Molecular mechanisms of apoptosis in HL-60 cells induced by a nitric oxide-releasing compound

Free Radical Research

Volumn 27, Issue 3, 1997, Pages 325-335

  Yabuki, Munehisa ^a   Kariya, Shinji ^b,d   Inai, Yoko ^b,e   Hamazaki, Keisuke ^b   Yoshioka, Tamotsu ^b   Yasuda, Tatsuji ^a   Horton, Alan A ^c   Utsumi, Kozo ^b  

^a OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b University of Tokyo   (Japan)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d KOCHI MEDICAL SCHOOL   (Japan)

^e University of Tokyo   (Japan)

Author keywords

Apoptosis; Bax; Bcl 2; Caspase; Cell differentiation; CPP32; DNA fragmentation; HL 60 cells; ICE; Nitric oxide; Tyrosine phosphorylation

Indexed keywords

DNA FRAGMENT; HERBIMYCIN A; INTERLEUKIN 1BETA CONVERTING ENZYME; NITRIC OXIDE; NONSPECIFIC ESTERASE; PROTEIN BAX; PROTEIN BCL 2; TRIAZENE DERIVATIVE; TYROSINE; VANADIC ACID;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELL STRAIN HL 60; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MONOCYTE; PROTEIN PHOSPHORYLATION;

EID: 0030666180     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.3109/10715769709065770     Document Type: Article

References (46)

1. Moncada, S., Palmer, R. M. J. and Higgs, E. A. (1991). Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacology Reviews, 43, 109-142.
2. Bredt, D. S. and Snyder, S. H. (1992). Nitric oxide, a novel neuronal messenger. Neuron, 8, 3-11.
3. Knowles, R. G. and Moncada, S. (1992). Nitric oxide as a signal in blood vessels. Trends in Biochemical Sciences, 17, 399-402.
4. Garthwaite, J. (1991). Glutamate, nitric oxide and cell-cell signaling in the nervous system. Trends in Neuroscience, 14, 60-67.
5. Sarih, M., Souvannavong, V. and Adam, A. (1993). Nitric oxide synthase induces macrophage death by apoptosis. Biochemical and Biophysical Research Communications, 191, 503-508.
6. Albina, J. E., Cui, S., Mateo, R. B. and Reichner, J. S. (1993). Nitric oxide-mediated apoptosis in murine peritoneal macrophages, Journal of Immunology, 150, 5080-5085.
7. Meßmer, U. K., Ankarcrona, M., Nicotera, P. and Brüne, B. (1994). p53 expression in nitric oxide-induced apoptosis. FEBS Letters, 355, 23-26.
8. Yabuki, M., Inai, Y., Yoshioka, T., Hamazaki, K., Yasuda, T., Inoue, M. and Utsumi, K. (1997). Oxygen-dependent fragmentation of cellular DNA by nitric oxide. Free Radical Research, 26, 245-255.
9. Boss, G. R. (1989). cGMP-induced differentiation of the promyelocytic cell line HL-60. Proceedings of the National Academy of Sciences of the U. S. A., 86, 7174-7178.
10. Magrinat, G., Mason, S. N., Shami, P. J. and Weinberg, J. B. (1992). Nitric oxide modulation of human leukemia cell differentiation and gene expression. Blood, 80, 1880-1884.
11. Kuo, M. L., Chau, Y. P., Wang, J. H. and Shiah, S. G. (1996). Inhibitors of poly(ADP-ribose) polymerase block nitric oxide-induced apoptosis but not differentiation in human leukemia HL-60 cells. Biochemical and Biophysical Research Communications, 219, 502-508.
12. Tsujimoto, Y., Finger, L. R., Yunis, J., Nowell, P. C. and Croce, C. M. (1984). Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science, 226, 1097-1099.
13. Cleary, M. L, Smith, S. D. and Sklar, J. (1986). Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation. Cell, 47, 19-28.
14. Tsujimoto, Y. and Croce, C. M. (1986). Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma. Proceedings of the National Academy of Sciences of the U. S. A., 83, 5214-5218.
15. Vaux, D. L. (1993). Toward an understanding of the molecular mechanisms of physiological cell death. Proceedings of the National Academy of Sciences of the U. S. A., 90, 786-789.
16. Reed, J. C. (1994). Bcl-2 and the regulation of programmed cell death. Journal of Cell Biology, 124, 1-6.
17. Oltvai, Z. N., Milliman, C. L. and Korsmeyer, S. J. (1993). Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell, 74, 609-619.
18. Yin, X. M., Oltvai, Z. N. and Korsmeyer, S. J. (1994). BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature, 369, 321-323.
19. Delia, D., Aiello, A., Soligo, D., Fontanella, E., Melani, C., Pezzella, F., Pierotti, M. A. and Della, P. G. (1992). bcl-2 proto-oncogene expression in normal and neoplastic human myeloid cells. Blood, 79, 1291-1298.
20. Yuan, J., Shaham, S., Ledoux, S., Ellis, H. M. and Horvitz, H. R. (1993). The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell, 75, 641-652.
21. Miura, M., Zhu, H., Rotello, R., Hartwieg, E. A. and Yuan, J. (1993). Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell, 75, 653-660.
22. Alnemri, E. S., Livingston, D. J., Nicholson, D. W., Salvesen, G., Thornberry, N. A., Wong, W. W. and Yuan, J. (1996). Human ICE/CED-3 protease nomenclature. Cell, 87, 171.
23. Fernandes-Alnemri, T., Litwack, G. and Alnemri, E. S. (1994). CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian Interleukin-1β-converting enzyme, Journal of Biological Chemistry, 269, 30761-30764.
24. Tewari, M., Quan, L. T., O'Rourke, K., Desnoyers, S., Zeng, Z., Beidler, D. R., Poirier, G. G., Salvesen, G. S. and Dixit, V. M. (1995). Yama/CPP32b, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell, 81, 801-809.
25. Nicholson, D. W., Ali, A., Thornberry, N. A., Vaillancourt, J. P., Ding, C. K., Gallant, M., Gareau, Y., Griffin, P. R., Labelle, M., Lazebnik, Y. A., Munday, N. A., Raju, S. M., Smulson, M. E., Yamin, T.-T., Yu, V. L. and Miller, D. K. (1995). Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature, 376, 37-43.
26. Hunter, T. and Cooper, J. A. (1985). Protein-tyrosine kinases. Annual Review of Biochemistry, 54, 897-930.
27. Bergamaschi, G., Rosti, V., Danova, M., Ponchio, L., Lucotti, C. and Cazzola, M. (1993). Inhibitors of tyrosine phosphorylation induce apoptosis in human leukemic cell lines. Leukemia, 7, 2012-2018.
28. Johnson, K. L., Vaillant, F. and Lawen, A. (1996). Protein tyrosine kinase inhibitors prevent didemnin B-induced apoptosis in HL-60 cells. FEBS Letters, 383, 1-5.
29. Hrabie, J. A., Klose, J. R., Wink, D. A. and Keefer, L. K. (1993). New nitric oxide-releasing zwitterions derived from polyamines. Journal of Organic Chemistry, 58, 1472-1476.
30. Collins, S. J. (1987). The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression. Blood, 70, 1233-1244.
31. Yam, L. T., Li, C. Y. and Crosby, W. H. (1971). Cytochemical identification of monocytes and granulocytes. American Journal of Clinical Pathology, 55, 283-290.
32. Sellins, K. S. and Cohen, J. J. (1987). Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes, Journal of Immunology, 139, 3199-3206.
33. Burton, K. (1956). A study of the conditions and mecha-nisms of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochemical Journal, 62, 315-323.
34. Sambrook, J., Fritsch, E. F. and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual, 2nd Ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
35. Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Randall, R. J. (1951). Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry, 193, 265-275.
36. Laemmli, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227, 680-685.
37. Thornberry, N. A., Bull, H. G., Calaycay, J. R.,Chapman, K. T., Howard, A. D., Kostura, M. J., Miller, D. K., Molineaux, S. M., Weidner, J. R., Aunins, J., Elliston, K. O., Ayala, J. M., Casano, R. J., Chin, J., Ding, G. J.-F., Egger, L. A., Gaffney, E. P., Limjuco, G., Palyha, O. C., Raju, S. M., Rolando, A. M., Salley, J. P., Yamin, T. T., Lee, T. D., Shively, J. E., MacCoss, M., Mumford, R. A., Schmidt, J. A. and Tocci, M. J. (1992). A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes. Nature, 356, 768-774.
38. Martin, S. J., Bradley, J. G. and Cotter, T. G. (1990). HL-60 cells induced to differentiate towards neutrophils subsequently die via apoptosis. Clinical and Experimental Immunology, 79, 448-453.
39. Meßmer, U. K., Reed, J. C. and Brüne, B. (1996). Bcl-2 protects macrophages from nitric oxide-induced apoptosis. Journal of Biological Chemistry, 271, 20192-20197.
40. Wolf, D. and Rotter, V. (1985). Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells. Proceedings of the National Academy of Sciences of the U.S.A., 82, 790-794.
41. Meßmer, U. K., Reimer, D. M., Reed, J. C. and Brüne, B. (1996). Nitric oxide induced poly(ADP-ribose) polymerase cleavage in RAW 264.7 macrophage apoptosis is blocked by Bcl-2. FEBS Letters, 384, 162-166.
42. Schlegel, J., Peters, I., Orrenius, S., Miller, D. K., Thornberry, N. A., Yamin, T.-T. and Nicholson, D. W. (1996). CPP32/Apopain is a key interleukin 1β converting enzyme-like protease involved in Fasmediated apoptosis. Journal of Biological Chemistry, 271, 1841-1844.
43. Katagiri, K., Katagiri, T., Koyama, Y., Morikawa, M., Yamamoto, T. and Yoshida, T. (1991). Expression of src family genes during monocytic differentiation of HL-60 cells. Journal of Immunology, 146, 701-707.
44. Katagiri, K., Katagiri, T., Kajiyama, K., Uehara, Y., Yamamoto, T. and Yoshida, T. (1992). Modulation of monocytic differentiation of HL-60 cells by inhibitors of protein tyrosine kinases. Cellular Immunology, 140, 282-294.
45. Stamler, J. S., Simon, D. I., Osborne, J. A., Mullins, M. E., Jaraki, O., Michel, T., Singel, D. J. and Loscalzo, J. (1992). S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds. Proceedings of the National Academy of Sciences of the U. S. A., 89, 444-448.
46. Walton, K. M. and Dixon, J. E. (1993). Protein tyrosine phosphatases. Annual Review of Biochemistry, 62, 101-120.