Tumour necrosis factor-alpha (TNF-α) enhances lymphocyte migration into rheumatoid synovial tissue transplanted into severe combined immunodeficient (SCID) mice

Clinical and Experimental Immunology

Volumn 122, Issue 1, 2000, Pages 133-142

  Wahid, S ^a   Blades, M C ^a   De Lord, D ^a   Brown, I ^a   Blake, G ^a   Yanni, G ^a   Haskard, D O ^a,b   Panayi, G S ^a   Pitzalis, C ^a,c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c GUY S HOSPITAL   (United Kingdom)

Author keywords

Adhesion molecules; In viva SCID model; Lymphocyte migration tumour necrosis factor alpha; Rheumatoid arthritis

Indexed keywords

CELL ADHESION MOLECULE; CYTOKINE; INDIUM 111; INTERCELLULAR ADHESION MOLECULE 1; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL MODEL; ARTHRITIS; ARTICLE; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTER; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOLOGY; IMMUNOMODULATION; INFLAMMATION; ISOTOPE LABELING; LYMPHOCYTE MIGRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RHEUMATIC DISEASE; RHEUMATOID ARTHRITIS; SCID MOUSE; SYNOVIUM; TISSUE TRANSPLANTATION;

ANIMALS; ARTHRITIS, RHEUMATOID; CELL MOVEMENT; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; KINETICS; LYMPHOCYTES; MICE; MICE, SCID; SYNOVIAL MEMBRANE; TISSUE SURVIVAL; TISSUE TRANSPLANTATION; TRANSPLANTATION IMMUNOLOGY; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0033776395     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2000.01342.x     Document Type: Article

References (36)

1. Role of adhesion mechanisms in the pathogenesis of chronic synovitis. (The Michael Mason Prize Essay 1996)
2. Cell adhesion molecules in rheumatoid arthritis
3. Angiogenesis: Implications for rheumatoid arthritis
4. Invasive fibroblast-like synoviocytes in rheumatoid arthritis. Passive responders or transformed aggressors?
5. Expression of HLA-DR, DQ and DP antigens and interleukin-2 receptor on synovial fluid T lymphocyte subsets in rheumatoid arthritis: Evidence for 'frustrated' activation
6. Abnormal distribution of the helper-inducer and suppressor-inducer T-lymphocyte subsets in the rheumatoid joint
7. Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity
8. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
9. Leucocyte-endothelial interactions and regulation of leucocyte migration
10. How do lymphocytes know where to go: Current concepts and enigmas of lymphocyte homing
11. Endothelial-dependent mechanisms of leukocyte adhesion in inflammation and atherosclerosis
12. Tumor necrosis factor alpha (TNF-alpha)-induced cell adhesion to human endothelial cells is under dominant control of one TNF receptor type, TNF-R55
13. Crucial role of 55-kilodalton TNF receptor in TNF-induced adhesion molecule expression and leukocyte organ infiltration
14. Dissection of the pathologies induced by transmembrane and wild-type tumor necrosis factor in transgenic mice
15. Combination therapy in mice: What can we learn that may be useful for understanding rheumatoid arthritis
16. TNF alpha is an effective therapeutic target for rheumatoid arthritis
17. Cytokine expression and networks in rheumatoid arthritis: Rationale for anti-TNF alpha antibody therapy and its mechanism of action
18. Taming TNF: Strategies to restrain this proinflammatory cytokine
19. Anti-tumor necrosis factor-alpha therapy of rheumatoid arthritis
20. Inhibitors of tumor necrosis factor for rheumatoid arthritis
21. New tumor necrosis factor-alpha biologic therapies for rheumatoid arthritis
22. Decrease in cellularity and expression of adhesion molecules by anti-tumor necrosis factor alpha monoclonal antibody treatment in patients with rheumatoid arthritis
23. Engraftment of human synovium into severe combined immune deficient mice. Migration of human peripheral blood T cells to engrafted human synovium and to mouse lymph nodes
24. Mononuclear cell retention in rheumatoid synovial tissue engrafted in severe combined immunodeficient (SCID) mice is up-regulated by tumour necrosis factor-alpha (TNF-alpha) and mediated through intercellular adhesion molecule-1 (ICAM-1)
25. A new model for rheumatoid arthritis generated by engraftment of rheumatoid synovial tissue and normal human cartilage into scid mice
26. Cutaneous lymphocyte antigen-positive T lymphocytes preferentially migrate to the skin but not to the joint in psoriatic arthritis
27. The preferential accumulation of helper-inducer T lymphocytes in inflammatory lesions: Evidence for regulation by selective endothelial and homotypic adhesion
28. Endothelial leukocyte adhesion molecule 1: An inducible receptor for neutrophils related to complement regulatory proteins and lectins
29. Selectins
30. TNF blockade in rheumatoid arthritis: Implications for therapy and pathogenesis
31. Modulation of angiogenic vascular endothelial growth factor by tumor necrosis factor alpha and interleukin-1 in rheumatoid arthritis
32. Cytokine-inducible growth factor gene expression in human umbilical endothelial cells
33. Homing of naive, memory and effector lymphocytes
34. Tissue-specific migration pathways by phenotypically distinct subpopulations of memory T cells
35. A unique phenotype of skin-associated lymphocytes in humans. Preferential expression of the HECA-452 epitope by benign and malignant T cells at cutaneous sites
36. The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells