메뉴 건너뛰기




Volumn 15, Issue 8, 2000, Pages 1545-1554

Cytokines and bone loss in a 5-year longitudinal study hormone replacement therapy suppresses serum soluble interleukin-6 receptor and increases interleukin-1-receptor antagonist: The Danish Osteoporosis Prevention Study

Author keywords

Bone mineral density; Cytokines; Hormone replacement therapy; Interleukin 6; Menopause

Indexed keywords

CYTOKINE; ESTRADIOL; FOLLITROPIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 6 RECEPTOR; NORETHISTERONE ACETATE;

EID: 0033915371     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2000.15.8.1545     Document Type: Article
Times cited : (87)

References (56)
  • 1
    • 0027252772 scopus 로고
    • The effects of menopause on longitudinal bone loss from the spine
    • Pouilles JM Tremollieres F, Ribot C 1993 The effects of menopause on longitudinal bone loss from the spine. Calcif Tissue Int 52:340-343.
    • (1993) Calcif Tissue Int , vol.52 , pp. 340-343
    • Pouilles, J.M.1    Tremollieres, F.2    Ribot, C.3
  • 2
    • 0025339574 scopus 로고
    • Estrogen treatment of patients with established postmenopausal osteoporosis
    • Lindsay R, Tohme JF 1990 Estrogen treatment of patients with established postmenopausal osteoporosis. Obstet Gynecol 76: 290-295.
    • (1990) Obstet Gynecol , vol.76 , pp. 290-295
    • Lindsay, R.1    Tohme, J.F.2
  • 3
    • 0025360635 scopus 로고
    • Long-term estrogen replacement therapy in postmenopausal women sustains vertebral bone mineral density
    • Moore M, Bracker, M Sartoris D, Saltman P, Strause L 1990 Long-term estrogen replacement therapy in postmenopausal women sustains vertebral bone mineral density. J Bone Miner Res 5:659-664.
    • (1990) J Bone Miner Res , vol.5 , pp. 659-664
    • Moore, M.1    Bracker, M.2    Sartoris, D.3    Saltman, P.4    Strause, L.5
  • 4
    • 0028363006 scopus 로고
    • Magnitude and pattern of skeletal response to long term continous and cyclic sequential oestrogen/progestin treatment
    • Nielsen SP, Bärenholdt O, Hermansen F, Munk-Jensen N 1994 Magnitude and pattern of skeletal response to long term continous and cyclic sequential oestrogen/progestin treatment. Br Obstet Gynaecol 101:319-324.
    • (1994) Br Obstet Gynaecol , vol.101 , pp. 319-324
    • Nielsen, S.P.1    Bärenholdt, O.2    Hermansen, F.3    Munk-Jensen, N.4
  • 5
    • 0029783770 scopus 로고    scopus 로고
    • Estrogen, cytokines, and pathogenesis of postmenopausal osteoporosis
    • Pacifici R 1996 Estrogen, cytokines, and pathogenesis of postmenopausal osteoporosis. J Bone Miner Res 11:1043-1051.
    • (1996) J Bone Miner Res , vol.11 , pp. 1043-1051
    • Pacifici, R.1
  • 6
    • 0028925088 scopus 로고
    • Bone marrow, cytokines and bone remodeling
    • Manolagas SC, Jilka RL 1995 Bone marrow, cytokines and bone remodeling. N Engl J Med 332:305-311.
    • (1995) N Engl J Med , vol.332 , pp. 305-311
    • Manolagas, S.C.1    Jilka, R.L.2
  • 7
    • 0032494113 scopus 로고    scopus 로고
    • TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts
    • Fuller K, Wong B, Fox S. Choi Y, Chambers TJ 1998 TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts. J Exp Med 188: 997-1001.
    • (1998) J Exp Med , vol.188 , pp. 997-1001
    • Fuller, K.1    Wong, B.2    Fox, S.3    Choi, Y.4    Chambers, T.J.5
  • 8
    • 0032145401 scopus 로고    scopus 로고
    • Cytokines, bone remodelling, and estrogen deficiency: A 1998 update
    • Jilka RL 1998 Cytokines, bone remodelling, and estrogen deficiency: A 1998 update. Bone 23:75-81.
    • (1998) Bone , vol.23 , pp. 75-81
    • Jilka, R.L.1
  • 10
    • 0025021471 scopus 로고
    • Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist
    • Eisenberg SP, Evans RJ, Arend WP, Verdeerber E, Brewer, MT, Hannum CH, Thompson RC 1990 Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist. Nature 343:341-346.
    • (1990) Nature , vol.343 , pp. 341-346
    • Eisenberg, S.P.1    Evans, R.J.2    Arend, W.P.3    Verdeerber, E.4    Brewer, M.T.5    Hannum, C.H.6    Thompson, R.C.7
  • 14
    • 0026516415 scopus 로고
    • 17 beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: A potential mechanism for the antiosteoporotic effect of estro-gens
    • Girasole G, Jilka R, Passeri G, Boswell S, Boder G, Williams D, Manolagas S 1992 17 beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: A potential mechanism for the antiosteoporotic effect of estro-gens. J Clin Invest 89:883-891.
    • (1992) J Clin Invest , vol.89 , pp. 883-891
    • Girasole, G.1    Jilka, R.2    Passeri, G.3    Boswell, S.4    Boder, G.5    Williams, D.6    Manolagas, S.7
  • 15
    • 0030020568 scopus 로고    scopus 로고
    • Estrogen inhibits interleukin-6 production and gene expression in a human osteoblastic cell line with high levels of estrogen receptors
    • Kassem M, Harris SA, Spelsberg TC, Riggs BL 1996 Estrogen inhibits interleukin-6 production and gene expression in a human osteoblastic cell line with high levels of estrogen receptors. J Bone Miner Res 11:193-199.
    • (1996) J Bone Miner Res , vol.11 , pp. 193-199
    • Kassem, M.1    Harris, S.A.2    Spelsberg, T.C.3    Riggs, B.L.4
  • 16
    • 0030064975 scopus 로고    scopus 로고
    • Cytokine production in the bone marrow microenvironment: Failure to demonstrate estrogen regulation in early postmenopausal women
    • Kassem M Khosla S, Spelsberg TC, Riggs BL 1996 Cytokine production in the bone marrow microenvironment: Failure to demonstrate estrogen regulation in early postmenopausal women. J Clin Endocrinol Metab 81:513-518.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 513-518
    • Kassem, M.1    Khosla, S.2    Spelsberg, T.C.3    Riggs, B.L.4
  • 18
    • 0031667369 scopus 로고    scopus 로고
    • Effects of estrogen therapy of postmenopausal women on cytokines measured in peripheral blood
    • Rogers A, Eastell R 1998 Effects of estrogen therapy of postmenopausal women on cytokines measured in peripheral blood. J Bone Miner Res 13:1577-1586.
    • (1998) J Bone Miner Res , vol.13 , pp. 1577-1586
    • Rogers, A.1    Eastell, R.2
  • 19
    • 0013215653 scopus 로고
    • Increased serum soluble interleukin-6 receptor levels are induced by ovariectomy, prevented by estrogen replacement and reversed by alendronate administration
    • abstract
    • Girasole G, Pedrazzoni M, Giuliani N, Passeri G, Passeri M 1995 Increased serum soluble interleukin-6 receptor levels are induced by ovariectomy, prevented by estrogen replacement and reversed by alendronate administration. J Bone Miner Res 10:S161 (abstract).
    • (1995) J Bone Miner Res , vol.10
    • Girasole, G.1    Pedrazzoni, M.2    Giuliani, N.3    Passeri, G.4    Passeri, M.5
  • 20
    • 0013226930 scopus 로고
    • Serum level of soluble interleukin 6 receptor, not interleukin 6, is correlated with bone resorption markers and lumbar bone mineral density after menopause
    • abstract
    • Chen JT, Maruo N, Kato T, Hasumi K, Ogata E, Shiraki M, Morita I 1995 Serum level of soluble interleukin 6 receptor, not interleukin 6, is correlated with bone resorption markers and lumbar bone mineral density after menopause. J Bone Miner Res 10(Suppl 1):M378 (abstract).
    • (1995) J Bone Miner Res , vol.10 , Issue.SUPPL. 1
    • Chen, J.T.1    Maruo, N.2    Kato, T.3    Hasumi, K.4    Ogata, E.5    Shiraki, M.6    Morita, I.7
  • 21
    • 0342573845 scopus 로고    scopus 로고
    • Serum level of soluble interleukin 6 receptor is correlated with the change of bone metabolism during estrogen therapy
    • abstract
    • Maruo N, Chen JT, Ogata E, Shiraki M, Morita I 1996 Serum level of soluble interleukin 6 receptor is correlated with the change of bone metabolism during estrogen therapy. J Bone Miner Res 11(Suppl 1):S118 (abstract).
    • (1996) J Bone Miner Res , vol.11 , Issue.SUPPL. 1
    • Maruo, N.1    Chen, J.T.2    Ogata, E.3    Shiraki, M.4    Morita, I.5
  • 22
    • 0028088001 scopus 로고
    • Circulating levels of cytokines that modulate bone resorption: Effects of age and menopause in women
    • McKane WR, Khosla S, Peterson JM, Egan K, Riggs BL 1994 Circulating levels of cytokines that modulate bone resorption: Effects of age and menopause in women. J Bone Miner Res 9:1313-1318.
    • (1994) J Bone Miner Res , vol.9 , pp. 1313-1318
    • McKane, W.R.1    Khosla, S.2    Peterson, J.M.3    Egan, K.4    Riggs, B.L.5
  • 23
    • 0027423242 scopus 로고
    • Monocytic secretion of interleukin-1 receptor antagonist in normal and osteoporotic women: Effects of menopause and estrogen/ progesterone therapy
    • Pacifici R, Vannice JL, Rifas L, Kimble RB 1993 Monocytic secretion of interleukin-1 receptor antagonist in normal and osteoporotic women: Effects of menopause and estrogen/ progesterone therapy. J Clin Endocrinol Metab 77:1135-1141.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1135-1141
    • Pacifici, R.1    Vannice, J.L.2    Rifas, L.3    Kimble, R.B.4
  • 25
    • 15644370220 scopus 로고    scopus 로고
    • Use of postmenopausal hormone replacement therapy: Estimates from a nationally representative cohort study
    • Brett KM, Madans JH 1997 Use of postmenopausal hormone replacement therapy: Estimates from a nationally representative cohort study. Am J Epidemiol 145:536-545.
    • (1997) Am J Epidemiol , vol.145 , pp. 536-545
    • Brett, K.M.1    Madans, J.H.2
  • 26
    • 0028245512 scopus 로고
    • Analysis of gene expression in human bone biopsies by polymerase chain reaction: Evidence for enhanced cytokine expression in postmenopausal osteoporosis
    • Ralston SH 1994 Analysis of gene expression in human bone biopsies by polymerase chain reaction: Evidence for enhanced cytokine expression in postmenopausal osteoporosis. J Bone Miner Res 9:883-890.
    • (1994) J Bone Miner Res , vol.9 , pp. 883-890
    • Ralston, S.H.1
  • 31
    • 0030997301 scopus 로고    scopus 로고
    • Cytokines and T-lymphocyte subsets in healthy postmenopausal women: Estrogen retards bone loss without affecting the release of IL-1 or IL-1ra
    • Abrahamsen B, Bendtzen K, Beck-Nielsen H 1997 Cytokines and T-lymphocyte subsets in healthy postmenopausal women: Estrogen retards bone loss without affecting the release of IL-1 or IL-1ra. Bone 20:251-258.
    • (1997) Bone , vol.20 , pp. 251-258
    • Abrahamsen, B.1    Bendtzen, K.2    Beck-Nielsen, H.3
  • 33
    • 0028151432 scopus 로고
    • Interleukin-1 receptor antagonist and tumor necrosis factor binding protein decrease osteoclast formation and bone resorption in ovariectomized mice
    • Kitazawa R, Kimble RB, Vannice JL, Kung VT, Pacifici R 1994 Interleukin-1 receptor antagonist and tumor necrosis factor binding protein decrease osteoclast formation and bone resorption in ovariectomized mice. J Clin Invest 94:2397-2406.
    • (1994) J Clin Invest , vol.94 , pp. 2397-2406
    • Kitazawa, R.1    Kimble, R.B.2    Vannice, J.L.3    Kung, V.T.4    Pacifici, R.5
  • 34
    • 0032189033 scopus 로고    scopus 로고
    • Allelic variation at the Interleukin-1 receptor antagonist gene is associated with early postmenopausal hone loss at the spine
    • Keen RW, Woodford-Richens KL, Lanchbury JS, Spector TD 1998 Allelic variation at the Interleukin-1 receptor antagonist gene is associated with early postmenopausal hone loss at the spine. Bone 23:367-371.
    • (1998) Bone , vol.23 , pp. 367-371
    • Keen, R.W.1    Woodford-Richens, K.L.2    Lanchbury, J.S.3    Spector, T.D.4
  • 35
    • 0028179743 scopus 로고
    • Increased PGE2 from human monocytes isolated in the luteal phase of the menstrual cycle. Implications for immunity?
    • Leslie CA, Dubey DP 1994 Increased PGE2 from human monocytes isolated in the luteal phase of the menstrual cycle. Implications for immunity? Prostaglandins 47:41-54.
    • (1994) Prostaglandins , vol.47 , pp. 41-54
    • Leslie, C.A.1    Dubey, D.P.2
  • 36
    • 0025190282 scopus 로고
    • Cultured human luteal peripheral monocytes secrete increased levels of interleukin-1
    • Polan ML, Kuo A, Loukides J, Bottomly K 1990 Cultured human luteal peripheral monocytes secrete increased levels of interleukin-1. J Clin Endocrinol Metab 70:480-484.
    • (1990) J Clin Endocrinol Metab , vol.70 , pp. 480-484
    • Polan, M.L.1    Kuo, A.2    Loukides, J.3    Bottomly, K.4
  • 39
    • 0030960403 scopus 로고    scopus 로고
    • The functional block of TNF but not of IL-6 prevents bone loss in ovariectomized mice
    • Kimble RB, Bain S, Pacifici R 1997 The functional block of TNF but not of IL-6 prevents bone loss in ovariectomized mice. J Bone Miner Res 12:935-941.
    • (1997) J Bone Miner Res , vol.12 , pp. 935-941
    • Kimble, R.B.1    Bain, S.2    Pacifici, R.3
  • 40
    • 0029147741 scopus 로고
    • Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and C/EBP beta
    • Stein B, Yang MX 1995 Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and C/EBP beta. Mol Cell Biol 15:4971-4979.
    • (1995) Mol Cell Biol , vol.15 , pp. 4971-4979
    • Stein, B.1    Yang, M.X.2
  • 41
    • 0028031990 scopus 로고
    • Interleukin-6 (IL-6) as an anti-inflammatory cytokine: Induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55
    • Tilg H, Trehu E, Atkins MB, Dinarello CA, Mier JW 1994 Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55. Blood 83:113-118.
    • (1994) Blood , vol.83 , pp. 113-118
    • Tilg, H.1    Trehu, E.2    Atkins, M.B.3    Dinarello, C.A.4    Mier, J.W.5
  • 42
    • 0032518415 scopus 로고    scopus 로고
    • IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses
    • Xing Z, Gauldie J, Cox G, Baumann H, Jordana M, Lei XF, Achong MK 1998 IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses. J Clin Invest 101:311-320.
    • (1998) J Clin Invest , vol.101 , pp. 311-320
    • Xing, Z.1    Gauldie, J.2    Cox, G.3    Baumann, H.4    Jordana, M.5    Lei, X.F.6    Achong, M.K.7
  • 44
    • 0030850624 scopus 로고    scopus 로고
    • Site of osteodensitometry in perimenopausal women: Correlation and limits of agreement between anatomic regions
    • Abrahamsen B, Hansen TB, Jensen LB, Hermann AP, Eiken P 1997 Site of osteodensitometry in perimenopausal women: Correlation and limits of agreement between anatomic regions. J Bone Miner Res 12:1471-1479.
    • (1997) J Bone Miner Res , vol.12 , pp. 1471-1479
    • Abrahamsen, B.1    Hansen, T.B.2    Jensen, L.B.3    Hermann, A.P.4    Eiken, P.5
  • 45
    • 0030997237 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF)-I, -II, IGF binding proteins (IGFBP)-3,-4 and -5 levels in the conditioned media of normal human bone cells are skeletal site-dependent
    • Malpe R, Baylink DJ, Linkhart TA, Wergedal JE, Mohan S 1997 Insulin-like growth factor (IGF)-I, -II, IGF binding proteins (IGFBP)-3,-4 and -5 levels in the conditioned media of normal human bone cells are skeletal site-dependent. J Bone Miner Res 12:423-430.
    • (1997) J Bone Miner Res , vol.12 , pp. 423-430
    • Malpe, R.1    Baylink, D.J.2    Linkhart, T.A.3    Wergedal, J.E.4    Mohan, S.5
  • 47
    • 0031777442 scopus 로고    scopus 로고
    • Is parathyroid hormone a therapeutic option for osteoporosis? A review of the clinical evidence
    • Cosman F, Lindsay R 1998 Is parathyroid hormone a therapeutic option for osteoporosis? A review of the clinical evidence. Calcif Tissue Int 62:475-480.
    • (1998) Calcif Tissue Int , vol.62 , pp. 475-480
    • Cosman, F.1    Lindsay, R.2
  • 48
    • 0030686513 scopus 로고    scopus 로고
    • Changes in bone mass and serum markers of bone metabolism after parathyroidectomy
    • Thorsen K, Kristoffersson AO, Lorentzon RP 1997 Changes in bone mass and serum markers of bone metabolism after parathyroidectomy. Surgery 122:882-887.
    • (1997) Surgery , vol.122 , pp. 882-887
    • Thorsen, K.1    Kristoffersson, A.O.2    Lorentzon, R.P.3
  • 50
    • 0023946106 scopus 로고
    • Reversal of postmenopausal vertebral bone loss by oestrogen and progestogen: A double blind placebo controlled study
    • Munk-Jensen N, Nielsen SP, Obel EB, Eriksen PB 1988 Reversal of postmenopausal vertebral bone loss by oestrogen and progestogen: A double blind placebo controlled study. BMJ 296:1150-1152.
    • (1988) BMJ , vol.296 , pp. 1150-1152
    • Munk-Jensen, N.1    Nielsen, S.P.2    Obel, E.B.3    Eriksen, P.B.4
  • 51
    • 0024500027 scopus 로고
    • Effects of estrogen in vivo and in vitro on spontaneous interleukin-1 release by monocytes from postmenopausal women
    • Stock JL, Coderre JA, McDonald B, Rosenwasser LJ 1989 Effects of estrogen in vivo and in vitro on spontaneous interleukin-1 release by monocytes from postmenopausal women. J Clin Endocrinol Metab 68:364-368.
    • (1989) J Clin Endocrinol Metab , vol.68 , pp. 364-368
    • Stock, J.L.1    Coderre, J.A.2    McDonald, B.3    Rosenwasser, L.J.4
  • 53
    • 0027434307 scopus 로고
    • Cytokine production and surface antigen expression by peripheral blood mononuclear cells in postmenopausal osteoporosis
    • Hustmyer FG, Walker E, Yu XP, Girasole G, Sakagami Y, Peacock M, Manolagas SC 1993 Cytokine production and surface antigen expression by peripheral blood mononuclear cells in postmenopausal osteoporosis. J Bone Miner Res 8:51-59.
    • (1993) J Bone Miner Res , vol.8 , pp. 51-59
    • Hustmyer, F.G.1    Walker, E.2    Yu, X.P.3    Girasole, G.4    Sakagami, Y.5    Peacock, M.6    Manolagas, S.C.7
  • 55
    • 0028978461 scopus 로고
    • There is no difference in spontaneous and 17 beta-estradiol-induced interleukin-1 beta release by peripheral blood mononuclear cells from nonosteoporotic women with different rates of early postmenopausal bone loss
    • Hogasen AK, Nordsletten L, Aasen AO, Falch JA 1995 There is no difference in spontaneous and 17 beta-estradiol-induced interleukin-1 beta release by peripheral blood mononuclear cells from nonosteoporotic women with different rates of early postmenopausal bone loss. J Clin Endocrinol Metab 80:2480-2484.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 2480-2484
    • Hogasen, A.K.1    Nordsletten, L.2    Aasen, A.O.3    Falch, J.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.