Selective abolishment of pyrimidine nucleoside kinase activity of herpes simplex virus type 1 thymidine kinase by mutation of alanine-167 to tyrosine

Molecular Pharmacology

Volumn 58, Issue 6, 2000, Pages 1326-1332

  Degrève, Bart ^a   Esnouf, Robert ^b   De Clercq, Erik ^a   Balzarini, Jan ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

5 (2 BROMOVINYL) 2' DEOXYURIDINE; ACICLOVIR; ALANINE; BUCICLOVIR; GANCICLOVIR; LOBUCAVIR; NUCLEOSIDE ANALOG; PENCICLOVIR; PHOSPHOTRANSFERASE; PURINE NUCLEOSIDE DERIVATIVE; PYRIMIDINE NUCLEOSIDE; TYROSINE;

AMINO ACID SUBSTITUTION; CYTOSTASIS; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; HERPES SIMPLEX VIRUS 1; MOLECULAR RECOGNITION; NONHUMAN; OSTEOSARCOMA CELL; PRIORITY JOURNAL; SHORT SURVEY;

EID: 0033664250     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.58.6.1326     Document Type: Short Survey

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