Pharmacogenetics of the arylamine N-acetyltransferases: A symposium in honor of Wendell W. Weber

Drug Metabolism and Disposition

Volumn 28, Issue 12, 2000, Pages 1425-1432

  Hein, David W ^a   Mcqueen, Charlene A ^b   Grant, Denis M ^c   Goodfellow, Geoffrey H ^c   Kadlubar, Fred F ^d   Weber, Wendell W ^e  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

^c UNIVERSITY OF TORONTO   (Canada)

^d National Center for Toxicological Research   (United States)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC AMINE; ARYLAMINE ACETYLTRANSFERASE;

ARTICLE; BIOTRANSFORMATION; BREAST CANCER; CANCER SUSCEPTIBILITY; COLON CANCER; DRUG ACETYLATION; HUMAN; NONHUMAN; PANCREAS CANCER; PHARMACOGENETICS; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 0033675835     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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2. Purification, physicochemical and kinetic properties of liver acetyl CoA: Arylamine N-acetyltransferase from rapid acetylator rabbits
3. Role of aromatic amine acetyltransferases, NAT1 and NAT2, in carcinogen-DNA adduct formation in the human urinary bladder
4. Human arylamine N-acetyltransferase genes: Isolation, chromosomal localization, and functional expression
5. Functional polymorphism of the human arylamine N-acetyltransferase gene 1 caused by C190T and G560A mutations
6. 4-Aminobiphenyl hemoglobin adducts in fetuses exposed to the tobacco smoke carcinogen in utero
7. Acetylator phenotyping: The urinary caffeine metabolite ratio in slow acetylators correlates with a marker of systemic NAT1 activity
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10. 1 male mouse
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12. Site-directed mutagenesis of recombinant human arylamine N-acetyltransferase expressed in Escherichia coli. Evidence for direct involvement of Cys68 in the catalytic mechanism of polymorphic human NAT2
13. Substrate selectivity of mouse N-acetyltransferases 1, 2, and 3 expressed in COS-1 cells
14. Characterization of a hormone response element in the mouse N-acetyltransferase 2 (Nat2*) promoter
15. Tissue- and gender-specific expression of N-acetyltransferase 2 (NAT2*) during development of the outbred mouse strain CD-1
16. The isolation and identification of a new mutagen from fried ground beef: 2-Amino-1-methyl-6-imidazo[4,5-b]pyridine (PhIP)
17. Investigation of the genetic control of sulfadiazine and isoniazid metabolism in the rabbit
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29. Update on consensus arylamine N-acetyltransferase gene nomenclature
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31. Identification and characterization of variant alleles of human NAT1 with defective function using p-aminosalicyclic acid as an in-vivo and in-vitro probe
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35. Cancer risk of heterocyclic amines in cooked foods: An analysis and implications for research
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39. Detection of a carcinogen, 2-amino-1-methyl-6-imidazo[4,5-b]pyridine (PhIP) in cigarette smoke condensate
40. Linkage of Nat and Es-1 in the mouse and development of strains congenic for N-acetyltransferase
41. Fetal N-acetyltransferase a potential role in 4-aminobiphenyl prenatal genotoxicity
42. Developmental expression of N-acetyltransferases in C57BL/6 mice
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45. 32P Postlabelling analysis of urinary mutagens from smokers of black tobacco implicates 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) as a major DNA-damaging agent
46. HPLC and GC/MS determination of 4-aminobiphenyl haemoglobin adducts in fetuses exposed to the tobacco smoke carcinogen in utero
47. Genetic control of isoniazid metabolism in man
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50. Immunochemical detection of arylamine N-acetyltransferase during mouse embryonic development in adult mouse brain
51. Human acetyltransferases
52. Acetyltransferases
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55. Involvement of Cys69 residue in the catalytic mechanism of N-hydroxyarylamine O-acetyltransferase of Salmonella typhimurium. Sequence similarity at the amino acid level suggests a common catalytic mechanism of acetyltransferase for S. typhimurium and higher organisms
56. N-Acetylation of drags: Isolation and properties of N-acetyltransferase from rabbit liver
57. The mechanism of isoniazid acetylation by human N-acetyltransferase
58. N-Acetylation pharmacogenetics
59. Relationship between NAT1 genotype and phenotype in a Japanese population
60. N-acetyltransferase 1 genetic polymorphism, cigarette smoking, well-done meat intake, and breast cancer risk