Characterization eta hormone response element in the mouse N- Acetyltransferase 2 (Nat2*) promoter

Gene Expression

Volumn 7, Issue 1, 1998, Pages 13-24

  Estrada Rodgers, Lourdes ^a   Levy, Gerald N ^a   Weber, Wendell W ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Glucocorticoids; Hormone response element Androgens; N Acetyltransferase; Promoter

Indexed keywords

ACYLTRANSFERASE; ANDROGEN; ANDROSTANOLONE; CHLORAMPHENICOL ACETYLTRANSFERASE; DEXAMETHASONE; GLUCOCORTICOID; ARYLAMINE ACETYLTRANSFERASE; DNA; HORMONE; NAT2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR SP1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; GENE EXPRESSION; GENE MAPPING; GENE STRUCTURE; HORMONAL REGULATION; HORMONE RESPONSIVE ELEMENT; KIDNEY; LIVER; MOUSE; NONHUMAN; PROMOTER REGION; REGULATOR GENE; ANIMAL; BINDING SITE; C57BL MOUSE; CELL CULTURE; ENZYMOLOGY; GENETIC TRANSCRIPTION; GENETICS; HUMAN; MALE; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; REPORTER GENE; SEXUAL DEVELOPMENT; START CODON; TATA BOX;

ANIMALIA; FELIS CATUS; MAMMALIA;

ANIMALS; ARYLAMINE N-ACETYLTRANSFERASE; BASE SEQUENCE; BINDING SITES; CELLS, CULTURED; CODON, INITIATOR; DNA; GENES, REPORTER; HORMONES; HUMANS; KIDNEY; MALE; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); SEX CHARACTERISTICS; SP1 TRANSCRIPTION FACTOR; TATA BOX; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC;

EID: 0031596746     PISSN: 10522166     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Adler, A. J.; Danielsen, M.; Robins, D. M. Androgen-specific gene activation via a consensus glucocorticoid response element is determined by interaction with nonreceptor factors. Proc. Natl. Acad. Sci. USA 89:11660-11663; 1992.
2. Adler, A. J.; Scheller, A.; Hoffman, Y.; Robins, D. M. Multiple components of a complex androgen-dependent enhancer. Mol. Endocrinol. 5:1587-1596; 1991.
3. Beato, M. Regulation of gene expression by steroid hormones. In: Kahn, P., et al., eds. Oncogenes and growth control. New York: Springer-Verlag; 1986:219-225.
4. Blum, M.; Grant, D. M.; Demierre, A.; Meyer, U. A. N-acetylation pharmacogenetics: A gene deletion causes absence of arylamine N-acetyltransferase in liver of slow acetylator rabbits. Proc. Natl. Acad. Sci. USA 86:9554-9557; 1989.
5. Breathnach, R.; Chambon, P. Organization and expression of eucaryotic split genes coding for proteins. Annu. Rev. Biochem. 50:349-383; 1981.
6. Bucher, P. Weight matrix descriptions of four eukaryotic RNA polymerase II promoter elements derived from 502 unrelated promoter sequences. J. Mol. Biol. 212:563-578; 1990.
7. Corden, J.; Wasylyk, B.; Buchwalder, A.; Sassone-Corsi, P.; Kedinger, C.; Chambon, P. Promoter sequences of eukaryotic protein-coding genes. Science 209:1406-1414; 1980.
8. De Leon, J. H.; Martell, K. J.; Vatsis, K. P.; Weber, W. W. Slow acetylation in mice is caused by a labile and catalytically impaired mutant N-acetyltransferase (NAT2 9). Drug Metab. Dispos. 23:1354-1361; 1995.
9. Doll, M. A.; Hein, D. W. Cloning, sequencing and expression of NAT1 and NAT2 encoding genes from rapid and slow acetylator inbred rats. Pharmacogenetics 5:247-251; 1995.
10. Doll, M. A.; Jiang, W.; Deitz, A. C.; Rustan, T. D.; Hein, D. W. Identification of a novel allele at the human NAT1 acetyltransferase locus. Biochem. Biophys. Res. Commun. 233:584-591; 1997.
11. Estrada-Rodgers, L.; Levy, G. N.; Weber, W. W. Expression of arylamine N-acetyltransferase, NAT2, during development of CD1 mice. Pharmacologist 39:22; 1997.
12. Ferguson, R. J.; Doll, M. A.; Baumstark, B. R.; Hein, D. W. Polymorphic arylamine N-acetyltransferase encoding gene (NAT2) from homozygous rapid and slow acetylator congenic Syrian hamsters. Gene 140:247-249; 1994.
13. Ferguson, R. J.; Doll, M. A.; Rustan, T. D.; Baumstark, B. R.; Hein, D. W. Syrian hamster monomorphic N-acetyltransferase (NAT1) alleles: Amplification, cloning, sequencing, and expression in E. coli. Pharmacogenetics 4:82-90; 1994.
14. Jbilo, O.; Toutant, J. P.; Vatsis, K. P.; Chatonnet, A.; Lockridge, O. Promoter and transcription start site of human and rabbit butyrylcholinesterase genes. J. Biol. Chem. 269:20829-20837; 1994.
15. Kozak, M. Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs. Nucleic Acids Res. 12:857-872; 1984.
16. Latchman, D. S. Eukaryotic transcription factors. 2nd ed. San Diego: Academic Press Limited; 1995.
17. Lewin, B. Genes V. 5th ed. New York: Oxford University Press Inc.; 1994.
18. Martell, K. J.; Levy, G. N.; Weber, W. W. Cloned mouse N-acetyltransferases: Enzymatic properties of expressed Nat-1 and Nat-2 gene products. Mol. Pharmacol. 42:265-272; 1992.
19. Martell, K. J.; Vatsis, K. P.; Weber, W. W. Molecular genetic basis of rapid and slow acetylation in mice. Mol. Pharmacol. 40:218-227; 1991.
20. Menendez-Pelaez, A.; Marrufo, B.; Reiter, R. J.; Santana, C.; Guerrero, J. M. Testosterone increases N-acetyltransferase activity in both male and female Syrian hamster harderian glands. Biochem. Int. 19:115-121; 1989.
21. Nagata, K.; Özawa, S.; Miyata, M.; Shimada, M.; Yamazoe, Y.; Kato, R. Primary structure and molecular basis of polymorphic appearance of an acetyltransferase (AT-II)* in hamsters. Pharmacogenetics 4:91-100; 1994.
22. Prost, E.; Moore, D. D. CAT vectors for analysis of eukaryotic promoters and enhancers. Gene 45: 107-111; 1986.
23. Reeves, P. T.; Minchin, R. F.; Ilett, K. F. In vivo mechanisms for the enhanced acetylation of sulfamethazine in the rabbit after hydrocortisone treatment. J. Pharmacol. Exp. Ther. 248:348-352; 1989.
24. Robins, D. M.; Scheller, A.; Adler, A. J. Specific steroid response from a nonspecific DNA element. J. Steroid Biochem. Mol. Biol. 49:251-255; 1994.
25. Sasaki, Y.; Ohsako, S.; Deguchi, T. Molecular and genetic analyses of arylamine N-acetyltransferase polymorphism of rabbit liver. J. Biol. Chem. 266: 13243-13250; 1991.
26. Seed, B.; Sheen, J. Y. A simple phase-extraction assay for chloramphenicol acyltransferase activity. Gene 67:271-277; 1988.
27. Smolen, T. N.; Brewer, J. A.; Weber, W. W. Testosterone modulation of N-acetylation in mouse kidney. J. Pharmacol. Exp. Ther. 264:854-858; 1993.
28. Vatsis, K. P.; Weber, W. W. Structural heterogeneity of Caucasian N-acetyltransferase at the NAT1 gene locus. Arch. Biochem. Biophys. 301:71-76; 1993.
29. Vatsis, K. P.; Weber, W. W.; Bell, D. A.; Dupret, J. M.; Evans, D. A.; Grant, D. M.; Hein, D. W.; Lin, H. J.; Meyer, U. A.; Relling, M. V.; et al. Nomenclature for N-acetyltransferases. Pharmacogenetics 5:1-17; 1995.
30. Zaher, H.; Svensson, C. K. Glucocorticoid induction of hepatic acetyl CoA:arylamine N-acetyltransferase activity in the rat. Res. Commun. Chem. Pathol. Pharmacol. 83:195-208; 1994.