The arterrvirus Nsp4 protease is the prototype of a novel group of chymotrypsin-like enzymes, the 3C-like serine proteases

Journal of Biological Chemistry

Volumn 271, Issue 9, 1996, Pages 4864-4871

  Snijder, Eric J ^a,c   Wassenaar, Alfred L M ^a   Van Dinten, Leonie C ^a   Spaan, Willy J M ^a   Gorbalenya, Alexander E ^b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b CHUMAKOV INSTITUTE OF POLIOMYELITIS AND VIRAL ENCEPHALITIDES   (Russian Federation)

^c Dept of Virology ^*  (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARTERIVIRUS; EQUIDAE; EQUINE ARTERITIS VIRUS;

CHYMOTRYPSIN; PROTEINASE; SERINE PROTEINASE;

AMINO ACID SEQUENCE; ARTERIVIRUS; ARTICLE; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME SUBSTRATE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SEQUENCE HOMOLOGY; VIRUS GENOME; VIRUS REPLICATION;

AMINO ACID SEQUENCE; ANIMALS; ARTERITIS VIRUS, EQUINE; ARTERIVIRUS; BASE SEQUENCE; BINDING SITES; CATTLE; CHYMOTRYPSIN; DNA-DIRECTED DNA POLYMERASE; GENOME, VIRAL; HORSES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OPEN READING FRAMES; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SERINE ENDOPEPTIDASES; SWINE;

EID: 0029966508     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.9.4864     Document Type: Article

References (63)

1. Krausslich, H. G , and Wimmer, E. (1988) Annu. Rev. Biochem. 57, 701-754
2. Strauss, J. H. (ed) (1990) Seminars in Virology, Vol. 1, pp. 307-384, W. B. Saunders, Philadelphia
3. Dougherty, W. G., and Semler, B. L. (1993) Microbiol. Rev. 57, 781-822
4. Gorbalenya, A. E., and Koonin, E. V. (1993) Sov. Sci. Rev. D. Physicochem. Biol. 11, 1-84
5. Gorbalenya, A. E., Donchenko, A. P., Blinov, V. M., and Koonin, E. V. (1989) FEBS Lett. 243, 103-114
6. Bazan, J. F., and Fletterick, R. J. (1989) Virology 171, 637-639
7. Chambers, T J., Hahn, C. S., Galler, R , and Rice, C. M (1990) Annu. Rev. Microbiol. 44, 649-688
8. Choi, H.-K., Tong, L., Minor, W , Dumas, P., Boege, U., Rossmann, M. G., and Wengler, G. (1991) Nature 354, 37-43
9. Bazan, J. F., and Fletterick. R. J (1988) Proc Natl. Acad. Sci. U. S. A. 85, 7872-7876
10. Allaire, M., Chemaia, M M.. Malcolm, B A., and James, M. N. G. (1994) Nature 369, 72-76
11. Matthews, D. A., Smith, W. W , Ferre, R. A., Condon, B., Budahazi, G., Sisson, W., Villafranca, J. E., Janson, C. A., McElroy, H. E., Gribskov, C. L., and Worland, S. (1994) Cell 77, 761-771
12. Kitamura, N., Semler, B. L., Rothberg, P. G., Larsen, G. R., Adler, C J , Dorner, A. J., Emini, E. A., Hanecak, R., Lee, J. J., van der Werf, S., Anderson, C. W., and Wimmer, E. (1981) Nature 291, 547-553
13. Den Boon, J A., Snijder, E. J., Chirnside, E. D., de Vries, A. A. F., Horzinek, M. C., and Spaan, W. J. M. (1991) J. Virol. 65, 2910-2920
14. Godeny, E. K., Chen, L., Kumar, S. N., Methven, S L., Koonin, E. V., and Brinton, M. A. (1993) Virology 194, 585-596
15. Meulenberg, J. J. M., Hulst, M M., de Meijer, E. J., Moonen, P. L J M., den Besten, A., de Kluyver, E. P., Wensvoort, G., and Moormann, R. J. M. (1993) Virology 192, 62-72
16. Godeny, E K., Zeng, L , Smith, L., and Brinton, M. A. (1995) J. Virol. 69, 2679-2683
17. Snijder, E. J., and Horzinek, M. C. (1993) J. Gen. Virol. 74, 2305-2316
18. Snijder, E. J., and Spaan, W. J. M. (1995) The Coronaviruses (Siddell, S. G., ed) pp. 239-255, Plenum Press, New York
19. Snijder, E. J., Wassenaar, A. L. M., and Spaan, W. J. M. (1992) J. Virol. 66, 7040-7048
20. Snijder, E. J., Wassenaar, A. L. M., and Spaan, W. J. M. (1994) J. Virol. 68, 5755-5764
21. Den Boon, J A., Faaberg, K. S., Meulenberg, J. J. M., Wassenaar, A. L. M. Plagemann, P G. W. M., Gorbalenya, A. E., and Snijder, E. J. (1995) J. Virol. 69, 4500-4505
22. Snijder, E. J., Wassenaar, A L. M., Spaan, W. J. M., and Gorbalenya, A. E. (1995) J. Biol. Chem 270, 16671-16676
23. Altschul, S. F., Gish, W., Miller, W , Myers, E. W., and Lipman, D. J (1990) J. Mol Biol 215, 403-410
24. Sturrock, S. S., and Collins, J F. (1993) MPsrch version 1,3, Biocomputing Research Unit, University of Edinburgh, UK
25. Gorbalenya, A. E., Blinov, V. M., Donchenko, A. P., and Koonin, E. V. (1989) J. Mol. Evol 28, 256-268
26. Dayhoff, M. O., Schwartz, R M, and Orcutt, B. C. (1978) Atlas of Protein Sequence and Structure, pp. 345-352, National Biomedical Research Foundation, Washington, D. C.
27. Higgins, D. G., Bleasby, A. J., and Fuchs, R. (1992) Comput. Appl. Biosci. 8, 189-191
28. Hemkoff, S., and Henikoff, J. G. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 10915-10919
29. Leontovich, A. M., Brodsky, L. I., and Gorbalenya, A. E. (1993) BioSystems 30, 57-63
30. Sambrook, J , Fritsch, E. F., and Mamatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd Ed., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
31. Jang, S. K. Kräusslich, H. G., Nicklin, M. J. H., Duke, G. M., Palmenberg, A. C., and Wimmer, E. (1988) J. Virol 62, 2636-2643
32. Kunkel, T. A., Roberts, J. D., and Zakour, R. (1987) Methods Enzymol. 154, 367-382
33. Landt, O , Grunert, H. P., and Hahn, U. (1990) Gene (Amst.) 96, 125-128
34. Fuerst, T. R., Niles, E. G , Studier, F. W., and Moss, B. (1986) Proc. Natl. Acad. Sci. U. S A. 83, 8122-8126
35. Laemmli, U. K (1970) Nature 227, 680-685
36. Dougherty, W. G , Parks, T. D., Cary, S. M., Bazan, J. F , and Fletterick, R. J. (1989) Virology 172, 302-310
37. Garcia, J. A., Lain, S., Cervera, M. T., Riechmann, J. L., and Martin, M. T. (1990) J. Gen. Virol 71, 2773-2779
38. Hammerle, T., Hellen, C. U T., and Wimmer, E. (1991) J. Biol. Chem. 266, 5412-5416
39. Kean, K. M., Teterina, N. L., Marc, D., and Girard, M. (1991) Virology 181, 609-619
40. Dessens, J. T., and Lomonossoff, G. P. (1991) Virology 184, 738-746
41. Margis, R., and Pinck, L. (1992) Virology 190, 884-888
42. Boniotti, B., Wirblich, C., Sibilia, M., Meyers, G., Thiel, H. J., and Rossi, C. (1994) J. Virol. 68, 6487-6495
43. Ivanoff, L. A., Towatari, T., Ray, J., Korant, B. D., and Petteway, S. R. (1986) Pnoc. Natl. Acad. Sci. U. S. A. 83, 5392-5396
44. Cheah, K.-C., Leong, L. E.-C., and Porter, A. G. (1990) J. Biol. Chem. 265, 7180-7187
45. Lawson, M. A., and Semler, B. L. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 9919-9923
46. Andino, R., Rieckhof, G. E., Achacoso, P. L., and Baltimore, D. (1993) EMBO J. 12, 3587-3598
47. Hemmer, O., Greif, C., Dufoureq, P., Reinboit, J., and Fritsch, C. (1995) Virology 206, 362-371
48. Baum, E. Z., Bebernitz, G. A., Palant, O., Mueller, T., and Plotch, S. (1991) Virology 185, 140-150
49. Gorbalenya, A. E., Koonin, E. V., Blinov, V. M , and Donchenko, A. P. (1988) FEBS Lett. 236, 287-290
50. Demler, S. A., and De Zoeten, G. A. (1991) J. Gen. Virol. 72, 1819-1834
51. Jiang, B. M., Monroe, S. S., Koonin, E. V., Stine, S. E., and Glass, R. I. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 10539-10543
52. Bazan, J. B., and Fletterick, R. J. (1990) Semin. Virol. 1, 311-322
53. Goldbach, R, Le Gall, O., and Wellink, J. (1991) Semin. Virol. 2, 19-25
54. Nienaber, V. L., Breddam, K., and Birktoft, J. J. (1993) Biochemistry 32, 11469-11475
55. Svendsen, I., Jensen, M. R., and Breddam, K. (1991) FEBS Lett 292, 165-167
56. Kitadokoro, K, Tsuzuki, H., Okamoto, H., and Sato, T. (1994) Eur. J. Biochem. 224, 735-742
57. Svendsen, I., and Breddam, K. (1992) Eur. J. Biochem. 204, 165-171
58. Brenner, S. (1988) Nature 334, 528-530
59. Gorbalenya, A. E , Koonin, E. V., Donchenko, A. P., and Blinov, V. M. (1989) Nucleic Acids Res. 17, 4847-4861
60. Lee, H. J., Shieh, C. K., Gorbalenya, A. E., Koonin, E. V., La Monica, N., Tuler, J., Bagdzhadzhyan, A., and Lai, M. M. C. (1991) Virology 180, 567-582
61. Lu, Y., Lu, X., and Denison, M. R (1995) J. Virol 69, 3554-3559
62. Ziebuhr, J., Herold, J., and Siddell, S. G. (1995) J. Virol. 69, 4331-4338
63. Liu, D. X., and Brown, T D. K. (1995) Virology 209, 420-427