Telencephalic transplants in mice: Characterization of growth and differentiation patterns

Neuropathology and Applied Neurobiology

Volumn 22, Issue 2, 1996, Pages 108-117

  Isenmann, S ^a,b   Brandner, S ^a   Sure, U ^a   Aguzzi, A ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

CNS development; Degeneration; Differentiation; Immunocytochemistry; Neural transplantation (mice); Proliferation; Transgenic mice

Indexed keywords

BROXURIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN TRANSPLANTATION; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; GRAFT SURVIVAL; IMMUNOCYTOCHEMISTRY; ISOTOPE LABELING; LATERAL BRAIN VENTRICLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TELENCEPHALON; TIME; TRANSGENIC ANIMAL;

EID: 0029877026     PISSN: 03051846     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2990.1996.tb00854.x     Document Type: Article

References (30)

1. Aguzzi A, Brandner S, Sure U, Ruedi D, Isenmann S. Transgenic and knock-out mice: models of neurological disease. Brain Pathol 1994; 4: 3-20
2. Aguzzi A, Kleihues P, Heckl K, Wiestler OD. Cell type-specific tumor induction in neural transplants by retrovirus-mediated oncogene transfer. Oncogene 1991; 6: 113-8
3. Bhattacharya A, Dorf ME, Springer TA. A shared allo-antigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I-region gene duplication. J Immunol 1981; 127: 2488-95
4. Bladt F, Riethmacher D, Isenmann S, Aguzzi A, Birchmeier C. The c-met receptor is essential for migration of myogenic precursor cells into the anlage of the limb. Nature 1995; 376: 768-77
5. Broadwell RD, Charlton HM, Ebert P, Hickey WF, Villegas JC, Wolf AL. Angiogenesis and the blood-brain barrier in solid and dissociated cell grafts within the CNS. Prog Brain Res 1990; 82: 95-101
6. Brüstle O, Aguzzi A, Talarico D, Basilico C, Kleihues P, Wiestler OD. Angiogenic activity of the K-fgf/hst oncogene in neural transplants. Oncogene 1992; 7: 117-83
7. Büeler H, Aguzzi A, Sailer A et al. Mice devoid of PrP are resistant to scrapie. Cell 1993; 73: 1339-47
8. Dunnett SB. Neural transplantation in animal models of dementia. Eur J Neurosci 1990; 2: 567-87
9. Dunnett SB, Bjorklund A, Stenevi U, Iversen SD. Grafts of embryonic substantia nigra reinnervating the ventrolateral striatum ameliorate sensorimotor impairments and akinesia in rats with 6-OHDA lesion of the nigrostriatal pathway. Brain Res 1981; 229: 209-17
10. Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981; 154-6
11. Fisher LJ, Gage FH. Grafting in the mammalian central nervous system. Physiol Rev 1993; 73: 583-616
12. Fisher LJ, Ray J. In vivo and ex vivo gene transfer to the brain. Curr Opin Neurobiol 1994; 4: 735-41
13. Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear dna fragmentation. J Cell Biol 1992; 119: 493-501
14. Gratzner HG. Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication. Science 1982; 218: 474-5
15. Isenmann S, Brandner S, Kühne G, Boner J, Aguzzi A. Comparative in vivo and pathological analysis of the blood-brain barrier in mouse telencephalic transplants. Neuropathol Appl Neurobiol 1996; 22: 118-28
16. Isenmann S, Molthagen M, Brandner S et al. The AMOG/β2 Subunit of the Na, K-ATPase is not Necessary for Long-term Survival of Telencephalic Grafts. Glia 1995; 15: 377-88
17. Jaeger CB, Lund RD. Transplantation of embryonic occipital cortex to the brain of newborn rats. An autoradiographic study of transplant histogenesis. Exp Brain Res 1980; 40: 265-72
18. Kromer LF, Björklund A, Stenevi U. Intracephalic implants: a technique for studying neuronal interactions. Science 1979; 204: 1117-9
19. Krum JM, Rosenstein JM. Patterns of angiogenesis in neural transplant models: II. Fetal neocortical transplants. J Comp Neurol 1988; 271: 331-45
20. Leigh K, Elisevich K, Rogers KA. Vascularization and microvascular permeability in solid vs. cell-suspension embryonic grafts. J Neurosurg 1994; 81: 272-83
21. Magyar JP, Bartsch U, Wang Z-Q, Howells N, Aguzzi A, Wagner EF, Schachner M. Degeneration of Neural Cells in the Central Nervous System of Mice Deficient in the Gene for the Adhesion Molecule on Glia, the β2 Subunit of Murine Na, K-ATPase. J Cell Biol 1994; 127: 135-46
22. Marion DW, Pollack IF, Lund RD. Patterns of immune rejection of mouse neocortex transplanted into neonatal rat brain, and effects of host immunosuppression. Brain Res 1990; 519: 133-43
23. Perry VH, Hume DA, Gordon S. Immunohistochemical localisation of macrophages and microglia in the developing mouse brain. Neuroscience 1985; 15: 313-26
24. Renfranz PJ, Cunningham MG, McKay RDG. Region-specific differentiation of the hippocampal stem cell line HiB5 upon implantation into the developing mammalian brain. Cell 1991; 68: 713-29
25. Richards SJ, Waters JJ, Beyreuther K, Masters CL, Wischik CM, Sparkman DR, White CL, III, Abraham CR, Dunnett SB. Transplants of mouse trisomy 16 hippocampus provide a model of Alzheimer's disease neuropathology. EMBO-J 1991; 10: 297-303
26. Streit WJ, Graeber MB, Kreutzberg GW. Functional plasticity of microglia: a review. Glia 1988; 1: 301-7
27. Thomas KR, Capecchi MR. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 1987; 51: 503-12
28. Widner H, Brundin P. Immunological aspects of grafting in the mammalian central nervous system. A review and speculative synthesis. Brain Res Rev 1988; 13: 287-324
29. Wiestler OD, Aguzzi A, Schneemann M, Eibl R, von DA, Kleihues P. Oncogene complementation in fetal brain transplants. Cancer Res 1992; 52: 3760-7
30. Wiestler OD, Brüstle O, Eibl RH, Radner H, Aguzzi A, Kleihues P. Retrovirus-mediated oncogene transfer into neural transplants. Brain Pathol 1992; 2: 47-59