces reciprocal regulation of ionotropic glutamate and GABA responses in the nucleus of the tractus solitarius of the rat. J. Neurosci. 13, 1636-1641.
24. Glaum S. R. and Miller R. J. (1993) Metabotropic glutamate receptors depress afferent excitatory transmission in the rat nucleus tractus solitarii. J. Neurophysiol. 70, 2669-2672.
25. Glaum S. R. and Miller R. J. (1995) Presynaptic metabotropic glutamate receptors modulate omega-conotoxin-GVIA-insensitive calcium channels in the rat medulla. Neuropharmacology 34, 953-964.
26. Harris E. W. and Cotman C. W. (1983) Effects of acidic amino acid antagonists on paired-pulse potentiation at the lateral perforant path. Expl Brain Res. 52, 455-460.
27. Hayashi Y., Sekiyama N., Nakanishi S., Jane D. E., Sunter D. C., Birse E. F., Udvarhelyi P. M. and Watkins J. C. (1994) Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes. J. Neurosci. 14, 3370-3377.
28. Ivanov A. and Aston-Jones G. (1995) Extranuclear dendrites of locus coeruleus neurons: activation by glutamate and modulation of activity by alpha adrenoceptors. J. Neurophysiol. 74, 2427-2436.
29. Jane D. E., Jones P. L., Pook P. C., Tse H. W. and Watkins J. C. (1994) Actions of two new antagonists showing selectivity for different sub-types of metabotropic glutamate receptor in the neonatal rat spinal cord. Br. J. Pharmac. 112, 809-816.
30. Jane D. E., Pittaway K., Sunter D. C., Thomas N. K. and Watkins J. C. (1995) New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord. Neuropharmacology 34, 851-856.
31. Kemp M., Roberts P., Pook P., Jane D., Jones A., Jones P., Sunter D., Udvarhelyi P. and Watkins J. (1994) Antagonism of presynaptically mediated depressant responses and cyclic AMP-coupled metabotropic glutamate receptors. Eur. J. Pharmac. 266, 187-192.
32. Kinzie J. M., Saugstad J. A., Westbrook G. L. and Segerson T. P. (1995) Distribution of metabotropic glutamate receptor 7 messenger RNA in the developing and adult rat brain. Neuroscience 69, 167-176.
33. Liu Y. B., Disterhoft J. F. and Slater N. T. (1993) Activation of metabotropic glutamate receptors induces long-term depression of GABAergic inhibition in hippocampus. J. Neurophysiol. 69, 1000-1004.
34. Lovinger D. M. and McCool B. A. (1995) Metabotropic glutamate receptor-mediated presyanptic depression at corticostriatal synapses involves mGluR2 or 3. J. Neurosci. 73, 1076-1083.
35. Marshall K. C. and Xiong H. G. (1991) Modulation of amino-acid neurotransmitter actions by other neurotransmitters - some examples. Can. J. Physiol. Pharmac. 69, 1115-1122.
36. Martin L. J., Blackstone C. D., Huganir R. L. and Price D. L. (1992) Cellular localization of a metabotropic glutamate receptor in rat brain. Neuron 9, 259-270.
37. Masuko S., Nakajima Y., Nakajima S. and Yamaguchi K. (1986) Noradrenergic neurons from the locus ceruleus in dissociated cell culture: culture methods, morphology, and electrophysiology. J. Neurosci. 6, 3229-3241.
38. Nakajima Y., Iwakabe H., Akazawa C., Nawa H., Shigemoto R., Mizuno N. and Nakanishi S. (1993) Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate. J. biol. Chem. 268, 11868-11873.
39. Nakanishi S. (1992) Molecular diversity of glutamate receptors and implications for brain function. Science 258, 597-603.
40. Nakanishi S. (1994) Metabotropic glutamate receptors: synaptic transmission, modulation, and plasticity. Neuron 13, 1031-1037.
41. Nusser Z., Mulvihill E., Streit P. and Somogyi P. (1994) Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization. Neroscience 61, 421-427.
42. Ohishi H., Shigemoto R., Nakanishi S. and Mizuno N. (1993) Distribution of the mRNA for a metabotropic glutamate receptor (mGluR3) in the rat brain: an in situ hybridization study. J. comp. Neurol. 335, 252-266.
43. Okamoto N., Hori S., Akazawa C., Hayashi Y., Shigemoto R., Mizumo N. and Nakanishi S. (1994) Molecular characterization of a new metabotropic glutamate receptor, mGluR7, coupled to inhibitory cyclic AMP signal transduction. J. biol. Chem. 269, 1231-1236.
44. Oleskevich S., Clements J. D. and Williams J. T. (1993) Opioid-glutamate interactions in rat locus coeruleus neurons. J. Neurophysiol. 70, 931-937.
45. Olpe H. R., Steinmann M. W., Brugger F. and Pozza M. F. (1989) Excitatory amino acid receptors in rat locus coeruleus. An extracellular in vitro study. Naunyn Schmiedebergs Arch. Pharmac. 339, 312-314.
46. Pellicciari R., Luneia R., Costantino G., Marinozzi M., Natalini B., Jakobsen P., Kanstrup A., Lombardi G., Moroni F. and Thomsen C. (1995) 1-Aminoindan-1,5-dicarboxylic acid: a novel antagonist at phospholipase C-linked metabotropic glutamate receptors. J. med. Chem. 38, 3717-3719.
47. Petralia R. S., Wang Y. X., Niedzielski A. S. and Wenthold R. J. (1996) The metabotropic glutamate receptors, mGluR2 and mGluR3, show unique postsynaptic, presynaptic and glial localizations. Neuroscience 71, 949-976.
48. Pin J. P. and Duvoisin R. (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34, 1-26.
49. Poncer J.-C., Shinozaki H. and Miles R. (1995) Dual modulation of synaptic inhibition by distinct metabotropic glutamate receptors in the rat hippocampus. J. Physiol. Lond. 485, 121-134.
50. Rainnie D. G. and Shinnick-Gallagher P. (1992) Trans-ACPD and L-APB presynaptically inhibit excitatory glutamatergic transmission in the basolateral amygdala (BLA). Neurosci. Lett. 139, 87-91.
51. Roberts P. J. (1995) Pharmacological tools for the investigation of metabotropic glutamate receptors (mGluRs): phenylglycine derivatives and other selective antagonists - an update. Neuropharmacology 34, 813-819.
52. Romano C., Sesma M. A., McDonald C. T., O'Malley K., Van den Pol A. N. and Olney J. W. (1995) Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain. J. comp. Neurol. 355, 455-469.
53. Sahara Y. and Westbrook G. L. (1993) Modulation of calcium currents by metabotropic glutamate receptor involves fast and slow kinetic components in cultured hippocampal neurons. J. Neurosci. 13, 3041-3050.
54. Salt T. E. and Eaton S. A. (1995) Modulation of sensory neurone excitatory and inhibitory responses in the ventrobasal thalamus by activation of metabotropic excitatory amino acid receptors. Neuropharmacology 34, 1043-1051.
55. Salt T. E. and Eaton S. A. (1995) Distinct presynaptic metabotropic receptors for L-AP4 and CCG1 on gabaergic terminals: pharmacological evidence using novel α-methyl derivatives mGluR antagonists, MAP4 and MCCG, in the rat thalamus in vitro. Neuroscience 65, 5-13.
56. Saugstad J. A., Kinzie J. M., Mulvihill E. R., Segerson T. P. and Westbrook G. L. (1994) Cloning and expression of a new member of the L-2-amino-4-phosphonobutyric acid-sensitive class of metabotropic glutamate receptors. Molec. Pharmac. 45, 367-372.
57. Sayer R. J., Schwindt P. C. and Crill W. E. (1992) Metabotropic glutamate receptor-mediated suppression of L-type calcium current in acutely isolated neocortical neurons. J. Neurophysiol. 68, 833-842.
58. Schoepp D. D., Johnson B. G., Salhoff C. R., Valli M. J., Desai M. A., Burnett J. P., Mayne N. G. and Monn J. A. (1995) Selective inhibition of forskolin-stimulated cyclic AMP formation in rat hippocampus by a novel mGluR agonist, 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate. Neuropharmacology 34, 843-850.
59. Schoepp D. D., Salhoff C. R., Wright R. A., Johnson B. G., Burnett J. P., Mayne N. G., Belagaje R., Wu S. and Monn J. A. (1996) The novel metabotropic glutamate receptor agonist 2R,4R-APDC potentiates stimulation of phosphoinositide hydrolysis in the rat hippocampus by 3,5-dihydroxyphenylglycine: evidence for a synergistic interation between group 1 and group 2 receptors. Neuropharmacology 35, 1661-1672.
60. Stuart G. J. and Redman S. J. (1991) Mechanism of presynaptic inhibition studied using paired-pulse facilitation. Neurosci. Lett. 126, 179-183.
61. Swartz K. J. and Bean B. P. (1992) Inhibition of calcium channels in rat CA3 pyramidal neurons by a metabotropic glutamate receptor. J. Neurosci. 12, 4358-4371.
62. Takahashi T., Forsythe I. D., Tsujimoto T., Barnes-Davis M. and Onodera K. (1996) Presynaptic calcium current modulation by a metabotropic glutamate receptor. Science 274, 594-597.
63. Tanabe Y., Nomura A., Masu M., Shigemoto R., Mizumo N. and Nakanishi S. (1993) Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGlu3 and mGluR4. J. Neurosci. 13, 1372-1378.
64. Thomas N. K., Jane D. E., Tse H. W. and Watkins J. C. (1996) (S)-α-Ethylglutamic acid and (AS)-α-cyclopropyl-4-phosphonophenylglycine as antagonists of L-AP4 and (1S,3S)-ACPD-induced depression of monosynaptic excitation of neonatal rat motoneurons. Br. J. Pharmac. 117, P70.
65. Thomas N. K., Jane D. E., Tse H.-W. and Watkins J. C. (1995) Serine-O-phosphate derivatives as novel, potent and selective metabotropic glutamate receptor antagonists. Soc. Neurosci. Abstr. 21.
66. Thomsen C., Kristensen P., Mulvihill E., Haldeman B. and Suzdak P. D. (1992) L-2-Amino-4-phosphonobutyrate (L-AP4) is an agonist at the type IV metabotropic glutamate receptor which is negatively coupled to adenylate cyclase. Eur. J. Pharmac. 227, 361-362.
67. Travagli R. A., Dunwiddie T. V. and Williams J. T. (1995) Opioid inhibition in locus coeruleus. J. Neurophysiol. 74, 518-528.
68. Watkins J. and Collingridge G. (1994) Phenylglycine derivatives as antagonists of metabotropic glutamate receptors. Trends pharmac. Sci. 15, 333-342.
69. Williams J. T., Bobker D. H. and Harris G. C. (1991) Synaptic potentials in locus coeruleus neurons in brain slices. Prog. Brain Res. 88, 167-172.
70. Xiong H. and Marshall K. C. (1994) Angiotensin II depresses glutamate depolarizations and excitatory postsynaptic potentials in locus coeruleus through angiotensin II subtype 2 receptors. Neuroscience 62, 163-175.
71. Yoshino M. and Kamiya H. (1995) Suppression of presynaptic calcium influx by metabotropic glutamate receptor agonists in neonatal rat hippocampus. Brain Res. 695, 179-185.