Receptor for macrophage colony-stimulating factor transduces a signal decreasing erythroid potential in the multipotent hematopoietic EML cell line

Experimental Hematology

Volumn 28, Issue 10, 2000, Pages 1164-1173

  Pawlak, Géraldine ^a   Grasset, Marie France ^a   Arnaud, Sylvie ^a   Blanchet, Jean Paul ^a   Mouchiroud, Guy ^a  

^a CENTRE DE GÉNÉTIQUE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Commitment; Macrophage colony stimulating factor; Multipotent cells; Signal transduction

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; COLONY STIMULATING FACTOR 1; CYTOKINE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MONOCLONAL ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C INHIBITOR; PROTEIN KINASE INHIBITOR; STEM CELL FACTOR; TRANSCRIPTION FACTOR; TYROSINE KINASE RECEPTOR; WORTMANNIN;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BURST FORMING UNIT E; CELL DIFFERENTIATION; COLONY FORMING UNIT GM; CONTROLLED STUDY; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROLYMPHOCYTE; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMAL; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE; CELL SURVIVAL; ERYTHROID PROGENITOR CELLS; GRANULOCYTES; HEMATOPOIETIC STEM CELLS; HUMAN; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; MICE; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASE C; PROTEIN-TYROSINE KINASE; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; TRANSFECTION;

EID: 0033802341     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(00)00522-1     Document Type: Article

References (46)

1. Whetton A.D., Spooncer E. Role of cytokines and extracellular matrix in the regulation of haemopoietic stem cells. Curr Opin Cell Biol. 10:1998;721.
2. Metcalf D. Lineage commitment and maturation in hematopoietic cells. the case for extrinsic regulation Blood. 92:1998;345.
3. Enver T., Heyworth C.M., Dexter T.M. Do stem cells play dice? Blood. 92:1998;348.
4. Pharr P.N., Ogawa M., Hofbauer A., Longmore G.D. Expression of an activated erythropoietin or a colony-stimulating factor 1 receptor by pluripotent progenitors enhances colony formation but does not induce differentiation. Proc Natl Acad Sci U S A. 91:1994;7482.
5. Dubart A., Feger F., Lacout C., Goncalves F., Vainchenker W., Dumenil D. Murine pluripotent hematopoietic progenitors constitutively expressing a normal erythropoietin receptor proliferate in response to erythropoietin without preferential erythroid cell differentiation. Mol Cell Biol. 14:1994;4834.
6. Lacout C., Dubart A., Vainchenker W., Dumenil D. Pluripotent hematopoietic progenitors constitutively expressing a normal erythropoietin receptor give rise to normal hematopoiesis in lethally irradiated recipient mice. Exp Hematol. 25:1996;18.
7. Goncalves F., Lacout C., Villeval J.L., Wendling F., Vainchenker W., Dumenil D. Thrombopoietin does not induce lineage-restricted commitment of Mpl-R expressing pluripotent progenitors but permits their complete erythroid and megakaryocytic differentiation. Blood. 89:1997;3544.
8. Stoffel R., Ziegler S., Ghilardi N., Ledermann B., de Sauvage F.J., Skoda R.C. Permissive role of thrombopoietin and granulocyte colony-stimulating factor receptors in hematopoietic cell fate decisions in vivo. Proc Natl Acad Sci U S A. 96:1999;698.
9. Jacob J., Haug J.S., Raptis S., Link D.C. Specific signals generated by the cytoplasmic domain of the granulocyte colony-stimulating factor (G-CSF) receptor are not required for G-CSF-dependent granulocytic differentiation. Blood. 92:1998;353.
10. Yang F.C., Watanabe S., Tsuji K.et al. Human granulocyte colony-stimulating factor (G-CSF) stimulates the in vitro and in vivo development but not commitment of primitive multipotential progenitors from transgenic mice expressing the human G-CSF receptor. Blood. 92:1998;4632.
11. Cheng T., Shen H., Giokas D., Gere J., Tenen D.G., Scadden D.T. Temporal mapping of gene expression levels during the differentiation of individual primary hematopoietic cells. Proc Natl Acad Sci U S A. 93:1996;13158.
12. Hu M., Krause D., Greaves M.et al. Multilineage gene expression precedes commitment in the hemopoietic system. Genes Dev. 11:1997;774.
13. Enver T., Greaves M. Loops, lineage, and leukemia. Cell. 94:1998;9.
14. Pawlak G., Valadoux-Delplanque C., Revol V., Bourette R.P., Blanchet J.P., Mouchiroud G. CSF-1 impairs both proliferation and differentiation signals of erythropoietin during the commitment of bipotential NFS-60 cell line to the monocytic lineage. Exp Hematol. 27:1999;797.
15. Tsai S. Differential effects of c-fms and c-kit ligands on the lineage development of the lymphohematopoietic cell line EML C1. Cancer Chemother Pharmacol. 38:1996;S58.
16. Tsai S., Bartelmez S., Sitnicka E., Collins S. Lymphohematopoietic progenitors immortalized by a retroviral vector harboring a dominant-negative retinoic acid receptor can recapitulate lymphoid, myeloid, and erythroid development. Genes Dev. 8:1994;2831.
17. Yokota T., Oritani K., Mitsui H.et al. Growth-supporting activities of fibronectin on hematopoietic stem/progenitor cells in vitro and in vivo. structural requirement for fibronectin activities of CS1 and cell-binding domains Blood. 91:1998;3263.
18. Lawson N.D., Krause D.S., Berliner N. Normal neutrophil differentiation and secondary granule gene expression in the EML and MPRO cell lines. Exp Hematol. 26:1998;1178.
19. Williams S.C., Du Y., Schwartz R.C.et al. C/EBPepsilon is a myeloid-specific activator of cytokine, chemokine, and macrophage-colony-stimulating factor receptor genes. J Biol Chem. 273:1998;13493.
20. Bourette R.P., Mouchiroud G., Ouazana R., Morle F., Godet J., Blanchet J.P. Expression of human colony-stimulating factor-1 (CSF-1) receptor in murine pluripotent hematopoietic NFS-60 cells induces long-term proliferation in response to CSF-1 without loss of erythroid differentiation potential. Blood. 81:1993;2511.
21. Shadduck R.K., Waheed A., Mangan K.F., Rosenfeld C.S. Preparation of a monoclonal antibody directed against the receptor for murine colony-stimulating factor-1. Exp Hematol. 21:1993;515.
22. Sherr C.J., Ashmun R.A., Downing J.R.et al. Inhibition of colony-stimulating factor-1 activity by monoclonal antibodies to the human CSF-1 receptor. Blood. 73:1989;1786.
23. Chen C., Okayama H. High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol. 7:1991;2745.
24. Rohrschneider L.R., Metcalf D. Induction of macrophage colony-stimulating factor-dependent growth and differentiation after introduction of the murine c-fms gene into FDC-P1 cells. Mol Cell Biol. 9:1989;5081.
25. Kato J.Y., Roussel M.F., Ashmun R.A., Sherr C.J. Transduction of human colony-stimulating factor-1 (CSF-1) receptor into interleukin-3-dependent mouse myeloid cells induces both CSF-1-dependent and factor-independent growth. Mol Cell Biol. 9:1989;4069.
26. Rothwell V.M., Rohrschneider L.R. Murine c-fms cDNA. cloning, sequence analysis and retroviral expression Oncogene Res. 1:1987;311.
27. Bourette R.P., Rohrschneider L.R. Early events in M-CSF receptor signaling. Growth Factors. 17:2000;155.
28. Bourette R.P., Myles G.M., Choi J.L., Rohrschneider L.R. Sequential activation of phoshatidylinositol 3-kinase and phospholipase C-γ2 by the M-CSF receptor is necessary for differentiation signaling. EMBO J. 16:1997;5880.
29. Fowles L.F., Martin M.L., Nelson L.et al. Persistent activation of mitogen-activated protein kinases p42 and p44 and ets-2 phosphorylation in response to colony-stimulating factor 1/c-fms signaling. Mol Cell Biol. 18:1998;5148.
30. + myelobloast cells induces their differentiation to macrophages. Mol Cell Biol. 16:1996;6851.
31. van der Geer P., Hunter T. Mutation of Tyr697, a GRB2-binding site, and Tyr721, a PI 3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblasts. EMBO J. 12:1993;5161.
32. Bourette R.P., Arnaud S., Myles G.M., Blanchet J.P., Rohrschneider L.R., Mouchiroud G. Mona, a novel hematopoietic-specific adaptor interacting with the macrophage colony-stimulating factor receptor, is implicated in monocyte/macrophage development. EMBO J. 17:1998;7273.
33. Reedijk M., Liu X., van der Geer P., Letwin K., Waterfield M.D., Hunter T. Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3′-kinase SH2 domains. a model for SH2-mediated receptor-target interactions EMBO J. 11:1992;1365.
34. Ajenjo N., Aaronson D.S., Ceballos E., Richard C., Leon J., Crespo P. Myeloid leukemia cell growth and differentiation are independent of mitogen-activated protein kinase ERK1/2 activation. J Biol Chem. 275:2000;7189.
35. Sutor S.L., Vroman B.T., Armstrong E.A., Abraham R.T., Karnitz L.M. A phosphatidylinositol 3-kinase-dependent pathway that differentially regulates c-Raf and A-Raf. J Biol Chem. 274:1999;7002.
36. Fichelson S., Freyssinier J.M., Picard F.et al. Megakaryocyte growth and development factor-induced proliferation and differentiation are regulated by thr mitogen-activated protein kinase pathway in primitive cord blood hematopoietic progenitors. Blood. 94:1999;1601.
37. Lan Z., Wu H., Li W., Wu S., Xu M., Dai W. Transforming activity of receptor tyrosine kinase tyro3 is mediated, at least in part, by the PI3 kinase-signaling pathway. Blood. 95:2000;633.
38. Mouchiroud G., Bourette R., Blanchet J.P. Expression of functional human CSF-1 receptors on mouse bone marrow erythroid progenitor cells. C R Acad Sci III. 316:1993;1290.
39. McArthur G.A., Rohrschneider L.R., Johnson G.R. Induced expression of c-fms in normal hematopoietic cells shows evidence for both conservation and lineage restriction of signal transduction in response to macrophage colony-stimulating factor. Blood. 83:1994;972.
40. Bourette R.P., Myles G.M., Carlberg K., Chen A.R., Rohrschneider L.R. Uncoupling of the proliferation and differentiation signals mediated by the murine macrophage colony-stimulating factor receptor expressed in myeloid FDC-P1 cells. Cell Growth Differ. 6:1995;631.
41. Metcalf D., Burgess A.W. Clonal analysis of progenitor cell commitment to granulocyte or macrophage production. J Cell Physiol. 111:1982;275.
42. Reith A.D., Ellis C., Lyman S.D.et al. Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase. EMBO J. 10:1991;2451.
43. Rottapel R., Reedijk M., Williams D.E.et al. The Steel/W transduction pathway. kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor Mol Cell Biol. 11:1991;3043.
44. Rossi F., McNagny K.M., Smith G., Frampton J., Graf T. Lineage commitment of transformed haematopoietic progenitors is determined by the level of PKC activity. EMBO J. 15:1996;1894.
45. Kiley S.C., Parker P.J. Differential localization of protein kinase C isozymes in U937 cells. evidence for distinct isozyme functions during monocyte differentiation J Cell Sci. 108:1995;1003.
46. Bassini A., Zauli G., Migliaccio G.et al. Lineage-restricted expression of protein kinase C isoforms in hematopoiesis. Blood. 93:1999;1178.