DNA but not topoisomerases is a target for a cytotoxic benzo[5,6]cyclohepta[b]indol-6-one derivative

Anticancer Research

Volumn 20, Issue 5, 2000, Pages 3307-3314

  Benoit, J ^a   Routier, S ^a   Merour, J Y ^a   Colson, P ^a   Houssier, C ^a   Bailly, C ^a  

^a INSERM   (France)

Author keywords

Cell cycle; Cytotoxicity; DNA binding; DNA intercalation; Sequence recognition; Topoisomerase

Indexed keywords

6 [2 (DIMETHYLAMINO)ETHYLAMINO] 3 HYDROXY 7H INDENO[2,1 C]QUINOLIN 7 ONE; CELL DNA; DNA TOPOISOMERASE; ETOPOSIDE; INDOLE DERIVATIVE; INTERCALATING AGENT;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN HL 60; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG DNA BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; INTERCALATION COMPLEX; LEUKEMIA CELL; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL CYCLE; CYCLOHEPTANES; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; DNA, NEOPLASM; HL-60 CELLS; HUMANS; MICE; MOLECULAR CONFORMATION;

EID: 0033793834     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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