Sequence-selective intercalation of antitumour bis-naphthalimides into DNA Evidence for an approach via the major groove

European Journal of Biochemistry

Volumn 240, Issue 1, 1996, Pages 195-208

  Bailly, Christian ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Bis intercalation; Bis naphthalimide; Dna footprinting; Dna major groove; Drug dna interaction

Indexed keywords

AMONAFIDE; INTERCALATING AGENT; LU 79553; MITONAFIDE; UNCLASSIFIED DRUG;

ARTICLE; DNA BINDING; DNA FOOTPRINTING; IN VITRO STUDY; INTERCALATION COMPLEX; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

AMIDES; ANIMALS; ANTINEOPLASTIC AGENTS; BASE COMPOSITION; BASE SEQUENCE; DEOXYRIBONUCLEASE I; DNA; DNA FOOTPRINTING; DNA, CIRCULAR; ESCHERICHIA COLI; HUMANS; INDICATORS AND REAGENTS; INTERCALATING AGENTS; ISOQUINOLINES; NUCLEIC ACID CONFORMATION; OSMIUM TETROXIDE; PLASMIDS; POLYMERASE CHAIN REACTION; PURINES; PYRIMIDINES; SULFURIC ACID ESTERS; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0029797006     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1996.0195h.x     Document Type: Article

References (3)

1. Atherton, S. J. & Harriman, A. (1993) Photochemistry of intercalated methylene blue: photoinduced hydrogen atom abstraction from guanine and adenine, J. Am. Chem. Soc. 115, 1816-1822.
2. Bailly, C., OhUigin, C., Rivalle, C., Bisagni, E., Héichart, J. P. & Waring, M. J. (1990) Sequence-selective binding of an ellipticine derivative to DNA, Nucleic Acids Res. 18, 6283-6291.
3. Bailly, C. & Waring, M. J. (1993) Footprinting studies on the sequence-selective binding of tilorone to DNA, Antivir. Chem. Chemother. 4, 113-126.