Rapid relief of block by mecamylamine of neuronal nicotinic acetylcholine receptors of rat chromaffin cells in vitro: An electrophysiological and modeling study

Molecular Pharmacology

Volumn 58, Issue 4, 2000, Pages 778-787

  Giniatullin, Rashid A ^a,b   Sokolova, Elena M ^a   Di Angelantonio, Silvia ^a   Skorinkin, Andrei ^a,c   Talantova, Maria V ^a,b   Nistri, Andrea ^a  

^a SISSA   (Italy)

^b KAZAN STATE MEDICAL UNIVERSITY   (Russian Federation)

^c KAZAN FEDERAL UNIVERSITY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINERGIC RECEPTOR; DIHYDRO BETA ERYTHROIDINE; MECAMYLAMINE; NICOTINE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; PROADIFEN; STILBENE DERIVATIVE; TUBOCURARINE CHLORIDE;

ANIMAL CELL; ARTICLE; CHOLINERGIC SYSTEM; CHROMAFFIN CELL; COMPUTER MODEL; CONTROLLED STUDY; MEMBRANE CURRENT; MEMBRANE ELECTROPHYSIOLOGY; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING;

EID: 0033807423     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.58.4.778     Document Type: Article

References (40)

1. End-plate channel opening and the kinetics of quinacrine (mepacrine) block
2. Interaction of tetraethylammonium ion derivatives with the potassium channels of giant axons
3. Studies on the mechanism of action of acetylcholine antagonists on rat parasympathetic ganglion cells
4. Continuous approximation with embedded Runge-Kutta methods
5. Synaptic transmission at visualized sympathetic boutons: Stochastic interaction between acetylcholine and its receptors
6. Trapping channel block of NMDA-activated responses by amantadine and memantine
7. Multiple actions of substance P that regulate the functional properties of acetylcholine receptors of clonal rat PC12 cells
8. Open-channel blockers at the human α4β2 neuronal nicotinic acetylcholine receptor
9. Neuronal nicotinic acetylcholine receptors on bovine chromaffin cells: Cloning, expression and genomic organization of receptor subunits
10. Mechanism of memantine block of NMDA-activated channels in rat retinal ganglion cells: Uncompetitive antagonism
11. An algorithmic method for determining the kinetic system of receptor-channel complex
12. Substance P reduces acetylcholine-induced currents in isolated bovine chromaffin cells
13. Binding, gating, affinity and efficacy: The interpretation of structure-activity relationships for agonists and of the effects of mutating receptors
14. Relaxation and fluctuations of membrane currents that flow through drug-operated channels
15. Alpha 4-2 beta 2 and other nicotinic acetylcholine receptor subtypes as target of psychoactive and addictive drugs
16. Open channel block alteration of N-methyl-D-aspartic acid receptor gating by an analog of phencyclidine
17. The glutamate receptor ion channels
18. Acetylcholine-evoked currents in cultured neurones dissociated from rat parasympathetic cardiac ganglia
19. 2+ in rat chromaffin cells in vitro
20. Development of desensitization during repetitive end-plate activity and single end-plate currents in frog muscle
21. 5-Hydroxytriptamine blocks the fetal more potently than the adult mouse muscle acetylcholine receptor
22. The channel-blocking action of methonium compounds on rat submandibular ganglion cells
23. Methods for the examination of ganglion-blocking activity
24. Voltage dependent block by magnesium of neuronal nicotinic acetylcholine receptor channels in rat phaechromocytoma cells
25. Different types of blockade of crustacean acetylcholine-induced currents
26. Both α- and β-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors
27. A study of bovine adrenal chromaffin nicotinic receptor using patch clamp and concentration-jump techniques
28. Rectification of currents activated by nicotinic acetylcholine receptors in rat sympathetic ganglion neurones
29. Conductance and kinetic properties of single nicotinic acetylcholine receptor channels in rat sympathetic neurones
30. The charge carried by single-channel currents of rat cultured muscle cells in the presence of local anaesthetics
31. Single channel properties of human α3 AChRs: Impact of β2, β4 and α5 subunits
32. A patch clamp study of the nicotinic acetylcholine receptor of bovine adrenomedullary chromaffin cells in culture
33. State-dependent accessibility and electrostatic potential in the channel of the acetylcholine receptor
34. Receptors for purines and pyrimidines
35. Mecamylamine selectively blocks nicotinic receptors on vasomotor sympathetic C neurons
36. Recombinant nicotinic receptors, expressed in Xenopus oocytes, do not resemble native rat sympathetic ganglion receptors in single-channel behaviour
37. Ionic blockage of sodium channels in nerve
38. Rat α3/β4 subtype of neuronal nicotinic acetylcholine receptor stably expressed in a transfected cell line: Pharmacology of ligand binding and function
39. 4 neuronal nicotinic acetylcholine receptor