Simian immunodeficiency virus resistance of macaques infused with interferon β-engineered lymphocytes

Journal of General Virology

Volumn 81, Issue 11, 2000, Pages 2741-2750

  Matheux, F ^a   Lauret, E ^a   Rousseau, V ^a   Larghero, J ^a   Boson, B ^a   Vaslin, B ^a   Cheret, A ^a   De Maeyer, E ^a   Dormont, D ^a   LeGrand, R ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CD2 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; COMPLEMENTARY DNA; DEOXYRIBONUCLEASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; NUCLEOCAPSID PROTEIN; VIRUS ANTIBODY; VIRUS ANTIGEN; VIRUS DNA; VIRUS PROTEIN; VIRUS RNA; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA MODIFICATION; DRUG EFFICACY; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; GENETIC ENGINEERING; GENETIC TRANSDUCTION; HEALTH STATUS; IMMUNE DEFICIENCY; IN VIVO STUDY; LYMPHOCYTE COUNT; MACACA; MALE; NONHUMAN; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; T LYMPHOCYTE SUBPOPULATION; VIRUS INFECTION; VIRUS LOAD;

ANIMALIA; DNA VIRUSES; HUMAN IMMUNODEFICIENCY VIRUS; MACACA; RNA VIRUSES; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 0033756790     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-81-11-2741     Document Type: Article

References (34)

1. Alpha interferon-induced antiretroviral activities: Restriction of viral nucleic acid synthesis and progeny virion production in human immunodeficiency virus type 1-infected monocytes
2. Gene therapy. Intracellular immunization
3. Role of interferons and other cytokines in the regulation of the immune response
4. Cytokine mRNA expression in mononuclear cells from different tissues during acute SIVmac251 infection of macaques
5. The Th1-Th2 hypothesis of HIV infection: New insights
6. Specific inhibition of viral protein synthesis in HIV-infected cells in response to interferon treatment
7. Retrovirally mediated IFN-β transduction of macrophages induces resistance to HIV, correlated with up-regulation of RANTES production and down-regulation of C-C chemokine receptor-5 expression
8. Isolation of T-cell tropic HTLV-III-like retrovirus from macaques
9. The simian immunodeficiency viruses
10. Polymorphism and gene conversion in mouse α-globin haplotypes
11. Biological effect of active anti-IFN-α immunization in HIV-infected patients
12. Acquired constitutive expression of interferon beta after gene transduction enhances human immuno-deficiency virus type 1-specific cytotoxic T lymphocyte activity by a RANTES-dependent mechanism
13. Loss of infectivity by progeny virus from alpha interferon-treated human immunodeficiency virus type 1-infected T cells is associated with defective assembly of envelope gp120
14. + T cell depletion in simian immunodeficiency virus-infected macaques
15. The role of interferons in the control of HIV replication in macrophages
16. Exploring interferon beta for gene therapy of HIV infection
17. An animal model for antilentiviral therapy: Effect of zidovudine on viral load during acute infection after exposure of macaques to simian immunodeficiency virus
18. Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques
19. Macaque lymphocytes transduced by a constitutively expressed interferon beta gene display an enhanced resistance to SIVmac251 infection
20. Host genetic influences on HIV-1 pathogenesis
21. Detection of high levels of immunoreactive human beta-1 interferon in sera from HIV-infected patients
22. How immune-based interventions can change HIV therapy
23. Immune-based therapies for treatment of HIV infection
24. Interferon-alpha but not AZT suppresses HIV expression in chronically infected cell lines
25. Control of viremia in simian immunodeficiency virus infection by CD8 + lymphocytes
26. Interferon alpha-mediated inhibition of human immunodeficiency virus type 1 provirus synthesis in T-cells
27. Induction of bystander T cell proliferation by viruses and type I interferon in vivo
28. Blocking of retroviral infection at a step prior to reverse transcription in cells transformed to constitutively express interferon beta
29. Autocrine interferon-beta synthesis for gene therapy of HIV infection: Increased resistance to HIV-1 in lymphocytes from healthy and HIV-infected individuals
30. Interferon beta transduction of peripheral blood lymphocytes from HIV-infected donors increases Th1-type cytokine production and improves the proliferative response to recall antigens
31. + T lymphocytes producing beta interferon in Hu-PBL-SCID mice controls human immunodeficiency virus infection
32. Generation of CD8 suppressor factor and β chemokines, induced by xenogeneic immunization, in the prevention of simian immunodeficiency virus infection in macaques
33. Chemokine coreceptor usage by diverse primary isolates of human immunodeficiency virus type 1