Diperoxovanadate alters endothelial cell focal contacts and barrier function: Role of tyrosine phosphorylation

Journal of Applied Physiology

Volumn 89, Issue 6, 2000, Pages 2333-2343

  Garcia, Joe G N ^a   Schaphorst, Kane L ^a   Verin, Alexander D ^a   Vepa, Suryanarayana ^a   Patterson, Carolyn E ^b   Natarajan, Viswanathan ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Division of Pulmonary and Critical Care Medicine   (United States)

Author keywords

Adherens junctions; Cadherin; Catenin; Electrical resistance

Indexed keywords

CADHERIN; DIPEROXOVANADATE; F ACTIN; FOCAL ADHESION KINASE; GENISTEIN; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROTEIN KINASE P60; PROTEIN TYROSINE KINASE ACTIVATOR; PROTEIN TYROSINE KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATTLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DOSE RESPONSE; ENDOTHELIUM CELL; ENZYME ACTIVATION; IMMUNOFLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

EID: 0033674779     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.2000.89.6.2333     Document Type: Article

References (53)

1. Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/β-catenin complex in cells transformed with a temperature-sensitive v-SRC gene
2. Peroxovanadium compounds: Biological actions and mechanism of insulin-mimesis
3. Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: A role in cytoskeletal assembly
4. Tyrosine phosphorylation and cadherin/catenin function
5. Intercellular adhesion molecule 1 activation induces tyrosine phosphorylation of the cytoskeleton-associated protein cortactin in brain microvessel endothelial cells
6. Induction of endothelial cell chemotaxis by sphingosine 1-phosphate and stabilization of endothelial monolayer barrier function by lysophosphatidic acid, potential mediators of hematopoietic angiogenesis
7. Calcium signaling in endothelial cells involves activation of tyrosine kinases and leads to activation of mitogen-activated protein kinases
8. Interdependence of calcium signaling and protein tyrosine phosphorylation in human endothelial cells
9. Mechanisms of ionomycin-induced endothelial permeability
10. Adherent neutrophils activate endothelial myosin light chain kinase: Role in transendothelial migration
11. Regulation of endothelial cell myosin light chain kinase by Rho, cortactin, and p60(src)
12. Regulation of endothelial cell gap formation and barrier dysfunction: Role of myosin light chain phosphorylation
13. Thrombin-induced increase in albumin permeability across the endothelium
14. A morphological biosensor for mammalian cells
15. Micromotion of mammalian cells measured electrically
16. Regulation of endothelial cell myosin light chain phosphorylation and permeability by vanadate
17. p60v-src causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system
18. 2 and vanadate stimulate protein tyrosine phosphorylation in intact cells
19. Protein tyrosine phosphorylation induced by lysophosphatidic acid in Rat-1 fibroblasts. Evidence that phosphorylation of map kinase is mediated by the Gi-p21ras pathway
20. Tyrosine phosphorylation and translocation of phospholipase C-γ2 in polymorphonuclear leukocytes treated with pervanadate
21. Role of calmodulin and myosin light-chain kinase in lung ischemia-reperfusion injury
22. Isometric contraction by fibroblasts and endothelial cells in tissue culture: A quantitative study
23. Pervanadate elicits proliferation and mediates activation of mitogen-activated protein (MAP) kinase in the nucleus
24. Lysophosphatidic acid induces tyrosine phosphorylation and activation of MAP-kinase and focal adhesion kinase in cultured Swiss 3T3 cells
25. Evolution of osmotic stress signaling via MAP kinase cascades
26. Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts
27. Regulation of lysophosphatidic acid-stimulated tyrosine phosphorylation of mitogen-activated protein kinase by protein kinase C- and pertussis toxin-dependent pathways in the endothelial cell line EAhy 926
28. Reactive oxygen species signaling through regulation of protein tyrosine phosphorylation in endothelial cells
29. Activation of endothelial cell phospholipase D by hydrogen peroxide and fatty acid hydroperoxide
30. Tyrosine kinases and calcium dependent activation of endothelial cell phospholipase D by diperoxovanadate
31. Evans blue dye as a marker of albumin clearance in cultured endothelial monolayer and isolated lung
32. Mechanisms of pertussis toxin-induced barrier dysfunction in bovine pulmonary artery endothelial monolayers
33. Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly
34. Activation of signal transduction in platelets by the tyrosine phosphatase inhibitor pervanadate (vanadyl hydroperoxide)
35. Peroxovanadate induces tyrosine phosphorylation of multiple signaling proteins in mouse liver and kidney
36. Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src
37. Thrombin-mediated focal adhesion plaque reorganization in endothelium: Role of protein phosphorylation
38. Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events
39. Lysophosphatidic acid stimulates tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130. Signaling pathways and cross-talk with platelet-derived growth factor
40. Multiple reactions in vanadyl-V(IV) oxidation by hydrogen peroxide
41. Role of tyrosine phosphorylation in thrombin-induced endothelial cell contraction and barrier function
42. Evidence that tyrosine phosphorylation may increase tight junction permeability
43. V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and β-catenin is not required for the shift
44. Activated neutrophils induce hyperpermeability and phosphorylation of adherens junction proteins in coronary venular endothelial cells
45. Electrical method for detection of endothelial cell shape change in real time: Assessment of endothelial barrier function
46. Stress-activated signalling pathways in yeast
47. Molecular linkage between cadherins and actin filaments in cell-cell adherens junctions
48. Tyrosine phosphorylation of the focal adhesion kinase pp125FAK during development: Relation to paxillin
49. Role of ras-dependent ERK activation in phorbol ester-induced endothelial cell barrier dysfunction
50. Regulation of endothelial cell gap formation and barrier function by myosin-associated phosphatase activities
51. Modulation of intercellular adherens-type junctions and tyrosine phosphorylation of their components in RSV-transformed cultured chick lens cells
52. Endothelial cell monolayer integrity. I. Characterization of dense peripheral band of microfilaments
53. Endothelial monolayer integrity. Perturbation of F-actin filaments and the dense peripheral bandvinculin network