메뉴 건너뛰기




Volumn 59, Issue 4, 1996, Pages 518-525

Dissection of the pathologies induced by transmembrane and wild-type tumor necrosis factor in transgenic mice

Author keywords

Arthritis; Autoimmunity; Cytokine; Disease models; Inflammation; Neuroimmunology

Indexed keywords

CYTOKINE; INTERLEUKIN 1; TUMOR NECROSIS FACTOR;

EID: 9344235021     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.59.4.518     Document Type: Review
Times cited : (38)

References (94)
  • 1
    • 0026717674 scopus 로고
    • The pathophysiology of tumor necrosis factors
    • Vassalli, P. (1992) The pathophysiology of tumor necrosis factors. Annu. Rev. Immunol. 10, 411-452.
    • (1992) Annu. Rev. Immunol. , vol.10 , pp. 411-452
    • Vassalli, P.1
  • 2
    • 0024281428 scopus 로고
    • A novel form of TNF-α/cachectin is a cell surface cytoloxic transmembrane protein: Ramifications for the complex physiology of TNF-α
    • Kriegler, M., Perez, C., Defay, K., Albert, I., Lu, S. D. (1988) A novel form of TNF-α/cachectin is a cell surface cytoloxic transmembrane protein: ramifications for the complex physiology of TNF-α. Cell 53, 45-53.
    • (1988) Cell , vol.53 , pp. 45-53
    • Kriegler, M.1    Perez, C.2    Defay, K.3    Albert, I.4    Lu, S.D.5
  • 3
    • 0024360816 scopus 로고
    • Cell surface tumor necrosis factor (TNF-α) accounts for monocyte- And lymphocyte-mediated killing of TNF-α-resistant target cells
    • Peck, R., Brockhaus, M., Frey, J. R. (1989) Cell surface tumor necrosis factor (TNF-α) accounts for monocyte- and lymphocyte-mediated killing of TNF-α-resistant target cells. Cell. Immunol. 122, 1-10.
    • (1989) Cell. Immunol. , vol.122 , pp. 1-10
    • Peck, R.1    Brockhaus, M.2    Frey, J.R.3
  • 4
    • 0027322559 scopus 로고
    • + T cell clones provides a costimulatory signal for human B cell activation
    • + T cell clones provides a costimulatory signal for human B cell activation. J. Exp. Med. 177, 1575-1585.
    • (1993) J. Exp. Med. , vol.177 , pp. 1575-1585
    • Aversa, G.1    Punnonen, J.2    De Vries, J.E.3
  • 5
    • 0027287507 scopus 로고
    • Membrane tumour necrosis factor-α is involved in the polyclonal B-cell activation induced by HIV-infected human T cells
    • Macchia, D., Almerigogna, F., Parronchi, P., Ravina, A., Maggi, E., Romagnani, S. (1993) Membrane tumour necrosis factor-α is involved in the polyclonal B-cell activation induced by HIV-infected human T cells. Nature 363, 464.
    • (1993) Nature , vol.363 , pp. 464
    • Macchia, D.1    Almerigogna, F.2    Parronchi, P.3    Ravina, A.4    Maggi, E.5    Romagnani, S.6
  • 7
    • 0029007855 scopus 로고
    • The TNF-α receptor 1-associated protein TRADD signals cell death and NF-κB activation
    • Hsu, H., Xiong, J., Goeddel, D. V. (1995) The TNF-α receptor 1-associated protein TRADD signals cell death and NF-κB activation. Cell 81, 495-504.
    • (1995) Cell , vol.81 , pp. 495-504
    • Hsu, H.1    Xiong, J.2    Goeddel, D.V.3
  • 8
    • 0028124428 scopus 로고
    • A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor
    • Rothe, M., Wong, S. C., Henzel, W. J., Goeddel, D. V. (1994) A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor. Cell 78, 681-692.
    • (1994) Cell , vol.78 , pp. 681-692
    • Rothe, M.1    Wong, S.C.2    Henzel, W.J.3    Goeddel, D.V.4
  • 9
    • 0027308663 scopus 로고
    • Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF-α receptor
    • Tartaglia, L. A., Rothe, M., Hu, Y. F., Goeddel, D. V. (1993) Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF-α receptor. Cell 73, 213-216.
    • (1993) Cell , vol.73 , pp. 213-216
    • Tartaglia, L.A.1    Rothe, M.2    Hu, Y.F.3    Goeddel, D.V.4
  • 10
    • 0027327619 scopus 로고
    • Mice lacking the tumour necrosis factor receptor I are resistant to TNF-α-mediated toxicity but highly susceptible to infection by Listeria monocytogenes
    • Rothe, J., Lesslauer, W., Lotscher, H., Lang, Y., Koebel, P., Kontgen, F., Althage, A., Zinkernagel, R., Steinmetz, M., Bluethmann, H. (1993) Mice lacking the tumour necrosis factor receptor I are resistant to TNF-α-mediated toxicity but highly susceptible to infection by Listeria monocytogenes. Nature [London] 364, 798-802.
    • (1993) Nature [London] , vol.364 , pp. 798-802
    • Rothe, J.1    Lesslauer, W.2    Lotscher, H.3    Lang, Y.4    Koebel, P.5    Kontgen, F.6    Althage, A.7    Zinkernagel, R.8    Steinmetz, M.9    Bluethmann, H.10
  • 11
    • 0027275490 scopus 로고
    • A novel domain within the 55 kd TNF-α receptor signals cell death
    • Tartaglia, L. A., Ayres, T. M., Wong, G. H., Goeddel, D. V. (1993) A novel domain within the 55 kd TNF-α receptor signals cell death. Cell 74, 845-853.
    • (1993) Cell , vol.74 , pp. 845-853
    • Tartaglia, L.A.1    Ayres, T.M.2    Wong, G.H.3    Goeddel, D.V.4
  • 12
    • 0025098536 scopus 로고
    • Characterization of binding and biological effects of monoclonal antibodies against a human tumor necrosis factor receptor
    • Espevik, T., Brockhaus, M., Loetscher, H., Nonstad, U., Shalaby, R. (1990) Characterization of binding and biological effects of monoclonal antibodies against a human tumor necrosis factor receptor. J. Exp. Med. 171, 415-426.
    • (1990) J. Exp. Med. , vol.171 , pp. 415-426
    • Espevik, T.1    Brockhaus, M.2    Loetscher, H.3    Nonstad, U.4    Shalaby, R.5
  • 16
    • 0026516744 scopus 로고
    • Stabilisation of the bioactivity of tumor necrosis factor by its soluble receptors
    • Aderka, D., Engelmann, H., Maor, Y., Brakebusch, C., Wallach, D. (1992) Stabilisation of the bioactivity of tumor necrosis factor by its soluble receptors. J. Exp. Med. 175, 323-329.
    • (1992) J. Exp. Med. , vol.175 , pp. 323-329
    • Aderka, D.1    Engelmann, H.2    Maor, Y.3    Brakebusch, C.4    Wallach, D.5
  • 17
    • 0023058975 scopus 로고
    • A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation
    • Shaw, G., Kamen, R. (1986) A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46, 659-667.
    • (1986) Cell , vol.46 , pp. 659-667
    • Shaw, G.1    Kamen, R.2
  • 18
    • 0025098538 scopus 로고
    • Endotoxin-responsive sequences control cachectin/tumor necrosis factor at the translational level
    • Han, J., Brown, T., Beutler, B. (1990) Endotoxin-responsive sequences control cachectin/tumor necrosis factor at the translational level. J. Exp. Med. 171, 465-475.
    • (1990) J. Exp. Med. , vol.171 , pp. 465-475
    • Han, J.1    Brown, T.2    Beutler, B.3
  • 19
    • 0024432688 scopus 로고
    • Translational blockade imposed by cytokine-derived UA-rich sequences
    • Kruys, V., Marinx, O., Shaw, G., Deschamps, J., Huez, G. (1989) Translational blockade imposed by cytokine-derived UA-rich sequences. Science 245, 852-855.
    • (1989) Science , vol.245 , pp. 852-855
    • Kruys, V.1    Marinx, O.2    Shaw, G.3    Deschamps, J.4    Huez, G.5
  • 20
    • 0025756330 scopus 로고
    • Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific
    • Lewis, M., Tartaglia, L. A., Lee, A., Bennett, G. L., Rice, G. C., Wong, G. H. W., Chen, E. Y., Goeddel, D. V. (1991) Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific. Proc. Natl. Acad. Sci. USA 88, 2830-2834.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 2830-2834
    • Lewis, M.1    Tartaglia, L.A.2    Lee, A.3    Bennett, G.L.4    Rice, G.C.5    Wong, G.H.W.6    Chen, E.Y.7    Goeddel, D.V.8
  • 21
    • 0025149247 scopus 로고
    • A non-secretable cell surface mutant of tumour necrosis factor (TNF-α) kills by cell to cell contact
    • Perez, C., Albert, I., DeFay, K., Zachanades, N., Gooding, L., Kriegler, M. (1990) A non-secretable cell surface mutant of tumour necrosis factor (TNF-α) kills by cell to cell contact. Cell 63, 251-258.
    • (1990) Cell , vol.63 , pp. 251-258
    • Perez, C.1    Albert, I.2    DeFay, K.3    Zachanades, N.4    Gooding, L.5    Kriegler, M.6
  • 22
    • 0023712236 scopus 로고
    • Detection of tumor necrosis factor α but not tumor necrosis factor β in rheumatoid arthritis synovial fluid and serum
    • Saxne, T., Palladino, M. A., Heinegard, D., Talal, N., Wollheim, F. A. (1988) Detection of tumor necrosis factor α but not tumor necrosis factor β in rheumatoid arthritis synovial fluid and serum. Arthr. Rheumatol. 31, 1041-1045.
    • (1988) Arthr. Rheumatol. , vol.31 , pp. 1041-1045
    • Saxne, T.1    Palladino, M.A.2    Heinegard, D.3    Talal, N.4    Wollheim, F.A.5
  • 23
    • 0023764989 scopus 로고
    • Cytokines in synovial fluid: II. The presence of tumour necrosis factor and interferon
    • Hopkins, S. J., Meager, A. (1988) Cytokines in synovial fluid: II. The presence of tumour necrosis factor and interferon. Clin. Exp. Immunol. 73, 88-92.
    • (1988) Clin. Exp. Immunol. , vol.73 , pp. 88-92
    • Hopkins, S.J.1    Meager, A.2
  • 24
    • 0024380313 scopus 로고
    • Characteristics of tumor necrosis factor production in rheumatoid arthritis
    • Yocum, D. E., Esparza, L., Dubry, S., Benjamin, J. B., Volz, R., Scuderi, P. (1989) Characteristics of tumor necrosis factor production in rheumatoid arthritis. Cell. Immunol. 122, 131-145.
    • (1989) Cell. Immunol. , vol.122 , pp. 131-145
    • Yocum, D.E.1    Esparza, L.2    Dubry, S.3    Benjamin, J.B.4    Volz, R.5    Scuderi, P.6
  • 25
    • 0024063321 scopus 로고
    • Synovial localization of tumor necrosis factor in patients with rheumatoid arthritis
    • Husby, G., Williams, R. C. (1988) Synovial localization of tumor necrosis factor in patients with rheumatoid arthritis. J. Autoimmun. 1, 363-371.
    • (1988) J. Autoimmun. , vol.1 , pp. 363-371
    • Husby, G.1    Williams, R.C.2
  • 26
    • 0023773031 scopus 로고
    • Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: Prolonged production of IL-1 α
    • Buchan, G., Barrett, K., Turner, M., Chantry, D., Maini, R. N., Feldmann, M. (1988) Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1 α. Clin. Exp. Immunol. 73, 449-455.
    • (1988) Clin. Exp. Immunol. , vol.73 , pp. 449-455
    • Buchan, G.1    Barrett, K.2    Turner, M.3    Chantry, D.4    Maini, R.N.5    Feldmann, M.6
  • 27
    • 0025696128 scopus 로고
    • Analysis of IL-1 and TNF-α gene expression in human rheumatoid synoviocytes and normal monocytes by in situ hybridization
    • Macnaul, K. W., Hutchinson, N. I., Parsons, J. N., Bayne, E. K., Tocci, M. J. (1990) Analysis of IL-1 and TNF-α gene expression in human rheumatoid synoviocytes and normal monocytes by in situ hybridization. J. Immunol. 145, 4154-4166.
    • (1990) J. Immunol. , vol.145 , pp. 4154-4166
    • Macnaul, K.W.1    Hutchinson, N.I.2    Parsons, J.N.3    Bayne, E.K.4    Tocci, M.J.5
  • 28
    • 0026749602 scopus 로고
    • Enhanced expression of tumor necrosis factor receptor mRNA and protein in mononuclear cells isolated from rheumatoid arthritis synovial joints
    • Brennan, F. M., Gibbons, D. L., Mitchell, T., Cope, A. P., Maini, R. N., Feldmann, M. (1992) Enhanced expression of tumor necrosis factor receptor mRNA and protein in mononuclear cells isolated from rheumatoid arthritis synovial joints. Eur. J. Immunol. 22, 1907-1912.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 1907-1912
    • Brennan, F.M.1    Gibbons, D.L.2    Mitchell, T.3    Cope, A.P.4    Maini, R.N.5    Feldmann, M.6
  • 29
    • 0023767680 scopus 로고
    • Stimulation of human synovial fibroblast DNA synthesis by recombinant human cytokines
    • Butler, D. M., Piccoli, D. S., Hart, P. H., Hamilton, J. A. (1988) Stimulation of human synovial fibroblast DNA synthesis by recombinant human cytokines. J. Rheumatol. 15, 1463-1470.
    • (1988) J. Rheumatol. , vol.15 , pp. 1463-1470
    • Butler, D.M.1    Piccoli, D.S.2    Hart, P.H.3    Hamilton, J.A.4
  • 30
    • 0024504366 scopus 로고
    • Characteristics of human synovial fibroblast activation by IL-1β and TNF-α
    • Gitter, B. D., Labus, J. M., Lees, S. L., Scheetz, M. E. (1989) Characteristics of human synovial fibroblast activation by IL-1β and TNF-α. Immunology 66, 196-200.
    • (1989) Immunology , vol.66 , pp. 196-200
    • Gitter, B.D.1    Labus, J.M.2    Lees, S.L.3    Scheetz, M.E.4
  • 31
    • 0022296893 scopus 로고
    • 2 production by human synovial cells and dermal fibroblasts
    • 2 production by human synovial cells and dermal fibroblasts. J. Exp. Med. 162, 2163-2168.
    • (1985) J. Exp. Med. , vol.162 , pp. 2163-2168
    • Dayer, J.M.1    Beutler, B.2    Cerami, A.3
  • 33
    • 0022394427 scopus 로고
    • Pig interleukin 1. Purification of two immunologically different leukocyte proteins that cause cartilage resorption, lymphocyte activation and fever
    • Saklatvala, J., Sarsfield, S. J., Townsend, Y. (1985) Pig interleukin 1. Purification of two immunologically different leukocyte proteins that cause cartilage resorption, lymphocyte activation and fever. J. Exp. Med. 162, 1208-1222.
    • (1985) J. Exp. Med. , vol.162 , pp. 1208-1222
    • Saklatvala, J.1    Sarsfield, S.J.2    Townsend, Y.3
  • 34
    • 0022441214 scopus 로고
    • Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage
    • Saklatvala, J. (1986) Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage. Nature 322, 547-549.
    • (1986) Nature , vol.322 , pp. 547-549
    • Saklatvala, J.1
  • 35
    • 0022648104 scopus 로고
    • Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors
    • Bertolini, D. R., Nedwin, G. E., Bringman, T. S., Smith, D. D., Mundy, G. R. (1986) Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors. Nature [London] 319, 516-518.
    • (1986) Nature [London] , vol.319 , pp. 516-518
    • Bertolini, D.R.1    Nedwin, G.E.2    Bringman, T.S.3    Smith, D.D.4    Mundy, G.R.5
  • 37
    • 0024314554 scopus 로고
    • Inhibitory effect of TNF-α antibodies on synovial cell interleukin-1 production in rheumatoid arthritis
    • Brennan, F. M., Chantry, D., Jackson, A., Maini, R., Feldmann, M. (1989) Inhibitory effect of TNF-α antibodies on synovial cell interleukin-1 production in rheumatoid arthritis. Lancet 2, 244-247.
    • (1989) Lancet , vol.2 , pp. 244-247
    • Brennan, F.M.1    Chantry, D.2    Jackson, A.3    Maini, R.4    Feldmann, M.5
  • 38
    • 0025939257 scopus 로고
    • Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: Regulation by tumor necrosis factor-α
    • Haworth, C., Brennan, F. M., Chantry, D., Turner, M., Maini, R. N., Feldmann, M. (1991) Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: regulation by tumor necrosis factor-α. Eur. J. Immunol. 21, 2575-2579.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2575-2579
    • Haworth, C.1    Brennan, F.M.2    Chantry, D.3    Turner, M.4    Maini, R.N.5    Feldmann, M.6
  • 39
    • 0028144871 scopus 로고
    • The role of tumour necrosis factor-alpha and IL-1 in polymorphonuclear leucocyte and T lymphocyte recruitment to joint inflammation in adjuvant arthritis
    • Issekutz, A. C., Meager, A., Otterness, I., Issekutz, T. B. (1994) The role of tumour necrosis factor-alpha and IL-1 in polymorphonuclear leucocyte and T lymphocyte recruitment to joint inflammation in adjuvant arthritis. Clin. Exp. Immunol. 97, 26-32.
    • (1994) Clin. Exp. Immunol. , vol.97 , pp. 26-32
    • Issekutz, A.C.1    Meager, A.2    Otterness, I.3    Issekutz, T.B.4
  • 40
    • 0026039673 scopus 로고
    • Transgenic mice expressing human tumour necrosis factor: A predictive genetic model of arthritis
    • Keffer, J., Probert, L., Cazlaris, H., Georgopoulos, S., Kaslaris, E., Kioussis, D., Kollias, G. (1991) Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. EMBO J. 10, 4025-4031.
    • (1991) EMBO J. , vol.10 , pp. 4025-4031
    • Keffer, J.1    Probert, L.2    Cazlaris, H.3    Georgopoulos, S.4    Kaslaris, E.5    Kioussis, D.6    Kollias, G.7
  • 41
    • 0025304539 scopus 로고
    • Rheumatoid arthritis: Pathophysiology and implications for therapy
    • Harris, E. D. (1990) Rheumatoid arthritis: pathophysiology and implications for therapy. N. Engl. J. Med. 322, 1277-1289.
    • (1990) N. Engl. J. Med. , vol.322 , pp. 1277-1289
    • Harris, E.D.1
  • 42
    • 0025241668 scopus 로고
    • Re-evaluation of the chemotactic activity of tumour necrosis factor for monocytes
    • Wang, J. M., Walter, S., Mantovani, A. (1990) Re-evaluation of the chemotactic activity of tumour necrosis factor for monocytes. Immunology 71, 364-367.
    • (1990) Immunology , vol.71 , pp. 364-367
    • Wang, J.M.1    Walter, S.2    Mantovani, A.3
  • 43
    • 0027227942 scopus 로고
    • The synovium of transgenic arthritic mice expressing human tumor necrosis factor contains a high level of nerve growth factor
    • Aloe, L., Probert, L., Kollias, G., Bracci-Laudiero, L., Spillantini, M. G., Levi-Montalcini, R. (1993) The synovium of transgenic arthritic mice expressing human tumor necrosis factor contains a high level of nerve growth factor. Growth Factors 9, 149-155.
    • (1993) Growth Factors , vol.9 , pp. 149-155
    • Aloe, L.1    Probert, L.2    Kollias, G.3    Bracci-Laudiero, L.4    Spillantini, M.G.5    Levi-Montalcini, R.6
  • 45
    • 0025253851 scopus 로고
    • Biology of multifunctional cytokines:IL-6 and related molecules (IL-1 and TNF-α)
    • Akira, S., Hirano, T., Taga, T., Kishimoto, T. (1990) Biology of multifunctional cytokines:IL-6 and related molecules (IL-1 and TNF-α). FASEB J. 4, 2860-2867.
    • (1990) FASEB J. , vol.4 , pp. 2860-2867
    • Akira, S.1    Hirano, T.2    Taga, T.3    Kishimoto, T.4
  • 46
    • 0027373406 scopus 로고
    • Neutralization of interleukin-1 β activity in vivo with a monoclonal antibody alleviates collagen-induced arthritis in DBA/1 mice and prevents the associated acute-phase response
    • Geiger, T., Towbin, H., Cosenti-Vargas, A., Zingel, O., Arnold, J., Rordorf, C., Glatt, M., Vosbeck, K. (1993) Neutralization of interleukin-1 β activity in vivo with a monoclonal antibody alleviates collagen-induced arthritis in DBA/1 mice and prevents the associated acute-phase response. Clin. Exp. Rheumatol. 11, 515-522.
    • (1993) Clin. Exp. Rheumatol. , vol.11 , pp. 515-522
    • Geiger, T.1    Towbin, H.2    Cosenti-Vargas, A.3    Zingel, O.4    Arnold, J.5    Rordorf, C.6    Glatt, M.7    Vosbeck, K.8
  • 47
    • 0028342682 scopus 로고
    • Amelioration of established murine collagen-induced arthritis with anti-IL-1 treatment
    • van den Berg, W. B., Joosten, L. A. B., Helsen, M., van de Loo, F. A. J. (1994) Amelioration of established murine collagen-induced arthritis with anti-IL-1 treatment. Clin. Exp. Immunol. 95, 237-243.
    • (1994) Clin. Exp. Immunol. , vol.95 , pp. 237-243
    • Van Den Berg, W.B.1    Joosten, L.A.B.2    Helsen, M.3    Van De Loo, F.A.J.4
  • 48
  • 49
    • 0029045458 scopus 로고
    • The type I interleukin-1 receptor acts in series with tumor necrosis factor (TNF-α) to induce arthritis in TNF-α-transgenic mice
    • Probert, L., Plows, D., Kontogeorgos, G., Kollias, G. (1995) The type I interleukin-1 receptor acts in series with tumor necrosis factor (TNF-α) to induce arthritis in TNF-α-transgenic mice. Eur. J. Immunol. 25, 1794-1797.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1794-1797
    • Probert, L.1    Plows, D.2    Kontogeorgos, G.3    Kollias, G.4
  • 50
    • 0029891052 scopus 로고    scopus 로고
    • Transmembrane TNF is sufficient to induce localised tissue toxicity and chronic inflammatory arthritis in transgenic mice
    • in press
    • 49a. Georgopoulos, S., Plows, D., Kollias, G. (1996) Transmembrane TNF is sufficient to induce localised tissue toxicity and chronic inflammatory arthritis in transgenic mice. J. Inflamm, in press.
    • (1996) J. Inflamm
    • Georgopoulos, S.1    Plows, D.2    Kollias, G.3
  • 52
    • 0023127850 scopus 로고
    • Immunoregulatory activity of recombinant human tumor necrosis factor (TNF-α): Induction of TNF-α receptors on human T cells and TNF-α-mediated enhancement of T cell responses
    • Sheurich, P., Thoma, B., Ucer, U., Pfizenmaier, K. (1987) Immunoregulatory activity of recombinant human tumor necrosis factor (TNF-α): induction of TNF-α receptors on human T cells and TNF-α-mediated enhancement of T cell responses. J. Immunol. 138, 1786-1790.
    • (1987) J. Immunol. , vol.138 , pp. 1786-1790
    • Sheurich, P.1    Thoma, B.2    Ucer, U.3    Pfizenmaier, K.4
  • 53
    • 0027281373 scopus 로고
    • A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen
    • Itoh, N., Nagata, S. (1993) A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen. J. Biol. Chem. 268, 10932-10937.
    • (1993) J. Biol. Chem. , vol.268 , pp. 10932-10937
    • Itoh, N.1    Nagata, S.2
  • 54
    • 0025737582 scopus 로고
    • Tumor necrosis factor receptors in lymphoid tissues and lymphomas
    • Ryffel, B., Brockhaus, M., Durmuller, U., Gudat, F. (1991) Tumor necrosis factor receptors in lymphoid tissues and lymphomas. Am. J. Pathol. 139, 7-15.
    • (1991) Am. J. Pathol. , vol.139 , pp. 7-15
    • Ryffel, B.1    Brockhaus, M.2    Durmuller, U.3    Gudat, F.4
  • 55
    • 0028964310 scopus 로고
    • The mouse/human chimeric monoclonal antibody cA2 neutralizes TNF-α in vitro and protects transgenic mice from cachexia and TNF-α lethality in vivo
    • Siegel, S. A., Shealy, D. J., Nakada, M. T., Le, J., Woulfe, D. S., Probert, L., Kollias, G., Ghrayeb, J., Vilcek, J., Daddona, P. E. (1995) The mouse/human chimeric monoclonal antibody cA2 neutralizes TNF-α in vitro and protects transgenic mice from cachexia and TNF-α lethality in vivo. Cytokine 7, 15-25.
    • (1995) Cytokine , vol.7 , pp. 15-25
    • Siegel, S.A.1    Shealy, D.J.2    Nakada, M.T.3    Le, J.4    Woulfe, D.S.5    Probert, L.6    Kollias, G.7    Ghrayeb, J.8    Vilcek, J.9    Daddona, P.E.10
  • 56
    • 0022553592 scopus 로고
    • Recombinant tumor necrosis factor and immune interferon act singly and in combination to reorganize human vascular endothelial cell monolayers
    • Stolpen, A. H., Guinan, E. C., Fiers, W., Pober, J. S. (1986) Recombinant tumor necrosis factor and immune interferon act singly and in combination to reorganize human vascular endothelial cell monolayers. Am. J. Pathol. 123, 16-24.
    • (1986) Am. J. Pathol. , vol.123 , pp. 16-24
    • Stolpen, A.H.1    Guinan, E.C.2    Fiers, W.3    Pober, J.S.4
  • 57
    • 0142164496 scopus 로고
    • Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor
    • Gamble, J. R., Harlan, J. M., Klebanoff, S. J., Vadas, M. A. (1985) Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor. Proc. Natl. Acad. Sci. USA 82, 8667-8671.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 8667-8671
    • Gamble, J.R.1    Harlan, J.M.2    Klebanoff, S.J.3    Vadas, M.A.4
  • 58
    • 0023226325 scopus 로고
    • Induction of an activation antigen on postcapillary venular endothelium in human skin organ culture
    • Messadi, D. V., Pober, J. S., Fiers, W., Gimbrone, M. A., Murphy, G. F. (1987) Induction of an activation antigen on postcapillary venular endothelium in human skin organ culture. J. Immunol. 139, 1557-1562.
    • (1987) J. Immunol. , vol.139 , pp. 1557-1562
    • Messadi, D.V.1    Pober, J.S.2    Fiers, W.3    Gimbrone, M.A.4    Murphy, G.F.5
  • 59
    • 0022494648 scopus 로고
    • Endotoxin and tumor necrosis factor induce interleukin-1 gene expression in adult human vascular endothelial cells
    • Libby, P., Ordovas, J. M., Auger, K. R., Bobbins, A. H., Birinyi, L. K., Dinarello, C. A. (1986) Endotoxin and tumor necrosis factor induce interleukin-1 gene expression in adult human vascular endothelial cells. Am. J. Pathol. 124, 179-185.
    • (1986) Am. J. Pathol. , vol.124 , pp. 179-185
    • Libby, P.1    Ordovas, J.M.2    Auger, K.R.3    Bobbins, A.H.4    Birinyi, L.K.5    Dinarello, C.A.6
  • 60
    • 0022508582 scopus 로고
    • Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1
    • Nawroth, P. P., Bank, I., Handley, D., Cassimeris, J., Chess, L., Stern, D. (1986) Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1. J. Exp. Med. 163, 1363.
    • (1986) J. Exp. Med. , vol.163 , pp. 1363
    • Nawroth, P.P.1    Bank, I.2    Handley, D.3    Cassimeris, J.4    Chess, L.5    Stern, D.6
  • 61
    • 0022601049 scopus 로고
    • Modulation of endothelial cell hemostatic properties by tumor necrosis factor
    • Nawroth, P. P., Stern, D. M. (1986) Modulation of endothelial cell hemostatic properties by tumor necrosis factor. J. Exp. Med. 163, 740-745.
    • (1986) J. Exp. Med. , vol.163 , pp. 740-745
    • Nawroth, P.P.1    Stern, D.M.2
  • 62
    • 0000555820 scopus 로고
    • Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: Characterization and comparison with the actions of interleukin 1
    • Bevilacqua, M. P., Pober, J. S., Majeau, G. R., Fiers, W., Cotran, R. S., Gimbrone, M. A. (1986) Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1. Proc. Natl. Acad. Sci. USA 83, 4533-4537.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 4533-4537
    • Bevilacqua, M.P.1    Pober, J.S.2    Majeau, G.R.3    Fiers, W.4    Cotran, R.S.5    Gimbrone, M.A.6
  • 64
    • 0022411888 scopus 로고
    • Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin
    • Beutler, B., Milsark, I. W., Cerami, A. C. (1985) Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science 229, 869-871.
    • (1985) Science , vol.229 , pp. 869-871
    • Beutler, B.1    Milsark, I.W.2    Cerami, A.C.3
  • 69
    • 0027483753 scopus 로고
    • Distribution and characterization of tumor necrosis factor-α-like immunoreactivity in the murine central nervous system
    • Breder, C. D., Tsujimoto, M., Terano, Y., Scott, D. W., Saper, C. B. (1993) Distribution and characterization of tumor necrosis factor-α-like immunoreactivity in the murine central nervous system. J. Comp. Neurol. 337, 543-567.
    • (1993) J. Comp. Neurol. , vol.337 , pp. 543-567
    • Breder, C.D.1    Tsujimoto, M.2    Terano, Y.3    Scott, D.W.4    Saper, C.B.5
  • 70
    • 0023937241 scopus 로고
    • Tumor necrosis factor and interleukin-1 beta: Suppression of food intake by direct action within the central nervous system
    • Plata-Salaman, C. R., Oomura, Y., Kai, Y. (1988) Tumor necrosis factor and interleukin-1 beta: suppression of food intake by direct action within the central nervous system. Brain Res. 448, 106-114.
    • (1988) Brain Res. , vol.448 , pp. 106-114
    • Plata-Salaman, C.R.1    Oomura, Y.2    Kai, Y.3
  • 71
    • 0024366885 scopus 로고
    • Tumor necrosis factor identified in multiple sclerosis brain
    • Hofman, F. M., Hinton, D. R., Johnson, K., Merrill, J. E. (1989) Tumor necrosis factor identified in multiple sclerosis brain. J. Exp. Med. 170, 607-612.
    • (1989) J. Exp. Med. , vol.170 , pp. 607-612
    • Hofman, F.M.1    Hinton, D.R.2    Johnson, K.3    Merrill, J.E.4
  • 72
    • 0025852567 scopus 로고
    • Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions
    • Selmaj, K., Raine, C. S., Cannella, B., Brosnan, C. F. (1991) Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J. Clin. Invest. 87, 949-954.
    • (1991) J. Clin. Invest. , vol.87 , pp. 949-954
    • Selmaj, K.1    Raine, C.S.2    Cannella, B.3    Brosnan, C.F.4
  • 74
    • 0023890129 scopus 로고
    • Tumor necrosis factor α in cerebrospinal fluid during bacterial, but not viral, meningitis
    • Leist, T. P., Frei, K., Kam-Hansen, S., Zinkernagel, R. M., Fontana, A. (1988) Tumor necrosis factor α in cerebrospinal fluid during bacterial, but not viral, meningitis. J. Exp. Med. 167, 1743-1748.
    • (1988) J. Exp. Med. , vol.167 , pp. 1743-1748
    • Leist, T.P.1    Frei, K.2    Kam-Hansen, S.3    Zinkernagel, R.M.4    Fontana, A.5
  • 75
    • 0028178281 scopus 로고
    • Tumor necrosis factor-α (TNF-α) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients
    • Mogi, M., Harada, M., Riederer, P., Narabayashi, H., Fujita, K., Nagatsu, T. (1994) Tumor necrosis factor-α (TNF-α) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients. Neurosci. Lett. 165, 208-210.
    • (1994) Neurosci. Lett. , vol.165 , pp. 208-210
    • Mogi, M.1    Harada, M.2    Riederer, P.3    Narabayashi, H.4    Fujita, K.5    Nagatsu, T.6
  • 76
    • 0024854758 scopus 로고
    • Tumor-necrosis factor and other cytokines in cerebral malaria: Experimental and clinical data
    • Grau, G. E., Piguet, P. -F., Vassalli, P., Lambert, P.-H. (1989) Tumor-necrosis factor and other cytokines in cerebral malaria: experimental and clinical data. Immunol. Rev. 189, 49-70.
    • (1989) Immunol. Rev. , vol.189 , pp. 49-70
    • Grau, G.E.1    Piguet, P.F.2    Vassalli, P.3    Lambert, P.-H.4
  • 77
    • 0001139213 scopus 로고
    • Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus
    • Lieberman, A. P., Pitha, P. M., Shin, H. S., Shin, M. L. (1989) Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus. Proc. Natl. Acad. Sci. USA 86, 6348-6352.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 6348-6352
    • Lieberman, A.P.1    Pitha, P.M.2    Shin, H.S.3    Shin, M.L.4
  • 78
    • 0023618311 scopus 로고
    • Antigen presentation and tumor cytotoxicity by interferon gamma treated microglial cells
    • Frei, K., Siepl, C., Groseurth, P., Bodmer, S., Schwerdel, C., Fontana, A. (1989) Antigen presentation and tumor cytotoxicity by interferon gamma treated microglial cells. Eur. J. Immunol. 19, 1271-1278.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 1271-1278
    • Frei, K.1    Siepl, C.2    Groseurth, P.3    Bodmer, S.4    Schwerdel, C.5    Fontana, A.6
  • 79
    • 0023904746 scopus 로고
    • Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro
    • Selmaj, K., Raine, C. S. (1988) Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann. Neurol. 23, 339-346.
    • (1988) Ann. Neurol. , vol.23 , pp. 339-346
    • Selmaj, K.1    Raine, C.S.2
  • 80
    • 0025827448 scopus 로고
    • Cytokine cytotoxicity against oligodendrocytes. Apoptosis induced by lymphotoxin
    • Selmaj, K., Raine, C. S., Farooq, M., Norton, W. T., Brosnan, C. F. (1991) Cytokine cytotoxicity against oligodendrocytes. Apoptosis induced by lymphotoxin. J. Immunol. 147, 1522-1529.
    • (1991) J. Immunol. , vol.147 , pp. 1522-1529
    • Selmaj, K.1    Raine, C.S.2    Farooq, M.3    Norton, W.T.4    Brosnan, C.F.5
  • 82
    • 0025000863 scopus 로고
    • An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis
    • Ruddle, N. H., Bergman, C. M., McGrath, K. M., Lingenheld, E. G., Grunnet, M. L., Padula, S. J., Clark, R. B. (1990) An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis. J. Exp. Med. 173, 1193-1200.
    • (1990) J. Exp. Med. , vol.173 , pp. 1193-1200
    • Ruddle, N.H.1    Bergman, C.M.2    McGrath, K.M.3    Lingenheld, E.G.4    Grunnet, M.L.5    Padula, S.J.6    Clark, R.B.7
  • 83
    • 0028855346 scopus 로고
    • Prevention of chronic relapsing experimental autoimmune encephalomyelitis by soluble tumor necrosis factor receptor I
    • Selmaj, K., Papiere, W., Glabinski, A., Kohno, T. (1995) Prevention of chronic relapsing experimental autoimmune encephalomyelitis by soluble tumor necrosis factor receptor I. J. Neuroimmunol. 56, 135-141.
    • (1995) J. Neuroimmunol. , vol.56 , pp. 135-141
    • Selmaj, K.1    Papiere, W.2    Glabinski, A.3    Kohno, T.4
  • 84
    • 0028864801 scopus 로고
    • Spontaneous inflammatory demyelinating disease in transgenic mice showing CNS-specific expression of tumor necrosis factor α
    • Probert, L., Akassoglou, K., Pasparakis, M., Kontogeorgos, G., Kollias, G. (1995) Spontaneous inflammatory demyelinating disease in transgenic mice showing CNS-specific expression of tumor necrosis factor α Proc. Natl. Acad. Sci. USA 92, 11294-11298.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11294-11298
    • Probert, L.1    Akassoglou, K.2    Pasparakis, M.3    Kontogeorgos, G.4    Kollias, G.5
  • 85
    • 0025787089 scopus 로고
    • Multiple sclerosis: A pivotal role for the T cell in lesion development
    • Raine, C. S. (1991) Multiple sclerosis: a pivotal role for the T cell in lesion development. Neuropathol. Appl. Neurobiol. 17, 265-274.
    • (1991) Neuropathol. Appl. Neurobiol. , vol.17 , pp. 265-274
    • Raine, C.S.1
  • 86
    • 0025246367 scopus 로고
    • The T lymphocyte in experimental allergic encephalomyelitis
    • Zamvil, S. S., Steinman, L. (1990) The T lymphocyte in experimental allergic encephalomyelitis. Annu. Rev. Immunol. 8, 579-621.
    • (1990) Annu. Rev. Immunol. , vol.8 , pp. 579-621
    • Zamvil, S.S.1    Steinman, L.2
  • 89
    • 0025773147 scopus 로고
    • Association between tumor necrosis factor- and disease progression in patients with multiple sclerosis
    • Sharief, M. K., Hentges, R. (1991) Association between tumor necrosis factor- and disease progression in patients with multiple sclerosis. N. Engl. J. Med. 325, 467-172.
    • (1991) N. Engl. J. Med. , vol.325 , pp. 467-1172
    • Sharief, M.K.1    Hentges, R.2
  • 90
    • 0027161216 scopus 로고
    • Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide
    • Merrill, J. E., Ignarro, L. J., Sherman, M. P., Melinek, J., Lane, T. E. (1993) Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J. Immunol. 151 2132-2141.
    • (1993) J. Immunol. , vol.151 , pp. 2132-2141
    • Merrill, J.E.1    Ignarro, L.J.2    Sherman, M.P.3    Melinek, J.4    Lane, T.E.5
  • 91
    • 0029057332 scopus 로고
    • Nitric oxide triggers a switch to growth arrest during differentiation of neuronal cells
    • Peunova, N., Enikolopov, G. (1995) Nitric oxide triggers a switch to growth arrest during differentiation of neuronal cells. Nature [London] 375, 68-73.
    • (1995) Nature [London] , vol.375 , pp. 68-73
    • Peunova, N.1    Enikolopov, G.2
  • 92
    • 0028066844 scopus 로고
    • Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF-α) activity within the central nervous system using monoclonal antibodies and TNF-α receptor-immunoglobulin fusion proteins
    • Baker, D., Butler, D., Scallon, B. J., O'Neill, J.K., Turk, J. L., Feldmann, M. (1994) Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF-α) activity within the central nervous system using monoclonal antibodies and TNF-α receptor-immunoglobulin fusion proteins. Eur. J. Immunol. 24, 2040-2048.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2040-2048
    • Baker, D.1    Butler, D.2    Scallon, B.J.3    O'Neill, J.K.4    Turk, J.L.5    Feldmann, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.