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Volumn 127, Issue 1, 1996, Pages 1-11

The L-arginine-nitric oxide pathway: Role in atherosclerosis and therapeutic implications

Author keywords

atherosclerosis; L arginine; nitrix oxide; therapeutic implications

Indexed keywords

ARGININE; NITRIC OXIDE;

EID: 0030588667     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(96)05953-9     Document Type: Review
Times cited : (164)

References (120)
  • 1
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • [1] Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980;288:373-376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 2
    • 0021287504 scopus 로고
    • The role of the endothelium in the responses of vascular smooth muscle to drugs
    • [2] Furchgott RF. The role of the endothelium in the responses of vascular smooth muscle to drugs. Annu Rev Pharmacol Toxicol 1984;24:175-197.
    • (1984) Annu Rev Pharmacol Toxicol , vol.24 , pp. 175-197
    • Furchgott, R.F.1
  • 3
    • 0023198721 scopus 로고
    • Nitric oxide accounts for the biological activity of endotheliun-derived relaxing factor
    • [3] Palmer RMJ, Ferrige AG, Moncada S. Nitric oxide accounts for the biological activity of endotheliun-derived relaxing factor. Nature 1987;327:524-526.
    • (1987) Nature , vol.327 , pp. 524-526
    • Palmer, R.M.J.1    Ferrige, A.G.2    Moncada, S.3
  • 4
    • 0023912670 scopus 로고
    • Vascular endothelial cells synthesize nitric oxide from L-arginine
    • [4] Palmer RMJ, Ashton DS, Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 1988;333:664-666.
    • (1988) Nature , vol.333 , pp. 664-666
    • Palmer, R.M.J.1    Ashton, D.S.2    Moncada, S.3
  • 5
    • 0027752805 scopus 로고
    • The L-arginine-nitric oxide pathway
    • [5] Moncada S, Higgs EA. The L-arginine-nitric oxide pathway. N Engl J Med 1993;329:2002-2012.
    • (1993) N Engl J Med , vol.329 , pp. 2002-2012
    • Moncada, S.1    Higgs, E.A.2
  • 6
    • 0025802065 scopus 로고
    • Cloned and expressed nitric oxide synthase structurally resembles cytochrom P-450 reductase
    • [6] Bredt DS, Hwang PM, Glatt CE, Lowenstein C, Reed RR, Snyder SH. Cloned and expressed nitric oxide synthase structurally resembles cytochrom P-450 reductase. Nature 1991;351:714-718.
    • (1991) Nature , vol.351 , pp. 714-718
    • Bredt, D.S.1    Hwang, P.M.2    Glatt, C.E.3    Lowenstein, C.4    Reed, R.R.5    Snyder, S.H.6
  • 7
    • 0025750850 scopus 로고
    • Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells
    • [7] Pollock JS, Förstermann U, Mitchell JA, Warner TD, Schmidt HHHW, Nakane M, Murad F. Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. Proc Natl Acad Sci USA 1991;88;10480-10484.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 10480-10484
    • Pollock, J.S.1    Förstermann, U.2    Mitchell, J.A.3    Warner, T.D.4    Schmidt, H.H.H.W.5    Nakane, M.6    Murad, F.7
  • 8
    • 0025011716 scopus 로고
    • Characterization of three inhibitors of endothelial nitrid oxide synthase in vitro and in vivo
    • [8] Rees DD, Palmer RMJ, Schulz R, Hodson HF, Moncada S. Characterization of three inhibitors of endothelial nitrid oxide synthase in vitro and in vivo. Br J Pharmacol 1990;101:746-752.
    • (1990) Br J Pharmacol , vol.101 , pp. 746-752
    • Rees, D.D.1    Palmer, R.M.J.2    Schulz, R.3    Hodson, H.F.4    Moncada, S.5
  • 9
    • 85047680312 scopus 로고
    • Long-term administration of L-arginine, L-NAME, and the exogenous NO donor molsidomine modulate urinary nitrate and cyclic GMP excretion in rats - Correlation with vascular reactivity
    • [9] Böger RH, Bode-Böger SM, Gerecke U, Frölich JC. Long-term administration of L-arginine, L-NAME, and the exogenous NO donor molsidomine modulate urinary nitrate and cyclic GMP excretion in rats - correlation with vascular reactivity. Cardiovasc Res 1994;28:494-499.
    • (1994) Cardiovasc Res , vol.28 , pp. 494-499
    • Böger, R.H.1    Bode-Böger, S.M.2    Gerecke, U.3    Frölich, J.C.4
  • 10
    • 0025848403 scopus 로고
    • Brain nitric oxide synthase is a biopterin- and flavin-containing multi-functional oxido-reductase
    • [10] Mayer B, John M, Heinzel B, Werner ER, Wachter H, Schultz G, Böhme E. Brain nitric oxide synthase is a biopterin- and flavin-containing multi-functional oxido-reductase. FEBS Lett 1991;288:187-191.
    • (1991) FEBS Lett , vol.288 , pp. 187-191
    • Mayer, B.1    John, M.2    Heinzel, B.3    Werner, E.R.4    Wachter, H.5    Schultz, G.6    Böhme, E.7
  • 11
    • 0025787205 scopus 로고
    • Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: An FAD- and FMN-containing flavoprotein
    • [11] Stuehr DJ, Cho HJ, Kwon NS, Weise MF, Nathan CF. Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein. Proc Natl Acad Sci USA 1991;88:7773-7778.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7773-7778
    • Stuehr, D.J.1    Cho, H.J.2    Kwon, N.S.3    Weise, M.F.4    Nathan, C.F.5
  • 12
    • 0028332056 scopus 로고
    • Nitric oxide synthase isoenzymes. Characterization, purification, molecular cloning, and functions
    • [12] Förstermann U, Closs EI, Pollock JS et al. Nitric oxide synthase isoenzymes. Characterization, purification, molecular cloning, and functions. Hypertension 1994;23:1121-1131.
    • (1994) Hypertension , vol.23 , pp. 1121-1131
    • Förstermann, U.1    Closs, E.I.2    Pollock, J.S.3
  • 14
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • [14] Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991;43:109-142.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.3
  • 15
    • 0025321355 scopus 로고
    • Biosynthesis and metabolism of endothelium-derived nitric oxide
    • [15] Ignarro LJ. Biosynthesis and metabolism of endothelium-derived nitric oxide. Annu Rev Pharmacol Toxicol 1990;30:535-560.
    • (1990) Annu Rev Pharmacol Toxicol , vol.30 , pp. 535-560
    • Ignarro, L.J.1
  • 16
    • 0027501213 scopus 로고
    • Metabolism and excretion of nitric oxide in humans. An experimental and clinical study
    • [16] Wennmalrn A, Benthin G, Edlund A et al. Metabolism and excretion of nitric oxide in humans. An experimental and clinical study. Circulation 1993;73:1121-1127.
    • (1993) Circulation , vol.73 , pp. 1121-1127
    • Wennmalrn, A.1    Benthin, G.2    Edlund, A.3
  • 17
    • 0025269712 scopus 로고
    • Role of endothelium-derived relaxing factor in regulation of renal hemodynamic responses
    • [17] Tolins JP, Palmer RMJ, Moncada S, Raij L. Role of endothelium-derived relaxing factor in regulation of renal hemodynamic responses. Am J Physiol 1990;27:H655-H662.
    • (1990) Am J Physiol , vol.27
    • Tolins, J.P.1    Palmer, R.M.J.2    Moncada, S.3    Raij, L.4
  • 19
    • 0026751343 scopus 로고
    • 3 excretion in the urine as an indicator of endothelium-derived relaxing factor during elevation of blood pressure
    • 3 excretion in the urine as an indicator of endothelium-derived relaxing factor during elevation of blood pressure. Clin Sci 1992;82:631-634.
    • (1992) Clin Sci , vol.82 , pp. 631-634
    • Suzuki, H.1    Ikenaga, H.2    Hishikawa, K.3    Nakaki, T.4    Kato, R.5    Saruta, T.6
  • 20
    • 0028106498 scopus 로고
    • L-arginine infusion decreases peripheral arterial resistance and inhibits platelet aggregation in healthy subjects
    • [20] Bode-Böger SM, Böger RH, Creutzig A et al. L-arginine infusion decreases peripheral arterial resistance and inhibits platelet aggregation in healthy subjects. Clin Sci 1994;87:303-310.
    • (1994) Clin Sci , vol.87 , pp. 303-310
    • Bode-Böger, S.M.1    Böger, R.H.2    Creutzig, A.3
  • 22
    • 0027936908 scopus 로고
    • Increased urinary nitrate excretion as an index of inflammatory activity in adjuvant arthritis
    • [22] Stichtenoth DO, Gutzki FM, Tsikas D et al. Increased urinary nitrate excretion as an index of inflammatory activity in adjuvant arthritis. Ann Rheum Dis 1994;53:547-549.
    • (1994) Ann Rheum Dis , vol.53 , pp. 547-549
    • Stichtenoth, D.O.1    Gutzki, F.M.2    Tsikas, D.3
  • 23
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
    • [23] Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 1990;87:1620-1624.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 24
    • 0027930057 scopus 로고
    • Evidence for nitric oxide-mediated oxidative damage in chronic inflammation
    • [24] Kaur H, Halliwell B. Evidence for nitric oxide-mediated oxidative damage in chronic inflammation. FEBS Lett 1994;350:9-12.
    • (1994) FEBS Lett , vol.350 , pp. 9-12
    • Kaur, H.1    Halliwell, B.2
  • 25
    • 0001599370 scopus 로고
    • Role of endothelium-derived nitric oxide in the regulation of blood pressure
    • [25] Rees DD, Palmer RMJ, Moncada S. Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc Natl Acad Sci USA 1989;86:3375-3378.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 3375-3378
    • Rees, D.D.1    Palmer, R.M.J.2    Moncada, S.3
  • 26
    • 0022590909 scopus 로고
    • Crucial role of endothelium in the vasodilator response to increased flow in vivo
    • [26] Pohl U, Holtz J, Busse R, Bassenge E. Crucial role of endothelium in the vasodilator response to increased flow in vivo. Hypertension 1986;8:37-44.
    • (1986) Hypertension , vol.8 , pp. 37-44
    • Pohl, U.1    Holtz, J.2    Busse, R.3    Bassenge, E.4
  • 27
    • 0025724919 scopus 로고
    • Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator
    • [27] Cooke JP, Rossitch E, Andon NA, Loscalzo J, Dzau VJ. Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator. J Clin Invest 1991;88:1663-1671.
    • (1991) J Clin Invest , vol.88 , pp. 1663-1671
    • Cooke, J.P.1    Rossitch, E.2    Andon, N.A.3    Loscalzo, J.4    Dzau, V.J.5
  • 28
    • 0000433631 scopus 로고
    • Periphere zirkulation
    • Siegenthaler W (ed), Stuttgart: Thieme
    • [28] Bollinger A. Periphere Zirkulation. In: Siegenthaler W (ed). Klinische Pathophysiologie. 5th edn, Stuttgart: Thieme 1982, pp. 756-794.
    • (1982) Klinische Pathophysiologie. 5th Edn , pp. 756-794
    • Bollinger, A.1
  • 29
    • 0002873515 scopus 로고
    • Blood flow regulation by adenosine in heart, brain, and skeletal muscle
    • Berne RM, Rail TW, Rubio R (eds). Boston: Martinus Nijhoff Publishing
    • [29] Berne RM, Winn HR, Knabb RM, Ely SW, Rubio R. Blood flow regulation by adenosine in heart, brain, and skeletal muscle. In: Berne RM, Rail TW, Rubio R (eds). Regulatory Function of Adenosine. Boston: Martinus Nijhoff Publishing, 1983. pp. 293-317.
    • (1983) Regulatory Function of Adenosine , pp. 293-317
    • Berne, R.M.1    Winn, H.R.2    Knabb, R.M.3    Ely, S.W.4    Rubio, R.5
  • 30
    • 0021019421 scopus 로고
    • Effect of different prostaglandin synthesis inhibitors on post-occlusive blood flow in human forearm
    • [30] Carlsson I, Wennmalm A. Effect of different prostaglandin synthesis inhibitors on post-occlusive blood flow in human forearm. Prostaglandins 1983;26:241-252.
    • (1983) Prostaglandins , vol.26 , pp. 241-252
    • Carlsson, I.1    Wennmalm, A.2
  • 33
    • 0027491127 scopus 로고
    • Chronic exercise enhances endothelium-mediated dilation of epicardial coronary arteries in conscious dogs
    • [33] Wang J, Wolin MS, Hintze TH. Chronic exercise enhances endothelium-mediated dilation of epicardial coronary arteries in conscious dogs. Circ Res 1993;73:829-838.
    • (1993) Circ Res , vol.73 , pp. 829-838
    • Wang, J.1    Wolin, M.S.2    Hintze, T.H.3
  • 36
    • 0028118896 scopus 로고
    • Chronic exercise in dogs increases coronary vascular endothelial nitric oxide production and endothelial cell nitric oxide synthase gene expression
    • [36] Sessa WC, Pritchard K, Seyedi N, Wang J, Hintze TH. Chronic exercise in dogs increases coronary vascular endothelial nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ Res 1994;74:349-353.
    • (1994) Circ Res , vol.74 , pp. 349-353
    • Sessa, W.C.1    Pritchard, K.2    Seyedi, N.3    Wang, J.4    Hintze, T.H.5
  • 37
    • 0023750135 scopus 로고
    • Response of human coronary arteries to aggregating platelets: Importance of endothelium-derived relaxing factor and prostanoids
    • [37] Förstermann U, Mügge A, Bode SM, Frölich JC. Response of human coronary arteries to aggregating platelets: importance of endothelium-derived relaxing factor and prostanoids. Circ Res 1988;63:306-312.
    • (1988) Circ Res , vol.63 , pp. 306-312
    • Förstermann, U.1    Mügge, A.2    Bode, S.M.3    Frölich, J.C.4
  • 38
    • 0023876496 scopus 로고
    • Selective attenuation of endothelium-mediated vasodilation in atherosclerotic human coronary arteries
    • [38] Förstermann U, Mügge A, Alheid U, Haverich A, Frölich JC. Selective attenuation of endothelium-mediated vasodilation in atherosclerotic human coronary arteries. Circ Res 1988;62:185-190.
    • (1988) Circ Res , vol.62 , pp. 185-190
    • Förstermann, U.1    Mügge, A.2    Alheid, U.3    Haverich, A.4    Frölich, J.C.5
  • 39
    • 0027409363 scopus 로고
    • Altered vascular responses to platelets from hypercholesterolemic humans
    • [39] Kaul S, Waack BJ, Padgeff RC, Brooks RM, Heistad DD. Altered vascular responses to platelets from hypercholesterolemic humans. Circ Res 1993;72:737-743.
    • (1993) Circ Res , vol.72 , pp. 737-743
    • Kaul, S.1    Waack, B.J.2    Padgeff, R.C.3    Brooks, R.M.4    Heistad, D.D.5
  • 40
    • 0024948682 scopus 로고
    • Mechanisms of abnormal endothelium-dependent vascular relaxation in atherosclerosis: Implications for altered autocrine and paracrine function of EDRF
    • [40] Guerra Rjr, Brotherton AFA, Goodwin PJ, Clark CR, Armstrong ML, Harrison DG. Mechanisms of abnormal endothelium-dependent vascular relaxation in atherosclerosis: implications for altered autocrine and paracrine function of EDRF. Blood Vessels 1989;26:300-314.
    • (1989) Blood Vessels , vol.26 , pp. 300-314
    • Guerra, R.1    Brotherton, A.F.A.2    Goodwin, P.J.3    Clark, C.R.4    Armstrong, M.L.5    Harrison, D.G.6
  • 41
    • 0025614563 scopus 로고
    • L-arginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits
    • [41] Girerd XJ, Hirsch AT, Cooke JP, Dzau VJ, Creager MA. L-arginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits. Circ Res 1990;67:1301-1308.
    • (1990) Circ Res , vol.67 , pp. 1301-1308
    • Girerd, X.J.1    Hirsch, A.T.2    Cooke, J.P.3    Dzau, V.J.4    Creager, M.A.5
  • 42
    • 0026020073 scopus 로고
    • Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta
    • [42] Cooke JP, Andon NA, Girerd XJ, Hirsch AT, Creager MA. Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta. Circulation 1991;83:1057-1062.
    • (1991) Circulation , vol.83 , pp. 1057-1062
    • Cooke, J.P.1    Andon, N.A.2    Girerd, X.J.3    Hirsch, A.T.4    Creager, M.A.5
  • 43
    • 0022654473 scopus 로고
    • Preservation of endothelium-dependent vascular relaxation in cholesterol-fed rabbit by treatment with the calcium blocker PN 200110
    • [43] Habib JB, Bossaller C, Wells S, Williams C, Morriseff JD, Henry PD. Preservation of endothelium-dependent vascular relaxation in cholesterol-fed rabbit by treatment with the calcium blocker PN 200110. Circ Res 1986;58:305-309.
    • (1986) Circ Res , vol.58 , pp. 305-309
    • Habib, J.B.1    Bossaller, C.2    Wells, S.3    Williams, C.4    Morriseff, J.D.5    Henry, P.D.6
  • 44
  • 45
    • 0024542681 scopus 로고
    • Lack of endothelium-dependent relaxation on coronary resistance arteries of cholesterol-fed rabbits
    • [45] Osborne JA, Siegman MJ, Sedar AW, Mooers SU, Lefer AM. Lack of endothelium-dependent relaxation on coronary resistance arteries of cholesterol-fed rabbits. Am J Physiol 1989;256:C591-C597.
    • (1989) Am J Physiol , vol.256
    • Osborne, J.A.1    Siegman, M.J.2    Sedar, A.W.3    Mooers, S.U.4    Lefer, A.M.5
  • 46
    • 0026338964 scopus 로고
    • Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine
    • [46] Drexler H, Zeiher AM, Meinzer K, Just H. Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine. Lancet 1991;338:1546-1550.
    • (1991) Lancet , vol.338 , pp. 1546-1550
    • Drexler, H.1    Zeiher, A.M.2    Meinzer, K.3    Just, H.4
  • 48
    • 0029037532 scopus 로고
    • Attenuation of acetylcholine-induced vasoconstriction by L-arginine is related to the progression of atherosclerosis
    • [48] Otsuji S, Nakajima O, Waku S et al. Attenuation of acetylcholine-induced vasoconstriction by L-arginine is related to the progression of atherosclerosis. Am Heart J 1995;129:1094-1100.
    • (1995) Am Heart J , vol.129 , pp. 1094-1100
    • Otsuji, S.1    Nakajima, O.2    Waku, S.3
  • 50
    • 0028939597 scopus 로고
    • Non-invasive detection on early endothelial dysfunction in hypercholesterolemic subjects
    • [50] Arcaro G, Zenere BM, Travia D et al. Non-invasive detection on early endothelial dysfunction in hypercholesterolemic subjects. Atherosclerosis 1995;114:247-254.
    • (1995) Atherosclerosis , vol.114 , pp. 247-254
    • Arcaro, G.1    Zenere, B.M.2    Travia, D.3
  • 51
    • 0004916124 scopus 로고
    • Endothelium-derived relaxing factor reduces platelet adhesion to bovine endothelial cells
    • [51] Sneddon JM, Vane JR. Endothelium-derived relaxing factor reduces platelet adhesion to bovine endothelial cells. Proc Natl Acad Sci USA 1988;85:2800-2804.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 2800-2804
    • Sneddon, J.M.1    Vane, J.R.2
  • 52
    • 0024312198 scopus 로고
    • Endothelium-derived relaxing factor(s) and coronary vasospasm
    • [52] Vanhouffe PM, Shirnokawa H. Endothelium-derived relaxing factor(s) and coronary vasospasm. Circulation 1989;80:1-9.
    • (1989) Circulation , vol.80 , pp. 1-9
    • Vanhouffe, P.M.1    Shirnokawa, H.2
  • 53
    • 0025731835 scopus 로고
    • Nitric oxide:An endogenous modulator of leukocyte adhesion
    • [53] Kubes P, Suzuki M, Ganger DN. Nitric oxide:an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA 1991;88:4651-4655.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4651-4655
    • Kubes, P.1    Suzuki, M.2    Ganger, D.N.3
  • 54
    • 0027262461 scopus 로고
    • Decreased basal nitric oxide release in hypercholesterolemia increases neutrophil adherence to rabbit coronary artery endothelium
    • [54] Lefer AM, Ma XI. Decreased basal nitric oxide release in hypercholesterolemia increases neutrophil adherence to rabbit coronary artery endothelium. Arterioscler Thromb 1993;13:771-776.
    • (1993) Arterioscler Thromb , vol.13 , pp. 771-776
    • Lefer, A.M.1    Ma, X.I.2
  • 55
    • 0028293434 scopus 로고
    • Enhanced endothelial adhesiveness in hypercholesterolemia is attenuated by L-arginine
    • [55] Tsao PS, McEvoy LM, Drexler H, Butcher EC, Cooke JP. Enhanced endothelial adhesiveness in hypercholesterolemia is attenuated by L-arginine. Circulation 1994;89:2176-2182.
    • (1994) Circulation , vol.89 , pp. 2176-2182
    • Tsao, P.S.1    McEvoy, L.M.2    Drexler, H.3    Butcher, E.C.4    Cooke, J.P.5
  • 56
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis:A perspective for the 1990s
    • [56] Ross R. The pathogenesis of atherosclerosis:a perspective for the 1990s. Nature 1993;362:801-809.
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 57
    • 0019946645 scopus 로고
    • Increased leukocyte oxidative metabolism in hyperlipoprotemaemia
    • [57] Ludwig PW, Hunninghake DB, Hoidal JR. Increased leukocyte oxidative metabolism in hyperlipoprotemaemia. Lancet 1982;ii:348-350.
    • (1982) Lancet , vol.2 , pp. 348-350
    • Ludwig, P.W.1    Hunninghake, D.B.2    Hoidal, J.R.3
  • 58
    • 0028650305 scopus 로고
    • Vascular release of superoxide radicals is enhanced in hypercholesterolemic rabbits
    • [58] Mügge A, Brandes R, Böger RH et al. Vascular release of superoxide radicals is enhanced in hypercholesterolemic rabbits. J Cardiovasc Pharmacol 1994;24:994-998.
    • (1994) J Cardiovasc Pharmacol , vol.24 , pp. 994-998
    • Mügge, A.1    Brandes, R.2    Böger, R.H.3
  • 59
    • 0023828745 scopus 로고
    • Role of superoxide in endothelial-cell modification of low-density lipoproteins
    • [59] Steinbrecher UP. Role of superoxide in endothelial-cell modification of low-density lipoproteins. Biochem Biophys Acta 1988;959:20-30.
    • (1988) Biochem Biophys Acta , vol.959 , pp. 20-30
    • Steinbrecher, U.P.1
  • 60
    • 0028289443 scopus 로고
    • A definition of initial, fatty streak, and intermediate lesions of atherosclerosis
    • [60] Stary HC, Chandler AB, Glagow S et al. A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. Circulation 1994;89:2462-2478.
    • (1994) Circulation , vol.89 , pp. 2462-2478
    • Stary, H.C.1    Chandler, A.B.2    Glagow, S.3
  • 61
    • 0026725537 scopus 로고
    • Cytokine regulation of endothelial cells function
    • [61] Mantovani A, Bussolino F, Dejana E. Cytokine regulation of endothelial cells function. FASEB J 1992;6:2591-2599.
    • (1992) FASEB J , vol.6 , pp. 2591-2599
    • Mantovani, A.1    Bussolino, F.2    Dejana, E.3
  • 62
    • 0027740243 scopus 로고
    • Human atherosclerosis. Immunocytochemical analysis of cell activation and proliferation in lesions of young adults
    • [62] Katsuda S, Coltrera MD, Ross R, Gown AM. Human atherosclerosis. Immunocytochemical analysis of cell activation and proliferation in lesions of young adults. Am J Pathol 1993;142:1787-1793.
    • (1993) Am J Pathol , vol.142 , pp. 1787-1793
    • Katsuda, S.1    Coltrera, M.D.2    Ross, R.3    Gown, A.M.4
  • 63
    • 0026630603 scopus 로고
    • Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase
    • [63] Clancy RM, Leszczynska-Piziak J, Abramson SB. Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase. J Clin Invest 1992;90:1116-1121.
    • (1992) J Clin Invest , vol.90 , pp. 1116-1121
    • Clancy, R.M.1    Leszczynska-Piziak, J.2    Abramson, S.B.3
  • 64
    • 0024553336 scopus 로고
    • Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells
    • [64] Garg UC, Hassid A. Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest 1989;83:1774-1777.
    • (1989) J Clin Invest , vol.83 , pp. 1774-1777
    • Garg, U.C.1    Hassid, A.2
  • 65
    • 0025204692 scopus 로고
    • Inhibition by nitric oxide and nitric oxide-producing vasodilators of DNA synthesis in vascular smooth muscle cells
    • [65] Nakaki T, Nakayama M, Kato R. Inhibition by nitric oxide and nitric oxide-producing vasodilators of DNA synthesis in vascular smooth muscle cells. Eur J Pharmacol 1990;189:347-353.
    • (1990) Eur J Pharmacol , vol.189 , pp. 347-353
    • Nakaki, T.1    Nakayama, M.2    Kato, R.3
  • 66
    • 0025169393 scopus 로고
    • Low basal and stimulated release of nitric oxide in atherosclerotic epicardial coronary arteries
    • [66] Chester AH, O'Neil GS, Moncada S, Tadjkarimi S, Yacoub MH. Low basal and stimulated release of nitric oxide in atherosclerotic epicardial coronary arteries. Lancet 1990;336:897-900.
    • (1990) Lancet , vol.336 , pp. 897-900
    • Chester, A.H.1    O'Neil, G.S.2    Moncada, S.3    Tadjkarimi, S.4    Yacoub, M.H.5
  • 67
    • 0025677318 scopus 로고
    • Diet-induced atherosclerosis increases the release of nitrogen oxides from rabbit aorta
    • [67] Minor RL, Myers PR, Guerra R, Bates JN, Harrison DG. Diet-induced atherosclerosis increases the release of nitrogen oxides from rabbit aorta. J Clin Invest 1990;86:2109-2116.
    • (1990) J Clin Invest , vol.86 , pp. 2109-2116
    • Minor, R.L.1    Myers, P.R.2    Guerra, R.3    Bates, J.N.4    Harrison, D.G.5
  • 68
    • 0029124027 scopus 로고
    • Supplementation of hypercholesterolaemic rabbits with L-arginine reduces the vascular release of superoxide anions and restores NO production
    • [68] Böger RH, Bode-Böger SM, Mügge A et al. Supplementation of hypercholesterolaemic rabbits with L-arginine reduces the vascular release of superoxide anions and restores NO production. Atherosclerosis 1995;117:273-284.
    • (1995) Atherosclerosis , vol.117 , pp. 273-284
    • Böger, R.H.1    Bode-Böger, S.M.2    Mügge, A.3
  • 69
    • 0027309122 scopus 로고
    • Characterization of L-arginine transport by pulmonary artery endothelial cells
    • [69] Greene B, Pacitti AJ, Souba WW. Characterization of L-arginine transport by pulmonary artery endothelial cells. Am J Physiol 1993;264:L351-L356.
    • (1993) Am J Physiol , vol.264
    • Greene, B.1    Pacitti, A.J.2    Souba, W.W.3
  • 70
    • 0028219077 scopus 로고
    • Increase of an endogenous inhibitor of nitric oxide synthesis in serum of high cholesterol fed rabbits
    • [70] Yu X, Li Y, Xiong Y. Increase of an endogenous inhibitor of nitric oxide synthesis in serum of high cholesterol fed rabbits. Life Sci 1994;54:753-758.
    • (1994) Life Sci , vol.54 , pp. 753-758
    • Yu, X.1    Li, Y.2    Xiong, Y.3
  • 72
    • 0028821643 scopus 로고
    • Oxidized low-densitiy lipoprotein decreases the expression of endothelial nitric oxide synthase
    • [72] Liao JK, Shin WS, Lee WY, Clark SL. Oxidized low-densitiy lipoprotein decreases the expression of endothelial nitric oxide synthase. J Biol Chem 1995;270:319-324.
    • (1995) J Biol Chem , vol.270 , pp. 319-324
    • Liao, J.K.1    Shin, W.S.2    Lee, W.Y.3    Clark, S.L.4
  • 73
    • 0027242030 scopus 로고
    • Hypercholesterolemia increases endothelial superoxide anion production
    • [73] Ohara Y, Peterson TE, Harrison DG. Hypercholesterolemia increases endothelial superoxide anion production. J Clin Invest 1993;91:2546-2551.
    • (1993) J Clin Invest , vol.91 , pp. 2546-2551
    • Ohara, Y.1    Peterson, T.E.2    Harrison, D.G.3
  • 74
    • 0027481965 scopus 로고
    • The reaction of NO with superoxide
    • [74] Huie RE, Padmaja S. The reaction of NO with superoxide. Free Radical Res Comms 1993;18:195-199.
    • (1993) Free Radical Res Comms , vol.18 , pp. 195-199
    • Huie, R.E.1    Padmaja, S.2
  • 75
    • 0028373681 scopus 로고
    • Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry
    • [75] Beckmann JS, Ye YZ, Anderson PG et al. Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry. Biol Chem Hoppe-Seyler 1994;375:81-88.
    • (1994) Biol Chem Hoppe-Seyler , vol.375 , pp. 81-88
    • Beckmann, J.S.1    Ye, Y.Z.2    Anderson, P.G.3
  • 76
    • 0023873792 scopus 로고
    • Lipid peroxidation and endothelial cell injury:Implications in atherosclerosis
    • [76] Henning B, Chow CK. Lipid peroxidation and endothelial cell injury:implications in atherosclerosis. Free Radical Biol Med 1988;4:99-106.
    • (1988) Free Radical Biol Med , vol.4 , pp. 99-106
    • Henning, B.1    Chow, C.K.2
  • 77
    • 0022545164 scopus 로고
    • Superoxide anion release by human endothelial cells: Synergism between a phorbol ester and a calcium ionophore
    • [77] Matsubara T, Ziff M. Superoxide anion release by human endothelial cells: synergism between a phorbol ester and a calcium ionophore. J Cell Physiol 1986;127:207-210.
    • (1986) J Cell Physiol , vol.127 , pp. 207-210
    • Matsubara, T.1    Ziff, M.2
  • 78
    • 0028304674 scopus 로고
    • Intracellular oxidative stress induced by nitric oxide synthesis inhibition increases endothelial cell adhesion to neutrophils
    • [78] Niu XF, Smith CW, Kubes P. Intracellular oxidative stress induced by nitric oxide synthesis inhibition increases endothelial cell adhesion to neutrophils. Circ Res 1994;74:1133-1140.
    • (1994) Circ Res , vol.74 , pp. 1133-1140
    • Niu, X.F.1    Smith, C.W.2    Kubes, P.3
  • 79
    • 0029133481 scopus 로고
    • Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion
    • [79] Pritchard KA, Groszek L, Smalley DM et al. Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion. Circ Res 1995;77:510-518.
    • (1995) Circ Res , vol.77 , pp. 510-518
    • Pritchard, K.A.1    Groszek, L.2    Smalley, D.M.3
  • 80
    • 0026333959 scopus 로고
    • Role of oxidized low density lipoprotein in atherogenesis
    • [80] Witzurn JL, Steinberg D. Role of oxidized low density lipoprotein in atherogenesis. J Clin Invest 1991;88:1785-1792.
    • (1991) J Clin Invest , vol.88 , pp. 1785-1792
    • Witzurn, J.L.1    Steinberg, D.2
  • 81
    • 0025358714 scopus 로고
    • Oxidized low-density lipoproteins cause contraction and inhibit endothelium-dependent relaxation in the pig coronary artery
    • [81] Simon BC, Cunningham LD, Cohen RA. Oxidized low-density lipoproteins cause contraction and inhibit endothelium-dependent relaxation in the pig coronary artery. J Clin Invest 1990;86:75-79.
    • (1990) J Clin Invest , vol.86 , pp. 75-79
    • Simon, B.C.1    Cunningham, L.D.2    Cohen, R.A.3
  • 82
    • 0026518550 scopus 로고
    • Oxidative modification of low-density lipoproteins and the inhibition of relaxations mediated by endothelium-derived nitric oxide in rabbit aorta
    • [82] Plane F, Bruckdorfer KR, Kerr P, Steuer A, Jacobs M. Oxidative modification of low-density lipoproteins and the inhibition of relaxations mediated by endothelium-derived nitric oxide in rabbit aorta. Br J Pharmacol 1992;105:216-222.
    • (1992) Br J Pharmacol , vol.105 , pp. 216-222
    • Plane, F.1    Bruckdorfer, K.R.2    Kerr, P.3    Steuer, A.4    Jacobs, M.5
  • 83
    • 0028898258 scopus 로고
    • Modulation of oxidized low-density lipoprotein-induced microvascular dysfunction by nitric oxide
    • [83] Liao L, Granger DN. Modulation of oxidized low-density lipoprotein-induced microvascular dysfunction by nitric oxide. Am J Physiol 1995;268:H1643-H1650.
    • (1995) Am J Physiol , vol.268
    • Liao, L.1    Granger, D.N.2
  • 84
    • 0027193894 scopus 로고
    • Endothelial nuclear factor-KB and the initiation of the atherosclerotic lesion
    • [84] Collins T. Endothelial nuclear factor-KB and the initiation of the atherosclerotic lesion. Lab Invest 1993;5:499-508.
    • (1993) Lab Invest , vol.5 , pp. 499-508
    • Collins, T.1
  • 85
    • 0028169447 scopus 로고
    • NF-KB and Sp1 regulate transcription of the human monocyte chemoattractant protein-1 gene
    • [85] Ueda A, Okuda K, Ohno S et al. NF-KB and Sp1 regulate transcription of the human monocyte chemoattractant protein-1 gene. J Immunol 1994;153:2052-2063.
    • (1994) J Immunol , vol.153 , pp. 2052-2063
    • Ueda, A.1    Okuda, K.2    Ohno, S.3
  • 86
    • 0027365599 scopus 로고
    • Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells
    • [86] Marui N, Offerman MK, Swerlick R et al. Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. J Clin Invest 1993;92:1866-1874.
    • (1993) J Clin Invest , vol.92 , pp. 1866-1874
    • Marui, N.1    Offerman, M.K.2    Swerlick, R.3
  • 87
    • 0028035106 scopus 로고
    • The high-output nitric oxide pathway: Role and regulation
    • [87] Xie Q, Nathan C. The high-output nitric oxide pathway: role and regulation. J Leukocyte Biol 1994;56:576-582.
    • (1994) J Leukocyte Biol , vol.56 , pp. 576-582
    • Xie, Q.1    Nathan, C.2
  • 88
    • 0011281095 scopus 로고
    • NO modulates monocyte chemoattractant protein-1 in human endothelial cells: Implications for the pathogenesis of atherosclerosis
    • Abstract
    • [88] Zeiher AM, Schray-Utz B, Busse R. NO modulates monocyte chemoattractant protein-1 in human endothelial cells: implications for the pathogenesis of atherosclerosis. Circulation 1993;88(Suppl): 1-367, (Abstract).
    • (1993) Circulation , vol.88 , Issue.SUPPL. , pp. 1-367
    • Zeiher, A.M.1    Schray-Utz, B.2    Busse, R.3
  • 89
    • 0023119509 scopus 로고
    • Impaired muscarinic endothelium-dependent relaxation and cyclic guanosine 5′-monophosphate formation in atherosclerotic human coronary artery and rabbit aorta
    • [89] Bossaller C, Habib GB, Yamamoto H, Williams C, Wells S, Henry PD. Impaired muscarinic endothelium-dependent relaxation and cyclic guanosine 5′-monophosphate formation in atherosclerotic human coronary artery and rabbit aorta. J Clin Invest 1987;79:170-174.
    • (1987) J Clin Invest , vol.79 , pp. 170-174
    • Bossaller, C.1    Habib, G.B.2    Yamamoto, H.3    Williams, C.4    Wells, S.5    Henry, P.D.6
  • 90
    • 0026058284 scopus 로고
    • Loss of endothelial pertussis toxin-sensitive G-protein function in atherosclerotic porcine coronary arteries
    • [90] Shimokawa H, Flavahan NA, Vanhoutte PM. Loss of endothelial pertussis toxin-sensitive G-protein function in atherosclerotic porcine coronary arteries. Circulation 1991;83:652-660.
    • (1991) Circulation , vol.83 , pp. 652-660
    • Shimokawa, H.1    Flavahan, N.A.2    Vanhoutte, P.M.3
  • 91
    • 0028872213 scopus 로고
    • Impaired endothelium-dependent vascular relaxation in patients with hypercholesterolemia extends beyond the muscarinic receptor
    • [91] Casino PR, Kilcoyne CM, Cannon RO, Quyyumi AA, Panza JA. Impaired endothelium-dependent vascular relaxation in patients with hypercholesterolemia extends beyond the muscarinic receptor. Am J Cardiol 1995;75:40-44.
    • (1995) Am J Cardiol , vol.75 , pp. 40-44
    • Casino, P.R.1    Kilcoyne, C.M.2    Cannon, R.O.3    Quyyumi, A.A.4    Panza, J.A.5
  • 93
    • 0027172930 scopus 로고
    • Endothelium-derived nitric oxide, endothelin, and platelet vessel wall interaction: Alterations in hypercholesterolemia and atherosclerosis
    • [93] Tanner FC, Boulanger CM, Lüscher TF. Endothelium-derived nitric oxide, endothelin, and platelet vessel wall interaction: alterations in hypercholesterolemia and atherosclerosis. Semin Thromb Hemost 1993;19:167-175.
    • (1993) Semin Thromb Hemost , vol.19 , pp. 167-175
    • Tanner, F.C.1    Boulanger, C.M.2    Lüscher, T.F.3
  • 94
    • 23444436348 scopus 로고
    • Role of supoeroxide unions in the mediation of endothelium-dependent contractions
    • [94] Cosentino F, Sill JC, Katusic ZS. Role of supoeroxide unions in the mediation of endothelium-dependent contractions. Hypertension 1994;23:229-235.
    • (1994) Hypertension , vol.23 , pp. 229-235
    • Cosentino, F.1    Sill, J.C.2    Katusic, Z.S.3
  • 96
    • 0028818593 scopus 로고
    • Novel guanylyl cyclase inhibitor, ODQ reveals role of nitric oxide, but not of cyclic GMP in endothelin-1 secretion
    • [96] Brunner F, Stessel H, Kukovetz WR. Novel guanylyl cyclase inhibitor, ODQ reveals role of nitric oxide, but not of cyclic GMP in endothelin-1 secretion. FEBS Lett 1995;376:262-266.
    • (1995) FEBS Lett , vol.376 , pp. 262-266
    • Brunner, F.1    Stessel, H.2    Kukovetz, W.R.3
  • 97
    • 0027299798 scopus 로고
    • Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells
    • [97] Hirata Y, Emori T, Eguchi S et al. Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells. J Clin Invest 1993;91:1367-1373.
    • (1993) J Clin Invest , vol.91 , pp. 1367-1373
    • Hirata, Y.1    Emori, T.2    Eguchi, S.3
  • 98
    • 0023483253 scopus 로고
    • Restoration of endothelium-dependent relaxation by dietary treatment of atherosclerosis
    • [98] Harrison DG, Armstrong ML, Freiman PC, Heistad DD. Restoration of endothelium-dependent relaxation by dietary treatment of atherosclerosis. J Clin Invest 1987;80:1808-1811.
    • (1987) J Clin Invest , vol.80 , pp. 1808-1811
    • Harrison, D.G.1    Armstrong, M.L.2    Freiman, P.C.3    Heistad, D.D.4
  • 99
    • 0024504128 scopus 로고
    • Cardiovascular effects of acute hypercholesterolemia in rabbits. Reversal with lovastatin treatment
    • [99] Osborne JA, Lento PH, Siegfried MR, Stahl GL, Fusman B, Lefer AM. Cardiovascular effects of acute hypercholesterolemia in rabbits. Reversal with lovastatin treatment. J Clin Invest 1989;83:465-473.
    • (1989) J Clin Invest , vol.83 , pp. 465-473
    • Osborne, J.A.1    Lento, P.H.2    Siegfried, M.R.3    Stahl, G.L.4    Fusman, B.5    Lefer, A.M.6
  • 103
    • 0028361033 scopus 로고
    • L-arginine improves endothelium-dependent vasorelaxation and reduces intimal hyperplasia after balloon angioplasty
    • [103] Tarry WC, Makhoul RG. L-arginine improves endothelium-dependent vasorelaxation and reduces intimal hyperplasia after balloon angioplasty. Arterioscler Thromb 1994;14:938-943.
    • (1994) Arterioscler Thromb , vol.14 , pp. 938-943
    • Tarry, W.C.1    Makhoul, R.G.2
  • 104
    • 0028945283 scopus 로고
    • Discordant effects of dietary L-arginine on vascular structure and reactivity in hypercholesterolemic rabbits
    • [104] Singer AH, Tsao PS, Wang BY, Bloch DA, Cooke JP. Discordant effects of dietary L-arginine on vascular structure and reactivity in hypercholesterolemic rabbits. J Cardiovasc Pharmacol 1995;25:710-716.
    • (1995) J Cardiovasc Pharmacol , vol.25 , pp. 710-716
    • Singer, A.H.1    Tsao, P.S.2    Wang, B.Y.3    Bloch, D.A.4    Cooke, J.P.5
  • 105
    • 0026774371 scopus 로고
    • L-arginine infusion induces hypotension and diuresis/natriuresis concomitant with increased urinary excretion of nitrite/nitrate and cyclic GMP in humans
    • [105] Kanno K, Hirata Y, Emori T et al. L-arginine infusion induces hypotension and diuresis/natriuresis concomitant with increased urinary excretion of nitrite/nitrate and cyclic GMP in humans. Clin Exp Pharmacol Physiol 1992;19:619-625.
    • (1992) Clin Exp Pharmacol Physiol , vol.19 , pp. 619-625
    • Kanno, K.1    Hirata, Y.2    Emori, T.3
  • 106
    • 0030027672 scopus 로고    scopus 로고
    • L-arginine induces nitric oxide-dependent vasodilation in patients with critical limb ischemia. A randomized, controlled study
    • [106] Bode-Böger SM, Böger RH, Alfke H et al. L-arginine induces nitric oxide-dependent vasodilation in patients with critical limb ischemia. A randomized, controlled study. Circulation 1996;93:85-90.
    • (1996) Circulation , vol.93 , pp. 85-90
    • Bode-Böger, S.M.1    Böger, R.H.2    Alfke, H.3
  • 107
    • 0026644644 scopus 로고
    • Effects of L-arginine on forearm vessels and responses to acetylcholine
    • [107] Imaizumi T, Hiooka Y, Masaki H et al. Effects of L-arginine on forearm vessels and responses to acetylcholine. Hypertension 1992;20:511-517.
    • (1992) Hypertension , vol.20 , pp. 511-517
    • Imaizumi, T.1    Hiooka, Y.2    Masaki, H.3
  • 108
    • 0028273052 scopus 로고
    • Investigation of decreased availability of nitric oxide precursor as the mechanism responsible for impaired endothelium-dependent vasodilation in hypercholesterolemic patients
    • [108] Casino PR, Kilcoyne CM, Quyyumi AA, Hoeg JM, Panza JA. Investigation of decreased availability of nitric oxide precursor as the mechanism responsible for impaired endothelium-dependent vasodilation in hypercholesterolemic patients. J Am Coll Cardiol 1994;23:844-850.
    • (1994) J Am Coll Cardiol , vol.23 , pp. 844-850
    • Casino, P.R.1    Kilcoyne, C.M.2    Quyyumi, A.A.3    Hoeg, J.M.4    Panza, J.A.5
  • 109
    • 0026662348 scopus 로고
    • Comparison of the release of vasoactive factors from venous and arterial bovine cultured endothelial cells
    • [109] D'Orleans-Juste P, Mitchell JA, Wood EG, Hecker M, Vane JR. Comparison of the release of vasoactive factors from venous and arterial bovine cultured endothelial cells. Can J Physiol Pharmacol 1992;70:687-694.
    • (1992) Can J Physiol Pharmacol , vol.70 , pp. 687-694
    • D'Orleans-Juste, P.1    Mitchell, J.A.2    Wood, E.G.3    Hecker, M.4    Vane, J.R.5
  • 110
    • 0029670349 scopus 로고    scopus 로고
    • Elevated L-arginine/dimethylarginine ratio contributes to enhanced systemic NO production by dietary L-arginine in hypercholesterolemic rabbits
    • [110] Bode-Böger SM, Böger RH, Kienke S, Junker W, Frölich JC. Elevated L-arginine/dimethylarginine ratio contributes to enhanced systemic NO production by dietary L-arginine in hypercholesterolemic rabbits. Biochem Biophys Res Commun 1996;219:598-603.
    • (1996) Biochem Biophys Res Commun , vol.219 , pp. 598-603
    • Bode-Böger, S.M.1    Böger, R.H.2    Kienke, S.3    Junker, W.4    Frölich, J.C.5
  • 111
    • 0026095472 scopus 로고
    • Dilator actions of arginine in human peripheral vasculature
    • [111] Calver A, Collier J, Valiance P. Dilator actions of arginine in human peripheral vasculature. Clin Sci 1991;81:695-700.
    • (1991) Clin Sci , vol.81 , pp. 695-700
    • Calver, A.1    Collier, J.2    Valiance, P.3
  • 112
    • 0029086629 scopus 로고
    • Vascular and hormonal responses to arginine: Provision of substrate for nitric oxide or non-specific effect?
    • [112] MacAllister RJ, Calver AL, Collier J et al. Vascular and hormonal responses to arginine: provision of substrate for nitric oxide or non-specific effect? Clin Sci 1995;89:183-190.
    • (1995) Clin Sci , vol.89 , pp. 183-190
    • MacAllister, R.J.1    Calver, A.L.2    Collier, J.3
  • 113
    • 0028991325 scopus 로고
    • Pressor, renal and endocrine effects of L-arginine in essential hypertensives
    • [113] Pedrinelli R, Ebel M, Catapano G et al. Pressor, renal and endocrine effects of L-arginine in essential hypertensives. Eur J Clin Pharmacol 1995;48:195-201.
    • (1995) Eur J Clin Pharmacol , vol.48 , pp. 195-201
    • Pedrinelli, R.1    Ebel, M.2    Catapano, G.3
  • 114
  • 115
    • 0028172446 scopus 로고
    • L-arginine-induced hypotension in the rat: Evidence that NO synthesis is not involved
    • [115] Jun T, Wennmalm A. L-arginine-induced hypotension in the rat: evidence that NO synthesis is not involved. Acta Physiol Scand 1994;152:385-390.
    • (1994) Acta Physiol Scand , vol.152 , pp. 385-390
    • Jun, T.1    Wennmalm, A.2
  • 116
    • 0026609864 scopus 로고
    • G-Methyl-L-arginine, an inhibitor of L-arginine-derived nitric oxide synthesis, stimulates renal sympathetic nerve activity in vivo
    • G-Methyl-L-arginine, an inhibitor of L-arginine-derived nitric oxide synthesis, stimulates renal sympathetic nerve activity in vivo. Circ Res 1992;70:607-611.
    • (1992) Circ Res , vol.70 , pp. 607-611
    • Sakuma, I.1    Togashi, H.2    Yoshioka, M.3
  • 117
    • 0025131570 scopus 로고
    • Characterization of the L-arginine: Nitric oxide pathway in human platelets
    • [117] Radomski MW, Palmer RMJ, Moncada S. Characterization of the L-arginine: nitric oxide pathway in human platelets. Br J Pharmacol 1990;101:325-328.
    • (1990) Br J Pharmacol , vol.101 , pp. 325-328
    • Radomski, M.W.1    Palmer, R.M.J.2    Moncada, S.3
  • 118
    • 0026736734 scopus 로고
    • EDRF plays central role in collateral flow after arterial occlusion in rabbit ear
    • [118] Randall MD, Grifith TM. EDRF plays central role in collateral flow after arterial occlusion in rabbit ear. Am J Physiol 1992;263:H752-H760.
    • (1992) Am J Physiol , vol.263
    • Randall, M.D.1    Grifith, T.M.2
  • 119
    • 0028343337 scopus 로고
    • L-arginine reverses the impairment of nitric oxide-dependent collateral perfusion in dietary-induced hypercholesterolemia in the rabbit
    • [119] Randall MD, Ujiie H, Griffith TM. L-arginine reverses the impairment of nitric oxide-dependent collateral perfusion in dietary-induced hypercholesterolemia in the rabbit. Clin Sci 1994;87:53-59.
    • (1994) Clin Sci , vol.87 , pp. 53-59
    • Randall, M.D.1    Ujiie, H.2    Griffith, T.M.3
  • 120
    • 0027527402 scopus 로고
    • Inhibition of low-density lipoprotein oxidation by nitric oxide. Potential role in atherogenesis
    • [120] Hogg N, Kalyanaraman B, Joseph J, Struck A, Parthasarathy S. Inhibition of low-density lipoprotein oxidation by nitric oxide. Potential role in atherogenesis. FEBS Lett 1993;334:170-174.
    • (1993) FEBS Lett , vol.334 , pp. 170-174
    • Hogg, N.1    Kalyanaraman, B.2    Joseph, J.3    Struck, A.4    Parthasarathy, S.5


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