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Volumn 54, Issue 2, 2000, Pages 269-274

Molecular mechanism of monamine toxicity in Parkinson's disease: Hypothetical cell death model

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE; METAL ION; MONOAMINE; BIOGENIC AMINE; METAL;

EID: 0033625739     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1054/mehy.1999.0839     Document Type: Article
Times cited : (9)

References (79)
  • 1
    • 0027358350 scopus 로고
    • Worldwide occurrence of parkinson's disease: An updated review
    • Zhang Z.-X., Roman G. C. Worldwide occurrence of parkinson's disease: an updated review. Neuroepidemiology. 12:1993;195-208.
    • (1993) Neuroepidemiology , vol.12 , pp. 195-208
    • Zhang, Z.-X.1    Roman, G.C.2
  • 2
    • 84935983539 scopus 로고
    • An assay on the shaking palsy. London (1817) Reproduced
    • M. Critchley. London: Macmillan
    • Parkinson J. An assay on the shaking palsy. London (1817) Reproduced. Critchley M. James Parkinson. 1955;Macmillan, London.
    • (1955) James Parkinson
    • Parkinson, J.1
  • 3
    • 0029981526 scopus 로고    scopus 로고
    • Neuropathology of Parkinson's disease
    • Forno L. Neuropathology of Parkinson's disease. J Neuropath Exp Neurol. 55:1996;259-272.
    • (1996) J Neuropath Exp Neurol , vol.55 , pp. 259-272
    • Forno, L.1
  • 5
    • 0027396368 scopus 로고
    • Dominantly inhereted early onset parkinsonism: Neuropathology of a new form
    • Dwork A. I., Balmaceda A., Fazzini E. A. Dominantly inhereted early onset parkinsonism: neuropathology of a new form. Neurology. 43:1993;69-74.
    • (1993) Neurology , vol.43 , pp. 69-74
    • Dwork, A.I.1    Balmaceda, A.2    Fazzini, E.A.3
  • 6
    • 0028198309 scopus 로고
    • Familial juvenile parkinsonism: Clinical and pathologic study in a family
    • Takahashi H., Ohama M. D., Suzuki S. Familial juvenile parkinsonism: clinical and pathologic study in a family. Neurology. 44:1994;437-441.
    • (1994) Neurology , vol.44 , pp. 437-441
    • Takahashi, H.1    Ohama, M.D.2    Suzuki, S.3
  • 7
    • 0028828141 scopus 로고
    • A clinical and genetic study of familial cases of Parkinson's disease
    • Plante-Bordeneuve V., Taussing D., Thomas F. A clinical and genetic study of familial cases of Parkinson's disease. J Neurol Sci. 133:1995;164-172.
    • (1995) J Neurol Sci , vol.133 , pp. 164-172
    • Plante-Bordeneuve, V.1    Taussing, D.2    Thomas, F.3
  • 8
    • 0026548217 scopus 로고
    • Quantitation of a mithocondrial deletion in parkinson's disease
    • Mann V. M., Cooper J. M., Schapira A. H. V. Quantitation of a mithocondrial deletion in parkinson's disease. Fed Eur Biochem Soc. 299:1992;218-222.
    • (1992) Fed Eur Biochem Soc , vol.299 , pp. 218-222
    • Mann, V.M.1    Cooper, J.M.2    Schapira, A.H.V.3
  • 9
    • 0026340039 scopus 로고
    • Is Parkinson's disease a mitochondrial disorder?
    • Nakagawa-Hattori Y., Yoshino H., Kondo T. Is Parkinson's disease a mitochondrial disorder? J Neurol Sci. 107:1992;29-33.
    • (1992) J Neurol Sci , vol.107 , pp. 29-33
    • Nakagawa-Hattori, Y.1    Yoshino, H.2    Kondo, T.3
  • 10
    • 0030012558 scopus 로고    scopus 로고
    • Possible environmental, occupational and other etiologic factors for parkinson's disease: A case-control study in Germany
    • Seidler A., Hellenbrand W., Robra B. P. Possible environmental, occupational and other etiologic factors for parkinson's disease: a case-control study in Germany. Neurology. 46:1996;1275-1284.
    • (1996) Neurology , vol.46 , pp. 1275-1284
    • Seidler, A.1    Hellenbrand, W.2    Robra, B.P.3
  • 11
    • 0027944855 scopus 로고
    • Metals and free radicals in neurodegeneration
    • Olanow C., Arendash G. Metals and free radicals in neurodegeneration. Curr Opin Neurol. 7:1994;548-558.
    • (1994) Curr Opin Neurol , vol.7 , pp. 548-558
    • Olanow, C.1    Arendash, G.2
  • 12
    • 0022369108 scopus 로고
    • Catecholamine metabolism: Basic aspects and clinical significance
    • Kopin I. J. Catecholamine metabolism: Basic aspects and clinical significance. Pharm Rev. 37:1985;333-386.
    • (1985) Pharm Rev , vol.37 , pp. 333-386
    • Kopin, I.J.1
  • 13
    • 0026484388 scopus 로고
    • The oxidant stress Hypothesis in Parkinson's disease: Evidence supporting it
    • Fanh S., Cohen G. The oxidant stress Hypothesis in Parkinson's disease: evidence supporting it. Ann Neurol. 32:1992;804-812.
    • (1992) Ann Neurol , vol.32 , pp. 804-812
    • Fanh, S.1    Cohen, G.2
  • 14
    • 0026514643 scopus 로고
    • What process causes nigral cell death in Parkinson's disease?
    • Jenner P. What process causes nigral cell death in Parkinson's disease? Neurol Clin. 10:1992;387-403.
    • (1992) Neurol Clin , vol.10 , pp. 387-403
    • Jenner, P.1
  • 15
    • 0030001780 scopus 로고    scopus 로고
    • Oxidative stress and antioxidant therapy in parkinson's disease
    • Ebadi M., Srinivasan S. K., Baxi M. Oxidative stress and antioxidant therapy in parkinson's disease. Prog Neurol. 48:1996;1-19.
    • (1996) Prog Neurol , vol.48 , pp. 1-19
    • Ebadi, M.1    Srinivasan, S.K.2    Baxi, M.3
  • 16
    • 0031899172 scopus 로고    scopus 로고
    • Oxidative mechanism in nigral cell death in Parkinson's disease
    • Jenner P. Oxidative mechanism in nigral cell death in Parkinson's disease. Mov Disord. 13:1998;24-34.
    • (1998) Mov Disord , vol.13 , pp. 24-34
    • Jenner, P.1
  • 17
    • 0000870364 scopus 로고
    • Oxygen is poisonous-an introduction to oxygen toxicity and free radicals
    • B. Halliwell, & J. M. C. Gutteridge. Oxford: Clarendon Press
    • Halliwell B., Gutteridge J. M. C. Oxygen is poisonous-an introduction to oxygen toxicity and free radicals. Halliwell B., Gutteridge J. M. C. Free Radicals in Biology and Medicine. 1989;1-20 Clarendon Press, Oxford.
    • (1989) Free Radicals in Biology and Medicine , pp. 1-20
    • Halliwell, B.1    Gutteridge, J.M.C.2
  • 18
    • 0029751104 scopus 로고    scopus 로고
    • Oxidative stress and the pathogenesis of parkinson's disease
    • Jenner P., Olanow C. W. Oxidative stress and the pathogenesis of parkinson's disease. Neurology. 47:1996;S161-S170.
    • (1996) Neurology , vol.47
    • Jenner, P.1    Olanow, C.W.2
  • 20
    • 0018095085 scopus 로고
    • Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones
    • Graham D. G. Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones. Mol Pharmacol. 14:1978;633-643.
    • (1978) Mol Pharmacol , vol.14 , pp. 633-643
    • Graham, D.G.1
  • 21
    • 0024465355 scopus 로고
    • Redox and addition chemistry of quinoid compounds and its implications
    • Brunmark A., Cadenas E. Redox and addition chemistry of quinoid compounds and its implications. Free Rad Biol Med. 7:1989;435-477.
    • (1989) Free Rad Biol Med , vol.7 , pp. 435-477
    • Brunmark, A.1    Cadenas, E.2
  • 22
    • 0027348681 scopus 로고
    • Iron and ferritin in substantia nigra in Parkinson's disease
    • Jellinger K. A., Kienzl E., Rumpelmaier G. Iron and ferritin in substantia nigra in Parkinson's disease. Adv Neurol. 60:1993;267-272.
    • (1993) Adv Neurol , vol.60 , pp. 267-272
    • Jellinger, K.A.1    Kienzl, E.2    Rumpelmaier, G.3
  • 23
    • 0029432331 scopus 로고
    • The role of transition metals in the pathogenesis of Parkinson's disease
    • Kienzl E., Puchinger L., Jellinger K. The role of transition metals in the pathogenesis of Parkinson's disease. J Neurol Sci. 134:1995;69-78.
    • (1995) J Neurol Sci , vol.134 , pp. 69-78
    • Kienzl, E.1    Puchinger, L.2    Jellinger, K.3
  • 24
    • 0031947244 scopus 로고    scopus 로고
    • Iron metabolism and Parkinson's disease
    • Hirsh E. C., Faucheux B. A. Iron metabolism and Parkinson's disease. Mov Disord. 13:1998;39-45.
    • (1998) Mov Disord , vol.13 , pp. 39-45
    • Hirsh, E.C.1    Faucheux, B.A.2
  • 25
    • 0026666528 scopus 로고
    • Iron-melanin complex in substantia nigra of Parkinsonian brain: An X-ray microanalysis
    • Jellinger K., Kienzl E., Rumpelmaier G. Iron-melanin complex in substantia nigra of Parkinsonian brain: an X-ray microanalysis. J Neurochem. 59:1992;1168-1171.
    • (1992) J Neurochem , vol.59 , pp. 1168-1171
    • Jellinger, K.1    Kienzl, E.2    Rumpelmaier, G.3
  • 26
    • 4243607831 scopus 로고
    • Toxicity of iron and hydrogen peroxide: The Fenton reaction
    • Winterbourn C. C. Toxicity of iron and hydrogen peroxide: the Fenton reaction. Toxicol Lett. 82/83:1995;969-974.
    • (1995) Toxicol Lett , vol.8283 , pp. 969-974
    • Winterbourn, C.C.1
  • 27
    • 0025126555 scopus 로고
    • Role of free radicals and catalytic metal ions in human disease-an overview
    • Halliwell B., Guterridge J. M. C. Role of free radicals and catalytic metal ions in human disease-an overview. Meth Enzymol. 186:1990;1-85.
    • (1990) Meth Enzymol , vol.186 , pp. 1-85
    • Halliwell, B.1    Guterridge, J.M.C.2
  • 29
    • 0026061854 scopus 로고
    • Dopa and dopamine cause cultured neuronal death in presence of iron
    • Tanaka M., Sotomatsu A., Kanai H., Hirai S. Dopa and dopamine cause cultured neuronal death in presence of iron. J Neurol Sci. 101:1991;198-203.
    • (1991) J Neurol Sci , vol.101 , pp. 198-203
    • Tanaka, M.1    Sotomatsu, A.2    Kanai, H.3    Hirai, S.4
  • 30
    • 0025821265 scopus 로고
    • Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative disease affecting the basal ganglia
    • Dexter D. T., Carayon A., Javoy-Agid F. Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative disease affecting the basal ganglia. Brain. 114:1991;1953-1975.
    • (1991) Brain , vol.114 , pp. 1953-1975
    • Dexter, D.T.1    Carayon, A.2    Javoy-Agid, F.3
  • 31
    • 0030940439 scopus 로고    scopus 로고
    • Occupational exposures to metals as risk factors for Parkinson's disease
    • Gorell J. M., Johnson C. C., Rybicki B. A. Occupational exposures to metals as risk factors for Parkinson's disease. Neurology. 48:1997;650-658.
    • (1997) Neurology , vol.48 , pp. 650-658
    • Gorell, J.M.1    Johnson, C.C.2    Rybicki, B.A.3
  • 32
    • 0023261328 scopus 로고
    • Manganese poisoning and the attack of trivalent manganese upon catecholamines
    • Archibald F. S., Tyree C. Manganese poisoning and the attack of trivalent manganese upon catecholamines. Arch Biochem Biophys. 256:1987;638-650.
    • (1987) Arch Biochem Biophys , vol.256 , pp. 638-650
    • Archibald, F.S.1    Tyree, C.2
  • 33
    • 0029073693 scopus 로고
    • Covalent crosslinking of neurofilament protein by oxidized catechols as a potential mechanism of Lewy body formation
    • Montine T. J., Farris D. B., Graham D. G. Covalent crosslinking of neurofilament protein by oxidized catechols as a potential mechanism of Lewy body formation. J Neuropathol Exp Neurol. 54:1995;311-319.
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 311-319
    • Montine, T.J.1    Farris, D.B.2    Graham, D.G.3
  • 34
    • 0029065908 scopus 로고
    • Manganese and copper promote the binding of dopamine to 'serotonin binding proteins' in bovine frontal cortex
    • Velez Pardo C., Jimenez Del Rio M., Ebinger G., Vauquelin G. Manganese and copper promote the binding of dopamine to 'serotonin binding proteins' in bovine frontal cortex. Neurochem Int. 26:1995;615-622.
    • (1995) Neurochem Int , vol.26 , pp. 615-622
    • Velez Pardo, C.1    Jimenez Del Rio, M.2    Ebinger, G.3    Vauquelin, G.4
  • 35
    • 0000341879 scopus 로고
    • Free radicals, oxidative stress, and neurodegeneration
    • D. B. Calne. Philadelphia: W.B., Saunders
    • Cohen G., Werner P. Free radicals, oxidative stress, and neurodegeneration. Calne D. B. Neurodegenerative Diseases. 1994;139-162 W.B., Saunders, Philadelphia.
    • (1994) Neurodegenerative Diseases , pp. 139-162
    • Cohen, G.1    Werner, P.2
  • 36
    • 0029414750 scopus 로고    scopus 로고
    • Chemical evidence for 6-hydroxydopamine to be an endogenous toxic factor in the pathogenesis of Parkinson's disease
    • Jellinger K., Linert L., Kienzl E. Chemical evidence for 6-hydroxydopamine to be an endogenous toxic factor in the pathogenesis of Parkinson's disease. J Neural Transm. 46:1997;297-314.
    • (1997) J Neural Transm , vol.46 , pp. 297-314
    • Jellinger, K.1    Linert, L.2    Kienzl, E.3
  • 37
    • 0030790785 scopus 로고    scopus 로고
    • Iron-mediated generation of the neurotoxin 6-hydroxydopamine quinone by reaction of fatty acid hydroperoxides with dopamine: A possible contributory mechanism for neuronal degeneration in parkinson's disease
    • Pezzella A., D'ischia M., Napolitano A., Misuraca G., Prota G. Iron-mediated generation of the neurotoxin 6-hydroxydopamine quinone by reaction of fatty acid hydroperoxides with dopamine: a possible contributory mechanism for neuronal degeneration in parkinson's disease. J Med Chem. 40:1997;2211-2216.
    • (1997) J Med Chem , vol.40 , pp. 2211-2216
    • Pezzella, A.1    D'Ischia, M.2    Napolitano, A.3    Misuraca, G.4    Prota, G.5
  • 38
    • 0026324174 scopus 로고
    • Ascorbic acid enhances the effect of 6-hydroxydopamine and H2O2 on iron dependent DNA strand breaks and related processes in the neuroblastoma cell line SK-N-SH
    • Bruchelt G., Schraufsetatter I. U., Niethammer D., Cochrane C. G. Ascorbic acid enhances the effect of 6-hydroxydopamine and H2O2 on iron dependent DNA strand breaks and related processes in the neuroblastoma cell line SK-N-SH. Cancer Res. 51:1991;6066-6072.
    • (1991) Cancer Res , vol.51 , pp. 6066-6072
    • Bruchelt, G.1    Schraufsetatter, I.U.2    Niethammer, D.3    Cochrane, C.G.4
  • 39
    • 0026662216 scopus 로고
    • Biochemical and toxicological properties of the oxidation products of catecholamines
    • Bindoli A., Rogobello M. P., Deeble D. J. Biochemical and toxicological properties of the oxidation products of catecholamines. Free Rad Biol Med. 13:1992;391-405.
    • (1992) Free Rad Biol Med , vol.13 , pp. 391-405
    • Bindoli, A.1    Rogobello, M.P.2    Deeble, D.J.3
  • 40
    • 0028940012 scopus 로고
    • Strand scission in DNA induced by L-DOPA in the presence of Cu(II)
    • Husain S., Hadi S. M. Strand scission in DNA induced by L-DOPA in the presence of Cu(II). FEBS Lett. 364:1995;75-78.
    • (1995) FEBS Lett , vol.364 , pp. 75-78
    • Husain, S.1    Hadi, S.M.2
  • 41
    • 0027479977 scopus 로고
    • Apoptosis: The biochemistry and molecular biology of programmed cell death
    • Schwartzman R. A., Cidlowski J. A. Apoptosis: the biochemistry and molecular biology of programmed cell death. Endocrine Rev. 14:1993;133-151.
    • (1993) Endocrine Rev , vol.14 , pp. 133-151
    • Schwartzman, R.A.1    Cidlowski, J.A.2
  • 42
    • 0028929328 scopus 로고
    • Mechanisms of genes and cellular suicide
    • Steller H. Mechanisms of genes and cellular suicide. Science. 267:1995;1445-1449.
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 43
    • 0026058318 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim R. W. Cell death during development of the nervous system. Annu Rev Neurosci. 14:1991;453-501.
    • (1991) Annu Rev Neurosci , vol.14 , pp. 453-501
    • Oppenheim, R.W.1
  • 44
    • 0031898760 scopus 로고    scopus 로고
    • Programmed cell death and Parkinson's disease
    • Burke R. E. Programmed cell death and Parkinson's disease. Mov Disord. 13:1998;17-23.
    • (1998) Mov Disord , vol.13 , pp. 17-23
    • Burke, R.E.1
  • 45
    • 0027138785 scopus 로고
    • Detection of the initial stages of DNA fragmentation in apoptosis
    • Walker P. R., Kokileva LeBlanc L., Sikorska J. Detection of the initial stages of DNA fragmentation in apoptosis. Bio Techniques. 15:1993;1032-1036.
    • (1993) Bio Techniques , vol.15 , pp. 1032-1036
    • Walker, P.R.1    Kokileva Leblanc, L.2    Sikorska, J.3
  • 46
    • 0031013141 scopus 로고    scopus 로고
    • Apoptotic-like changes in Lewy-body-associated disorders and normal aging in substantia nigral neurons
    • Tompkins M. M., Basgeall E. J., Zamrini E., Hill W. D. Apoptotic-like changes in Lewy-body-associated disorders and normal aging in substantia nigral neurons. Am J Pathol. 150:1997;119-131.
    • (1997) Am J Pathol , vol.150 , pp. 119-131
    • Tompkins, M.M.1    Basgeall, E.J.2    Zamrini, E.3    Hill, W.D.4
  • 47
    • 0025063462 scopus 로고
    • Toxicity of 6-hydroxydopamine and dopamine for dopaminergic neurons in culture
    • Michel P. P., Hefti F. Toxicity of 6-hydroxydopamine and dopamine for dopaminergic neurons in culture. J Neurosci Res. 26:1990;428-435.
    • (1990) J Neurosci Res , vol.26 , pp. 428-435
    • Michel, P.P.1    Hefti, F.2
  • 48
    • 0025824668 scopus 로고
    • Intranigral iron injection induces behavioral and biochemical 'Parkinsonism' in rats
    • Ben-Shachar D., Youdim M. B. H. Intranigral iron injection induces behavioral and biochemical 'Parkinsonism' in rats. J Neurochem. 57:1991;2133-2135.
    • (1991) J Neurochem , vol.57 , pp. 2133-2135
    • Ben-Shachar, D.1    Youdim, M.B.H.2
  • 50
    • 0027362832 scopus 로고
    • Toxic and protective effects of L-DOPA on mesencephalic cell cultures
    • Mytilineou C., Han S. H., Cohen G. Toxic and protective effects of L-DOPA on mesencephalic cell cultures. J Neurochem. 61:1993;1470-1478.
    • (1993) J Neurochem , vol.61 , pp. 1470-1478
    • Mytilineou, C.1    Han, S.H.2    Cohen, G.3
  • 51
    • 0029969350 scopus 로고    scopus 로고
    • Nature of inhibition of mitochondrial respiratory complex I by 6-hydroxydopamine
    • Glinka Y., Tipton K. F., Youdim M. B. H. Nature of inhibition of mitochondrial respiratory complex I by 6-hydroxydopamine. J Neurochem. 66:1996;2004-2010.
    • (1996) J Neurochem , vol.66 , pp. 2004-2010
    • Glinka, Y.1    Tipton, K.F.2    Youdim, M.B.H.3
  • 52
    • 0029970954 scopus 로고    scopus 로고
    • 6-hydroxydopamine induces thymocyte apoptosis in mice
    • Tsao C.-W., Cheng J.-T., Shen C.-L., Lin Y.-S. 6-hydroxydopamine induces thymocyte apoptosis in mice. J Neuroimm. 65:1996;91-95.
    • (1996) J Neuroimm , vol.65 , pp. 91-95
    • Tsao, C.-W.1    Cheng, J.-T.2    Shen, C.-L.3    Lin, Y.-S.4
  • 53
    • 0345704610 scopus 로고
    • Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
    • Green L. A., Tischler A. S. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci. 73:1976;2424-2428.
    • (1976) Proc Natl Acad Sci , vol.73 , pp. 2424-2428
    • Green, L.A.1    Tischler, A.S.2
  • 54
    • 0032125654 scopus 로고    scopus 로고
    • Monoamine and iron-related toxicity: From 'serotonin binding proteins' to lipid peroxidation and apoptosis in PC12 cells
    • Velez Pardo C., Jimenez Del Rio M., Ebinger G., Vauquelin G. Monoamine and iron-related toxicity: from 'serotonin binding proteins' to lipid peroxidation and apoptosis in PC12 cells. Gen Pharmacol. 31:1998;19-24.
    • (1998) Gen Pharmacol , vol.31 , pp. 19-24
    • Velez Pardo, C.1    Jimenez Del Rio, M.2    Ebinger, G.3    Vauquelin, G.4
  • 55
    • 0023251916 scopus 로고
    • Neurotoxins, Parkinsonism and Parkinson's disease
    • Langston J. W., Irwin I., Ricaurte G. A. Neurotoxins, Parkinsonism and Parkinson's disease. Pharmacol Ther. 32:1987;19-49.
    • (1987) Pharmacol Ther , vol.32 , pp. 19-49
    • Langston, J.W.1    Irwin, I.2    Ricaurte, G.A.3
  • 56
    • 0025972738 scopus 로고
    • DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems
    • Halliwell B., Aruoma O. I. DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems. FEBS Lett. 281:1991;9-19.
    • (1991) FEBS Lett , vol.281 , pp. 9-19
    • Halliwell, B.1    Aruoma, O.I.2
  • 57
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • Halliwell B. Reactive oxygen species and the central nervous system. J Neurochem. 59:1992;1609-1623.
    • (1992) J Neurochem , vol.59 , pp. 1609-1623
    • Halliwell, B.1
  • 58
    • 0028127058 scopus 로고
    • Neurotoxin-induced cell death in neuronal PC12 cells is mediated by induction of apoptosis
    • Walkinshaw G., Waters C. M. Neurotoxin-induced cell death in neuronal PC12 cells is mediated by induction of apoptosis. Neurosci. 63:1994;975-987.
    • (1994) Neurosci , vol.63 , pp. 975-987
    • Walkinshaw, G.1    Waters, C.M.2
  • 59
    • 0029051317 scopus 로고
    • Induction of apoptosis in catecholaminergic PC12 cells by L-DOPA. Implication for the treatment of Parkinson's disease
    • Walkinshaw G., Waters C. M. Induction of apoptosis in catecholaminergic PC12 cells by L-DOPA. Implication for the treatment of Parkinson's disease. J Clin Inv. 95:1995;2458-2464.
    • (1995) J Clin Inv , vol.95 , pp. 2458-2464
    • Walkinshaw, G.1    Waters, C.M.2
  • 61
    • 0032488992 scopus 로고    scopus 로고
    • Dopamnie induces apoptosis through an oxidation-involved SAPk/ JNK activation pathway
    • Luo Y., Umegaki H., Wang X., Abe R., Roth G. S. Dopamnie induces apoptosis through an oxidation-involved SAPk/ JNK activation pathway. J Biol Chem. 273:1998;3756-3764.
    • (1998) J Biol Chem , vol.273 , pp. 3756-3764
    • Luo, Y.1    Umegaki, H.2    Wang, X.3    Abe, R.4    Roth, G.S.5
  • 62
    • 0030956532 scopus 로고    scopus 로고
    • P53 and Bax activation in 6-hydroxydopamine-induce apoptosis in PC12 cells
    • Blum D., Wu Y., Nissou M.-F., Arnaud S., Benabid A. L., Verna J. M. p53 and Bax activation in 6-hydroxydopamine-induce apoptosis in PC12 cells. Brain Res. 751:1997;139-142.
    • (1997) Brain Res , vol.751 , pp. 139-142
    • Blum, D.1    Wu, Y.2    Nissou, M.-F.3    Arnaud, S.4    Benabid, A.L.5    Verna, J.M.6
  • 63
    • 0028609849 scopus 로고
    • Serotonin binding proteins: An In vitro Model System fro monoamine-related neurotoxicity
    • Vauquelin G., Jimenez Del Rio M., Velez Pardo C. Serotonin binding proteins: an In vitro Model System fro monoamine-related neurotoxicity. Ann NY Acad Sci. 738:1994;409-418.
    • (1994) Ann NY Acad Sci , vol.738 , pp. 409-418
    • Vauquelin, G.1    Jimenez Del Rio, M.2    Velez Pardo, C.3
  • 64
    • 0029582880 scopus 로고
    • Serotonin binding proteins 'SBP': Target proteins and tool for in vitro neurotoxicity studies
    • Jimenez Del Rio M., Velez Pardo C., Ebinger G., Vauquelin G. Serotonin binding proteins 'SBP': Target proteins and tool for in vitro neurotoxicity studies. Gen Pharmacol. 26:1995;1633-1641.
    • (1995) Gen Pharmacol , vol.26 , pp. 1633-1641
    • Jimenez Del Rio, M.1    Velez Pardo, C.2    Ebinger, G.3    Vauquelin, G.4
  • 65
    • 0027179333 scopus 로고
    • Binding of serotonin and dopamine to 'serotonin binding proteins' in bovine frontal cortex: Evidence for iron-induced oxidative mechanisms
    • Jimenez Del Rio M., Velez Pardo C., Pinxteren J., De Potter W., Ebinger G., Vauquelin G. Binding of serotonin and dopamine to 'serotonin binding proteins' in bovine frontal cortex: evidence for iron-induced oxidative mechanisms. Eur J Pharmacol. 247:1993;11-21.
    • (1993) Eur J Pharmacol , vol.247 , pp. 11-21
    • Jimenez Del Rio, M.1    Velez Pardo, C.2    Pinxteren, J.3    De Potter, W.4    Ebinger, G.5    Vauquelin, G.6
  • 66
    • 0028981643 scopus 로고
    • Fe2+-mediated binding of serotonin and dopamine to skeletal muscle actin: Resemblance to serotonin binding proteins
    • Velez Pardo C., Jimenez Del Rio M., Pinxteren J., De Potter W., Ebinger G., Vauquelin G. Fe2+-mediated binding of serotonin and dopamine to skeletal muscle actin: resemblance to serotonin binding proteins. Eur J Pharmacol. 288:1995;209-218.
    • (1995) Eur J Pharmacol , vol.288 , pp. 209-218
    • Velez Pardo, C.1    Jimenez Del Rio, M.2    Pinxteren, J.3    De Potter, W.4    Ebinger, G.5    Vauquelin, G.6
  • 67
    • 0027980352 scopus 로고
    • Interaction of serotonin- And dopamine-related neurotoxins with 'serotonin binding proteins' in bovine frontal cortex
    • Jimenez Del Rio M., Velez Pardo C., Pinxteren J., De Potter W., Ebinger G., Vauquelin G. Interaction of serotonin- and dopamine-related neurotoxins with 'serotonin binding proteins' in bovine frontal cortex. Biochem Pharmacol. 48:1994;253-258.
    • (1994) Biochem Pharmacol , vol.48 , pp. 253-258
    • Jimenez Del Rio, M.1    Velez Pardo, C.2    Pinxteren, J.3    De Potter, W.4    Ebinger, G.5    Vauquelin, G.6
  • 68
  • 69
    • 0028982274 scopus 로고
    • P21-ras as a common singnaling target of reactive free radicals and celular redox stress
    • Lander H. M., Ogiste J. S., Teng K. K., Novogrodsky A. p21-ras as a common singnaling target of reactive free radicals and celular redox stress. J Biol Chem. 270:1995;21195-21198.
    • (1995) J Biol Chem , vol.270 , pp. 21195-21198
    • Lander, H.M.1    Ogiste, J.S.2    Teng, K.K.3    Novogrodsky, A.4
  • 70
    • 0029055812 scopus 로고
    • The small GTP-binding proteins Racl and Cdc42 regulate the activity of the JNK/SAPK signalling pathway
    • Coso O. A., Chiariello M., Yu J.-C. The small GTP-binding proteins Racl and Cdc42 regulate the activity of the JNK/SAPK signalling pathway. Cell. 81:1995;1137-1146.
    • (1995) Cell , vol.81 , pp. 1137-1146
    • Coso, O.A.1    Chiariello, M.2    Yu, J.-C.3
  • 72
    • 0028167599 scopus 로고
    • NF-kB activation of p53
    • Wu H., Lozano G. NF-kB activation of p53. J Biol Chem. 269:1994;20067-20074.
    • (1994) J Biol Chem , vol.269 , pp. 20067-20074
    • Wu, H.1    Lozano, G.2
  • 73
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriprtional activator of human bax gene
    • Miyashita T., Reed J. C. Tumor suppressor p53 is a direct transcriprtional activator of human bax gene. Cell. 80:1995;293-299.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 74
    • 0030842085 scopus 로고    scopus 로고
    • Nuclear translocation of NF-κB is increased in dopaminergic neurons of pacients with Parkinson disease
    • Hunot S., Brugg B., Ricard D. Nuclear translocation of NF-κB is increased in dopaminergic neurons of pacients with Parkinson disease. Proc Natl Acad Sci. 94:1997;7531-7536.
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 7531-7536
    • Hunot, S.1    Brugg, B.2    Ricard, D.3
  • 75
    • 0030782177 scopus 로고    scopus 로고
    • Cytochrome c: Can't live with it can't live without it
    • Reed J. C. Cytochrome c: Can't live with it can't live without it. Cell. 91:1997;559-562.
    • (1997) Cell , vol.91 , pp. 559-562
    • Reed, J.C.1
  • 76
    • 0030300160 scopus 로고    scopus 로고
    • The pharmacology of B-type selective monoamine oxidase inhibitors; Milestone in (-)-deprenyl research
    • Magyar K., Szende B., Lengyel J., Tekes K. The pharmacology of B-type selective monoamine oxidase inhibitors; milestone in (-)-deprenyl research. J Neural Transm. Suppl 48:1996;29-43.
    • (1996) J Neural Transm , vol.48 , pp. 29-43
    • Magyar, K.1    Szende, B.2    Lengyel, J.3    Tekes, K.4
  • 77
    • 0010547649 scopus 로고    scopus 로고
    • Ann Neurol. 39:1996;37-45.
    • (1996) Ann Neurol , vol.39 , pp. 37-45
  • 78
    • 0030249286 scopus 로고    scopus 로고
    • Prevention of dopamine-induced cell death by thiol antioxidants: Possible implications for treatment of parkinson's disease
    • Offen D., Ziv I., Sternin H. Prevention of dopamine-induced cell death by thiol antioxidants: possible implications for treatment of parkinson's disease. Exp Neurol. 141:1996;32-39.
    • (1996) Exp Neurol , vol.141 , pp. 32-39
    • Offen, D.1    Ziv, I.2    Sternin, H.3
  • 79
    • 0024557734 scopus 로고
    • Transition metals, ferritin, glutathione, and ascorbic acid in Parkinsonian brains
    • Riederer P., Sofic E., Rausch W.-D. Transition metals, ferritin, glutathione, and ascorbic acid in Parkinsonian brains. J Neurochem. 52:1989;515-520.
    • (1989) J Neurochem , vol.52 , pp. 515-520
    • Riederer, P.1    Sofic, E.2    Rausch, W.-D.3


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