Genetic and teratogenic approaches to craniofacial development

Critical Reviews in Oral Biology and Medicine

Volumn 11, Issue 3, 2000, Pages 304-317

  Young, D L ^a   Schneider, R A ^a   Hu, D ^a   Helms, J A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Birth defects; Cleft lip palate; Dlx; EGFR; Facial primordia; Gene knockouts; Retinoic acid; Shh; TGF 3

Indexed keywords

CYCLOPAMINE; EPIDERMAL GROWTH FACTOR; JERVINE; RETINOIC ACID; SONIC HEDGEHOG PROTEIN; TERATOGENIC AGENT; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DISTAL LESS; TRANSFORMING GROWTH FACTOR BETA3; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; CLEFT FACE; CRANIOFACIAL DEVELOPMENT; CRANIOFACIAL MALFORMATION; CRANIOFACIAL MORPHOLOGY; EXTRACELLULAR MATRIX; GENE DISRUPTION; HUMAN; MORPHOGENESIS; MOUSE; NONHUMAN; PALATE; PRIORITY JOURNAL; VERATRUM;

EID: 0033820535     PISSN: 10454411     EISSN: None     Source Type: Journal    
DOI: 10.1177/10454411000110030201     Document Type: Article

References (121)

1. Transcription factors and head formation in vertebrates
2. Multiple roles of cholesterol in hedgehog protein biogenesis and signaling
3. Origins and developmental potential of the neural crest
4. Alterations in Msx 1 and Msx 2 expression correlate with inhibition of outgrowth of chick facial primordia induced by retinoic acid
5. The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
6. Inhibition of TGF-beta 3 (but not TGF-beta 1 or TGF beta 2) activity prevents normal mouse embryonic palate fusion
7. Proceedings: Effects of alkaloids of Veratrum californicum on developing embryos
8. The mouse Dlx-2 (Tes-1) gene is expressed in spatially restricted domains of the forebrain, face and limbs in midgestation mouse embryos
9. The fate of medial edge epithelial cells during palatal fusion in vitro: An analysis by Dil labelling and confocal microscopy
10. Niemann-Pick C1 disease gene: Homology to mediators of cholesterol homeostasis
11. Sprouty, an intracellular inhibitor of Ras signaling
12. Cleft lip with or without cleft palate: Associations with transforming growth factor alpha and retinoic acid receptor loci
13. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
14. Teratogen-mediated inhibition of target tissue response to Shh signaling
15. The triple origin of skull in higher vertebrates: A study in quail-chick chimeras
16. Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis
17. Expression of the gene during facial, ocular murine Dlx-1 homeobox and limb development
18. Proteinase requirements of epidermal growth factor-induced ovarian cancer cell invasion
19. Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity
20. Palate development
21. Experimental fusion of the naturally cleft, embryonic chick palate
22. Medial edge epithelium transforms to mesenchyme after embryonic palatal shelves fuse
23. Differential expression of TGF beta isoforms in murine palatogenesis
24. Disruption of Msx-1 and Msx-2 reveals roles for these genes in craniofacial, eye, and axial development
25. Expression of the mouse goosecoid gene during mid-embryogenesis may mark mesenchymal cell lineages in the developing head, limbs and body wall
26. Cell death in normal vetebrate ontogeny
27. Neural crest apoptosis and the establishment of craniofacial pattern: An honorable death
28. Retinoic acid exposure of the mouse on embryonic day 9 selectively spares derivatives of the frontonasal neural crest
29. Inhibition of epithelial cell death in the secondary palate in vitro by alteration of lysosome function
30. Epithelial-mesenchymal transformation during palatal fusion: Carboxyfluorescein traces cells at light and electron microscopic levels
31. A series of normal stages in the development of the chick embryo
32. Cleft lip and palate: No evidence of linkage to transforming growth factor alpha
33. Retinoic acid signaling is required during early chick limb development
34. Sonic hedgehog participates in craniofacial morphogenesis and is down-regulated by teratogenic doses of retinoic acid
35. Regional pattern of retinoid X receptor-alpha gene expression in the central nervous system of the chicken embryo and its up-regulation by exposure to 9-cis retinoic acid
36. The role of Sonic hedgehog in normal and abnormal craniofacial morphogenesis
37. Deciphering the Hox code: Clues to patterning branchial regions of the head
38. Restoration of normal Hox code and branchial arch morphogenesis after extensive deletion of hindbrain neural crest
39. Introduction: Retinoic acid and its receptors in development
40. Barx2, a new homeobox gene of the Bar class, is expressed in neural and craniofacial structures during development
41. Abnormal lung development and cleft palate in mice lacking TGF-β3 indicates defects of epithelial-mesenchymal interaction
42. Transforming growth factor-beta3 regulates transdifferentiation of medial edge epithelium during palatal fusion and associated degradation of the basement membrane
43. Teratogenic compounds of Veratrum californicum (Durand). V. Comparison of cyclopian effects of steroidal alkaloids from the plant and structurally related compounds from other sources
44. Holoprosencephaly in RSH/Smith-Lemli-Opitz syndrome: Does abnormal cholesterol metabolism affect the function of Sonic Hedgehog?
45. The TGF-beta superfamily: New members, new receptors, and new genetic tests of function in different organisms
46. Rhombencephalic neural crest segmentation is preserved throughout craniofacial ontogeny
47. Hox homeobox genes and regionalisation of the nervous system
48. Developmental patterning and evolution of the mammalian viscerocranium: Genetic insights into comparative morphology
49. Murine model of Niemann-Pick C disease: Mutation in a cholesterol homeostasis gene
50. Function of the retinoic acid receptors (RARs) during development (l). Craniofacial and skeletal abnormalities in RAR double mutants
51. Dysgenesis of cephalic neural crest derivatives in Pax7-/- mutant mice
52. Mouse Qtx2 functions in the formation and patterning of rostral head
53. Fate map of the developing chick face: Analysis of expansion of facial primordia and establishment of the primary palate
54. Epidermal growth factor receptor function is necessary for normal craniofacial development and palate closure
55. Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis
56. Retinoic acid and craniofacial development: Molecules and morphogenesis
57. FGF signaling in skeletal development
58. The control of avian cephalic neural crest cytodifferentiation: 1. Skeletal and connective tissues
59. The role of the neural crest in patterning of avian cranial skeletal, connective, and muscle tissues
60. Origins and patterning of craniofacial mesenchymal tissues
61. Expression of retinoic acid receptor genes in neural crest-derived cells during mouse facial development
62. The contribution of both forebrain and midbrain crest cells to the mesenchyme in the frontonasal mass of mouse embryos
63. Differential expression of genes encoding TGFs beta 1, beta 2, and beta 3 during murine palate formation
64. Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: Expression patterns suggest multiple roles during embryonic development
65. Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities
66. Members of the Dlx- and Nkx2-gene families are regionally expressed in the developing forebrain
67. Transforming growth factor-beta 3 is required for secondary palate fusion
68. Null mutation of Dlx-2 results in abnormal morphogenesis of proximal first and second branchial arch derivatives and abnormal differentiation in the forebrain
69. Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: Mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tis-I sue structures derived from the first and second arches
70. The role of retinoids in normal and abnormal embryonic craniofacial morphogenesis
71. Epithelia are interchangeable between facial primordia of chick embryos and morphogenesis is controlled by the mesenchyme
72. Goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development
73. Differentia and overlapping expression domains of Dlx-2 and Dlx-3 suggest distinct roles for Distal-less homeobox genes in craniofacial development
74. Mutations in the h man Sonic Hedgehog gene cause holoprosencephaly
75. Expression of the chicken retinoid X receptor-gamma gene in migrating cranial neural crest cells
76. A member of the RXR nuclear receptor family is expressed in neural-crest-derived cells of the developing chick peripheral nervous system
77. Retinoic acid treatment alters the distribution of retinoic acid receptor-beta transcripts in the embryonic chick face
78. Development of the spatial pattern of retinoic acid receptor-beta transcripts in embryonic chick facial primordia
79. Patterning of the embryonic forebrain
80. Retinoic acid receptors and cellular retinoid binding proteins. II. Their differential pattern of transcription during early morphogenesis in mouse embryos
81. Retinoic acid receptors and cellular retinoid binding proteins. III. Their differential transcript distribution during mouse nervous system development
82. Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development
83. Death in embryonic systems
84. Genetic analysis of craniofacial development in the vertebrate embryo
85. Differential expression of TGF beta 1, beta 2 and beta 3 genes during mouse embryogenesis
86. Neural crest can form cartilages normally derived from mesoderm during development of the avian head skeleton
87. Development and regeneration of the musculoskeletal system
88. From head to toe: Conservation of molecular signals regulating limb and craniofacial morphogenesis
89. Transcription factor AP-2 essential for cranial closure and craniofacial development
90. Vital dye analysis of cranial neural crest cell migration in the mouse embryo
91. Development of the secondary palate in chick embryo: A light and electron microscopic and histochemical study
92. Secondary palate development in the domestic duck (Khaki Campbell). An electron microscopic, histochemical, autoradiographic and biochemical study
93. Electron microscopic and histochemical examination of oral epithelial-mesenchymal interaction (programmed cell death)
94. Chicken transcription factor AP-2: Cloning, expression and its role in outgrowth of facial prominences and limb buds
95. Association of transforming growth-factor alpha gene polymorphisms with nonsyndromic cleft palate only (CPO)
96. Medial edge epithelium fate traced by cell lineage analysis during epithelial-mesenchymal transformation in vivo
97. Nested expression domains of four homeobox genes in developing rostral brain
98. Have gene knockouts caused evolutionary reversals in the mammalian first arch?
99. Retinoic acid receptor isoform beta 2 is an early marker for alimentary tract and central nervous system positional specification in the chicken
100. Temporal and regional differences in the expression pattern of distinct retinoic acid receptor-beta transcripts in the chick embryo
101. Retinoic acid and retinoic acid receptors in development
102. TGFbeta3 promotes transformation of chicken palate medial edge epithelium to mesenchyme in vitro
103. Matrix metalloproteinase-3 releases active heparin-binding EGF-like growth factor by cleavage at a specific juxtamembrane site
104. Analysis of upper beak defects in chicken embryos following with retinoic acid
105. Pathogenesis of cleft palate in TGFb3 knockout mice
106. Prx1 and Prx2 in skeletogenesis: Roles in the craniofacial region, inner ear and limbs
107. Inhibition of retinoic acid receptor-mediated signalling alters positional identity in the developing hindbrain
108. No evidence of linkage between the transforming growth factor-alpha gene in families with apparently autosomal dominant inheritance of cleft lip and palate
109. Epithelial-mesenchymal interactions in the development of chick facial primordia and the target of retinoid action
110. Effects of retinoids on chick face development
111. Defective forebrain development in mice lacking gp330/megalin
112. No evidence of linkage for cleft lip with or without cleft palate to a marker near the transforming growth factor alpha locus in two populations
113. Targeted mutation of the murine goosecoid gene results in craniofacial defects and death
114. Changes of the expression and distribution of retinoic acid receptors during neurogenesis in mouse embryos
115. Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2