roughex Down-regulates G2 cyclins in G1

Genes and Development

Volumn 11, Issue 10, 1997, Pages 1289-1298

  Thomas, Barbara J ^a,b   Zavitz, Kenton H ^b   Dong, Xinzhong ^b   Lane, Mary E ^e   Weigmann, Katrin ^e   Finley Jr , Russell L ^c   Brent, Roger ^d   Lehner, Christian F ^e   Zipursky, S Lawrence ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e UNIVERSITY OF BAYREUTH   (Germany)

Author keywords

Cell cycle; cyclin A; Drosophila; eye development; G1; protein stability

Indexed keywords

CYCLINE;

ARTICLE; CELL CYCLE S PHASE; CELL SYNCHRONIZATION; CELL VIABILITY; CODON USAGE; DOWN REGULATION; ENZYME STABILITY; MITOSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROCESSING;

EID: 0030923080     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.11.10.1289     Document Type: Article

References (49)

1. Alphey, L., J. Jiminez, H. White-Cooper, I. Dawson, P. Nurse, and D. Glover. 1992. twine, a cdc25 homolog that functions in the male and female germline of Drosophila. Cell 69: 977-988.
2. Amon, A., S. Irniger, and K. Nasmyth. 1994. Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle. Cell 77: 1037-1050.
3. Brand, A.H. and N. Perrimon. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415.
4. Brandeis, M. and T. Hunt. 1996. The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase. EMBO J. 15: 5280-5289.
5. cdc2 mitotic kinase. Cell 83: 1001-1009.
6. cdc2 protein kinase. Science 250: 786-791.
7. de Nooij, J.C., M.A. Letendre, and I.K. Hariharan. 1996. A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis. Cell 87: 1237-1247.
8. 1 in the developing Drosophila eye: rca1 regulates Cyclin A. Genes & Dev 11: 94-105.
9. Draetta, G. 1990. Cell cycle control in eukaryotes: Molecular mechanisms of cdc2 activation. Trends Biochem. Sci. 15: 378-382.
10. 1 to S transition in Drosophila: Cyclin E is a limiting downstream target of E2F. Genes & Dev. 9: 1456-1468.
11. Edgar, B.A. and P.H. O'Farrell. 1989. Genetic control of cell division patterns in the Drosophila embryo. Cell 57: 177-187.
12. Ellis, M.C., E.M. O'Neill, and G.M. Rubin. 1993. Expression of Drosophila glass protein and evidence for negative regulation of its activity in non-neuronal cells by another DNA-binding protein. Development 119: 855-865.
13. Estojak, J., R. Brent, and E.A. Golemis. 1995. Correlation of two-hybrid affinity data with in vitro measurements. Mol. Cell Biol 15: 5820-5829.
14. Finley, R.L., Jr. and R. Brent. 1994. Interaction mating reveals binary and ternary connections between Drosophila cell cycle regulators. Proc. Natl. Acad. Sci. 91: 12980-12984.
15. Finley, R.L., Jr., B.J. Thomas, S.L. Zipursky, and R. Brent. 1996. Isolation of Drosophila cyclin D, a protein expressed in the morphogenetic furrow before entry into S phase. Proc. Natl. Acad. Sci. 93: 3011-3015.
16. Gabrielli, B.G., M.S. Lee, D.H. Walker, H. Piwnica-Worms, and J.L. Maller. 1992. Cdc25 regulates the phosphorylation and activity of the Xenopus cdk2 protein kinase complex. J. Biol. Chem. 267: 18040-18046.
17. Girard, F., U. Strausfeld, A. Fernandez, and N.J.C. Lamb. 1991. Cyclin A is required for the onset of DNA replication in mammalian fibroblasts. Cell 67: 1169-1179.
18. Gönczy, P., B.J. Thomas, and S. DiNardo. 1994. roughex is a dose-dependent regulator of the second meiotic division during Drosophila spermatogenesis. Cell 77: 1015-1025.
19. Gu, Y., J. Rosenblatt, and D.O. Morgan. 1992. Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15. EMBO J. 11: 3995-4005.
20. Gyuris, J., E. Golemis, H. Chertkov, and R. Brent. 1993. Cdil, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell 75: 791-803.
21. Hay, B.A., T. Wolff, and G.M. Rubin. 1994. Expression of baculovirus P35 prevents cell death in Drosophila. Development 120: 2121-2129.
22. Hayashi, S. 1996. A cdc2-dependent checkpoint maintains diploidy in Drosophila. Development 122: 1051-1058.
23. Heberlein, U., C.M. Singh, A.Y. Luk, and T.J. Donohoe. 1995. Growth and differentiation in the Drosophila eye coordinated by hedgehog. Nature 373: 709-711.
24. King, R.W., P.K. Jackson, and M.W. Kirschner. 1994. Mitosis in transition. Cell 79: 563-571.
25. Knoblich, J.A., K. Sauer, L. Jones, H. Richardson, R. Saint, and C.F. Lehner. 1994. Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell 77: 107-120.
26. Kumagai, A. and W.G. Dunphy. 1991. The cdc25 protein controls tyrosine dephosphorylation of the cdc2 protein in a cell-free system. Cell 64: 903-914.
27. Lane, M.E., K. Sauer, K.Wallace, Y.N. Jan, C.F. Lehner, and H. Vassein. 1996. Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development. Cell 87: 1225-1235.
28. Lehner, C.F. and P.H. O'Farrell. 1989. Expression and function of Drosophila cyclin A during embryonic cell cycle progression. Cell 56: 957-968.
29. Lehner, C.F., N. Yakubovitch, and P.H. O'Farrell. 1991. Exploring the role of Drosophila cyclin A in the regulation of S phase. Cold Spring Harbor Symp. Quant. Biol. 56: 465-475.
30. Lindsley, D.L. and G.G. Zimm. 1992. The genome of Drosophila melanogaster. Academic Press, San Diego, CA.
31. Morgan, D.O. 1995. Principles of CDK regulation. Nature 374: 131-134.
32. Norhury, C. and P. Nurse. 1992. Animal cell cycles and their controls. Annu. Rev. Biochem. 61: 441-470.
33. Ohtsubo, M. and J.M. Roberts. 1993. Cyclin-dependent regulation of G1 in mammalian fibroblasts. Science 259: 1908-1912.
34. Pagano, M., R. Pepperkok, F. Verde, W. Ansorge, and G. Draetta. 1992. Cyclin A is required at two points in the human cell cycle. EMBO J. 11: 961-971.
35. Pirorta, V. 1988. Vectors for P-mediated transformation in Drosophila. In Vectors: A survey of molecular cloning vectors and their uses (ed. R.L. Rodriguez and D.T. Denhardt), pp. 437-456. Butterworth, Boston, MA.
36. Resnitzky, D., M. Gossen, H. Bujard, and S.I. Reed. 1994. Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system. Mol. Cell. Biol. 14: 1669-1679.
37. Kip1. Mol. Cell. Biol. 15: 4347-4352.
38. Richardson, H.E., L.V. O'Keefe, S.I. Reed, and R. Saint. 1993. A Drosophila G1-specific cyclin E homolog exhibits different modes of expression during embryogenesis. Development 119: 673-690.
39. Richardson, H., L.V. O'Keefe, T. Marty, and R. Saint. 1995. Ectopic cyclin E expression induces premature entry into S phase and disrupts pattern formation in the Drosophila eye imaginal disc. Development 121: 3371-3379.
40. + functions as an inducer in the mitotic control of fission yeast. Cell 45: 145-153.
41. Sauer, K., J.A. Knoblich, H. Richardson, and C.F. Lehner. 1995. Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis. Genes & Dev. 9: 1327-1339.
42. SIC1 controls the G1 to S transition in S. cerevisiae. Cell 79: 233-244.
43. Sherr, C.J. 1994. G1 phase progression: Cycling on cue. Cell 79: 551-555.
44. Swenson, K.I., K.M. Farrell, and J.V. Ruderman. 1986. The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes. Cell 47: 861-870.
45. Thomas, B.J. and S.L. Zipursky. 1994. Early pattern formation in the developing Drosophila eye. Trends Cell Biol. 4: 389-394.
46. Thomas, B.J., D.A. Gunning, J. Cho, and S.L. Zipursky. 1994. Cell cycle progression in the developing Drosophila eye: roughex encodes a novel protein required for the establishment of G1. Cell 77: 1003-1014.
47. Thummel, C.S., A.M. Boulet, and H.D. Lipshitz. 1988. Vectors for Drosophila P element-mediated transformation and tissue culture transformation. Gene 74: 445-456.
48. Tomlinson, A. 1985. The cellular dynamics of pattern formation in the eye of Drosophila. J. Embryol. Exp. Morphol. 89: 313-331.
49. Whitfield, W.G.F., C. Gonzalez, G. Maldonado-Codina, and D.M. Glover. 1990. The A- and B- type cyclins of Drosophila are accumulated and destroyed in temporally distinct events that define separable phases of the G2-M transition. EMBO J. 9: 2563-2572.