Adenoviral vector-mediated gene transfer and neurotransplantation: Possibilities and limitations in grafting of the fetal rat suprachiasmatic nucleus

Journal of Neuroscience Methods

Volumn 71, Issue 1, 1997, Pages 113-123

  Van Esseveldt, K E ^a   Liu, R ^a   Hermens, W T J M C ^a,b   Verhaagen, J ^a,b   Boer, G J ^a  

^a NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

adenoviral vector; ex vivo gene transfer; neurotransplantation; suprachiasmatic nucleus; vasoactive intestinal polypeptide

Indexed keywords

VASOACTIVE INTESTINAL POLYPEPTIDE;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; GENE TRANSFER; IMMUNOHISTOCHEMISTRY; NERVE TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; RAT; SUPRACHIASMATIC NUCLEUS;

ADENOVIRIDAE; ANIMALS; BETA-GALACTOSIDASE; BRAIN TISSUE TRANSPLANTATION; DEFECTIVE VIRUSES; FETAL TISSUE TRANSPLANTATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE THERAPY; GENES, REPORTER; GENETIC VECTORS; PARKINSON DISEASE; RATS; RATS, WISTAR; RECOMBINANT FUSION PROTEINS; SUPRACHIASMATIC NUCLEUS; TRANSFECTION;

EID: 0030906597     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0270(96)00131-8     Document Type: Article

References (48)

1. Aguilar-Roblero, R., Shibata, S., Speh, J.C., Drucker-Colin, R. and Moore, R.Y., (1992) Morphological and functional development of the suprachiasmatic nucleus in transplanted fetal hypothalamus, Brain Res., 580: 288-296.
2. Akli, S., Caillaud, C., Vigne, E., Stratford-Perricaudet, L.D., Perricaudet, M. and Peschanski, M.R. (1993) Transfer of a foreign gene into the brain using adenovirus vectors, Nat. Genet., 3: 224-228.
3. Bajocchi, G., Feldman, S.H., Crystal, R.G. and Mastrangeli, A. (1993) Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors, Nat. Genet., 3: 229-234.
4. Björklund, A. (1992) Dopaminergic transplants in experimental parkinsonism: cellular mechanisms of graft-induced functional recovery, Curr. Opin. Neurobiol., 2: 683-689.
5. Björklund, A. and Stenevi, U. (1979) Reconstruction of the nigrostriatal dopamine pathway by intracerebral nigral transplants, Brain Res., 177: 555-560.
6. Boer, G.J., Dozy, M.H. and Uylings, H.B.M, (1984) Cerebellar DNA and tissue water changes in the brain of diabetes insipidus Brattleboro rats are already present at birth, Int. J. Dev. Neurosci., 2: 301-304.
7. Boer, G.J., Gash, D.M., Dick, L. and Schluter, N. (1985) Vasopressin neuron survival in neonatal Brattleboro rats; critical factors in graft development and innervation of the host brain, Neuroscience, 15: 1087-1109.
8. Boer, G.J, and Griffioen, H.A. (1990) Developmental and functional aspects of grafting of the suprachiasmatic nucleus in the Brattleboro and the arhythmic rat, Eur. J. Morphol., 28: 330-345.
9. Boer, G.J., Griffioen, H.A., Duindam, H., Van der Woude, T.P. and Rietveld, W.J. (1993) Light/dark-induced effects on behavioral rhythms in suprachiasmatic nucleus lesioned rats irrespective of the presence of functional suprachiasmatic nucleus brain implants, J. Interdiscipl. Cycle Res., 24: 118-136.
10. Buijs, R.M., Pool, C.W., Heerikhuize, J.J., Sluiter, A.A., Van de Sluis, P.J., Ramkema, M., Van der Woude, T.P. and Van der Beek, E. (1990) Antibodies to small transmitter molecules and peptides: production and application of antibodies to dopamine, serotonine, GABA, vasopressin, vasoactive intestinal polypeptide, neuropeptide Y, somatostatin and substance P, Biomed. Res., 10: 213-221.
11. Byrnes, A.P., Rusby, J.E., Wood, M.J.A. and Charlton, H.M. (1995) Adenovirus gene transfer causes inflammation in the brain, Neuroscience, 66: 1015-1024.
12. Caillaud, C., Akli, S., Vigne, E., Koulakoff, A., Perricaudet, M., Poenaru, L., Kahn, A. and Berwald-Netter, Y. (1993) Adenoviral vector as a gene delivery system into cultured rat neuronal and glial cells, Eur. J. Neurosci., 5: 1287-1291.
13. Dai, Y., Schwarz, E.M., Gu, D., Zhang, W., Sarvetnick, N. and Verma, I.M. (1995) Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression, Proc. Natl. Acad. Sci. USA, 92: 1401-1405.
14. Davidson, B.L., Allen, E.D., Kozarsky, K.F., Wilson, J.M. and Roessler, B.J. (1993) A model system for in vivo gene transfer into the central nervous system using an adenoviral vector, Nat. Genet., 3: 219-223.
15. Doering, L.C. (1994) Nervous system modification by transplants and gene transfer, Bioessays, 16: 825-831.
16. During, M.J., Naegele, J.R., O'Malley, K.L. and Geller, A.I. (1994) Long-term behavioral recovery in Parkinsonian rats by an HSV vector expressing tyrosine hydroxylase, Science, 266: 1399-1403.
17. Fallaux, F.J., Kranenburg, O., Cramer, S.J., Houweling, A., Van Ormandt, H., Hoeben, R.C. and Van der Eb, A.J. (1996) Characterization of 911: a new helper cell line for the titration and propagation of early-region-1-deleted adenoviral vectors, Hum. Gene Ther., 7: 215-222.
18. Fisher, L.J., Jinnah, H.A., Kale, L.C., Higgins, G.A. and Gage, F.H. (1991) Survival and function of intrastriatally grafted primary fibroblasts genetically modified to produce L-DOPA, Neuron, 6: 371-380.
19. Freed, C.R., Breeze, R.E., Rosenberg, N.L., Schneck, S.A., Kriek, E., Qi, J., Lone, T., Zhang, Y., Snyder, J.A., Wells, T.H., Ramig, L.O., Thompson, L., Mazziotta, J.C., Huang, S.C., Grafton, S.T., Brooks, D., Sawle, G., Schroter, G. and Ansari, A.A. (1992) Survival of implanted fetal dopamine cells and neurological improvement 12 to 46 months after transplantation in Parkinson's disease, N. Engl. J. Med., 327: 1549-1555.
20. Frim, D.M., Uhler, T.A., Galpern, W.R., Beal, M.F., Breakefield, X.O. and Isacson, O. (1994) Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent l-methyl-4-phenyl-phenylpyridinium toxicity to dopaminergic neurons in the rat, Proc. Natl. Acad. Sci. USA, 91: 5104-5108.
21. Gash, D.M., Bresjanac, M., Junn, F. and Zhang, Z. (1994) Trophic mechanisms mediating functional recovery following intrastriatal implantation. In S.B. Dunnett and A. Björklund (Eds.), Functional Neural Transplantation, Raven Press, New York, pp. 139-156.
22. Griffioen, H.A., Van der Beek, E. and Boer, G.J. (1992) Gelatin embedding to preserve lesion-damaged hypothalami and intracerebroventricular grafts for vibratome slicing and immunocytochemistry, J. Neurosci. Methods, 43: 43-47.
23. Griffioen, H.A., Duindam, H., Van der Woude, T.P., Rietveld, W.J. and Boer G.J. (1993) Functional development of fetal suprachiasmatic nucleus grafts in suprachiasmatic nucleus-lesioned rats, Brain Res. Bull., 31: 145-160.
24. Hermens, W.T.J.M.C., Giger, R.J., Holtmaat, A.J.G.D., Dijkhuizen, P.A., Houweling, D., Wolswijk, G. and Verhaagen, J. (1997) Efficient in vitro and in vivo gene transfer to neurons and analysis of adenoviral vector performance in the CNS and PNS, J. Neurosci. Methods, 71: 85-98.
25. Horellou, P., Brundin, P., Kalén, P., Mallet, J. and Björklund, A. (1990) In vivo release of DOPA and dopamine from genetically engineered cells grafted to the denervated rat striatum, Neuron, 5: 393-402.
26. Horellou, P., Vigne, E., Castel, M.-N., Barnéoud, P., Colin, P., Perricaudet, M., Delaère, P. and Mallet, J. (1994) Direct intracerebral gene transfer of an adenoviral vector expressing tyrosine hydroxylase in a rat model of Parkinson's disease, Neuroreport, 6: 49-53.
27. Hou, J.-G.G., Lin, L.-F.H. and Mytilineou, C (1996) Glial cell line-derived neurotrophic factor exerts neurotrophic effects on dopaminergic neurons in vitro and promotes their survival and regrowth after damage by 1-methyl-4-phenylpyridinium, J. Neurochem., 66: 74-82.
28. Kaplitt, M.G., Leone, P., Samulski, R.J., Xiao, X., Pfaff, D.W., O'Malley, K.L. and During, M.J. (1994) Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain, Nat. Genet., 8: 148-154.
29. Kay, M.A., Holterman, A.-X., Meuse, L., Gown, A., Ochs, H.D., Linsley, P.S. and Wilson, C.B. (1995) Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administration, Nat. Genet., 11: 191-197.
30. Kordower, J.H., Freeman, T.B., Snow, B.J., Vingerhoets, F.J.G., Mufson, E.J., Sanberg, P.R., Hauser, R.A., Smith, D.A., Nauert, G.M., Perl, D.P. and Olanow, C.W. (1995) Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with parkinson's disease, N. Engl. J. Med., 332: 1118-1124.
31. Le Gal La Salle, G., Robert, J.J., Berrard, S., Ridoux, V., Sratford-Perricaudet, L.D., Perricaudet, M. and Mallet, J. (1993) An adenovirus vector for gene transfer into neurons and glia in the brain, Science, 259: 988-990.
32. Lehman, M.N., Silver, R., Gladstone, W.R., Kahn, R.M., Gibson, M. and Bittman, E.L. (1987) Circadian rhythmicity restored by neural transplant. Immunocytochemical characterization of the graft and its integration with the host brain, J. Neurosci., 7: 1626-1638.
33. Levivier, M., Przedborski, S., Bencsics, C. and Jung kang, U. (1995) Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's Disease, J. Neurosci., 15: 7810-7820.
34. Lindvall, O. (1989) Transplantation into the human brain: present status and future possibilities, J. Neurol. Neurosurg. Psychiatr., S39-54.
35. Lindvall, O., Brundin, P., Widner, H., Rehncrona, S., Gustavii, B., Frackowiak, R., Leenders, K.L., Sawle, G., Rothwell, J.C., Marsden C.D. and Björklund, A. (1990) Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease, Science, 247: 574-577.
36. Lowenstein, P.R., Bain, D., Shering, A.F., Wilkinson, G.W.G. and Castro, M.G. (1995) Cell type-specific expression from viral promoters within replication-deficient adenovirus recombinants in primary neocortical cultures, Restor. Neurol. Neurosci., 8: 37-39.
37. Neuwelt, E.A., Pagel, M.A., Geller, A. and Muldoon, L.L. (1995) Gene replacement therapy in the central nervous system: viral vector-mediated therapy of global neurodegenerative disease, Behav. Brain. Sci., 18: 1-9.
38. Perlow, M.J., Freed, W.J., Hoffer, B.J., Seiger, A., Olson, L. and Wyatt, R.J. (1979) Brain grafts reduce motor abnormalities produced by destruction of nigrostriatal dopamine system, Science, 204: 643-647.
39. Peschanski, M., Defer, G., N'Guyen, J.P., Ricolfi, F., Monfort, J.C., Remy, P., Geny, C., Samson, Y., Hantraye, P., Jeny, R., Gaston, A., Kéravel, Y., Degos, J.D. and Cesaro, P. (1994) Bilateral motor improvement and alteration of L-DOPA effect in two patients with Parkinson's disease following intrastriatal transplantation of foetal ventral mesencephalon, Brain, 117: 487-499.
40. Ralph, M.R., Foster, R.G., Davis, F.C. and Menaker, M. (1990) Transplanted suprachiasmatic nucleus determines circadian period, Science, 247: 975-978.
41. Ridoux, V., Robert, J.J., Zhang, X., Perricaudet, M., Mallet, J. and Le Gal La Salle, G. (1994) The use of adenovirus vectors for intracerebral grafting of transfected nervous cells, Neuroreport, 5: 801-804.
42. Romijn, H.J., De Jong, B.M. and Ruijter, J.M. (1988) A procedure for culturing rat neocortex explants in a serum-free nutrient medium, J. Neurosci. Methods, 23: 75-83.
43. Sabaté, O., Horellou, P., Vigne, E., Colin, P., Perricaudet, M., Buc-Caron, M.-H. and Mallet, J. (1995) Transplantation to the rat brain of human neural progenitors that were genetically modified using adenoviruses, Nat. Genet., 9: 256-260.
44. Scharfmann, R., Axelrod, J.H. and Verma, I.M. (1991) Long-term in vivo expression of retrovirus-mediated gene transfer in mouse fibroblast implants, Proc. Natl. Acad. Sci. USA, 88: 4626-4630.
45. Sollars, P.J. and Pickard, G.E. (1995) Vasoactive intestinal peptide efferent projections of the suprachiasmatic nucleus in anterior hypothalamic transplants: correlation with functional restoration of circadian behavior, Exp. Neurol., 136: 1-11.
46. Takayama, H., Ray, J., Raymon, H.K., Baird, A., Hogg, J., Fisher, L.J. and gage, F.H. (1995) Basic fibroblast growth factor increases dopaminergic graft survival and function in a rat model of Parkinson's disease, Nat. Med., 1: 53-58.
47. Wiegand, S.J. and Gash, D.M. (1988) Organization and efferent connections of transplanted suprachiasmatic nuclei, J. Comp. Neurol., 267: 562-579.
48. Wilkemeyer, M.F. and Angelides, K.J. (1995) Adenovirus-mediated expression of a reporter gene in thalamocortical cocultures, Brain Res., 703: 129-138.