AIDS vaccines: Heterologous prime/boost strategies for raising protective T cell responses

AIDS Reviews

Volumn 2, Issue 2, 2000, Pages 105-110

  Robinson, H L ^a   Smith, J M ^a   Rao, A R ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

DNA vaccine; HIV 1 vaccine; Recombinant pox virus vaccine

Indexed keywords

CD8 ANTIGEN; DNA VACCINE; RECOMBINANT VACCINE;

ANTIGEN RECOGNITION; DRUG EFFICACY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOSTIMULATION; REVIEW; T LYMPHOCYTE;

EID: 0033915386     PISSN: 11396121     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (31)

1. Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA
2. Prognosis in HIV-1 infection predicted by the quantity of virus in plasma
3. Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes
4. Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia
5. CD8+ lymphocytes can control HIV infection in vitro by suppressing virus replication
6. Controlling HIV pathogenesis: The role of the noncytotoxic anti-HIV response of CD8+ T cells
7. Viral dynamics in HIV-1 infection
8. CD8+ T cell-mediated suppressive activity inhibits HIV-1 after virus entry with kinetics indicating effects on virus gene expression
9. Antigen-driven C-C chemokine-mediated HIV-1 suppression by CD4(+) T cells from exposed uninfected individuals expressing the wild-type CCR-5 allele
10. Production of beta-chemokines in human immunodeficiency virus (HIV) infection: Evidence that high levels of macrophage inflammatory protein-1beta are associated with a decreased risk of HIV disease progression
11. Multifactorial nature of noncytolytic CD8+ T cell-mediated suppression of HIV replication: Beta-chemokine-dependent and -independent effects
12. Epidemiological and immunological implications of the global variability of HIV-1
13. Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef.
14. Counting antigen-specific CD8 T cells: A reevaluation of bystander activation during viral infection
15. Persistence of memory CD8 T cells in MHC class I-dificient mice
16. Induction of CD8+ T cells using heterologous prime-boost immunisation strategies
17. Host range restricted, non-replicating vaccinia virus vectors as vaccine candidates
18. Mapping of deletions in the genome of the highly attenuated vaccinia virus MVA and their influence on virulence
19. Augmentation of immune responses to HIV-1 and simian immunodeficiency virus DNA vaccines by IL-2/lg plasmid administration in rhesus monkeys
20. Effective induction of simian immunodeficiency virus-specific cytotoxic T lymphocytes in macaques by using a multiepitope gene and DNA prime-modified vaccinia virus Ankara boost vaccination regimen
21. Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization
22. Induction of genital immunity by DNA priming and intranasal booster immunization with a replication-defective adenoviral recombinant
23. Neutralizing antibody-independent containment of immunodeficiency virus challenges by DNA priming and recombinant pox virus booster Immunization
24. Enhanced T-cell immunogenicity and protective efficacy of a human immunodeficiency virus type 1 vaccine regimen consisting of consecutive priming with DNA and boosting with recombinant fowlpox virus
25. Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara
26. Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine
27. Enhancement of MHC class I-restricted peptide-specific T cell induction by a DNA prime/MVA boost vaccination regime
28. Cytokine enhancement of DNA immunization leads to effective treatment of established pulmonary metastases
29. Influenza and vaccinia viruses expressing malaria CD8+ T and B cell epitopes. Comparison of their immunogenicity and capacity to induce protective immunity
30. Characterization of in vivo primary and secondary CD8+ T cell responses induced by recombinant influenza and vaccinia viruses
31. Priming with recombinant influenza virus followed by administration of recombinant vaccinia virus induces CD8+ T-cell-mediated protective immunity against malaria