Regulation of ion channel expression by cytoplasmic subunits

Current Opinion in Neurobiology

Volumn 8, Issue 3, 1998, Pages 370-374

  Trimmer, James S ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; ION CHANNEL; MEMBRANE PROTEIN; POTASSIUM CHANNEL; PROTEIN SUBUNIT;

CHANNEL GATING; CYTOPLASM; NERVE CELL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY;

EID: 0032102975     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-4388(98)80063-9     Document Type: Article

References (52)

1. Catterall WA. Structure and function of voltage-gated ion channels. Annu Rev Biochem. 64:1995;493-531.
2. + transport through channel-like proteins in a number of different metazoan and protozoan systems.
3. Isom LL, De Jongh KS, Catterall WA. Auxiliary subunits of voltage-gated ion channels. Neuron. 12:1994;1183-1194.
4. Gurnett CA, Campbell KP. Transmembrane auxiliary subunits of voltage-dependent ion channels. J Biol Chem. 271:1996;27975-27978.
5. 2+ channel diversity. Annu Rev Neurosci. 17:1994;399-418.
6. 2+ channels in mammalian central neurons. Trends Neurosci. 18:1995;89-98.
7. De Waard M, Gurnett CA, Campbell KP. Structural and functional diversity of voltage-activated calcium channels. Ion Channels. 4:1996;41-87.
8. Noda M, Ikeda T, Kayano T, Suzuki H, Takeshima H, Takahashi H, Numa S. Existence of distinct sodium channel messenger RNAs in rat brain. Nature. 320:1986;188-192.
9. Noda M, Ikeda T, Suzuki H, Takeshima H, Takahashi T, Numa S. Expression of functional sodium channels from cloned cDNA. Nature. 322:1986;826-828.
10. Tanabe T, Takeshima H, Mikami A, Flockerzi V, Takahashi H, Kangawa K, Kojima M, Matsuo H, Hirose T, Numa S. Primary structure of the receptor for calcium channel blockers from skeletal muscle. Nature. 328:1987;313-318.
11. Nargeot J, Dascal N, Lester HA. Heterologous expression of calcium channels. J Membr Biol. 126:1992;97-108.
12. Grabner M, Wang Z, Hering S, Stiessnig J, Glossmann H. Transfer of 1,4-dihydropyridine sensitivity from L-type to class A (BI) calcium channels. Neuron. 16:1996;207-218.
13. 2+ channels expressed in Xenopus laevis oocytes reveal role of repeats III and IV in activation gating. J Physiol. 486:1995;131-137.
14. Dascal N, Lotan I, Karni E, Gigi A. Calcium channel currents in Xenopus oocytes injected with rat skeletal muscle RNA. J Physiol. 450:1992;469-490.
15. Tanabe T, Beam KG, Powell JA, Numa S. Restoration of excitation-contraction coupling and slow calcium current in dysgenic muscle by dihydropyridine receptor complementary DNA. Nature. 336:1988;134-139.
16. Adams BA, Tanabe T, Mikami A, Numa S. Intramembrane charge movement restored in dysgenic skeletal muscle by injection of dihydropyridine receptor cDNAs. Nature. 346:1990;569-572.
17. Birnbaumer L, Campbell KP, Catterall WA, Harpold MM, Hofmann F, Horne WA, Mori Y, Schwartz A, Snutch TP, Tanabe T, Tsien RW. The naming of voltage-gated calcium channels. Neuron. 13:1994;505-506.
18. 1 and β subunits. J Gen Physiol. 105:1995;289-305.
19. Neely A, Wei X, Olcese R, Birnbaumer L, Stefani E. Potentiation by the β subunit of the ratio of the ionic current to the charge movement in the cardiac calcium channel. Science. 262:1993;575-578.
20. 2+ channels. Biophys J. 70:1996;1285-1293.
21. Kamp TJ, Perez-Garcia MT, Marban E. Enhancement of ionic current and charge movement by coexpression of calcium channel β (1A) subunit with α (1C) subunit in a human embryonic kidney cell line. J Physiol. 492:1996;89-96.
22. Nishimura S, Takeshima H, Hofmann F, Imoto K. Requirement of the calcium channel β subunit for functional conformation. FEBS Lett. 324:1993;283-286.
23. Green WN, Millar NS. Ion-channel assembly. Trends Neurosci. 18:1995;280-287.
24. 2+ channels. J Biol Chem. 270:1995;30036-30044.
25. 2δ with any of the β subunits (β1b, β2a, β3, β4) led to a clear translocation of staining consistent with plasma membrane expression and nonpermeabilized cells now had surface expression as judged by staining with ectodomain antibodies.
26. 1S subunit.
27. 1 subunit interaction domain. J Biol Chem. 270:1995;18088-18093.
28. Schwartz LM, McCleskey EW, Almers W. Dihydropyridine receptors in muscle are voltage-dependent but most are not functional calcium channels. Nature. 314:1985;747-751.
29. 1 subunit and eliminates excitation - contraction coupling. Proc Natl Acad Sci USA. 93:1996;13961-13966.
30. 1-null cultured myotubes restores most of the aspects of normal function.
31. Dascal N. The use of Xenopus oocytes for the study of ion channels. CRC Crit Rev Biochem. 22:1987;317-387.
32. Lacerda AE, Perez-Reyes E, Wei X, Castellano A, Brown AM. T-type and N-type calcium channels of Xenopus oocytes: evidence for specific interactions with beta subunits. Biophys J. 66:1994;1833-1843.
33. Castellano A, Wei X, Birnbaumer L, Perez-Reyes E. Cloning and expression of a neuronal calcium channel β subunit. J Biol Chem. 268:1993;12359-12366.
34. Castellano A, Wei X, Birnbaumer L, Perez-Reyes E. Cloning and expression of a third calcium channel β subunit. J Biol Chem. 268:1993;3450-3455.
35. Singer D, Biel M, Lotan I, Flockerzi V, Hofmann F. The roles of the subunits in the function of the calcium channel. Science. 253:1991;1553-1557.
36. 2+ channels, β-subunit interaction may be transient in nature, as opposed to the β subunit acting as a permanent structural subunit of the complex, and that dynamic substitution of subunits could serve to modulate channel activity.
37. Dolly JO, Parcej DN. Molecular properties of voltage-gated K+ channels. J Bioenerg Biomembr. 28:1996;231-253.
38. + channels from bovine brain. Proc Natl Acad Sci USA. 91:1994;1637-1641.
39. + channels altered by presence of β-subunit. Nature. 369:1994;289-294.
40. Roeper J, Sewing S, Zhang Y, Sommer T, Wanner SG, Pongs O. NIP domain prevents N-type inactivation in voltage-gated potassium channels. Nature. 391:1998;390-393 The Kv1.6 α subunits is shown to have an inactivation-inhibiting domain at its amino terminus. Kv1.6 could then serve as a determinant of gating in complexes containing inactivating α (e.g. Kv1.4) and β (e.g., Kvβ1) subunits.
41. + channels in transfected mammalian cells. J Biol Chem. 272:1997;11728-11735.
42. + channel current kinetics.
43. + channel α- and β-subunit polypeptides in rat brain. J Neurosci. 15:1995;5360-5371.
44. + channel β subunits: expression and distribution of Kvβ1 and Kvβ2 in adult rat brain. J Neurosci. 16:1996;4846-4860.
45. + channel diversity in mammalian brain.
46. + channel protein. Evidence from the N-terminal sequence of its larger subunit. J Biol Chem. 265:1990;20094-20097.
47. + channel surface expression through effects early in biosynthesis. Neuron. 16:1996;843-852.
48. + channel subunits occurs in the ER.
49. Tamkun MM Deal KK, Lovinger DM. The brain Kv1.1 potassium channel: in vitro and in vivo studies on subunit assembly and posttranslational processing. J Neurosci. 14:1994;1666-1676.
50. + channel complexes.
51. Chouinard SW, Wilson GF, Schlimgen AK, Ganetzky B. A potassium channel β subunit related to the aldo-keto reductase superfamily is encoded by the Drosophila hyperkinetic locus. Proc Natl Acad Sci USA. 92:1995;6763-6767.
52. + channels. Biophys J. 71:1996;3167-3176.