메뉴 건너뛰기




Volumn 12, Issue 8, 2000, Pages 1218-1224

IL-12 elispot assays to detect and enumerate IL-12 secreting cells

Author keywords

Cytokines; ELISPOT; Flow cytometry; IL 12

Indexed keywords

CYTOKINE; ENDOTOXIN; GAMMA INTERFERON; INTERLEUKIN 12; LIPOPOLYSACCHARIDE; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

EID: 0033864919     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.2000.0696     Document Type: Article
Times cited : (12)

References (23)
  • 3
    • 0032536447 scopus 로고    scopus 로고
    • An interleukin-10/IL-12 Immunoregulatory circuit controls susceptibility to autoimmune disease
    • Segal BM, Dwyer BK, Shevach E. An interleukin-10/IL-12 Immunoregulatory circuit controls susceptibility to autoimmune disease. J Exp Med. 187:1998;537-546.
    • (1998) J Exp Med , vol.187 , pp. 537-546
    • Segal, B.M.1    Dwyer, B.K.2    Shevach, E.3
  • 5
    • 0024467154 scopus 로고
    • Identification and purification of natural killer cell stimulatory factor (NKSF) a cytokine with multiple biologic effects on human lymphocytes
    • Kobayashi M, Fitz L, Ryan M, Hewick RM, Clark SC, Chang S, Loudon R, Sherman F, Perussia B, Trinchieri G. Identification and purification of natural killer cell stimulatory factor (NKSF) a cytokine with multiple biologic effects on human lymphocytes. J Exp Med. 170:1989;827-845.
    • (1989) J Exp Med , vol.170 , pp. 827-845
    • Kobayashi, M.1    Fitz, L.2    Ryan, M.3    Hewick, R.M.4    Clark, S.C.5    Chang, S.6    Loudon, R.7    Sherman, F.8    Perussia, B.9    Trinchieri, G.10
  • 6
    • 0033120525 scopus 로고    scopus 로고
    • Expression of murine IL-12 is regulated by translational control of the p35 subunit
    • Babik JM, Adams E, Tone Yukiko, Fairchild PJ, Tone M, Waldmann H. Expression of murine IL-12 is regulated by translational control of the p35 subunit. J Immunol. 162:1999;4069-4078.
    • (1999) J Immunol , vol.162 , pp. 4069-4078
    • Babik, J.M.1    Adams, E.2    Tone Yukiko3    Fairchild, P.J.4    Tone, M.5    Waldmann, H.6
  • 7
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinchieri G. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu Rev Immunol. 13:1995;251-276.
    • (1995) Annu Rev Immunol , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 8
    • 0028943066 scopus 로고
    • Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon gamma and tumor necrosis factor alpha
    • Flesch IE, Hess JH, Huang S, Anguet M, Rothe J, Bluetmann H, Kaufmann SH. Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon gamma and tumor necrosis factor alpha. J Exp Med. 181:1995;1615-1621.
    • (1995) J Exp Med , vol.181 , pp. 1615-1621
    • Flesch, I.E.1    Hess, J.H.2    Huang, S.3    Anguet, M.4    Rothe, J.5    Bluetmann, H.6    Kaufmann, S.H.7
  • 9
    • 0029847274 scopus 로고    scopus 로고
    • Soluble tumor necrosis factor receptor inhibits interleukin 12 production by stimulated human adult microglial cells in vitro
    • Becher B, Dodelet V, Fedorowics V, Antel JP. Soluble tumor necrosis factor receptor inhibits interleukin 12 production by stimulated human adult microglial cells in vitro. J Clin Invest. 98:1996;1539-1543.
    • (1996) J Clin Invest , vol.98 , pp. 1539-1543
    • Becher, B.1    Dodelet, V.2    Fedorowics, V.3    Antel, J.P.4
  • 10
    • 85046498319 scopus 로고    scopus 로고
    • Measurements of serum cytokines
    • Barnes A. Measurements of serum cytokines. Lancet. 352:1998;324.
    • (1998) Lancet , vol.352 , pp. 324
    • Barnes, A.1
  • 11
    • 0033556352 scopus 로고    scopus 로고
    • Inhibition of Th1 polarization by soluble TNF receptor is dependent on antigen-presenting cell-derived IL-12
    • Becher B, Blain M, Giacomini PS, Antel JP. Inhibition of Th1 polarization by soluble TNF receptor is dependent on antigen-presenting cell-derived IL-12. J Immunol. 162:1999;684-688.
    • (1999) J Immunol , vol.162 , pp. 684-688
    • Becher, B.1    Blain, M.2    Giacomini, P.S.3    Antel, J.P.4
  • 13
    • 0031800907 scopus 로고    scopus 로고
    • Interleukin-12 and perforin mRNA expression is augmented in blood mononuclear cells in multiple sclerosis
    • Matusevicius D, Kivisäkk P, Navikas V, Soderstrom M, Fredrikson S, Link H. Interleukin-12 and perforin mRNA expression is augmented in blood mononuclear cells in multiple sclerosis. Scand J Immunol. 47:1998;582-590.
    • (1998) Scand J Immunol , vol.47 , pp. 582-590
    • Matusevicius, D.1    Kivisäkk, P.2    Navikas, V.3    Soderstrom, M.4    Fredrikson, S.5    Link, H.6
  • 14
    • 0032528896 scopus 로고    scopus 로고
    • Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy
    • Comabella M, Balashov K, Issazadeh S, Smith D, Weiner HL, Khoury S. Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy. J Clin Invest. 102:1998;671-678.
    • (1998) J Clin Invest , vol.102 , pp. 671-678
    • Comabella, M.1    Balashov, K.2    Issazadeh, S.3    Smith, D.4    Weiner, H.L.5    Khoury, S.6
  • 15
    • 0033490502 scopus 로고    scopus 로고
    • Interleukin 12: A cytokine at the interface of inflammation and immunity
    • Trinchieri G. Interleukin 12: a cytokine at the interface of inflammation and immunity. Adv Immunol. 70:1998;83-243.
    • (1998) Adv Immunol , vol.70 , pp. 83-243
    • Trinchieri, G.1
  • 16
    • 0021020342 scopus 로고
    • A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells
    • Czerkinsky CC, Nilsson LÅ, Nygren H, Ouchterlony Ö, Tarkowski A. A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells. J Immunol Meth. 65:1983;109-121.
    • (1983) J Immunol Meth , vol.65 , pp. 109-121
    • Czerkinsky, C.C.1    Nilsson, L.2    Nygren, H.3    Ouchterlony, Ö.4    Tarkowski, A.5
  • 17
    • 0020537688 scopus 로고
    • A solid-phase immunoenzymatic technique for the enumeration of specific antibody-secreting cells
    • Sedwick JD, Holt PG. A solid-phase immunoenzymatic technique for the enumeration of specific antibody-secreting cells. J Immunol Meth. 57:1983;301-309.
    • (1983) J Immunol Meth , vol.57 , pp. 301-309
    • Sedwick, J.D.1    Holt, P.G.2
  • 18
    • 0023945701 scopus 로고
    • Reverse ELISPOT assay for clinical analysis of cytokine production. I. Enumeration of gamma-interferon secreting cells
    • Czerkinsky CC, Andersson G, Ekre H-P, Nilsson L-Å, Klareskog L, Ouchterlony Ö. Reverse ELISPOT assay for clinical analysis of cytokine production. I. Enumeration of gamma-interferon secreting cells. J Immunol Meth. 110:1988;29-36.
    • (1988) J Immunol Meth , vol.110 , pp. 29-36
    • Czerkinsky, C.C.1    Andersson, G.2    Ekre, H.-P.3    Nilsson, L.-Å.4    Klareskog, L.5    Ouchterlony, Ö.6
  • 19
    • 0023940215 scopus 로고
    • Enumeration of IFN-gamma producing human lymphocytes by spot-ELISA
    • Versteegen JMT, Logtenberg T, Ballieux RE. Enumeration of IFN-gamma producing human lymphocytes by spot-ELISA. J Immunol Meth. 111:1988;25-29.
    • (1988) J Immunol Meth , vol.111 , pp. 25-29
    • Versteegen, J.M.T.1    Logtenberg, T.2    Ballieux, R.E.3
  • 20
    • 0021856495 scopus 로고
    • Clinical viral infections and multiple sclerosis
    • Sibley WA, Bamford CR, Clark K. Clinical viral infections and multiple sclerosis. Lancet. 8:1985;1313-1315.
    • (1985) Lancet , vol.8 , pp. 1313-1315
    • Sibley, W.A.1    Bamford, C.R.2    Clark, K.3
  • 21
    • 0028333890 scopus 로고
    • Influence of infection on exacerbations of multiple sclerosis
    • Panitch HS. Influence of infection on exacerbations of multiple sclerosis. Ann Neurol. 36:1984;25-28.
    • (1984) Ann Neurol , vol.36 , pp. 25-28
    • Panitch, H.S.1
  • 22
    • 0031776202 scopus 로고    scopus 로고
    • Clinical relapses and disease activity on magnetic resonance imaging associated with viral upper respiratory tract infections in multiple sclerosis
    • Edwards S, Zvartau M, Clarke H, Irving W, Blumhardt LD. Clinical relapses and disease activity on magnetic resonance imaging associated with viral upper respiratory tract infections in multiple sclerosis. J Neurol Neurosurg Psychiatry. 64:1998;736-741.
    • (1998) J Neurol Neurosurg Psychiatry , vol.64 , pp. 736-741
    • Edwards, S.1    Zvartau, M.2    Clarke, H.3    Irving, W.4    Blumhardt, L.D.5
  • 23
    • 0030749896 scopus 로고    scopus 로고
    • Intracellular Salmonella dublin induces substantial secretion of the 40-kilodalton subunit of interleukin-12 (IL-12) but minimal secretion of IL-12 as a 70-kilodalton protein in murine macrophages
    • 3192
    • Bost, KL, Clements, JD, 1997, Intracellular Salmonella dublin induces substantial secretion of the 40-kilodalton subunit of interleukin-12 (IL-12) but minimal secretion of IL-12 as a 70-kilodalton protein in murine macrophages. Infect Immun, 65, 3186, 3192.
    • (1997) Infect Immun , vol.65 , pp. 3186
    • Bost, K.L.1    Clements, J.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.