Substrate inhibition of nitric oxide synthase in pulmonary artery endothelial cells in culture

Nitric Oxide - Biology and Chemistry

Volumn 1, Issue 6, 1997, Pages 469-475

  Su, Yunchao ^a   Couch, Margaret ^b   Block, Edward R ^a,b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

AMINO ACID COMPOSITION; ANIMAL CELL; ARTERY ENDOTHELIUM; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; SWINE;

EID: 0031417917     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1006/niox.1997.0151     Document Type: Article

References (19)

1. Moncada S., Palmer R. M. J., Higgs E. A. Nitric oxide: Physiology, pathology, and pharmacology. Pharmacol. Rev. 43:1991;109-142.
2. Palmer R. M. J., Ashton D. S., Moncada S. Vascular endothelial cells synthesize nitric oxide fromL. Nature. 333:1988;664-666.
3. Xie Q.-W., Cho H. J., Calaycay J., Mumford R. A., Swiderek K. M., Lee T. D., Ding A., Troso T., Nathan C. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science. 256:1992;225-228.
4. Moncada S., Higgs E. A. Molecular mechanisms and therapeutic strategies related to nitric oxide. FASEB J. 9:1995;1319-1330.
5. Pollock J. S., Förstermann U., Mitchell J. A., Warner T. D., Schmidt H. H. H. W., Nakane M., Murad F. Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. Proc. Natl. Acad. Sci. USA. 88:1991;10480-10484.
6. Cook J. P., Singer A. H., Tsao P., Zera P., Rowan B. A., Billingham M. E. Antiatherogenic effect ofL. J. Clin. Invest. 90:1992;1168-1172.
7. Reyes A. A., Karl I. E., Klahr S. Role of arginine in health and in renal disease. Am. J. Physiol. 267:1994;F331-F346.
8. Block E. R., Patel J. M., Edwards D. A. Mechanism of hypoxic injury to pulmonary artery endothelial cell plasma membranes. Am. J. Physiol. 257:1989;C223-C231.
9. Misko T. P., Schilling R. J., Salvemini D., Moore W. M., Currie M. G. A fluorometric assay for measurement of nitrite in biological samples. Anal. Biochem. 214:1993;11-16.
10. Patel J. M., Zhang J., Block E. R. Nitric oxide-induced inhibition of lung endothelial cell nitric oxide synthase via interaction with allosteric thiols: Role of thioredoxin in regulation of catalytic activity. Am. J. Respir. Cell. Mol. Biol. 15:1996;410-419.
11. Su Y., Block E. R. Acute hypoxia increases intracellularL. J. Cell. Physiol. 167:1996;349-353.
12. Richards M. K., Marletta M. A. Characterization of neuronal nitric oxide synthase and a C415H mutant, purified from a baculovirus overexpression system. Biochemistry. 33:1994;14723-14732.
13. Barbul A. Arginine: Biochemistry, physiology, and therapeutic implications. JPEN. 10:1996;227-238.
14. Koifman B., Wollman Y., Bogomolny N., Chernichowsky T., Finkelstein A., Peer G., Scherez J., Blum M., Laniado S., Iaina A., Keren G. Improvement of cardiac performance by intravenous infusion ofL. J. Am. Coll. Cardiol. 26:1995;1251-1256.
15. Bode-Böger S. M., Böger R. H., Alfke H., Heinzel D., Tsikas D., Creutzig A., Alexander K., Frölich J. C. L. Circulation. 93:1996;85-90.
16. Chauhan A., More R. S., Mullins P. A., Taylor G., Peth M., Schofield P. M. Aging-associated endothelial dysfunction in humans is reversed byL. J. Am. Coll. Cardiol. 28:1996;1796-1804.
17. Hirooka Y., Imaizumi T., Tagawa T., Shiramoto M., Endo T., Ando S.-I., Takeshita A. Effects ofL. Circulation. 90:1994;658-668.
18. Kanno K., Hirata Y., Emori T. L. Clin. Exp. Pharmacol. Physiol. 19:1992;619-625.
19. Fukaya Y., Ohhashi T. Acetylcholine- and flow-induced production and release of nitric oxide in arterial and venous endothelial cells. Am. J. Physiol. 270:1996;H99-H106.