Sequential activation of phoshatidylinositol 3-kinase and phospholipase C-γ2 by the M-CSF receptor is necessary for differentiation signaling

EMBO Journal

Volumn 16, Issue 19, 1997, Pages 5880-5893

  Bourette, Roland P ^a,b   Myles, Gary M ^a   Choi, Jung Lim ^a   Rohrschneider, Larry R ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

^b CENTRE DE GÉNÉTIQUE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Differentiation; Fms; Phosphatidylinositol 3 kinase; Phospholipase C ; Signal transduction

Indexed keywords

CELL RECEPTOR; COLONY STIMULATING FACTOR 1; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PROTEIN SUBUNIT; PROTEIN TYROSINE KINASE;

ARTICLE; AUTOPHOSPHORYLATION; BINDING SITE; CELL DIFFERENTIATION; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVATION; ENZYME ACTIVITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL DIFFERENTIATION; CELL LINE; ENZYME ACTIVATION; ESTRENES; ISOENZYMES; MICE; PHOSPHODIESTERASE INHIBITORS; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PYRROLIDINONES; RABBITS; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; TYROSINE;

EID: 0030765053     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.19.5880     Document Type: Article

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