Roughex mediates G1 arrest through a physical association with cyclin A

Molecular and Cellular Biology

Volumn 20, Issue 21, 2000, Pages 8220-8229

  Avedisov, S N ^a   Krasnoselskaya, I ^a   Mortin, M ^a   Thomas, B J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A; CYCLIN DEPENDENT KINASE 2; HISTONE H1; PROTAMINE KINASE; REGULATOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL CYCLE G1 PHASE; CELL DIFFERENTIATION; CELL SYNCHRONIZATION; CONTROLLED STUDY; DROSOPHILA; EYE DEVELOPMENT; GROWTH REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANIMAL; BLOTTING, WESTERN; CELL NUCLEUS; CELLS, CULTURED; CONSERVED SEQUENCE; CYCLIN A; CYTOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; DROSOPHILA; EYE PROTEINS; G1 PHASE; GENE DELETION; IMMUNOHISTOCHEMISTRY; LUCIFERASE; MICROSCOPY, CONFOCAL; PHOSPHORYLATION; PHOTORECEPTORS, INVERTEBRATE; PLASMIDS; POINT MUTATION; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN KINASES; PROTEIN P34CDC2; TRANSFECTION; TWO-HYBRID SYSTEM TECHNIQUES;

DROSOPHILA;

EID: 0033776926     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.21.8220-8229.2000     Document Type: Article

References (44)

1. Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors
2. 1 phase of the cell cycle by periodic stabilization and degradation of the p25(rum1) CDK inhibitor
3. The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase
4. Cyclin-binding motifs are essential for the function of p21(CIP1)
5. 1 of the fission yeast cell cycle
6. A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis
7. Nuclear targeting sequences - A consensus?
8. Expression of Drosophila glass protein and evidence for negative regulation of its activity in nonneuronal cells by another DNA-binding protein
9. Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division
10. Mitotic domains reveal early commitment of cells in Drosophila embryos
11. Rux is a cyclin-dependent kinase inhibitor (CKI) specific for mitotic cyclin-Cdk complexes
12. p21 contains independent binding sites for cyclin and cdk2: Both sites are required to inhibit cdk2 kinase activity
13. Cyclin A is required for the onset of DNA replication in mammalian fibroblasts
14. Roughex is a dose-dependent regulator of the second meiotic division during Drosophila spermatogenesis
15. Expression of baculovirus P35 prevents cell death in Drosophila
16. How proteolysis drives the cell cycle
17. Synergistic action of Drosophila cyclins A and B during the G2-M transition
18. Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation
19. How the cyclin became a cyclin: Regulated proteolysis in the cell cycle
20. Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development
21. Expression and function of Drosophila cyclin A during embryonic cell cycle progression
22. The roles of Drosophila cyclins A and B in mitotic control
23. Exploring the role of Drosophila cyclin A in the regulation of S phase
24. Regulation of Drosophila heat shock factor trimerization: Global sequence requirements and independence of nuclear localization
25. Cyclin A is required at two points in the human cell cycle
26. Regulation of the G2 to M transition
27. Development of the Drosophila retina, a neurocrystalline lattice
28. Cyclin A-associated kinase activity is rate limiting for entrance into S phase and is negatively regulated in G1 by p27(Kip1)
29. A Drosophila G1-specific cyclin E homolog exhibits different modes of expression during embryogenesis
30. Crystal structure of the p27(Kip1) cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex
31. The B-type cyclin kinase inhibitor p40(SIC1) controls the G1 to S transition in S. cerevisiae
32. Regulation of G1 phase
33. Inhibitors of mammalian G1 cyclin-dependent kinases
34. Drosophila fizzy-related down-regulates mitotic cyclins and is required for cell proliferation arrest and entry into endocycles
35. S-phase function of Drosophila cyclin A and its downregulation in G1 phase
36. The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes
37. Cell cycle progression in the developing Drosophila eye: Roughex encodes a novel protein required for the establishment of G1
38. Roughex down-regulates G2 cyclins in G1
39. The cellular dynamics of pattern formation in the eye of Drosophila
40. Spatial and temporal patterns of neurogenesis in the central nervous system of Drosophila melanogaster
41. Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase
42. Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27
43. The beginning of pattern formation in the Drosophila compound eye: The morphogenetic furrow and the second mitotic wave
44. Coupling of the cell cycle and myogenesis through the cyclin D1-dependent interaction of MyoD with cdk4