In situ expression of B7 and CD40 costimulatory molecules by normal human lung macrophages and epithelioid cells in tuberculoid granulomas

Clinical and Experimental Immunology

Volumn 116, Issue 2, 1999, Pages 332-339

  Soler, P ^a   Boussaud, V ^a   Moreau, J ^a   Bergeron, A ^a   Bonnette, P ^b   Hance, A J ^a   Tazi, A ^a,c  

^a INSERM   (France)

^b FOCH HOSPITAL   (France)

^c AVICENNE HOSPITAL   (France)

Author keywords

Alveolar macrophages; B7 1; B7 2; CD40; Immune granulomas

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; LIPOPOLYSACCHARIDE;

ACCESSORY CELL; ADULT; AGED; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; CELL ACTIVITY; CLINICAL ARTICLE; CONTROLLED STUDY; EPITHELIOID CELL; FEMALE; GRANULOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS MACROPHAGE; LYMPHOCYTE PROLIFERATION; MACROPHAGE ACTIVATION; MALE; MONOCYTE; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

EID: 0032928147     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1999.00887.x     Document Type: Article

References (28)

1. 1 Holt PG. Regulation of antigen-presenting cell function(s) in lung and airway tissues. Eur Respir J 1993; 6:120-9.
2. 2 Strickland DH, Kees UR, Holt PG. Regulation of T-cell activation in the lung: alveolar macrophages induce reversible T-cell anergy in vitro associated with inhibition of interleukin-2 receptor signal transduction. Immunol 1996; 87:250-8.
3. 3 Upham JW, Strickland DH, Rohinson BWS, Holt PG. Selective inhibition of T cell proliferation but not expression of effector function by human alveolar macrophages. Thorax 1997; 52:786-95.
4. 4 Kraal G, Thepen T, Van Iwaarden JF, Persoons JHA. The role of alveolar macrophages in pulmonary immune function. In: Lipscomb MF, Russel SW, eds. Lung macrophages and dendritic cells in health and disease. New York: Marcel Dekker, 1997; 102:203-20.
5. 5 Robinson DS, Richeldi L, Saltini C, Crystal RG. Granulomatous processes. In: Crystal RG, West JB, eds. The lung, 2nd edn. New York: Scientific Foundations, Raven Press, 1997:2395-409.
6. 6 Zissel G, Ernst M, Schlaak M, Muller-Quernheim J. Accessory function of alveolar macrophages from patients with sarcoidosis and other granulomatous and non granulomatous lung diseases. J Invest Med 1997; 45:75-86.
7. 7 Schlesinger LS. The role of mononuclear phagocytes in tuberculosis. In: Lipscomb MF, Russel SW, eds. Lung macrophages and dendritic cells in health and disease. New York: Marcel Dekker, 1997; 102:437-80.
8. 8 Takada IY, Yamamoto M, Morishita M, Yoshikawa K. Antigen-presenting capacity of alveolar macrophages and monocytes in pulmonary tuberculosis. Eur Respir J 1991; 4:88-93.
9. 9 Kaufman SHE. Immunity to intracellular bacteria. Annu Rev Immunol 1993; 11:129-63.
10. 10 Moller DR, Forman JD, Liu MC et al. Enhanced expression of IL-12 associated with Th1 cytokine profiles in active pulmonary sarcoidosis. J Immunol 1996; 156:4952-60.
11. 11 Bergeron A, Bonay M, Kambouchner M, Lecossier D, Riquet M, Soler P, Hance AJ, Tazi A. Cytokine patterns in tuberculous and sarcoid granulomas: correlations with histopathologic features of the granulomatous response. J Immunol 1997; 159:3034-43.
12. 12 Lenschow DJ, Walunas TL, Bluestone JA. CD28/B7 system of T cell costimulation. Annu Rev Immunol 1996; 14:233-58.
13. 13 Stout RD, Suttles J. The many roles of CD40 in cell-mediated inflammatory responses. Immunol Today 1996; 17:487-92.
14. 14 Chelen CJ, Fang Y, Freeman GJ et al. Human alveolar macrophages present antigen ineffectively due to defective expression of B7 costimulatory cell surface molecules. J Clin Invest 1995; 95:1415-21.
15. 15 Nicod LP, Isler P. Alveolar macrophages in sarcoidosis coexpress high levels of CD86 (B7.2), CD40, and CD30L. Am J Respir Cell Mol Biol 1997; 17:91-96.
16. 16 Kobzik L. Methods to isolate and study lung macrophages. In: Lipscomb MF, Russel SW, eds. Lung macrophages and dendritic cells in health and disease. New York: Marcel Dekker, 1997; 102:111-29.
17. 17 Tazi A, Fajac I, Soler P, Valeyre D, Ballesti JP, Hance AJ. Gamma/ Delta T-lymphocytes are not increased in number in granulomatous lesions of patients with tuberculosis or sarcoidosis. Am Rev Respir Dis 1991; 144:1373-5.
18. 18 Fajac I, Tazi A, Hance AJ, Bouchonnet F, Riquet M, Battesti JP, Soler P. Lymphocytes infiltrating normal human lung and lung carcinomas rarely express γ/δ T cell antigen receptors. Clin Exp Immunol 1992; 87:127-31.
19. 19 Hathcock KS, Laszlo G, Pucillo C, Linsley P, Hodes RJ. Comparative expression of B7-1 and B7-2 costimulatory ligands: expression and function. J Exp Med 1994; 180:631-40.
20. 20 Inaba K, Witmer-Pack M, Inaba M et al. The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro. J Exp Med 1994; 180:1849-60.
21. 21 Thomas R, Davis LS, Lipsky PE. Comparative accessory cell function of human peripheral blood dendritic cells and monocytes. J Immunol 1993; 151:6840-52.
22. 22 Creery WD, Diaz-Mitoma F, Filion L, Kumar A. Differential modulation of B7-1 and B7-2 isoform expression on human monocytes by cytokines which influence the development of T helper cell phenotype. Eur J Immunol 1996; 26:1273-7.
23. 23 Vyth-Dreese FA, Dellemijn TAM, Majoor D, de Jong D. Localization in situ of the co-stimulatory molecules B7.1, B7.2, CD40 and their ligands in normal lymphoid tissue. Eur J Immunol 1995; 25:3023-9.
24. 24 Wilkes DS, Weissler JC. Alloantigen-induced immunoglobulin production in human lung: differential effects of accessory cell populations on IgE synthesis. Am J Respir Cell Mol Biol 1994; 10:339-46.
25. 25 Costabel U, Guzman J. Effect of smoking on bronchoalveolar lavage constituents. Eur Respir J 1992; 5:776-9.
26. 26 Munro JM, Freedman AS, Aster JC, Gribben JG, Lee NC, Rhynhart KK, Banchereau J, Nadler LM. In vivo expression of the B7 costimulatory molecule by subsets of antigen-presenting cells and the malignant cells of Hodgkin's disease. Blood 1994; 83:793-8.
27. 27 Rathore A, Sacristan C, Ricklan DE, Flores Villanueva PO, Stadecker MJ. In situ analysis of B7-2 costimulatory, major histocompatibility complex class II, and adhesion molecule expression in schistosomal egg granulomas. Am J Pathol 1996; 149:187-94.
28. 28 Subramanian G, Kazura JW, Pearlman E, Jia XL, Malhotra I, King CL. B7-2 requirement for helminth-induced granuloma formation and CD4 type 2 T helper cell cytokine expression. J Immunol 1997; 158:5914-20.