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Volumn 29, Issue 5, 2000, Pages 232-240

Endogenous TGF-β1 inhibits the growth and metastatic dissemination of rat oral carcinoma cell lines but enhances local bone resorption

Author keywords

Bone resorption; Differentiation; Keratinocyte; Metastasis; TGF

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

EID: 0033624954     PISSN: 09042512     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0714.2000.290507.x     Document Type: Article
Times cited : (8)

References (37)
  • 1
    • 0000116653 scopus 로고
    • The transforming growth factors
    • Roberts AB, Sporn MB, eds. Berlin: Springer Verlag
    • Roberts AB, Sporn MB. The transforming growth factors. In: Roberts AB, Sporn MB, eds. Peptide growth factors and their receptors I. Berlin: Springer Verlag, 1990; 419-72.
    • (1990) Peptide Growth Factors and Their Receptors I , pp. 419-472
    • Roberts, A.B.1    Sporn, M.B.2
  • 2
    • 0025222517 scopus 로고
    • The transforming growth factor-β family
    • Massague J. The transforming growth factor-β family. Annu Rev Cell Biol 1990; 6: 597-641.
    • (1990) Annu Rev Cell Biol , vol.6 , pp. 597-641
    • Massague, J.1
  • 3
    • 0025098903 scopus 로고
    • Transforming growth factors and the regulation of cell proliferation
    • Lyons RM, Moses HL. Transforming growth factors and the regulation of cell proliferation. Eur J Biochem 1990; 187: 467-73.
    • (1990) Eur J Biochem , vol.187 , pp. 467-473
    • Lyons, R.M.1    Moses, H.L.2
  • 4
    • 0031933224 scopus 로고    scopus 로고
    • Molecular and cell biology of TGF-β
    • Roberts AB. Molecular and cell biology of TGF-β. Miner Electrolyte Metab 1998; 24: 111-9.
    • (1998) Miner Electrolyte Metab , vol.24 , pp. 111-119
    • Roberts, A.B.1
  • 5
    • 0027421280 scopus 로고
    • Resistance to inhibition of cell growth by transforming growth factor-β and its role in oncogenesis
    • Fynan TM, Reiss M. Resistance to inhibition of cell growth by transforming growth factor-β and its role in oncogenesis. Crit Rev Oncog 1993; 4: 493-540.
    • (1993) Crit Rev Oncog , vol.4 , pp. 493-540
    • Fynan, T.M.1    Reiss, M.2
  • 6
    • 0032451414 scopus 로고    scopus 로고
    • Molecular mechanisms of transforming growth factor-β signalling
    • Hu PP-C, Datto MB, Wang X-F. Molecular mechanisms of transforming growth factor-β signalling. Endocr Rev 1998; 19: 349-63.
    • (1998) Endocr Rev , vol.19 , pp. 349-363
    • Hu, P.P.-C.1    Datto, M.B.2    Wang, X.-F.3
  • 7
    • 0026600577 scopus 로고
    • Transforming growth factor-β1 overproduction in prostate cancer: Effects on growth in vivo and in vitro
    • Steiner MS, Barrack ER. Transforming growth factor-β1 overproduction in prostate cancer: effects on growth in vivo and in vitro. Mol Endocrinol 1992; 6: 15-25.
    • (1992) Mol Endocrinol , vol.6 , pp. 15-25
    • Steiner, M.S.1    Barrack, E.R.2
  • 8
    • 0026656525 scopus 로고
    • Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor-beta-1
    • Arrick BA, Lopez AR, Elfman F, Ebner R, Damsky CH, Derynck R. Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor-beta-1. J Cell Biol 1992; 118: 715-26.
    • (1992) J Cell Biol , vol.118 , pp. 715-726
    • Arrick, B.A.1    Lopez, A.R.2    Elfman, F.3    Ebner, R.4    Damsky, C.H.5    Derynck, R.6
  • 9
    • 0027793115 scopus 로고
    • Evidence for a positive role of transforming growth factor-β in human breast cancer cell tumorigenesis
    • Arteaga CL, Dugger TC, Winnier AR, Forbes JT. Evidence for a positive role of transforming growth factor-β in human breast cancer cell tumorigenesis. J Cell Biochem 1993; 17G: 187-93.
    • (1993) J Cell Biochem , vol.17 G , pp. 187-193
    • Arteaga, C.L.1    Dugger, T.C.2    Winnier, A.R.3    Forbes, J.T.4
  • 10
    • 0027848683 scopus 로고
    • Increased transforming growth factor-β expression inhibits cell proliferation in vitro, yet increases tumorigenicity and tumor growth of meth A sarcoma cells
    • Chang H-L, Gillett N, Figari I, Lopez AR, Palladino MA, Derynck R. Increased transforming growth factor-β expression inhibits cell proliferation in vitro, yet increases tumorigenicity and tumor growth of meth A sarcoma cells. Cancer Res 1993; 53: 4391-8.
    • (1993) Cancer Res , vol.53 , pp. 4391-4398
    • Chang, H.-L.1    Gillett, N.2    Figari, I.3    Lopez, A.R.4    Palladino, M.A.5    Derynck, R.6
  • 11
    • 0027983685 scopus 로고
    • Transforming growth factor-β: Antisense RNA-mediated inhibition affects anchorage-independent growth, tumorigenicity, and tumour-infiltrating T-cells in malignant mesothelioma
    • Fitzpatrick DR, Bielefeldt-Ohmann H, Himbeck RP, Jarnicki AG, Marzo AL, Robinson BWS. Transforming growth factor-β: antisense RNA-mediated inhibition affects anchorage-independent growth, tumorigenicity, and tumour-infiltrating T-cells in malignant mesothelioma. Growth Factors 1994; 11: 29-44.
    • (1994) Growth Factors , vol.11 , pp. 29-44
    • Fitzpatrick, D.R.1    Bielefeldt-Ohmann, H.2    Himbeck, R.P.3    Jarnicki, A.G.4    Marzo, A.L.5    Robinson, B.W.S.6
  • 12
    • 0028820153 scopus 로고
    • Transforming growth factor-β1 (TGF-β1) is an autocrine positive regulator of colon carcinoma U9 cells in vivo as shown by transfection of a TGF-β1 antisense expression plasmid
    • Huang F, Newman E, Theodorescu D, Kerbel RS, Friedman E. Transforming growth factor-β1 (TGF-β1) is an autocrine positive regulator of colon carcinoma U9 cells in vivo as shown by transfection of a TGF-β1 antisense expression plasmid. Cell Growth Differ 1995; 6: 1635-42.
    • (1995) Cell Growth Differ , vol.6 , pp. 1635-1642
    • Huang, F.1    Newman, E.2    Theodorescu, D.3    Kerbel, R.S.4    Friedman, E.5
  • 13
    • 0030639334 scopus 로고    scopus 로고
    • Expression of an antisense transforming growth factor-β1 transgene reduces tumorigenicity of EMT6 mammary tumour cells
    • Park JA, Wang E, Kurt RA, Scluter SF, Hersh EM, Akporiaye ET. Expression of an antisense transforming growth factor-β1 transgene reduces tumorigenicity of EMT6 mammary tumour cells. Cancer Gene Ther 1997; 4: 42-50.
    • (1997) Cancer Gene Ther , vol.4 , pp. 42-50
    • Park, J.A.1    Wang, E.2    Kurt, R.A.3    Scluter, S.F.4    Hersh, E.M.5    Akporiaye, E.T.6
  • 14
    • 0026513154 scopus 로고
    • TGF-β1 is an autocrine-negative regulator of human colon FET cells in vivo as revealed by transfection of an antisense expression vector
    • Wu S, Theordorescu D, Kerbel RS, et al. TGF-β1 is an autocrine-negative regulator of human colon FET cells in vivo as revealed by transfection of an antisense expression vector. J Cell Biol 1992; 116: 187-96.
    • (1992) J Cell Biol , vol.116 , pp. 187-196
    • Wu, S.1    Theordorescu, D.2    Kerbel, R.S.3
  • 15
    • 0027548803 scopus 로고
    • Repression of autocrine transforming growth factor-β1 and -β2 in quiescent CBS colon carcinoma cells leads to progression of tumorigenic properties
    • Wu SP, Sun L-Z, Willson JKV, Humphrey L, Kerbel R, Brattain MG. Repression of autocrine transforming growth factor-β1 and -β2 in quiescent CBS colon carcinoma cells leads to progression of tumorigenic properties. Cell Growth Differ 1993; 4: 115-23.
    • (1993) Cell Growth Differ , vol.4 , pp. 115-123
    • Wu, S.P.1    Sun, L.-Z.2    Willson, J.K.V.3    Humphrey, L.4    Kerbel, R.5    Brattain, M.G.6
  • 16
    • 0029010734 scopus 로고
    • Mammary tumor suppression by transforming growth factor-β1 transgene expression
    • Pierce DF, Gorska AE, Chytil A, et al. Mammary tumor suppression by transforming growth factor-β1 transgene expression. Proc Natl Acad Sci USA 1995; 92: 4254-8.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4254-4258
    • Pierce, D.F.1    Gorska, A.E.2    Chytil, A.3
  • 17
    • 0030798673 scopus 로고    scopus 로고
    • Overexpression of autocrine TGF-β1 suppresses the growth of spindle epithelial cells in vitro and in vivo in the rat 4NQO model of oral carcinogenesis
    • Davies M, Prime SS, Stone AM, et al. Overexpression of autocrine TGF-β1 suppresses the growth of spindle epithelial cells in vitro and in vivo in the rat 4NQO model of oral carcinogenesis. Int Cancer 1997; 73: 68-74.
    • (1997) Int Cancer , vol.73 , pp. 68-74
    • Davies, M.1    Prime, S.S.2    Stone, A.M.3
  • 18
    • 0027217314 scopus 로고
    • Loss of expression of transforming growth factor-β in skin and skin tumours is associated with hyperproliferation and a high risk for malignant conversion
    • Glick AB, Kulkarni AB, Tennenbaum T, et al. Loss of expression of transforming growth factor-β in skin and skin tumours is associated with hyperproliferation and a high risk for malignant conversion. Proc Natl Acad Sci USA 1993; 90: 6076-80.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6076-6080
    • Glick, A.B.1    Kulkarni, A.B.2    Tennenbaum, T.3
  • 19
    • 0029784956 scopus 로고    scopus 로고
    • Dysregulation of autocrine TGF-β isoform production and ligand responses in human tumour-derived and Ha-ras-transfected keratinocytes and fibroblasts
    • Fahey MS, Paterson IC, Stone A, et al. Dysregulation of autocrine TGF-β isoform production and ligand responses in human tumour-derived and Ha-ras-transfected keratinocytes and fibroblasts. Br J Cancer 1996; 74: 1074-80.
    • (1996) Br J Cancer , vol.74 , pp. 1074-1080
    • Fahey, M.S.1    Paterson, I.C.2    Stone, A.3
  • 21
    • 0028171401 scopus 로고
    • Targeted deletion of the TGF-β1 gene causes rapid progression to squamous cell carcinoma
    • Glick AB, Lee MM, Darwiche N, Kulkarni AB, Karlsson S, Yuspa SH. Targeted deletion of the TGF-β1 gene causes rapid progression to squamous cell carcinoma. Genes Dev 1994; 8: 2429-40.
    • (1994) Genes Dev , vol.8 , pp. 2429-2440
    • Glick, A.B.1    Lee, M.M.2    Darwiche, N.3    Kulkarni, A.B.4    Karlsson, S.5    Yuspa, S.H.6
  • 22
    • 0028986244 scopus 로고
    • Concerted action of TGF-beta 1 and its type II receptor in control of epidermal homeostasis in transgenic mice
    • Cui W, Fowlis DJ, Cousins FM, et al. Concerted action of TGF-beta 1 and its type II receptor in control of epidermal homeostasis in transgenic mice. Genes Dev 1995; 9: 945-55.
    • (1995) Genes Dev , vol.9 , pp. 945-955
    • Cui, W.1    Fowlis, D.J.2    Cousins, F.M.3
  • 23
    • 0029802491 scopus 로고    scopus 로고
    • Altered epidermal cell growth control in vivo by inducible expression of transforming growth factor-β1 in the skin of transgenic mice
    • Fowlis DJ, Cui W, Johnson SA, Balmain A, Akhurst RJ. Altered epidermal cell growth control in vivo by inducible expression of transforming growth factor-β1 in the skin of transgenic mice. Cell Growth Differ 1996; 7: 679-87.
    • (1996) Cell Growth Differ , vol.7 , pp. 679-687
    • Fowlis, D.J.1    Cui, W.2    Johnson, S.A.3    Balmain, A.4    Akhurst, R.J.5
  • 24
    • 0030598681 scopus 로고    scopus 로고
    • TGF-β1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice
    • Cui W, Fowlis DJ, Bryson S, et al. TGF-β1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice. Cell 1996; 86; 531-42.
    • (1996) Cell , vol.86 , pp. 531-542
    • Cui, W.1    Fowlis, D.J.2    Bryson, S.3
  • 25
    • 0028603343 scopus 로고
    • TGF-β induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type I receptors
    • Miettinen PJ, Ebner R, Lopez AR, Derynck R. TGF-β induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors. J Cell Biol 1994; 127: 2021-36.
    • (1994) J Cell Biol , vol.127 , pp. 2021-2036
    • Miettinen, P.J.1    Ebner, R.2    Lopez, A.R.3    Derynck, R.4
  • 27
    • 0029664520 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transformation of a newly established cell line from ovarian adenosarcoma by transforming growth factor-β1
    • Kitagawa K, Murata A, Matsuura N, et al. Epithelial-mesenchymal transformation of a newly established cell line from ovarian adenosarcoma by transforming growth factor-β1. Int J Cancer 1996; 66: 91-7.
    • (1996) Int J Cancer , vol.66 , pp. 91-97
    • Kitagawa, K.1    Murata, A.2    Matsuura, N.3
  • 28
    • 0029662049 scopus 로고    scopus 로고
    • TGF-β1 and Ha-ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumour cells
    • Oft M, Peli J, Rudaz C, Schwartz H, Beug H, Reichmann E. TGF-β1 and Ha-ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumour cells. Genes Dev 1996; 10: 2462-77.
    • (1996) Genes Dev , vol.10 , pp. 2462-2477
    • Oft, M.1    Peli, J.2    Rudaz, C.3    Schwartz, H.4    Beug, H.5    Reichmann, E.6
  • 29
    • 0031817391 scopus 로고    scopus 로고
    • Transforming growth factor-β is essential for spindle cell conversion of mouse skin carcinoma in vivo: Implications for tumour invasion
    • Portella G, Cumming SA, Liddell J, et al. Transforming growth factor-β is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumour invasion. Cell Growth Differ 1998; 9: 393-404.
    • (1998) Cell Growth Differ , vol.9 , pp. 393-404
    • Portella, G.1    Cumming, S.A.2    Liddell, J.3
  • 30
    • 0028890175 scopus 로고
    • Loss of expression of basement membrane proteins reflects anomalies of chromosomes 3 and 12 in the rat 4-nitroquinoline-N-oxide model of oral carcinogenesis
    • Patel V, Poulopoulos AK, Levan G, Game SM, Eveson JW, Prime SS. Loss of expression of basement membrane proteins reflects anomalies of chromosomes 3 and 12 in the rat 4-nitroquinoline-N-oxide model of oral carcinogenesis. Carcinogenesis 1995; 16: 17-23.
    • (1995) Carcinogenesis , vol.16 , pp. 17-23
    • Patel, V.1    Poulopoulos, A.K.2    Levan, G.3    Game, S.M.4    Eveson, J.W.5    Prime, S.S.6
  • 31
    • 0033213421 scopus 로고    scopus 로고
    • Loss of differentiation of 4NQO-induced rat malignant oral keratinocytes correlates with metastatic dissemination and is associated with a reduced cellular response to TGF-β1 and an altered receptor profile
    • Davies M, Paterson, IC, Stone A, et al. Loss of differentiation of 4NQO-induced rat malignant oral keratinocytes correlates with metastatic dissemination and is associated with a reduced cellular response to TGF-β1 and an altered receptor profile. J Oral Pathol Med 1999; 28: 397-405.
    • (1999) J Oral Pathol Med , vol.28 , pp. 397-405
    • Davies, M.1    Paterson, I.C.2    Stone, A.3
  • 32
    • 0025362139 scopus 로고
    • Tumour progression in experimental oral carcinogenesis is associated with changes in EGF and TGF-β receptor expression and altered responses to these growth factors
    • Game SM, Stone A, Scully C, Prime SS. Tumour progression in experimental oral carcinogenesis is associated with changes in EGF and TGF-β receptor expression and altered responses to these growth factors. Carcinogenesis 1990; 11: 965-73.
    • (1990) Carcinogenesis , vol.11 , pp. 965-973
    • Game, S.M.1    Stone, A.2    Scully, C.3    Prime, S.S.4
  • 33
    • 0025860394 scopus 로고
    • Differentiation of malignant oral rat keratinocyte reflects changes in EGF and TGF-β receptor expression but not growth factor dependence
    • Game SM, Stone A, Matthews JB, Scully C, Prime SS. Differentiation of malignant oral rat keratinocyte reflects changes in EGF and TGF-β receptor expression but not growth factor dependence. Carcinogenesis 1991; 12: 409-16.
    • (1991) Carcinogenesis , vol.12 , pp. 409-416
    • Game, S.M.1    Stone, A.2    Matthews, J.B.3    Scully, C.4    Prime, S.S.5
  • 34
    • 0032918414 scopus 로고    scopus 로고
    • TGF-β signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development
    • Yin JJ, Selander K, Chirgwin JM, et al. TGF-β signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development. J Clin Invest 1999; 103: 197-206.
    • (1999) J Clin Invest , vol.103 , pp. 197-206
    • Yin, J.J.1    Selander, K.2    Chirgwin, J.M.3
  • 35
    • 0032547895 scopus 로고    scopus 로고
    • TGFß signaling is necessary for carcinoma cell invasiveness and metastasis
    • Oft M, Heider K-H, Beug H. TGFß signaling is necessary for carcinoma cell invasiveness and metastasis. Curr Biol 1998; 8: 1243-52.
    • (1998) Curr Biol , vol.8 , pp. 1243-1252
    • Oft, M.1    Heider, K.-H.2    Beug, H.3
  • 36
    • 0029549836 scopus 로고
    • Infrequent Ha-ras mutations and absence of Ki-ras, N-ras, and p53 mutations in 4-nitroquinoline 1-oxide-induced rat oral lesions
    • Suzui M, Yoshimi N, Tanaka T, Mori H. Infrequent Ha-ras mutations and absence of Ki-ras, N-ras, and p53 mutations in 4-nitroquinoline 1-oxide-induced rat oral lesions. Mol Carcinog 1995; 14: 294-8.
    • (1995) Mol Carcinog , vol.14 , pp. 294-298
    • Suzui, M.1    Yoshimi, N.2    Tanaka, T.3    Mori, H.4
  • 37
    • 0028072696 scopus 로고
    • Harvey Ras (H-ras) point mutations are induced by 4-nitroquinoline-1-oxide in murine oral squamous epithelia, while squamous cell carcinomas and loss of heterozygosity occur without additional exposure
    • Yuan B, Heniford BW, Ackermann DM, Hawkins BL, Hendler FJ. Harvey Ras (H-ras) point mutations are induced by 4-nitroquinoline-1-oxide in murine oral squamous epithelia, while squamous cell carcinomas and loss of heterozygosity occur without additional exposure. Cancer Res 1994; 54: 5310-7.
    • (1994) Cancer Res , vol.54 , pp. 5310-5317
    • Yuan, B.1    Heniford, B.W.2    Ackermann, D.M.3    Hawkins, B.L.4    Hendler, F.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.