Human immunodeficiency virus type 1 infection modulates the interleukin (IL)-1β and IL-6 responses of human macrophages to CD40 ligand stimulation

Journal of Infectious Diseases

Volumn 182, Issue 3, 2000, Pages 776-784

  Bergamini, Alberto ^a   Bolacchi, Francesca ^a   Bongiovanni, Barbara ^a   Colizzi, Vittorio ^b,c,d   Cappelli, Giulia ^d,e   Uccella, Ilaria ^a   Cepparulo, Mario ^a   Capozzi, Marcella ^a   Mancino, Giorgio ^b,c,d   Rocchi, Giovanni ^a  

^a Department of Public Health and Cellular Biology   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c FATEBENEFRATELLI HOSPITAL   (Italy)

^d NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

^e CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1 (NAPHTHOXYACETYL)HISTIDYL(5 AMINO 6 CYCLOHEXYL 3,4 DIHYDROXY 2 ISOPROPYLHEXANOYL)ISOLEUCINE N (2 PYRIDYLMETHYL)AMIDE; CD40 ANTIGEN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 4; OKT 4; POLYMYXIN B;

ARTICLE; CYTOFLUOROMETRY; CYTOKINE PRODUCTION; DOSE TIME EFFECT RELATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IMMUNE RESPONSE; MACROPHAGE ACTIVATION; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TRANSCRIPTION REGULATION;

ANTI-HIV AGENTS; ANTIBODIES, MONOCLONAL; CD40 LIGAND; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HIV INFECTIONS; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; MACROPHAGES; OLIGOPEPTIDES; POLYMERASE CHAIN REACTION; RNA, MESSENGER; VIRUS REPLICATION; ZIDOVUDINE;

EID: 0033827359     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/315803     Document Type: Article

References (51)

1. Interleukin 1 inhibitor masks high interleukin 1 production in acquired immunodeficiency syndrome (AIDS)
2. Interleukin-1 activity in the acquired immunodeficiency syndrome
3. Human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system: An evaluation of cytokines in cerebrospinal fluid
4. Infection with HIV is associated with elevated IL-6 levels and production
5. Interleukin-1
6. The biology of interleukin 6
7. Interleukin-6 induces human immunodeficiency virus expression in infected monocytic cells alone and in synergy with tumor necrosis factor-α by transcriptional and post-transcriptional mechanisms
8. Parameters affecting the development of non-Hodgkin's lymphoma in patients with severe human immunodeficiency virus infection receiving antiretroviral therapy
9. The human cell antigen gp39, a member of the TNF family, is a ligand for the CD40 receptor: Expression of a soluble form of gp39 with B cell co-stimulatory activity
10. IFN-γ, and 1,25(OH)2D3 induce on THP-1 cells distinct patterns of cell surface antigen expression, cytokine production, and responsiveness to contact with activated T cells
11. CD40-CD40L interactions in T cell activation
12. The CD40 ligand: At the center of the immune universe?
13. Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues
14. CD40 expression by human monocytes: Regulation by and activation of monocytes by the ligand for CD40
15. + T cell contact-dependent activation of monocyte interleukin-1 synthesis
16. Stimulation of CD40 with purified soluble gp 39 induces proinflammatory responses in human monocytes
17. Human T-lymphotropic virus type III infection of human alveolar macrophages
18. Detection of HTLV-III RNA in lungs of patients with AIDS and pulmonary involvement
19. Follicular dendritic cells and virus-like particles in AIDS-related lymphadenopathy
20. Immunohistochemical identification of HTLV-III antigen in brains of patients with AIDS
21. Inhibition of the protease of human immunodeficiency virus blocks replication and infectivity of the virus in chronically infected macrophages
22. Cystamine potently suppresses in vitro HIV replication in acutely and chronically infected human cells
23. Efficient and reproducible new semimicromethod for the detection and titration of HIV in human plasma
24. Beitrag zur kollektiven Behandlung Pharmakologischer Reihenversuche
25. Apoptosis of human monocytes/macrophages in Mycobacterium tuberculosis infection
26. Replication of human immunodeficiency virus in monocytes: Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine
27. A tetrazolium-based colorimetric assay for quantification of HIV-1-induced cytopathogenicity in monocyte-macrophages exposed to macrophage-colony-stimulating factor
28. Enhanced production of tumor necrosis factor-α and interleukin-6, due to prolonged response to lipo-polysaccharide (LPS), in human macrophages infected in vitro with human immunodeficiency virus type 1
29. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
30. OKT3-induced cytokine mRNA expression in human peripheral blood mononuclear cells measured by PCR
31. The inhibitory effect of polymyxin B on endotoxin-induced endogenous pyrogen production
32. Soluble CD14 activates monocytic cells independently of lipopolysaccharide
33. Production of cytokines by peripheral blood monocytes/macrophages infected with human immunodeficiency virus type 1
34. Induction of IL-6 (B cell stimulatory factor-2/IFN-β2) production by HIV
35. Production of tumor necrosis factor-α and interleukin-1βs by monocytic cells infected with human immunodeficiency virus type 1 (HIV-1)
36. Activation of cytokine genes in HIV-1 infected myelomonoblastic cells by phorbol ester and tumor necrosis factor
37. Effects of human immunodeficiency virus and colony stimulating factors on the production of interleukin-6 and tumor necrosis factor-α by monocyte/macrophages type 1 (HIV-1)
38. Interleukin-6 expression in primary macrophages infected with human immunodeficiency virus-1 (HIV-1)
39. HIV-1 induction of CD40 on endothelial cells promotes the outgrowth of AIDS-associated B-cell lymphomas
40. Human immunodeficiency virus type 1 tat protein activates transcription factor NF-κB through the cellular interferon-inducible, double stranded RNA-dependent protein kinase, PKR
41. Induction of activator protein (AP-1) in macrophages by human immunodeficiency virus type-1 NEF is a cell-type-specific response that requires both hck and MAPK signaling events
42. Activation of the Janus kinase 3-STAT5a pathway after CD40 triggering of human monocytes but not resting B cells
43. The HIV-1 gp120 envelope protein has the intrinsic capacity to stimulate monokine secretion
44. Interaction of HIV-1 gp120 molecule fragments with human monocytes: Different requirements for tumor necrosis factor-α and IL-6 production
45. CD40 and CD154 in cell-mediated immunity
46. Regulation of antigen-presenting cell function(s) in lung and airway tissues
47. Localization in situ of the co-stimulatory molecules B7.1, B7.2, CD40 and their ligands in normal human lymphoid tissue
48. In situ expression of B7 and CD40 costimulatory molecules by normal human lung macrophages and epithelioid cells in tuberculoid granulomas
49. Early reduction of the overexpression of CD40L, OX40, and Fas on T cells in HIV-1 infection during triple anti-retroviral therapy: Possible implications for lymphocyte traffic and functional recovery
50. Alveolar macrophages as a cell source of cytokine hyperproduction in HIV-related interstitial lung disease
51. CD40 ligand and IFN-γ synergistically restore IL-12 production in HIV-infected patients