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Volumn 18, Issue 3, 2000, Pages 241-248

The role of the 11β-hydroxysteroid dehydrogenase type 2 in human hypertension

Author keywords

11 hydroxysteroid dehydrogenase type 2; Apparent mineralocorticoid excess; Genetics; Hypertension; Mineralocorticoid receptor; Renal sodium retention

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; ALDOSTERONE; CARBENOXOLONE; CORTISONE; GLYCYRRHETINIC ACID; GOSSYPOL; HYDROCORTISONE; HYDROXYSTEROID; MICROSATELLITE DNA; MINERALOCORTICOID; MINERALOCORTICOID RECEPTOR; POTASSIUM; RENIN; SODIUM; SODIUM CHLORIDE; GLUCOCORTICOID; HYDROXYSTEROID DEHYDROGENASE;

EID: 0033622032     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-200018030-00001     Document Type: Review
Times cited : (85)

References (75)
  • 1
    • 0023743171 scopus 로고
    • Mineralocorticoid action: Target tissue specificity is enzyme, not receptor, mediated
    • 1 Funder JW, Pearce PT, Smith R, Smith AI. Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated. Science 1988; 242:583-585.
    • (1988) Science , vol.242 , pp. 583-585
    • Funder, J.W.1    Pearce, P.T.2    Smith, R.3    Smith, A.I.4
  • 2
    • 0023761690 scopus 로고
    • Localisation of 11β-hydroxysteroid dehydrogenase-tissue specific protector of the mineralocorticoid receptor
    • 2 Edwards CR, Stewart PM, Burt D, Brett L, McIntyre MA, Sutano WS, et al. Localisation of 11β-hydroxysteroid dehydrogenase-tissue specific protector of the mineralocorticoid receptor. Lancet 1988; 11:986-989
    • (1988) Lancet , vol.11 , pp. 986-989
    • Edwards, C.R.1    Stewart, P.M.2    Burt, D.3    Brett, L.4    McIntyre, M.A.5    Sutano, W.S.6
  • 3
    • 0025222242 scopus 로고
    • Apparent mineralocorticoid excess, pseudohypoaldosteronism, and urinary electrolyte excretion: Toward a redefinition of mineralocorticoid action
    • 3 Funder JW, Pearce PT, Myles K, Roy LP. Apparent mineralocorticoid excess, pseudohypoaldosteronism, and urinary electrolyte excretion: toward a redefinition of mineralocorticoid action. FASEB J 1990; 4:3234-3238.
    • (1990) FASEB J , vol.4 , pp. 3234-3238
    • Funder, J.W.1    Pearce, P.T.2    Myles, K.3    Roy, L.P.4
  • 4
    • 0030749702 scopus 로고    scopus 로고
    • Tumor necrosis factor α and interleucin 1β enhance the cortisone/cortisol shuttle
    • 4 Escher G, Galli I, Vishwanath BS, Frey BM, Frey FJ. Tumor necrosis factor α and interleucin 1β enhance the cortisone/cortisol shuttle. J Exp Med 1997; 186:189-198.
    • (1997) J Exp Med , vol.186 , pp. 189-198
    • Escher, G.1    Galli, I.2    Vishwanath, B.S.3    Frey, B.M.4    Frey, F.J.5
  • 5
    • 0024789306 scopus 로고
    • Cloning and expression of rat cDNA encoding corticosteroid 11β-dehydrogenase
    • 5 Agarwal AK, Monder C, Eckstein B, White PC. Cloning and expression of rat cDNA encoding corticosteroid 11β-dehydrogenase. J Biol Chem 1989; 264:18939-18943.
    • (1989) J Biol Chem , vol.264 , pp. 18939-18943
    • Agarwal, A.K.1    Monder, C.2    Eckstein, B.3    White, P.C.4
  • 6
    • 0026095840 scopus 로고
    • The human gene for 11β-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization
    • 6 Tannin GM, Agarwal AK, Monder C, New MI, White PC. The human gene for 11β-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization. J Biol Chem 1991; 266:16653-16658.
    • (1991) J Biol Chem , vol.266 , pp. 16653-16658
    • Tannin, G.M.1    Agarwal, A.K.2    Monder, C.3    New, M.I.4    White, P.C.5
  • 7
    • 0026671792 scopus 로고
    • Tissue-specific distribution of the NAD+ dependent isoform of 11β-hydroxysteroid dehydrogenase
    • 7 Walker BR, Campbell JC, Williams BC, Edwards CRW. Tissue-specific distribution of the NAD+ dependent isoform of 11β-hydroxysteroid dehydrogenase. Endocrinology 1992; 131:970-972.
    • (1992) Endocrinology , vol.131 , pp. 970-972
    • Walker, B.R.1    Campbell, J.C.2    Williams, B.C.3    Edwards, C.R.W.4
  • 8
    • 0028034209 scopus 로고
    • Cloning and tissue distribution of the human 11β-hydroxysteroid dehydrogenase type 2 enzyme
    • 8 Albiston AL, Obeyesekere VR, Smith RE, Krozowski ZS. Cloning and tissue distribution of the human 11β-hydroxysteroid dehydrogenase type 2 enzyme. Mol Cell Endocrinol 1994; 105:R11-R17.
    • (1994) Mol Cell Endocrinol , vol.105
    • Albiston, A.L.1    Obeyesekere, V.R.2    Smith, R.E.3    Krozowski, Z.S.4
  • 9
    • 0028081325 scopus 로고
    • NAD+-dependent isoform of 11β-hydroxysteroid dehydrogenase. Cloning and characterization of cDNA from sheep kidney
    • 9 Agarwal AK, Mune T, Monder C, White PC. NAD+-dependent isoform of 11β-hydroxysteroid dehydrogenase. Cloning and characterization of cDNA from sheep kidney. J Biol Chem 1994; 269:25959-25962.
    • (1994) J Biol Chem , vol.269 , pp. 25959-25962
    • Agarwal, A.K.1    Mune, T.2    Monder, C.3    White, P.C.4
  • 10
    • 0030920285 scopus 로고    scopus 로고
    • Oxoreductase and dehydrogenase activities of the cloned 11β-hydroxysteroid dehydrogenase type 2 enzyme
    • 10 Li KXS, Obeyesekere VR, Krozowski ZS, Ferrari P. Oxoreductase and dehydrogenase activities of the cloned 11β-hydroxysteroid dehydrogenase type 2 enzyme. Endocrinology 1997; 138:2948-2952.
    • (1997) Endocrinology , vol.138 , pp. 2948-2952
    • Li, K.X.S.1    Obeyesekere, V.R.2    Krozowski, Z.S.3    Ferrari, P.4
  • 12
    • 0031594579 scopus 로고    scopus 로고
    • Reduced 11β-hydroxysteroid dehydrogenase activity in the remaining kidney following nephrectomy
    • 12 Escher G, Vogt B, Beck T, Guntern D, Frey BM, Frey FJ. Reduced 11β-hydroxysteroid dehydrogenase activity in the remaining kidney following nephrectomy. Endocrinology 1998; 139:1533-1539.
    • (1998) Endocrinology , vol.139 , pp. 1533-1539
    • Escher, G.1    Vogt, B.2    Beck, T.3    Guntern, D.4    Frey, B.M.5    Frey, F.J.6
  • 13
    • 0027175394 scopus 로고
    • Liquorice inhibits 11β-hydroxysteroid dehydrogenase messenger ribonucleic acid levels and potentiates glucocorticoid hormone action
    • 13 Whorwood C, Sheppard MC, Stewart PM. Liquorice inhibits 11β-hydroxysteroid dehydrogenase messenger ribonucleic acid levels and potentiates glucocorticoid hormone action. Endocrinology 1993; 132:2287-2292.
    • (1993) Endocrinology , vol.132 , pp. 2287-2292
    • Whorwood, C.1    Sheppard, M.C.2    Stewart, P.M.3
  • 15
    • 0026586125 scopus 로고
    • Regulation of apical membrane Na and K channels in rat renal collecting tubules by aldosterone
    • 15 Palmer LG, Frindt G. Regulation of apical membrane Na and K channels in rat renal collecting tubules by aldosterone. Semin Nephrol 1992; 12:37-43.
    • (1992) Semin Nephrol , vol.12 , pp. 37-43
    • Palmer, L.G.1    Frindt, G.2
  • 16
    • 0026692172 scopus 로고
    • Aldosterone regulation of gene transcription leading to control of ion transport
    • 16 Horisberger JD, Rossier BC. Aldosterone regulation of gene transcription leading to control of ion transport. Hypertension 1992; 19:221-227.
    • (1992) Hypertension , vol.19 , pp. 221-227
    • Horisberger, J.D.1    Rossier, B.C.2
  • 18
    • 0028939802 scopus 로고
    • Nongenomic aldosterone effects: The cell membrane as a specific target of mineralocorticoid action
    • 18 Wehling M. Nongenomic aldosterone effects: the cell membrane as a specific target of mineralocorticoid action. Steroids 1995; 60:153-156.
    • (1995) Steroids , vol.60 , pp. 153-156
    • Wehling, M.1
  • 19
    • 0023221667 scopus 로고
    • Cloning of human mineralocorticoid receptor complementary DNA: Structural and functional kinship with the glucocorticoid receptor
    • 19 Arriza JL, Weinberger C, Cerelli G, Glaser TM, Handelin BL, Housman DE, et al. Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor. Science 1987; 237:268-275.
    • (1987) Science , vol.237 , pp. 268-275
    • Arriza, J.L.1    Weinberger, C.2    Cerelli, G.3    Glaser, T.M.4    Handelin, B.L.5    Housman, D.E.6
  • 20
    • 0031283178 scopus 로고    scopus 로고
    • 11β-Hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress
    • 20 Kotelevtsev Y, Holmes MC, Burchell A, Houston PM, Schmoll D, Jamieson P, et al. 11β-Hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress. Proc Natl Acad Sci USA 1997; 94:14924-14929.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 14924-14929
    • Kotelevtsev, Y.1    Holmes, M.C.2    Burchell, A.3    Houston, P.M.4    Schmoll, D.5    Jamieson, P.6
  • 23
    • 0017711792 scopus 로고
    • Evidence for an unidentified steroid in a child with apparent mineralocorticoid hypertension
    • 23 New MI, Levine LS, Biglieri EG, Pareira J, Ulick S. Evidence for an unidentified steroid in a child with apparent mineralocorticoid hypertension. J Clin Endocrinol Metab 1977; 44:924-933.
    • (1977) J Clin Endocrinol Metab , vol.44 , pp. 924-933
    • New, M.I.1    Levine, L.S.2    Biglieri, E.G.3    Pareira, J.4    Ulick, S.5
  • 24
    • 0018598286 scopus 로고
    • A syndrome of apparent mineralocorticoid excess associated with defects in the peripheral metabolism of cortisol
    • 24 Ulick S, Levine SL, Gunczler P, Zanconato G, Ramirez LC, Rauh W, et al. A syndrome of apparent mineralocorticoid excess associated with defects in the peripheral metabolism of cortisol. J Clin Endocrinol Metab 1979; 49:757-763.
    • (1979) J Clin Endocrinol Metab , vol.49 , pp. 757-763
    • Ulick, S.1    Levine, S.L.2    Gunczler, P.3    Zanconato, G.4    Ramirez, L.C.5    Rauh, W.6
  • 25
    • 0029160972 scopus 로고
    • Human hypertension caused by mutations in the kidney isozyme of 11β-hydroxysteroid dehydrogenase
    • 25 Mune T, Rogerson FM, Nikkila H, Agarwal AK, White PC. Human hypertension caused by mutations in the kidney isozyme of 11β-hydroxysteroid dehydrogenase. Nature Genetics 1995; 10:394-399.
    • (1995) Nature Genetics , vol.10 , pp. 394-399
    • Mune, T.1    Rogerson, F.M.2    Nikkila, H.3    Agarwal, A.K.4    White, P.C.5
  • 29
    • 0029954797 scopus 로고    scopus 로고
    • Point mutations abolish 11β-hydroxysteroid dehydrogenase type II activity in three families with the congenital syndrome of apparent mineralocorticoid excess
    • 29 Ferrari P, Obeyesekere VR, Li K, Wilson RC, New MI, Funder JW, Krozowski ZS. Point mutations abolish 11β-hydroxysteroid dehydrogenase type II activity in three families with the congenital syndrome of apparent mineralocorticoid excess. Mol Cell Endocrinol 1996; 119:21-24.
    • (1996) Mol Cell Endocrinol , vol.119 , pp. 21-24
    • Ferrari, P.1    Obeyesekere, V.R.2    Li, K.3    Wilson, R.C.4    New, M.I.5    Funder, J.W.6    Krozowski, Z.S.7
  • 30
    • 0029935189 scopus 로고    scopus 로고
    • The 11β-hydroxysteroid dehydrogenase type II enzyme: Biochemical consequences of the congenital R337C mutation
    • 30 Ferrari P, Obeyesekere VR, Li K, Andrews RK, Krozowski ZS. The 11β-hydroxysteroid dehydrogenase type II enzyme: biochemical consequences of the congenital R337C mutation. Steroids 1996; 61:197-200.
    • (1996) Steroids , vol.61 , pp. 197-200
    • Ferrari, P.1    Obeyesekere, V.R.2    Li, K.3    Andrews, R.K.4    Krozowski, Z.S.5
  • 31
    • 0030049329 scopus 로고
    • Human hypertension in the syndrome of apparent mineralocorticoid excess due to mutation of the 11β-hydroxysteroid dehydrogenase type 2 gene
    • 31 Stewart PM, Krozowski ZS, Gupta A, Milford DV, Howie AJ, Sheppard MC, et al. Human hypertension in the syndrome of apparent mineralocorticoid excess due to mutation of the 11β-hydroxysteroid dehydrogenase type 2 gene. Lancet 1995; 1:88-91.
    • (1995) Lancet , vol.1 , pp. 88-91
    • Stewart, P.M.1    Krozowski, Z.S.2    Gupta, A.3    Milford, D.V.4    Howie, A.J.5    Sheppard, M.C.6
  • 32
    • 0030833094 scopus 로고    scopus 로고
    • A new compound heterozygous mutation in the 11β-hydroxysteroid dehydrogenase type 2 gene in a case of apparent mineralocorticoid excess
    • 32 Kitanaka S, Katsumata N, Tanae A, Hibi I, Takeyama K, Fuse H, et al. A new compound heterozygous mutation in the 11β-hydroxysteroid dehydrogenase type 2 gene in a case of apparent mineralocorticoid excess. J Clin Endocrinol Metab 1997; 82:4054-4058.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 4054-4058
    • Kitanaka, S.1    Katsumata, N.2    Tanae, A.3    Hibi, I.4    Takeyama, K.5    Fuse, H.6
  • 33
    • 6844237653 scopus 로고    scopus 로고
    • Apparent mineralocorticoid excess in a Brazilian kindred: Hypertension in the heterozygote state
    • 33 Li A, Li KXZ, Marui S, Krozowski ZS, Batista MC, Whorwood CB, et al. Apparent mineralocorticoid excess in a Brazilian kindred: hypertension in the heterozygote state. J Hypertens 1997; 15:1397-1402.
    • (1997) J Hypertens , vol.15 , pp. 1397-1402
    • Li, A.1    Li, K.X.Z.2    Marui, S.3    Krozowski, Z.S.4    Batista, M.C.5    Whorwood, C.B.6
  • 36
    • 85084959584 scopus 로고    scopus 로고
    • A mutation in the cofactor binding domain of the renal 11β-hydroxysteroid dehydrogenase type 2 causing mineralocorticoid hypertension
    • 36 Odermatt A, Arnold P, Repetto H, Dick B, Frey BM, Frey FJ, et al. A mutation in the cofactor binding domain of the renal 11β-hydroxysteroid dehydrogenase type 2 causing mineralocorticoid hypertension [abstract]. J Am Soc Nephrol 1999; 10:352A.
    • (1999) J Am Soc Nephrol , vol.10
    • Odermatt, A.1    Arnold, P.2    Repetto, H.3    Dick, B.4    Frey, B.M.5    Frey, F.J.6
  • 37
    • 0032231654 scopus 로고    scopus 로고
    • Molecular basis for hypertension in the 'type II variant' of apparent mineralocorticoid excess
    • 37 Li A, Tedde R, Krozowski ZS, Pala A, Li KXZ, Shackleton CHL, et al. Molecular basis for hypertension in the 'type II variant' of apparent mineralocorticoid excess. Am J Hum Genet 1998; 63:370-379.
    • (1998) Am J Hum Genet , vol.63 , pp. 370-379
    • Li, A.1    Tedde, R.2    Krozowski, Z.S.3    Pala, A.4    Li, K.X.Z.5    Shackleton, C.H.L.6
  • 39
    • 0023242981 scopus 로고
    • Mineralocorticoid activity of liquorice: 11β-hydroxysteroid dehydrogenase deficiency comes of age
    • 39 Stewart PM, Wallace AM, Valentino R, Burt D, Shackleton CH, Edwards CR. Mineralocorticoid activity of liquorice: 11β-hydroxysteroid dehydrogenase deficiency comes of age. Lancet 1987; 2:821-824.
    • (1987) Lancet , vol.2 , pp. 821-824
    • Stewart, P.M.1    Wallace, A.M.2    Valentino, R.3    Burt, D.4    Shackleton, C.H.5    Edwards, C.R.6
  • 40
    • 0020373539 scopus 로고
    • The relation of arterial pressure with plasma and body electrolytes is similar in Conn's syndrome and essential hypertension
    • 40 Beretta-Piccoli C, Davies DL, Boddy K, Brown JJ, Cumming AM, East BW, et al. The relation of arterial pressure with plasma and body electrolytes is similar in Conn's syndrome and essential hypertension. Clin Sci 1982; 63:89-92.
    • (1982) Clin Sci , vol.63 , pp. 89-92
    • Beretta-Piccoli, C.1    Davies, D.L.2    Boddy, K.3    Brown, J.J.4    Cumming, A.M.5    East, B.W.6
  • 41
    • 0027320739 scopus 로고
    • Deficient inactivation of cortisol by 11β-hydroxysteroid dehydrogenase in essential hypertension
    • 41 Walker BR, Stewart PM, Shackleton C, Padfield PL, Edwards C. Deficient inactivation of cortisol by 11β-hydroxysteroid dehydrogenase in essential hypertension. Clin Endocrinol 1993; 39:221-227.
    • (1993) Clin Endocrinol , vol.39 , pp. 221-227
    • Walker, B.R.1    Stewart, P.M.2    Shackleton, C.3    Padfield, P.L.4    Edwards, C.5
  • 42
    • 0028967443 scopus 로고
    • Evidence of coexisting changes in 11β-hydroxysteroid dehydrogenase and 5β-reductase activity in subjects with untreated essential hypertension
    • 42 Soro A, Ingram MC, Tonolo G, Glorioso N, Fraser R. Evidence of coexisting changes in 11β-hydroxysteroid dehydrogenase and 5β-reductase activity in subjects with untreated essential hypertension. Hypertension 1995; 25:67-70.
    • (1995) Hypertension , vol.25 , pp. 67-70
    • Soro, A.1    Ingram, M.C.2    Tonolo, G.3    Glorioso, N.4    Fraser, R.5
  • 43
    • 0030023440 scopus 로고    scopus 로고
    • Increased vasoconstrictor sensitivity to glucocorticoid in essential hypertension
    • 43 Walker BR, Best R, Shackleton CH, Padfield PL, Edwards CR. Increased vasoconstrictor sensitivity to glucocorticoid in essential hypertension. Hypertension 1996; 27:190-196.
    • (1996) Hypertension , vol.27 , pp. 190-196
    • Walker, B.R.1    Best, R.2    Shackleton, C.H.3    Padfield, P.L.4    Edwards, C.R.5
  • 46
    • 0028173045 scopus 로고
    • The activities of 5β-reductase and 11β-hydroxysteroid dehydrogenase in essential hypertension
    • 46 Iki K, Miyamori I, Hatakeyama H, Yoneda T, Takeda Y, Takeda R, et al. The activities of 5β-reductase and 11β-hydroxysteroid dehydrogenase in essential hypertension. Steroids 1994; 59:656-660.
    • (1994) Steroids , vol.59 , pp. 656-660
    • Iki, K.1    Miyamori, I.2    Hatakeyama, H.3    Yoneda, T.4    Takeda, Y.5    Takeda, R.6
  • 47
    • 0029064934 scopus 로고
    • Cortisol metabolism in hypertensive patients who do and do not develop hypokalemia from diuretics
    • 47 Santini DL, Lorenzo BJ, Koufis T, Reidenberg MM. Cortisol metabolism in hypertensive patients who do and do not develop hypokalemia from diuretics. Am J Hypertens 1995; 8:516-519.
    • (1995) Am J Hypertens , vol.8 , pp. 516-519
    • Santini, D.L.1    Lorenzo, B.J.2    Koufis, T.3    Reidenberg, M.M.4
  • 48
    • 0025929456 scopus 로고
    • Salt sensitivity. Definition, conception, methodology and long-term issues
    • 48 Sullivan JM. Salt sensitivity. Definition, conception, methodology and long-term issues. Hypertension 1991; 17 (Suppl. 1):61-68.
    • (1991) Hypertension , vol.17 , Issue.SUPPL. 1 , pp. 61-68
    • Sullivan, J.M.1
  • 49
    • 0029928474 scopus 로고    scopus 로고
    • Salt sensitivity of blood pressure in humans
    • 49 Weinberger MH. Salt sensitivity of blood pressure in humans. Hypertension 1996; 27:481-490.
    • (1996) Hypertension , vol.27 , pp. 481-490
    • Weinberger, M.H.1
  • 50
    • 0029944160 scopus 로고    scopus 로고
    • Salt sensitivity as a phenotype for genetic studies of human hypertension
    • 50 Sharma AM. Salt sensitivity as a phenotype for genetic studies of human hypertension. Nephrol Dial Transplant 1996; 11:927-929.
    • (1996) Nephrol Dial Transplant , vol.11 , pp. 927-929
    • Sharma, A.M.1
  • 51
    • 0033305356 scopus 로고    scopus 로고
    • Molecular basis of human salt-sensitivity: The role of the 11β-hydroxysteroid dehydrogenase type 2
    • 51 Lovati E, Ferrari P, Dick B, Jostarndt K, Frey BM, Frey FJ, et al. Molecular basis of human salt-sensitivity: the role of the 11β-hydroxysteroid dehydrogenase type 2. J Clin Endocrinol Metab 1999; 84:3745-3749.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3745-3749
    • Lovati, E.1    Ferrari, P.2    Dick, B.3    Jostarndt, K.4    Frey, B.M.5    Frey, F.J.6
  • 52
    • 0029847585 scopus 로고    scopus 로고
    • Urinary free cortisone and the assessment of 11β-hydroxysteroid dehydrogenase activity in man
    • 52 Palermo M, Shackleton CHL, Mantero F, Stewart PM. Urinary free cortisone and the assessment of 11β-hydroxysteroid dehydrogenase activity in man. Clin Endocrinol 1996; 45:605-611.
    • (1996) Clin Endocrinol , vol.45 , pp. 605-611
    • Palermo, M.1    Shackleton, C.H.L.2    Mantero, F.3    Stewart, P.M.4
  • 53
    • 0030814349 scopus 로고    scopus 로고
    • Mutations in the 11β-hydroxysteroid dehydrogenase type II enzyme associated with hypertension and possibly stillbirth
    • 53 Krozowski ZS, Stewart PM, Obeyesekere VR, Li K, Ferrari P. Mutations in the 11β-hydroxysteroid dehydrogenase type II enzyme associated with hypertension and possibly stillbirth. Clin Exp Hypertens 1997; 19:519-529.
    • (1997) Clin Exp Hypertens , vol.19 , pp. 519-529
    • Krozowski, Z.S.1    Stewart, P.M.2    Obeyesekere, V.R.3    Li, K.4    Ferrari, P.5
  • 54
    • 0028171669 scopus 로고
    • 11β-Hydroxysteroid dehydrogenase in the rat placenta: Developmental changes and the effects of altered glucocorticoid exposure
    • 54 Burton PJ, Waddell BJ. 11β-Hydroxysteroid dehydrogenase in the rat placenta: developmental changes and the effects of altered glucocorticoid exposure. J Endocrinol 1994; 143:505-513.
    • (1994) J Endocrinol , vol.143 , pp. 505-513
    • Burton, P.J.1    Waddell, B.J.2
  • 55
    • 0024542325 scopus 로고
    • Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease
    • 55 Barker DJ, Osmond C, Golding J, Kuh D, Wadsworth ME. Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease. Br Med J 1989; 298:564-567.
    • (1989) Br Med J , vol.298 , pp. 564-567
    • Barker, D.J.1    Osmond, C.2    Golding, J.3    Kuh, D.4    Wadsworth, M.E.5
  • 56
    • 0029989854 scopus 로고    scopus 로고
    • Prenatal glucocorticoid exposure leads to offspring hyperglycaemia in the rat: Studies with the 11β-hydroxysteroid dehydrogenase inhibitor carbenoxolone
    • 56 Lindsay RS, Lindsay RM, Waddell BJ, Seckl JR. Prenatal glucocorticoid exposure leads to offspring hyperglycaemia in the rat: studies with the 11β-hydroxysteroid dehydrogenase inhibitor carbenoxolone. Diabetologia 1996; 39:1299-1305.
    • (1996) Diabetologia , vol.39 , pp. 1299-1305
    • Lindsay, R.S.1    Lindsay, R.M.2    Waddell, B.J.3    Seckl, J.R.4
  • 57
    • 0027530474 scopus 로고
    • Dysfunction of placental glucocorticoid barrier: Link between fetal environment and adult hypertension?
    • 57 Edwards C, Benediktsson R, Lindsay RS, Seckl JR. Dysfunction of placental glucocorticoid barrier: link between fetal environment and adult hypertension? Lancet 1993; 1:355-357.
    • (1993) Lancet , vol.1 , pp. 355-357
    • Edwards, C.1    Benediktsson, R.2    Lindsay, R.S.3    Seckl, J.R.4
  • 59
    • 0031697031 scopus 로고    scopus 로고
    • Placental 11β-hydroxysteroid dehydrogenase activity in normotensive and pre-eclamptic pregnancies
    • 59 McCalla CO, Nacharaju VL, Muneyyirci-Delale O, Glasgow S, Feldman JG. Placental 11β-hydroxysteroid dehydrogenase activity in normotensive and pre-eclamptic pregnancies. Steroids 1998; 63:511-515.
    • (1998) Steroids , vol.63 , pp. 511-515
    • McCalla, C.O.1    Nacharaju, V.L.2    Muneyyirci-Delale, O.3    Glasgow, S.4    Feldman, J.G.5
  • 60
    • 0025848709 scopus 로고
    • Evidence that high dose cortisol-induced Na+ retention in man is not mediated by the mineralocorticoid receptor
    • 60 Montrella-Waybill M, Clore JN, Schoolwerth AC, Watlington CO. Evidence that high dose cortisol-induced Na+ retention in man is not mediated by the mineralocorticoid receptor. J Clin Endocrinol Metab 1991; 72:1060-1066.
    • (1991) J Clin Endocrinol Metab , vol.72 , pp. 1060-1066
    • Montrella-Waybill, M.1    Clore, J.N.2    Schoolwerth, A.C.3    Watlington, C.O.4
  • 61
    • 0030462275 scopus 로고    scopus 로고
    • Dose-response relationships and mineralocorticoid activity in cortisol-induced hypertension in humans
    • 61 Williamson PM, Kelly JJ, Whitworth JA. Dose-response relationships and mineralocorticoid activity in cortisol-induced hypertension in humans. J Hypertens Suppl 1996; 14:S37-S41.
    • (1996) J Hypertens Suppl , vol.14
    • Williamson, P.M.1    Kelly, J.J.2    Whitworth, J.A.3
  • 62
    • 0014341097 scopus 로고
    • Mode of spirolactone action: Competitive inhibition of aldosterone binding to kidney mineralocorticoid receptors
    • 62 Fanestil DD. Mode of spirolactone action: competitive inhibition of aldosterone binding to kidney mineralocorticoid receptors. Biochem Pharmacol 1968; 17:2240-2242.
    • (1968) Biochem Pharmacol , vol.17 , pp. 2240-2242
    • Fanestil, D.D.1
  • 63
    • 0027071656 scopus 로고
    • Central hypertensinogenic effects of glycyrrhizic acid and carbenoxolone
    • 63 Gomez-Sanchez EP, Gomez-Sanchez CE. Central hypertensinogenic effects of glycyrrhizic acid and carbenoxolone. Am J Physiol 1992; 263:E1125-E1130.
    • (1992) Am J Physiol , vol.263
    • Gomez-Sanchez, E.P.1    Gomez-Sanchez, C.E.2
  • 64
    • 0029939426 scopus 로고    scopus 로고
    • Mineralocorticoid receptors in the central nervous system
    • 64 Funder JW. Mineralocorticoid receptors in the central nervous system. J Steroid Biochem Mol Biol 1996; 56:179-183.
    • (1996) J Steroid Biochem Mol Biol , vol.56 , pp. 179-183
    • Funder, J.W.1
  • 65
    • 0032506549 scopus 로고    scopus 로고
    • Cure of apparent mineralocorticoid excess by kidney transplantation
    • 65 Palermo M, Cossu M, Shackleton CH. Cure of apparent mineralocorticoid excess by kidney transplantation. N Engl J Med 1998; 339:1787-1788.
    • (1998) N Engl J Med , vol.339 , pp. 1787-1788
    • Palermo, M.1    Cossu, M.2    Shackleton, C.H.3
  • 68
    • 15144343124 scopus 로고    scopus 로고
    • Structural analysis and evaluation of the 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) gene in human essential hypertension
    • 68 Brand E, Kato N, Chatelain N, Krozowski ZS, Jeunemaitre X, Corvol P, et al. Structural analysis and evaluation of the 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) gene in human essential hypertension. J Hypertens 1998; 16:1627-1633.
    • (1998) J Hypertens , vol.16 , pp. 1627-1633
    • Brand, E.1    Kato, N.2    Chatelain, N.3    Krozowski, Z.S.4    Jeunemaitre, X.5    Corvol, P.6
  • 69
    • 0025784936 scopus 로고
    • Inhibitory effects of gossypol on corticosteroid 11β-hydroxysteroid dehydrogenase from guinea pig kidney: A possible mechanism for causing hypokalemia
    • 69 Sang GW, Lorenzo NJ, Reidenberg MM. Inhibitory effects of gossypol on corticosteroid 11β-hydroxysteroid dehydrogenase from guinea pig kidney: a possible mechanism for causing hypokalemia. J Steroid Biochem 1991; 39:169-176.
    • (1991) J Steroid Biochem , vol.39 , pp. 169-176
    • Sang, G.W.1    Lorenzo, N.J.2    Reidenberg, M.M.3
  • 70
    • 0026476266 scopus 로고
    • Inhibition of 11β-hydroxysteroid dehydrogenase by gossypol and bioflavonoids
    • 70 Song D, Lorenzo BJ, Reidenberg MM. Inhibition of 11β-hydroxysteroid dehydrogenase by gossypol and bioflavonoids. J Lab Clin Med 1992; 120:792-797.
    • (1992) J Lab Clin Med , vol.120 , pp. 792-797
    • Song, D.1    Lorenzo, B.J.2    Reidenberg, M.M.3
  • 72
    • 0030068190 scopus 로고    scopus 로고
    • Endogenous renal 11β-hydroxysteroid dehydrogenase inhibitory factors in patients with low-renin essential hypertension
    • 72 Takeda Y, Miyamori I, Iki K, Inaba S, Furukawa K, Hatakeyama H, et al. Endogenous renal 11β-hydroxysteroid dehydrogenase inhibitory factors in patients with low-renin essential hypertension. Hypertension 1996; 27:197-201.
    • (1996) Hypertension , vol.27 , pp. 197-201
    • Takeda, Y.1    Miyamori, I.2    Iki, K.3    Inaba, S.4    Furukawa, K.5    Hatakeyama, H.6
  • 73
    • 0031035845 scopus 로고    scopus 로고
    • Kidney 11βHSD2 is inhibited by glycyrrhetinic acid-like factors in human urine
    • 73 Lo YH, Sheff MF, Latif SA, Ribeiro C, Silver H, Brem AS, et al. Kidney 11βHSD2 is inhibited by glycyrrhetinic acid-like factors in human urine. Hypertension 1997; 29 (1 Pt 2):500-505.
    • (1997) Hypertension , vol.29 , Issue.1 PT 2 , pp. 500-505
    • Lo, Y.H.1    Sheff, M.F.2    Latif, S.A.3    Ribeiro, C.4    Silver, H.5    Brem, A.S.6
  • 74
    • 0031613529 scopus 로고    scopus 로고
    • Impact of dietary Na+ on glycyrrhetinic acid-like factors (kidney 11β-(HSD2)-GALFs) in human essential hypertension
    • 74 Morris DJ, Lo YH, Litchfield WR, Williams GH. Impact of dietary Na+ on glycyrrhetinic acid-like factors (kidney 11β-(HSD2)-GALFs) in human essential hypertension. Hypertension 1998; 31 (Part 2):469-472.
    • (1998) Hypertension , vol.31 , Issue.PART 2 , pp. 469-472
    • Morris, D.J.1    Lo, Y.H.2    Litchfield, W.R.3    Williams, G.H.4
  • 75
    • 0029968764 scopus 로고    scopus 로고
    • 11α-and 11β-Hydroxyprogesterone, potent inhibitors of 11 beta-hydroxysteroid dehydrogenase, possess hypertensinogenic activity in the rat
    • 75 Souness GW, Morris DJ. 11α-and 11β-Hydroxyprogesterone, potent inhibitors of 11 beta-hydroxysteroid dehydrogenase, possess hypertensinogenic activity in the rat. Hypertension 1996; 27 (3 Pt 1):421-425.
    • (1996) Hypertension , vol.27 , Issue.3 PT 1 , pp. 421-425
    • Souness, G.W.1    Morris, D.J.2


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