A new polymorphic restriction site in the human 11β-hydroxysteroid dehydrogenase type 2 gene

Journal of Clinical Endocrinology and Metabolism

Volumn 83, Issue 5, 1998, Pages 1814-1817

  Smolenicka, Z ^a   Bach, E ^a   Schaer, A ^a   Liechti Gallati, S ^a   Frey, B M ^a   Frey, F J ^a   Ferrari, P ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE;

ADULT; AGED; ARTICLE; DIABETES MELLITUS; DISEASE ASSOCIATION; DNA POLYMORPHISM; DNA SEQUENCE; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION; GENE MUTATION; GENOTYPE; HUMAN; HYPERTENSION; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RESTRICTION SITE; SEQUENCE ANALYSIS;

11-BETA-HYDROXYSTEROID DEHYDROGENASES; ADULT; AGED; BASE SEQUENCE; CODON; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DIABETES MELLITUS; EXONS; FEMALE; HUMANS; HYDROXYSTEROID DEHYDROGENASES; HYPERTENSION; ISOENZYMES; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH;

EID: 0031723991     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.83.5.1814     Document Type: Article

References (22)

1. Edwards CRW, Burt D, McIntyre MA, et al.. 1988 Localisation of 11ß-hydroxysteroid dehydrogenase-tissue specific protector of the mineralocorticoid receptor. Lancet. 2:986-989.
2. Funder JW, Pearce PT, Smith R, Smith AI. 1988 Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated. Science. 243:583-585.
3. Agarwal AK, Monder C, Eckstein B, White PC. 1989 Cloning and expression of rat cDNA encoding corticosteroid 11ß-dehydrogenase. J Biol Chem. 264:18939-18943.
4. Albiston AL, Obeyesekere VR, Smith RE, Krozowski ZS. 1994 Cloning and tissue distribution of the human 11ß-hydroxysteroid dehydrogenase type 2 enzyme. Mol Cell Endocrinol. 105:R11-R17.
5. Naray-Fejes-Toth A, Watlington CO, Fejes-Toth G. 1991 11ß-hydroxysteroid dehydrogenase activity in the renal target cells of aldosterone. Endocrinology. 129:17-21.
6. Mune T, Rogerson FM, Nikkila H, Agarwal AK, White PC. 1995 Human hypertension caused by mutations in the kidney isozyme of 11ß-hydroxysteroid dehydrogenase. Nature Genetics. 10:394-399.
7. Ferrari P, Obeyesekere VR, Li K, et al. 1996 Point mutations abolish 11ß-hydroxysteroid dehydrogenase type II activity in three families with the congenital syndrome of apparent mineralocorticoid excess. Mol Cell Endocrinol. 119:21-24.
8. Ulick S, Levine LS, Gunczler P, et al. 1979 A syndrome of apparent mineralocorticoid excess associated with defects in the peripheral metabolism of Cortisol. J Clin Endocrinol Metab. 49:757-763.
9. Beretta-Piccoli C, Davies DL, Brown JJ, et al. 1982 The relation of arterial pressure with plasma and body electrolytes is similar in Conn's syndrome and essential hypertension. Clin Sci. 63:89-92.
10. Walker BR, Stewart PM, Shackleton C, Padfield PL, Edwards C. 1993 Deficient inactivation of cortisol by 11ß-hydroxysteroid dehydrogenase in essential hypertension. Clin Endocrinol. 39:221-227.
11. Soro A, Ingram MC, Tonolo G, Glorioso N, Friser R. 1995 Evidence of coexisting changes in 11ß-hydroxysteroid dehydrogenase and 5ß-reductase activity in subjects with untreated essential hypertension. Hypertension. 25:67-70.
12. Watson B, Bergamn SM, Myracle A, Callen DF, Acton RT, Warnock DG. 1996 Genetic association of flanking microsatellites with essential hypertension in blacks. Hypertension. 28:478-482.
13. Vierhapper H, Derfler K, Nowotny P, Hollenstein U, Waldhausl W. 1991 Impaired conversion of cortisol to cortisone in chronic renal insufficiency-a cause of hypertension or an epiphenomenon? Acta Endocrinol (Copenh). 125:160-164.
14. Weidmann P, Ferrari P. 1991 Central role of sodium in diabetic hypertension. Diabetes Care. 14:220-232.
15. Budowle B, Chakraborty R, Giusti AM, Eisenberg AJ, Allen RC. 1991 Analysis of the VNTR locus D1S80 by the PCR followed by high-resolution PAGE. Am J Hum Genet. 48:137-144.
16. Ferrari P, Obeyesekere VR, Li K, Andrews RK, Krozowski ZS. 1996 The 11ß-hydroxysteroid dehydrogenase type II enzyme: biochemical consequences of the congenital R337C mutation. Steroids 61:197-200.
17. Jornavall H, Persson B, Krook M, et al. 1995 Short-chain dehydrogenase reductases (SDR). Biochemistry 34:6003-6013.
18. Obeyesekere VR, Li KX, Ferrari P, Krozowski ZS. 1997 Truncation of the N- and C-terminal regions of human 11ß-hydroxysteroid dehydrogenase type 2 and effects on solubility and bidirectional enzyme activity. Mol Cell Endocrinol. 131:173-182.
19. Brazy PC, Stead WW, Fitzwilliam JF. 1989 Progression of renal insufficiency: role of blood pressure. Kidney Int. 35:670-674.
20. Beretta-Piccoli C, Weidmann P, deChatel R, Reubi F. 1976 Hypertension associated with early stage kidney disease. Complementary roles of circulating renin, the body sodium/volume state and duration of hypertension. Am J Med. 61:739-746.
21. Rutledge DR, Sun Y, Ross EA. 1995 Polymorphism within the atrial natriuretic peptide gene in essential hypertension J Hypertens. 13;953-955.
22. Schorr U, Beige J, Ringel J, et al. 1997 Hpa II polymorphism of the atrial natriuretic peptide gene and the blood pressure response to salt intake in normotensive men. J Hypertens. 15:715-718.