Efficient homologous RNA recombination and requirement for an open reading frame during replication of equine arteritis virus defective interfering RNAs

Journal of Virology

Volumn 74, Issue 19, 2000, Pages 9062-9070

  Molenkamp, R ^a   Greve, S ^a   Spaan, W J M ^a   Snijder, E J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT RNA; RNA DIRECTED RNA POLYMERASE;

ANIMAL CELL; ARTICLE; CORONAVIRUS; EQUINE VIRAL ARTERITIS VIRUS; GENE MUTATION; GENETIC RECOMBINATION; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; TOROVIRUS; VIRUS GENOME; VIRUS REPLICATION;

ANIMAL; ARTERITIS VIRUS, EQUINE; GENE EXPRESSION REGULATION, VIRAL; OPEN READING FRAMES; RECOMBINATION, GENETIC; RNA, VIRAL; SUPPORT, NON-U.S. GOV'T; VIRUS REPLICATION;

EID: 0033803593     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.19.9062-9070.2000     Document Type: Article

References (69)

1. Establishing a genetic recombination map for murine coronavirus strain A59 complementation groups
2. Murine coronavirus temperature sensitive mutants
3. Characterization of replicative intermediate RNA of mouse hepatitis virus: Presence of leader RNA sequences on nascent chains
4. Recombination and coronavirus defective interfering RNAs
5. Generation and analysis of non-homologous RNA-RNA recombinants in brome mosaic virus: Sequence complementarities at crossover sites
6. Genetic recombination between RNA components of a multipartite plant virus
7. Nidovirales: A new order comprising Coronaviridae and Arteriviridae
8. cis Requirement for N-specific protein sequence in bovine coronavirus defective interfering RNA replication
9. A cis-acting function for the coronavirus leader in defective interfering RNA replication
10. The fitness of defective interfering murine coronavirus DI-a and its derivatives is decreased by nonsense and frameshift mutations
11. Equine arteritis virus subgenomic mRNA synthesis: Analysis of leader-body junctions and replicative-form RNAs
12. Equine arteritis virus is not a togavirus but belongs to the coronaviruslike superfamily
13. All subgenomic mRNAs of equine arteritis virus contain a common leader sequence
14. Structural proteins of equine arteritis virus
15. The genome organization of the Nidovirales: Similarities and differences between arteri-, toro-, and coronaviruses
16. Isolation of a filterable agent causing arteritis of horses and abortion by mares. Its differentiation from the equine abortion (influenza) virus
17. Identification and characterization of a coronavirus packaging signal
18. Evidence for variable rates of recombination in the MHV genome
19. Map locations of mouse hepatitis virus temperature-sensitive mutants: Confirmation of variable rates of recombination
20. Replication and packaging of transmissible gastroenteritis coronavirus-derived synthetic minigenomes
21. Poliovirus RNA recombination: Mechanistic studies in the absence of selection
22. Multiple recombination sites at the 5'-end of murine coronavirus RNA
23. Analysis of cis-acting sequences essential for coronavirus defective interfering RNA replication
24. The mechanism of RNA recombination in poliovirus
25. Repair and mutagenesis of the genome of a deletion mutant of the coronavirus mouse hepatitis virus by targeted RNA recombination
26. Differential premature termination of transcription as a proposed mechanism for the regulation of coronavirus gene expression
27. Bovine viral diarrhea virus: Characterization of a cytopathogenic defective interfering particle with two internal deletions
28. RNA recombination in animal and plant viruses
29. Recombination in large RNA viruses: Coronaviruses
30. Characterization of leader RNA sequences on the virion and mRNAs of mouse hepatitis virus, a cytoplasmic RNA virus
31. Recombination between nonsegmented RNA genomes of murine coronaviruses
32. The molecular biology of coronaviruses
33. Deletion mapping of Sindbis virus DI RNAs derived from cDNAs defines the sequences essential for replication and packaging
34. High-frequency homologous genetic recombination of an arterivirus, lactate dehydrogenase-elevating virus, in mice and evolution of neuropathogenic variants
35. A cis-acting viral protein is not required for the replication of a coronavirus defective-interfering RNA
36. Deletion mapping of a mouse hepatitis virus defective interfering RNA reveals the requirement of an internal and discontiguous sequence for replication
37. High-frequency RNA recombination of murine coronaviruses
38. Primary structure and translation of a defective interfering RNA of murine coronavirus
39. Reverse genetics of the largest RNA viruses
40. Hybridization of nucleic acids immobilized on solid supports
41. Molecular characterization of transmissible gastroenteritis coronavirus defective interfering genomes: Packaging and heterogeneity
42. Classical swine fever virus: Recovery of infectious viruses from cDNA constructs and generation of recombinant cytopathogenic defective interfering particles
43. Isolation and characterization of an arterivirus defective interfering RNA genome]
44. Genetic recombination in brome mosaic virus: Effect of sequence and replication of RNA on accumulation of recombinants
45. Targeting the site of RNA-RNA recombination in brome mosaic virus with antisense sequences
46. Open reading frame 1a-encoded subunits of the arterivirus replicase induce endoplasmic reticulum-derived double-membrane vesicles which carry the viral replication complex
47. Characterization of a replicating and packaged defective RNA of avian coronavirus infectious bronchitis virus
48. Replication and packaging of coronavirus infectious bronchitus virus defective RNAs lacking a long open reading frame. J. Virol
49. Effect of 5' and 3' terminal sequences, overall length, and coding capacity on the accumulation of defective RNAs associated with broad bean mottle bromovirus in planta
50. Coronaviruses use discontinuous extension for synthesis of subgenome-length negative strands
51. The molecular biology of arteriviruses
52. Identification of a novel structural protein of arteriviruses
53. Proteolytic processing of the replicase ORF1a protein of equine arteritis virus
54. The arterivirus nsp4 protease is the prototype of a novel group of chymotrypsin-like enzymes, the 3C-like serine proteases
55. Coronavirus mRNA synthesis involves fusion of non-contiguous sequences
56. ORF1a-encoded replicase subunits are involved in the membrane association of the arterivirus replication complex
57. A domain at the 3' end of the pol gene is essential for encapsidation of coronaviral defective interfering RNAs
58. Homologous RNA recombination allows efficient introduction of site-specific mutations into the genome of coronavirus MHV-A59 via synthetic co-replicating RNAs
59. Translation but not the encoded sequence is essential for the efficient propagation of the defective interfering RNAs of the coronavirus mouse hepatitis virus
60. An infectious arterivirus cDNA clone: Identification of a replicase point mutation which abolishes discontinuous mRNA transcription
61. Proteolytic processing of the ORF1b-encoded part of the arterivirus replicase is mediated by the nsp4 serine protease and is essential for virus replication
62. Processing of the equine arteritis virus replicase ORF1b protein: Identification of cleavage products containing the putative viral polymerase and helicase domains
63. Arterivirus discontinuous mRNA transcription is guided by base-pairing between sense and antisense transcription-regulating sequences
64. Regulation of coronavirus mRNA transcription
65. Alternative proteolytic processing of the arterivirus ORF1a polyprotein: Evidence that nsp2 acts as a cofactor for the nsp4 serine protease
66. Deletion analysis of a defective interfering Semliki Forest virus RNA genome defines a region in the nsp2 sequence that is required for efficient packaging of the genome into virus particles
67. A defective RNA associated with bamboo mosaic virus and the possible common mechanisms for RNA recombination in potexviruses
68. Recombination between North American strains of porcine reproductive and respiratory syndrome virus