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Volumn 21, Issue 17, 2000, Pages 3757-3764

Proteomics approach in classifying the biochemical basis of the anticancer activity of the new olomoucine-derived synthetic cyclin-dependent kinase inhibitor, bohemine

(8) Kovárová, Hana a,f Hajdúch, Marián b Koínková, Gabriela b Halada, Petr c Krupiková, Stanislava a Gouldsworthy, Adam d Zhelev, Nikolai e Strnad, Miroslav b

a Institute of Radiobiology and Immunology (Czech Republic)

b PALACKÝ UNIVERSITY (Czech Republic)

c INSTITUTE OF MATHEMATICS (Czech Republic)

d UNIVERSITY OF EDINBURGH (United Kingdom)

e CYCLACEL LTD (United Kingdom)

f Inst for Immunol and Radiobiology (Czech Republic)

Author keywords

Actin cytoskeleton; CEM T lymphoblastic leukemia; Cyclin dependent kinase inhibitor; Glycolysis; Mass spectrometry; Protein synthesis; Two dimensional polyacrylamide gel electrophoresis

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; CANCER CELLS; CELL CULTURE; CELLS; COMPUTATIONAL ELECTROMAGNETICS; DISEASES; ELECTROPHORESIS; ELECTROSPRAY IONIZATION; MOLECULAR BIOLOGY; MULTIVARIANT ANALYSIS; PATHOLOGY; PRINCIPAL COMPONENT ANALYSIS;

ACTIN CYTOSKELETON; CEM T-LYMPHOBLASTIC LEUKEMIA; CYCLIN-DEPENDENT KINASE INHIBITORS; GLYCOLYSIS; LYMPHOBLASTIC LEUKEMIA; OLOMOUCINE; PROTEIN SPOTS; PROTEIN SYNTHESIS; PROTEOMIC APPROACHES; TWO-DIMENSIONAL POLYACRYLAMIDE GEL ELECTROPHORESIS;

MASS SPECTROMETRY;

ACTIN; BOHEMINE; CYCLIN DEPENDENT KINASE INHIBITOR; ENOLASE; GUANOSINE DIPHOSPHATE; INITIATION FACTOR 5A; OLOMOUCINE; PROTEOME; RHO FACTOR; TRIOSEPHOSPHATE ISOMERASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CONTROLLED STUDY; CYTOSKELETON; GLYCOLYSIS; HUMAN; HUMAN CELL; LYMPHATIC LEUKEMIA; PRINCIPAL COMPONENT ANALYSIS; PROTEIN SYNTHESIS; T CELL LEUKEMIA; TANDEM MASS SPECTROMETRY;

EID: 0033673332 PISSN: 01730835 EISSN: None Source Type: Journal
DOI: 10.1002/1522-2683(200011)21:17<3757::AID-ELPS3757>3.0.CO;2-X Document Type: Article

Times cited : (52)

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