The Tetrahymena p80/p95 complex is required for proper telomere length maintenance and micronuclear genome stability

Molecular Cell

Volumn 6, Issue 4, 2000, Pages 827-837

  Miller, Michael C ^a   Collins, Kathleen ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PROTOZOAL PROTEIN; RNA; TELOMERASE;

ARTICLE; CHROMOSOME ANALYSIS; DNA PROTEIN COMPLEX; ENZYME ACTIVITY; ENZYME PURIFICATION; GENE EXPRESSION; GENETIC STABILITY; MICRONUCLEUS; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; PROTEIN DNA INTERACTION; REVERSE TRANSCRIPTION; RNA TRANSPORT; TELOMERE; TETRAHYMENA;

TETRAHYMENA;

EID: 0033638401     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(05)00078-X     Document Type: Article

References (24)

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5. Purification of Tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme
6. Genome downsizing during ciliate development: Nuclear division of labor through chromosome restructuring
7. Interactin of recombinant Tetrahymena telomerase proteins p80 and p95 with telomerase RNA and telomeric DNA substrates
8. Specific RNA residue interactions required for enzymatic functions of Tetrahymena telomerase
9. A mammalian telomerase-associated protein
10. Human telomerase contains evolutionary conserved catalytic and structural subunits
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12. An unusual sequence arrangement in the telomeres of the germ-line micronucleus in Tetrahymena thermophila
13. Block in anaphase chromosome separation caused by a telomerase template mutation
14. Dynamics of telomere length variation in Tetrahymena thermophila
15. Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes
16. Three ever shorter telomere (EST) genes are dispensable for in vitro yeast telomerase activity
17. A mutant with a defect in telomere elongation leads to senescence in yeast
18. A telomerase component is defective in the human disease dyskeratosis congenita
19. TLP1: A gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family
20. Excision of micronuclear-specific DNA requires parental expression of pdd2p and occurs independently from DNA replication in Tetrahymena thermophila
21. Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle
22. Developmentally programmed healing of chromosomes by telomerase in Tetrahymena
23. In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs
24. Telomeres: Beginning to understand the end