Different mechanisms for dopaminergic excitation induced by opiates and cannabinoids in the rat midbrain

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 24, Issue 6, 2000, Pages 993-1006

  Melis, Miriam ^a   Gessa, Gian Luigi ^a   Diana, Marco ^a,b  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b UNIVERSITY OF SASSARI   (Italy)

Author keywords

Cannabinoids; Dopamine; Electrophysiology; Nucleus accumbens; Opiates; Substantia nigra

Indexed keywords

CANNABINOID; OPIATE; RIMONABANT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDROMIC STIMULATION; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC TRANSMISSION; HYPERPOLARIZATION; MESENCEPHALON; NERVE EXCITABILITY; NONHUMAN; NUCLEUS ACCUMBENS; RAT; SINGLE UNIT ACTIVITY; SUBSTANTIA NIGRA; WITHDRAWAL SYNDROME;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HALLUCINOGENS; INJECTIONS, INTRAVENOUS; MALE; MORPHINE; NARCOTICS; NUCLEUS ACCUMBENS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE; SUBSTANTIA NIGRA; TETRAHYDROCANNABINOL; VISUAL CORTEX;

EID: 0033816276     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-5846(00)00119-6     Document Type: Article

References (35)

1. Effects of some cannabinoids on naloxone-precipitated abstinence in morphine dependent mice
2. The effects of thyrotropin releasing hormone and histidyl-proline diketopiperazine on delta-9-tetrahydrocannabinol-induced hypothermia
3. Influence of thyrotropin releasing hormone and histidyl-proline diketopiperazine on spontaneous locomotor activity and analgesia induced by delta 9-tetrahydrocannabinol in the mouse
4. 9-Tetrahydrocannabinol in the mouse
5. 9-Tetrahydrocannabinol produces enhancement of presynaptic basal dopamine efflux in necleus accumbens of conscious, freely-moving rats as measured by intracerebral microdialysis
6. 9-Tetrahydrocannabinol enhances presynaptic dopamine efflux in medial prefrontal cortex
7. Electrophysiological properties of identified output neurons of the rat substantia nigra (pars compacta and pars reticulata): Evidence for the existence of branched neurons
8. Cannabinoid pharmacology
9. Electrophysiological analysis of dopamine cells from the substantia nigra pars compacta of circling rats
10. Morphine suppression of substantia nigra zona reticulata neurons in the rat: Implicated role for a novel striatonigral feedback mechanism
11. Cannabinoids excite dopamine neurons in the ventral tegmentum and substantia nigra
12. 9-Tetrahydrocannabinol excites rat VTA dopamine neurons through activation of cannabinoid CB1 but not opioid receptors
13. Marijuana's interaction with brain reward systems: Update 1991
14. Cannabinoid transmission and reward-related events
15. 9-Tetrahydrocannabinol is mediated by an endogenous opioid mechanism
16. Cannabinoids activate mesolimbic dopamine neurons by an action on cannabinoid CB1 receptors
17. 9-Tetrahydrocannabinol on the activity of A10 dopamine neurons recorded in vivo on anesthetized rats
18. Intracellular and extracellular electrophysiological of nigral dopaminergic neurons-1. Identification and characterization
19. Morphine-induced activation of A10 dopamine neurons in the rat
20. Cannabinoid receptor localization in the brain
21. Neuronal localization of cannabinoid receptors in the basal ganglia of the rat
22. Morphine-dependent rats: Blockade of precipitated abstinence by tetrahydrocannabinol
23. Opioids excite dopamine neurons by hyperpolarization of local interneurons
24. 9-tetrahydrocannabinol-tolerant rats
25. Anesthetic influences on the basal activity and pharmacological responsiveness of nigrostriatal dopamine neurons
26. Antidromic activation of neurones as an analytic tool in the study of central nervous system
27. Modulation of GABAergic transmission in the globus pallidus by the synthetic cannabinoid WIN 55, 212-2
28. Anatomy of CNS opioid receptors
29. Electrophysiological evidence for excitation of rat ventral tegmental area dopamine neurons by morphine
30. Effects of a cannabinoid on spontaneous and evoked neuronal activity in the substantia nigra pars reticulata
31. CB1 cannabinoid eceptor antagonist-induced opiate withdrawal in morphine-dependent rats
32. Dopaminergic neurons: Effect of acute and chronic morphine administration on single cell activity and trasmitter metabolism
33. Role of the subthalamic nucleus in cannabinoid actions in the substantia nigra of the rat
34. 1 opioid receptor mechanism
35. Local pressure application of cannabinoid agonists increases spontaneous activity of rat substantia nigra pars reticulata neurons without affecting response to iontophoretically-applied GABA